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Acute pericarditis (AP) is the second most common cardiac cause of chestpain, diagnosed when at least two of the following criteria are met: characteristic pleuritic chestpain, pericardial rub on auscultation, new typical ECG changes (such as widespread ST-elevation or PR-depression) and pericardial effusion on imaging.
The case reports Case 1 involves a 26 year old man who developed pericarditis after the Pfizer vaccine. Pericarditis, an inflammation of the sac the heart lives in, developed about 7 days after the Pfizer vaccine. The diagnosis was made based on classic findings of inflammation on an electrocardiogram associated with acute chestpain.
Recall from this post referencing this study that "reciprocal STD in aVL is highly sensitive for inferior OMI (far better than STEMI criteria) and excludes pericarditis, but is not specific for OMI." See this case: Persistent ChestPain, an Elevated Troponin, and a Normal ECG. A patient with OMI can have a totally normal ECG!"
Scenario 1 : The patient presents with 24 hours of substernal chestpain. The exception is with postinfarction pericarditis , in which a completed transmural infarct results in inflammation of the subepicardial myocardium and STE in the distribution of the infarct, and which results in increased STE and large upright T-waves.
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