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Circulation, Ahead of Print. Smokeless oral nicotine products are addictive, and their use has potential adverse effects on some but not all biomarkers of cardiovascular risk. The use of some types of these products, for instance, is associated with an increased mortality risk in those with ischemic heart or cerebrovasculardisease.
Among other potential contributors to atheroma formation and cerebrovasculardisease, the gut microbiome has become increasingly implicated as a mediator of vascular risk. Several of these toxic metabolites, including trimethylamine and trimethylamine Noxide, have been extensively studied in cardiovascular and cerebrovasculardisease.
BackgroundBrain arterial diameters (BADs) are novel imaging biomarkers of cerebrovasculardisease, cognitive decline, and dementia. Brain arterial diameters for 13 segments were measured and averaged to obtain a global measure of BADs as well as the posterior and anterior circulations.
Atherosclerotic cardiovascular disease (ASCVD), caused by plaque buildup in arterial walls, is one of the leading causes of disability and death worldwide.1,2 1,2 ASCVD causes or contributes to conditions that include coronary artery disease (CAD), cerebrovasculardisease, and peripheral vascular disease (inclusive of aortic aneurysm).3
Image courtesy: ASA/AHA christine.book Mon, 01/22/2024 - 18:03 January 23, 2024 — Focused on delivering the latest scientific advancements and new treatments in cerebrovasculardiseases and brain health science from around the world, this year's International Stroke Conference, ISC 2024 , will be held Feb. 7-9 in Phoenix, Arizona.
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