Biomarkers Cardiovascular Disease Dementia 
Dr. Paddy Barrett
SEPTEMBER 19, 2023
I am going to start with the answer to the question of whether statins cause dementia and then provide the details backing up my answer. Statins do not cause dementia. But if you are someone who thinks that statins do cause dementia and you need to see the evidence to refute that claim, then read on. The answer is: No.
Dr. Paddy Barrett
AUGUST 22, 2023
Being a carrier of the APOE4 gene variant is associated with higher rates of the most common type of dementia, late-onset dementia. Of those with late-onset dementia, up to 65% are carriers of the APOE4 gene variant 1. A subsequent article will focus on the risk of late-onset dementia for those carriers of APOE4.
Dr. Paddy Barrett
FEBRUARY 21, 2025
Type 2 Diabetes When it comes to the increasing the risk of major chronic diseases such as cardiovascular disease, many cancers and dementia, type 2 diabetes plays a huge role. For example, people with type 2 diabetes are 10 times more likely to develop cardiovascular disease than those who do not have diabetes 10.
Circulation
NOVEMBER 14, 2024
BACKGROUND:Many studies have explored whether individual plasma protein biomarkers improve cardiovascular disease risk prediction. We sought to investigate the use of a plasma proteomics-based approach in predicting different cardiovascular outcomes.METHODS:Among 51 859 UK Biobank participants (mean age, 56.7
Hypertension Journal
SEPTEMBER 21, 2023
There has been considerable progress in the prevention and treatment of cardiovascular disease, reducing the population burden of cardiovascular morbidity and mortality. Here, we review these obstacles, motivated by SPRINT and the context of selecting an appropriate cognitive end point for future preventive randomized trials.
Dr. Paddy Barrett
SEPTEMBER 13, 2024
Insulin resistance is a major risk factor for the leading causes of death, the leading one being cardiovascular disease. Understanding where you sit on this continuum is a key part of defining your future risk of heart disease but also dementia, and many cancers. The higher the score, the higher the risk. Circulation.
Dr. Malcolm Kendrick
OCTOBER 30, 2024
The hypothesis that a raised cholesterol level causes heart disease [atherosclerotic cardiovascular disease (ASCVD)] is possibly the single most powerful idea in medicine. Which remains the single most influential study on cardiovascular disease, ever. At least some of it. It was simply a matter of time.
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