Frontiers in Cardiovascular Medicine

FEBRUARY 10, 2025

Despite its known correlations with risk of cardiovascular disease, awareness and testing for Lipoprotein (a) lags that of other serological markers with estimates that less than 1% of the US population have undergone screening.

Cardiovascular Disease 52

Cardiovascular Disease Biomarkers Obesity Outcomes 52

Journal of the American Heart Association

JANUARY 12, 2024

ABSTRACT: Albuminuria, an established biomarker of the progression of chronic kidney disease, is also recognized as a biomarker for the risk of cardiovascular disease. There are now several therapeutic agents that can lead to albuminuria lowering and a reduction in cardiovascular risk.

Cardiovascular Disease 71

Cardiovascular Disease Risk Factors Coronary Artery Disease Kidney Disease 71

Cardiovascular Diabetology

NOVEMBER 1, 2024

Dysglycemia and insulin resistance increase type 2 diabetes (T2D) and cardiovascular disease (CVD) risk, yet associations with specific glucose-insulin homeostatic biomarkers have been inconsistent. Vitamin D.

Cardiovascular Disease 52

Cardiovascular Disease Biomarkers Diabetes Research 52

Cardiovascular Diabetology

MARCH 20, 2025

The triglyceride-glucose index serves as a dependable biomarker for gauging insulin resistance linked to cardiovascular disease. Our study was designed to investigate how the trajectory of the triglyceride-glu.

Heart Failure 86

Heart Failure Biomarkers Cardiovascular Disease Diabetes 86

Frontiers in Cardiovascular Medicine

AUGUST 7, 2024

In recent years, S100 calcium binding protein A8/A9 (S100A8/A9) derived from neutrophils has attracted increasing attention as an important warning protein for cardiovascular disease.

Cardiovascular Disease 52

Cardiovascular Disease Myocardial Infarction Atherosclerosis Biomarkers 52

Frontiers in Cardiovascular Medicine

JULY 10, 2024

Emerging evidence indicates that uromodulin may serve as a potential biomarker extending beyond renal function. Recent clinical investigations and Mendelian randomization studies have unveiled a discernible association between urinary regulatory protein levels and cardiovascular events and mortality.

Cardiovascular Disease 52

Cardiovascular Disease Physiology Biomarkers 52

Circulation

DECEMBER 4, 2023

BACKGROUND:It is unknown whether dietary intake of polyunsaturated fatty acids (PUFA) modifies the cardiovascular disease (CVD) risk associated with a family history of CVD. Circulation, Ahead of Print. The pooled relative risk of CVD associated with the combined exposure to low EPA/DHA, and family history was 1.41 (95% CI, 1.30–1.54),

Cardiovascular Disease 75

Cardiovascular Disease Biomarkers Circulation 75

Medical Xpress - Cardiology

FEBRUARY 23, 2024

While cholesterol is a major contributor to heart disease, a recent study from Brigham and Women's Hospital, a founding member of Mass General Brigham, found that a glycan biomarker of IgG is also an important predictor for cardiovascular diseases (CVD).

Cholesterol 104

Cholesterol Biomarkers Heart Disease Cardiovascular Disease 104

Circulation

NOVEMBER 11, 2024

Personalized interventions are deemed vital given the intricate characteristics, advancement, inherent genetic composition, and diversity of cardiovascular diseases (CVDs). The top ten percent of commonly observed significant biomarkers were evaluated using four unique ML classifiers.

Biomarkers 40

Biomarkers Cardiovascular Disease Circulation 40

DAIC

FEBRUARY 3, 2025

This clearance comes in advance of disease-modifying therapies on the horizon expected to help clinicians use this biomarker to guide patients to improved cardiovascular health, saidBrad Moore, president and CEO at Roche Diagnostics North America. The development of the Tina-quant Lipoprotein (a) Gen.2 J Clin Lipidol.

Cardiovascular Disease 52

Cardiovascular Disease Aortic valve Biomarkers Innovation 52

Frontiers in Cardiovascular Medicine

JUNE 3, 2024

Indoleamine 2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO) serve as the initial and pivotal enzymes of the KP, with IDO playing important and intricate roles in cardiovascular diseases. Multiple studies have indicated that kynurenine (KYN) may serve as a potential biomarker for several adverse cardiovascular events.

Cardiovascular Disease 52

Cardiovascular Disease Atherosclerosis Myocardial Infarction Physiology 52

Cardiovascular Diabetology

MAY 6, 2024

The association between iron biomarkers and cardiovascular disease risk factors (CVD-RFs) remains unclear. We aimed to (1) evaluate the cross-sectional and longitudinal associations between iron biomarkers (se.

Risk Factors 52

Risk Factors Biomarkers Cardiovascular Disease Research 52

Heart BMJ

MAY 10, 2024

While progress has been made in the management of most aspects of cardiovascular disease, the incidence and prevalence of heart failure (HF) remains high. Biomarkers have dramatically impacted the way patients with HF are evaluated and managed. The most studied biomarkers in HF are natriuretic peptides (NPs).

Biomarkers 52

Biomarkers Heart Failure Physiology Article 52

Science Daily - Heart Disease

NOVEMBER 28, 2023

A new study found that alcohol consumption may have counteractive effects on CVD risk, depending on the biological presence of certain circulating metabolites -- molecules that are produced during or after a substance is metabolized and studied as biomarkers of many diseases.

Cardiovascular Disease 65

Cardiovascular Disease Biomarkers Circulation Research 65

The American Journal of Cardiology

JANUARY 10, 2024

An inverse association of education level with cardiovascular diseases has been documented in observational studies, yet the causality and potential m…

Education 40

Education Cardiovascular Disease Biomarkers Document 40

Frontiers in Cardiovascular Medicine

MARCH 9, 2025

BackgroundEmerging genetic and observational evidence indicates that remnant cholesterol (RC) is a significant residual risk factor for cardiovascular diseases. However, there is a relative paucity of evidence exploring the correlation among RC, lipid ratios, and atherosclerotic lesion severity.

Cholesterol 52

Cholesterol Heart Disease Stenosis Risk Factors 52

Physiologically Speaking

JULY 24, 2024

We talk about why the ketogenic diet is helpful for people with diabetes and then dive into the details of each study to explore how 10 years on the diet affected cardiovascular health risk factors and clinical biomarkers. Andrew posted two great threads about the papers on X. You can check those out below.

Diabetes 115

Diabetes Diet Physiology Biomarkers 115

Cardiovascular Diabetology

JANUARY 2, 2024

The triglyceride-glucose (TyG) index is regarded as a sophisticated surrogate biomarker for insulin resistance, offering a refined means for evaluating cardiovascular diseases (CVDs). However, prospective coho.

Cardiovascular Disease 40

Cardiovascular Disease Biomarkers Research 40

Cardiovascular Diabetology

APRIL 1, 2025

Cardiovascular diseases (CVD) remain the leading cause of morbidity and mortality globally. Traditional risk models, primarily based on established risk factors, often lack the precision needed to accurately p.

Risk Factors 52

Risk Factors Biomarkers Cardiovascular Disease Research 52

Frontiers in Cardiovascular Medicine

JULY 2, 2024

Cardiovascular diseases account for a significant portion of the worldwide mortality rate. This aroused interest among the specialised scientific community, seeking for solutions based on non-clinical and clinical investigations, to shed light onto the physio-pathology of cardiovascular impairment.

Atherosclerosis 52

Atherosclerosis Cardiovascular Disease Physiology Biomarkers 52

Circulation

MARCH 9, 2025

Many authors have hypothesized that albuminuria reflects widespread endothelial dysfunction, but additional work is needed to uncover whether albuminuria is directly pathologic or causative of cardiovascular disease. However, albuminuria may develop through unique mechanisms across these distinct clinical phenotypes.

Kidney Disease 83

Kidney Disease Biomarkers Heart Failure Risk Factors 83

Journal of Cardiothoracic Surgery

JANUARY 9, 2025

MicroRNAs (miRNAs) are closely related to cardiovascular diseases, including chronic heart failure (CHF). Endothelial dysfunction can lead to heart failure. The purpose of this study was to evaluate the clinic.

Heart Failure 52

Heart Failure Biomarkers Cardiovascular Disease Research 52

Journal of Cardiothoracic Surgery

JANUARY 16, 2025

Atherosclerosis (AS) is increasingly recognized as a chronic inflammatory disease that significantly compromises vascular health and acts as a major contributor to cardiovascular diseases. Advancements in lipi.

Atherosclerosis 52

Atherosclerosis Biomarkers Cardiovascular Disease Research 52

The British Journal of Cardiology

JUNE 11, 2024

Cardiovascular diseases (CVDs) have been reported to occur in a significant number of patients diagnosed with coronavirus disease 2019 (COVID-19). Cardiovascular consultation had been requested for all of the patients based on their primary clinical examination, vital signs, and electrocardiogram (ECG).

COVID-19 40

COVID-19 Cardiovascular Disease Angina Chest Pain 40

Cardiovascular Diabetology

OCTOBER 13, 2024

Triglyceride (TG) and its related metabolic indices are recognized as important biomarker gauging cardiovascular diseases. This study aimed to explore the association between multiple TG-derived metabolic indi.

Biomarkers 52

Biomarkers Heart Disease Cardiovascular Disease Diabetes 52

JAMA Cardiology

FEBRUARY 11, 2025

The OCEAN(a)-DOSE multicenter randomized clinical trial among 281 patients with atherosclerotic cardiovascular disease assesses the effects of olpasiran on oxidized phospholipids, high-sensitivity interleukin 6, and high-sensitivity C-reactive protein.

Biomarkers 40

Biomarkers Cardiovascular Disease 40

Circulation

NOVEMBER 11, 2024

Introduction/Background:According to the American Heart Association, the accumulation of plaque in the walls of arteries is identified as the primary cause of atherosclerotic cardiovascular disease (ASCVD). While hsCRP shows moderate diagnostic accuracy, it is not sufficient as a standalone ASCVD risk diagnostic marker.

Biomarkers 40

Biomarkers Cardiovascular Disease Laboratory Plaque 40

Frontiers in Cardiovascular Medicine

JULY 17, 2024

The triglyceride–glucose (TyG) index, proven to be a crucial insulin resistance biomarker (better than the Homeostasis Model Assessment for Insulin Resistance), is simple and non-invasive.

Heart Failure 64

Heart Failure Atherosclerosis Biomarkers Obesity 64

Frontiers in Cardiovascular Medicine

FEBRUARY 5, 2024

Despite developments in circulating biomarker and imaging technology in the assessment of cardiovascular disease, the surveillance and diagnosis of heart transplant rejection has continued to rely on histopathologic interpretation of the endomyocardial biopsy.

Heart Transplant 64

Heart Transplant Transplant Biomarkers Technology 64

CardiacWire

JANUARY 24, 2024

CardioSignal has already developed digital biomarkers for AFib and heart failure, while more solutions could be on the way for aortic stenosis, coronary artery disease, and pulmonary artery hypertension.

AFIB 75

AFIB Coronary Artery Disease Biomarkers Heart Failure 75

Circulation: Genomic and Precision Medicine

FEBRUARY 13, 2024

Circulation: Genomic and Precision Medicine, Ahead of Print.

Cardiovascular Disease 40

Cardiovascular Disease Biomarkers Circulation 40

Journal of Cardiovascular Pharmacology

JULY 18, 2012

Abstract: The renin angiotensin aldosterone system (RAAS) is a paramount target for the pharmacological treatment of cardiovascular diseases. The model also encompassed the PK of intravenous and oral enalapril and its conversion to enalaprilat.

Physiology 40

Physiology Biomarkers Pharmacology Cardiovascular Disease 40

DAIC

JUNE 4, 2024

I am excited about the potential of the FAI-Score biomarker, which has promising prognostic value beyond existing CT-based methods such as plaque, calcium scoring, and CAD-RADS based interpretation." Details of the study, included in a written statement issued by Caristo Diagnostics, follow. fold higher risk for cardiac mortality and 5.5-fold

Technology 116

Technology Heart Attack Heart attacks Coronary Artery Disease 116

Frontiers in Cardiovascular Medicine

JANUARY 7, 2024

Non-coding RNAs, comprising of microRNAs (miRNAs), long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs), are non-protein coding RNA transcripts, which are implicated in various cardiovascular diseases. Finally, we discuss the potential of ncRNAs as biomarkers and potential novel therapeutic targets for future HFpEF treatment.

Preserved Ejection Fraction 59

Preserved Ejection Fraction Heart Failure Biomarkers Cardiovascular Disease 59

HeartRhythm

APRIL 30, 2024

Leukocyte telomere length (LTL) is a well-established biomarker linked to cardiovascular disease, with shorter LTL associated with increased severity of heart failure (HF) outcomes. It is also well known that atrial fibrillation (AF) and HF are closely related and often coexist.

Atrial Fibrillation 40

Atrial Fibrillation Heart Failure Biomarkers Cardiovascular Disease 40

Coronary Artery Disease Journal

OCTOBER 30, 2023

Introduction Several blood inflammatory markers, such as high-sensitivity C-reactive protein (hs-CRP), neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR), are linked to increased risk for cardiovascular diseases.

Cardiac Rehabilitation 52

Cardiac Rehabilitation Heart Disease Biomarkers Cardiovascular Disease 52

Frontiers in Cardiovascular Medicine

JANUARY 2, 2024

Artificial intelligence (AI) has emerged as a promising field in cardiovascular disease (CVD) research, offering innovative approaches to enhance diagnosis, treatment, and patient outcomes. This indicates that the future direction of AI cardiovascular research is predominantly directing toward neural networks and image analysis.As

Research 64

Research Cardiovascular Disease Biomarkers Innovation 64