DAIC

APRIL 9, 2024

The PROACT study reported no impact on cardiotoxicity biomarkers or secondary endpoints related to heart function among patients who took high doses of enalapril, an ACE inhibitor, along with high doses of anthracyclines. Anthracyclines are a well-established class of cancer drugs that are used to treat several types of cancer.

ACE Inhibitor 105

ACE Inhibitor Cancer Biomarkers Heart Failure 105

Journal of Clinical Investigation - Cardiology

SEPTEMBER 3, 2024

Obesity is a known driver of endometrial cancer. In this issue of the JCI, Gómez-Banoy and colleagues investigated a cohort of patients with advanced endometrial cancer treated with immune checkpoint inhibitors targeting the interaction between programmed cell death receptor-1 (PD-1) and its ligand (PD-L1).

Cancer 60

Cancer Obesity BMI Biomarkers 60

Society of Thoracic Surgeons - Surgeon

MAY 23, 2024

Video 8 in 8: Biomarker Testing and Neoadjuvant Immunotherapy for Resectable NSCLC kchalko Thu, 05/23/2024 - 09:56 In this video in the 8 in 8 Series, Dr. Dwight Owen (Ohio State University) discussed advances in biomarker testing and neoadjuvant immunotherapy for resectable non-small cell lung cancer.

Biomarkers 52

Biomarkers CME Cardiothoracic Cancer 52

Frontiers in Cardiovascular Medicine

FEBRUARY 11, 2024

Immune checkpoint inhibitors (ICIs) are monoclonal antibodies that block immune checkpoints and therefore activate immune cells, allowing them to recognize and attack cancer cells. ICIs have revolutionized oncology practice, but their use has been complicated by immune-related adverse events (irAEs).

Biomarkers 64

Biomarkers Circulation Cancer Outcomes 64

Heart BMJ

MAY 10, 2024

HF affects around a million people in the UK and has a worse prognosis than most cancers. Biomarkers have dramatically impacted the way patients with HF are evaluated and managed. Biomarkers have dramatically impacted the way patients with HF are evaluated and managed.

Biomarkers 52

Biomarkers Heart Failure Physiology Article 52

Heart BMJ

APRIL 15, 2024

Methods Participants with human epidermal growth factor receptor 2-positive breast cancer treated with trastuzumab±anthracycline ≥5 years previously were identified from a clinical database. Participants underwent clinical cardiovascular evaluation, ECG, cardiac biomarker evaluation and CMR.

Cancer 52

Cancer Risk Factors Biomarkers Cholesterol 52

HCPLive

FEBRUARY 12, 2024

The prominent clinical investigator joins to discuss adjuvant and neoadjuvant care research, as well as the application of biomarkers in personalized care.

Cancer 64

Cancer Biomarkers Research 64

Society of Thoracic Surgeons - Surgeon

NOVEMBER 3, 2023

Plan to attend Part 2 on Thursday, December 14, titled " Biomarker Testing and Neoadjuvant Immunotherapy for Resectable NSCLC." While both trials showed similar results, there are important differences in design, demographics, and patients’ outcomes.

Cancer 52

Cancer Webinar Biomarkers Hospital 52

Stroke Journal

JANUARY 30, 2025

Background:Approximately 50% of ischemic strokes in patients with cancer are classified as cryptogenic after standard evaluation. Patients with, compared to those without, a history of cancer were older (71 versus 65 years) and more often White (88% versus 74%) and non-Hispanic (94% versus 90%). versus 1.8

Cancer 40

Cancer Biomarkers Atrial Fibrillation Stroke 40

Stroke Journal

JANUARY 30, 2025

However, there are no existing data supporting an independent relationship between cancer and atrial cardiopathy, another atrial pathology associated with increased acute ischemic stroke (AIS) risk. The study exposure was active cancer. Active cancer was present in 9.6% of patients with atrial cardiopathy (n=50/520) and 10.4%

Cancer 40

Cancer Stroke Strokes Atrial Fibrillation 40

DAIC

FEBRUARY 2, 2024

The event is offered as an interdisciplinary and interspecialty course to provide clinicians and researchers with the tools needed to improve the cardiovascular (CV) health of cancer patients in everyday practice. 9-11, 2024, with program planners preparing a robust program. The opening Plenary session, “Perspective from the U.S.

Cardio Oncology 95

Cardio Oncology Cancer Pharmacology RN 95

Dr. Paddy Barrett

FEBRUARY 21, 2025

These stages can range from mild fatty liver infiltration to serious scarring and fibrosis terminating in liver cirrhosis and potentially liver cancer. Type 2 Diabetes When it comes to the increasing the risk of major chronic diseases such as cardiovascular disease, many cancers and dementia, type 2 diabetes plays a huge role.

Obesity 80

Obesity Diabetes Cardiovascular Disease Chronic Disease 80

Dr. Paddy Barrett

OCTOBER 11, 2024

I have covered this topic previously here , but it is clear that inflammation plays a major role in the initiation and progression of coronary artery disease, and the inflammatory biomarker hsCRP is tightly connected to this process. Obesity is the second leading cause of preventable cancers after smoking 9. N Engl J Med. 2024 Jun 21.

Obesity 84

Obesity Cancer Dementia Coronary Artery Disease 84

Journal of Clinical Investigation - Cardiology

JULY 15, 2024

Mutations in the tumor-suppressor genes BRCA1 and BRCA2 resulting in BRCA1/2 deficiency are frequently identified in breast, ovarian, prostate, pancreatic, and other cancers.

Cancer 56

Cancer Biomarkers 56

Circulation: Cardiovascular Quality & Outcomes

SEPTEMBER 2, 2024

BACKGROUND:Risk stratification strategies for cancer therapeuticsrelated cardiac dysfunction (CTRCD) rely on serial monitoring by specialized imaging, limiting their scalability. Circulation: Cardiovascular Quality and Outcomes, Volume 18, Issue 1 , Page e011504, January 1, 2025. positive screen), respectively. P<0.001]).CONCLUSIONS:AI

Cancer 40

Cancer Cardiomyopathy Echocardiogram Biomarkers 40

Journal of the American Heart Association

JANUARY 19, 2024

BackgroundPatients with acute ischemic stroke and active cancer have more severe neurological symptoms, elevated risks of stroke recurrence, and death compared with the general population. Journal of the American Heart Association, Ahead of Print. 30.78];P<0.05).ConclusionsElevated

Cancer 40

Cancer Stroke Strokes Outcomes 40

Society of Thoracic Surgeons - Surgeon

MARCH 8, 2024

Leah Backhus, thoracic surgeon and professor of cardiothoracic surgery at Stanford Medicine, discusses the surgeon’s role in managing patients with resectable non-small cell lung cancer.

Cardiothoracic 59

Cardiothoracic Biomarkers Cancer 59

Circulation: Genomic and Precision Medicine

FEBRUARY 24, 2025

Artificial intelligence is poised to transform cardio-oncology by enabling personalized care for patients with cancer, who are at a heightened risk of cardiovascular disease due to both the disease and its treatments.

Cardio Oncology 40

Cardio Oncology Cancer Biomarkers Cardiovascular Disease 40

Society of Thoracic Surgeons - Surgeon

MARCH 8, 2024

As key members of the multidisciplinary care team, thoracic surgeons play a pivotal role in the patient journey for resectable Non-Small Cell Lung Cancer. This includes consideration of biomarker testing during the diagnostic biopsy and resection stages, and the potential benefit of perioperative and adjuvant therapies.

Biomarkers 52

Biomarkers Cancer 52

DAIC

JUNE 11, 2024

Therefore, the ability to detect cardiac amyloidosis early is critical,” noted Jonathan Wall , PhD, director of the Amyloidosis and Cancer Theranostics Program and professor at the University of Tennessee Graduate School of Medicine in Knoxville, Tennessee.

Cardiomyopathy 105

Cardiomyopathy Echocardiogram Research Biomarkers 105

Science Daily - Heart Disease

SEPTEMBER 25, 2023

With the ability to map dozens of biomarkers at once, a new method could transform testing for conditions including heart disease and cancer.

Biomarkers 40

Biomarkers Cancer Heart Disease 40

Dr. Paddy Barrett

SEPTEMBER 13, 2024

Understanding where you sit on this continuum is a key part of defining your future risk of heart disease but also dementia, and many cancers. The further along the line of insulin resistance you sit, the higher your risk of all the leading causes of death, including heart disease, dementia and many cancers 5.

Risk Factors 105

Risk Factors Heart Disease Dementia Diabetes 105

Dr. Paddy Barrett

APRIL 26, 2024

They are dying less often from the two leading causes of death: Cardiovascular Disease and Cancer. To the point that those with 6 to 7 of the healthy factors in place had essentially eliminated the increased risk of dying from cardiovascular disease or cancer compared to those without type 2 diabetes.

Heart Disease 105

Heart Disease Coronary Artery Disease Diabetes Genetic predisposition 105

DAIC

MAY 8, 2024

If inflammation is successfully controlled, diseases – such as arthritis, pulmonary hypertension, Crohn's disease, inflammatory bowel diseases, diabetes, cancer and autoimmune diseases – can be treated more effectively. Zanos has long looked at the role of ultrasound in treating disease; in 2023, he published a paper along with Sangeeta S.

Ultrasound 115

Ultrasound Pulmonary Research Hypertension 115

Dr. Paddy Barrett

APRIL 12, 2024

Similar patterns have been observed for cardiovascular disease and also cancer. 2 [link] 3 Physical activity patterns and biomarkers of cardiovascular disease risk in hunter-gatherers. Over a 10-year time frame, compared to 4000 steps, taking 7000 steps every day resulted in a 51% reduction in all-cause mortality. More movement.

Quality of Life 124

Quality of Life Blood Pressure Exercise Chronic Disease 124

Frontiers in Cardiovascular Medicine

JANUARY 22, 2024

Moreover, Atezolizumab is actually under study in association with Ipilimumab for therapy of metastatic lung cancer. After treatments, cardiac cell lysis and secretion of biomarkers of cardiotoxicity (H-FABP, troponin-T, BNP, NT-Pro-BNP), NLRP3-inflammasome and Interleukin 1 and 6 were determined through colorimetric and enzymatic assays.

Biomarkers 64

Biomarkers Cancer 64

Dr. Anish Koka

MAY 16, 2023

It would be like diagnosing women with metastatic breast cancer, but finding that just as many women with metastatic breast cancer were alive in 5 years as women not diagnosed with breast cancer. If women have more MINOCA, but the diagnosis doesn’t lead to a worse prognosis… who cares? ” What is going on?

Chest Pain 52

Chest Pain Coronary Artery Disease Cancer Heart Attack 52

European Journal of Heart Failure

NOVEMBER 26, 2024

( A ) Univariable receiver operating characteristic (ROC) curves for all biomarkers. ( Abstract Aims Traditional cardiovascular (CV) biomarkers (high-sensitivity troponinT [hsTnT] and N-terminal pro-B-type natriuretic peptide [NT-proBNP]) are important to monitor cancer patients' cardiac function and to assess prognosis.

Biomarkers 40

Biomarkers Cancer Laboratory Cardiac Function 40

DAIC

DECEMBER 18, 2024

The current version of the CardioFlux Score analyzes 14 unique biomarkers that quantify the heart muscle's electrical activity and then compares those results to a benchmark of healthy, symptom-free individuals. What we've been doing with cancer for the past two decades, I see no reason why we can't do with heart disease."

Heart Disease 52

Heart Disease Technology Cardiac Function Biomarkers 52

Frontiers in Cardiovascular Medicine

JANUARY 7, 2024

age, sex, ACS presentation, history of hypertension, smoking, diabetes, prior myocardial infarction (MI), heart failure, prior ischemic stroke, and cancer], laboratory tests [i.e., positive cardiac biomarker, hemoglobin, platelet count, white blood cell (WBC) count], and treatment [i.e.,

Stents 64

Stents Stent Thrombosis Myocardial Infarction 64

Circulation: Cardiovascular Imaging

FEBRUARY 19, 2024

18F-flourodeoxyglucose resting amygdalar uptake, an imaging biomarker of stress-related neural activity, coronary inflammation (fat attenuation index), and high-risk plaque characteristics were assessed by coronary computed tomography angiography. versus 5.1%; adjusted hazard ratio, 3.62 [95% CI, 1.14–17.14];P=0.039) 6.69];P=0.030).CONCLUSIONS:Imaging-assessed

Atherosclerosis 40

Atherosclerosis Plaque Coronary Artery Disease Biomarkers 40

Society of Thoracic Surgeons - Allied Health

SEPTEMBER 23, 2022

Webinar The Changing Face of Pretreatment Nodal Staging for Patients with Lung Cancer kchalko Fri, 09/23/2022 - 12:27 October 6, 2022 Procedures to evaluate lymph nodes before lung cancer therapy, including endobronchial guided nodal aspiration and mediastinoscopy, can help diagnose and stage the patient effectively.

Cancer 52

Cancer Allied Health Webinar Biomarkers 52

Cardiometabolic Health Congress

MARCH 8, 2024

Her research focuses on women’s cardiovascular health and cardio-obstetrics, cardiovascular risk prediction using coronary artery calcium scores and biomarkers, lipids, and cardiometabolic diseases. Centers for Disease Control and Prevention and as a behavioral sciences intern at the American Cancer Society.

Cardiac Rehabilitation 59

Cardiac Rehabilitation Academic Diabetes Research 59

Society of Thoracic Surgeons - Research

APRIL 20, 2023

Hunter Mehaffey Distressed communities are associated with worse outcomes after coronary artery bypass surgery The Journal of Thoracic and Cardiovascular Surgery August 2019 Meghana Helder Regional and Temporal Trends in the Outcomes of Repairs for Acute Type A Aortic Dissections The Annals of Thoracic Surgery August 2019 Derrick Tam Surgical valve (..)

Research 52

Research Coronary Artery Bypass Graft Aortic valve Congenital 52

Society of Thoracic Surgeons - Research

APRIL 20, 2023

Hunter Mehaffey 1 Distressed communities are associated with worse outcomes after coronary artery bypass surgery The Journal of Thoracic and Cardiovascular Surgery August 2019 Meghana Helder 2 Regional and Temporal Trends in the Outcomes of Repairs for Acute Type A Aortic Dissections The Annals of Thoracic Surgery August 2019 Derrick Tam 2 Surgical (..)

Research 52

Research Coronary Artery Bypass Graft Aortic valve Congenital 52

Journal of Clinical Investigation - Cardiology

FEBRUARY 17, 2025

Lysosomes are implicated in a wide spectrum of human diseases, including monogenic lysosomal storage disorders (LSDs), age-associated neurodegeneration, and cancer. Interestingly, a patient with a milder phenotype and genotype displayed lower accumulation of lysosomal GPDs, consistent with their potential role as disease biomarkers.

Biomarkers 98

Biomarkers Cancer 98

Frontiers in Cardiovascular Medicine

DECEMBER 11, 2024

BackgroundCardiovascular biomarkers are crucial for monitoring cancer therapy-related cardiac toxicity, but the effects on early stage are still inadequate. NT-proBNP levels decreased from baseline to C1 and C5 (P<0.01).

Arrhythmia 52

Arrhythmia Cancer Biomarkers Research 52