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Unhealthy visceral fat is associated with improved efficacy of immunotherapy in endometrial cancer

Journal of Clinical Investigation - Cardiology

Obesity is a known driver of endometrial cancer. Notably, a BMI in the overweight or obese range was paradoxically associated with improved progression-free and overall survival.

Cancer 63
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Evidence-Based Application of Natriuretic Peptides in the Evaluation of Chronic Heart Failure With Preserved Ejection Fraction in the Ambulatory Outpatient Setting

Circulation

Optimal NT-proBNP cut points for HFpEF rule out (optimizing sensitivity) and rule in (optimizing specificity) were derived and tested, stratified by obesity and atrial fibrillation. Current consensus age- and BMI-stratified rule-in thresholds demonstrated only 65% specificity (95% CI, 57%72%).

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Abstract WMP81: Overweight Patients Had Higher Odds of Favorable Outcome After Both Deep and Lobar Intracerebral Hemorrhage

Stroke Journal

Body mass index (BMI) is a widely available marker of nutrition status, however studies on BMI and post-ICH outcomes are limited and have conflicting results. Patients were divided into underweight, normal weight, overweight, and obese according to World Health Organization BMI criteria. 5.94) groups.

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Abstract TP268: Xylitol, Xylose, and MicroRNAs Associated with Thrombosis and the Clotting Cascade in a Multi-Omics Cross-Sectional Study of Adults at Risk for Type 2 Diabetes and Stroke

Stroke Journal

Older adults with obesity and metabolic syndrome may have decreased elimination of the xylitol metabolite xylose, which may explain the higher observed risk of thrombosis and stroke in older adults who consume foods with sugar alcohols. The mean BMI was 35.2 kg/m2, HbA1c was 5.9% 0.4,