Frontiers in Cardiovascular Medicine

MARCH 4, 2024

For cardiovascular disease, only low-density lipoprotein cholesterol and blood pressure are approved as surrogates for cardiovascular disease. For many disease areas, nearly a half of drugs are approved by the U.S. Food & Drug Administration based on beneficial effects on surrogate endpoints.

Plaque 59

Plaque Coronary Artery Disease Blood Pressure Cardiovascular Disease 59

Stroke Journal

FEBRUARY 1, 2024

It is currently unknown if these associations are confounded by pleiotropic effects of the instrumental variables (IV) on cardiovascular disease (CVD) risk factors, such as low-density lipoprotein cholesterol (LDL), diastolic blood pressure (DBP), and body mass index (BMI).

BMI 40

BMI Strokes Stroke Risk Factors 40

Physiologically Speaking

AUGUST 9, 2024

For example, ketogenic diets raise LDL cholesterol, which some people believe is harmful. So rather than investigate how specific nutrients affect health biomarkers, there’s a growing interest in how restricting or supplying these nutrients might affect physical activity and energy expenditure, key factors in overall health.

Physiology 69

Physiology Diet Cholesterol Biomarkers 69

Dr. Paddy Barrett

OCTOBER 31, 2023

They have the biomarker of risk but no evidence of the disease , even later in life when you would expect them to have it. A healthy lifestyle, in this instance, is defined by a combination of: BMI Nutrition Smoking Status Activity Levels Blood Pressure Diabetes Status Cholesterol Levels All of which are highly modifiable.

Coronary Artery Disease 52

Coronary Artery Disease Heart Disease Atherosclerosis Cardiovascular Disease 52

Frontiers in Cardiovascular Medicine

JANUARY 13, 2025

IntroductionThe COVID-19 pandemic, starting in 2020, raised concerns about potential long-term health impacts, including its effects on cardiovascular health and related biomarkers. The study observed modest declines in mean glucose, cholesterol, HDL, and LDL levels post-pandemic, with stable blood pressure.

COVID-19 52

COVID-19 Blood Pressure Cholesterol Biomarkers 52

Dr. Paddy Barrett

APRIL 26, 2024

Coronary artery disease is caused by the retention of a cholesterol particle in the artery wall. But if a retained cholesterol particle is the spark. 1 Association of lipid, inflammatory, and metabolic biomarkers with age at onset for incident coronary heart disease in women. This is the spark that sets the fire.

Heart Disease 105

Heart Disease Coronary Artery Disease Diabetes Genetic predisposition 105

DAIC

JANUARY 23, 2024

1,12,13 While it is important to treat all known risk factors that contribute to ASCVD including high blood pressure, hyperlipidemia, diabetes, and obesity, physicians also need to recognize and treat systemic inflammation in CV disease. 21 Luckily, each of these risks can be measured by simple blood tests.

Cardiovascular Disease 111

Cardiovascular Disease Heart attacks Heart Attack Coronary Artery Disease 111