Circulation: Heart Failure

SEPTEMBER 12, 2023

Fasting blood samples collected at the time of the cardiopulmonary exercise test were used to assay obesity-related biomarkers. Our findings suggest that among the obesity-related biomarkers studied, higher levels of leptin and CRP are independently associated with increased odds of HFpEF, with odds ratios of 1.36 (95% CI, 1.09–1.70)

Biomarkers 40

Biomarkers Obesity Exercise Preserved Ejection Fraction 40

Medical Xpress - Cardiology

JULY 2, 2024

For example, blood pressure changes during exercise (EBP) can reveal a latent tendency toward future development of hypertension. At present, there is no reliable circulating biomarker—a protein or other molecule present in the blood stream—indicative of hypertension risk.

Hypertension 52

Hypertension Blood Pressure Exercise Physiology 52

Frontiers in Cardiovascular Medicine

APRIL 30, 2024

We collected maternal clinical parameters and biomarkers between 16th and 20th weeks of gestation. The HDP group exhibited significantly higher baseline body mass index (BMI), weight change, baseline systolic/diastolic blood pressure, and platelet counts than the control group. 1.17), 1.10 (1.05–1.16), 1.16), 1.04 (1.01–1.08),

Risk Factors 52

Risk Factors Hypertension BMI Blood Pressure 52

Dr. Paddy Barrett

APRIL 12, 2024

Less high blood pressure. 2 [link] 3 Physical activity patterns and biomarkers of cardiovascular disease risk in hunter-gatherers. 6 Sitting Time Reduction and Blood Pressure in Older Adults: A Randomized Clinical Trial. Higher step counts are a reliable way of hitting this goal. Less obstructive sleep apnea.

Quality of Life 124

Quality of Life Blood Pressure Exercise Chronic Disease 124

Open Heart

JANUARY 19, 2022

We measured the development in cardiac power output (CPO), stroke work (SW), aortic elastance, microcirculatory metabolism, inflammatory and cardiac biomarkers and need for vasoactive medications. to 0.96), while inflammatory biomarkers and other cardiac biomarkers did not predict the duration of vasoactive pressure support.

Cardiac Arrest 52

Cardiac Arrest Hospital Biomarkers Blood Pressure 52

Frontiers in Cardiovascular Medicine

FEBRUARY 7, 2024

It is characterized by asymptomatic elevations in blood pressure beyond normal levels but not yet reaching the threshold for hypertension. Conclusion These findings suggest possible biomarkers that can predict the risk of progression from pre-hypertension to hypertension.

Hypertension 64

Hypertension Blood Pressure Biomarkers Heart Disease 64

Frontiers in Cardiovascular Medicine

FEBRUARY 18, 2025

Abnormal stress biomarkers [regional wall motion abnormalities (RWMAs), ST-segment depression, induced angina, peak systolic blood pressure, force-based contractile reserve (CR), heart rate reserve (HRR), and low exercise capacity] were used for phenotyping.

Chest Pain 52

Chest Pain Exercise Angina Coronary Artery Disease 52

Hypertension Journal

JANUARY 2, 2024

Approximately 50% of hypertensive and 25% of normotensive people exhibit salt sensitivity of blood pressure, which is an independent risk factor for cardiovascular disease. Antigen-presenting and adaptive immune cells are implicated in salt-sensitive hypertension and salt-induced renal and vascular injury.

Hypertension 40

Hypertension Blood Pressure Cerebrovascular Disease Risk Factors 40

DAIC

MARCH 25, 2025

25 include Efficacy and safety of finerenone across the spectrum of kidney risk in heart failure with mildly reduced or preserved ejection fraction during the session;"Innovations and Insights in Heart Failure With Preserved Ejection Fraction: Emerging Therapies, Biomarkers and Mechanistic Studies."

Preserved Ejection Fraction 52

Preserved Ejection Fraction Heart Failure Research Academic 52

Hypertension Journal

DECEMBER 11, 2024

The magnitude of renin-independent aldosterone production was defined via using tertiles of 24-hour urinary aldosterone production during the oral sodium suppression test to create unbiased categorizations of the magnitude of PA.

Blood Pressure 40

Blood Pressure Biomarkers Hypertension 40

Circulation: Heart Failure

MARCH 5, 2025

EIH was defined as systolic blood pressure (BP) at peak exercise >210 mm Hg in men or >190 mm Hg in women.RESULTS:In this prospective cohort study, we assessed patients with COA (n=41, age 4314 years, 26 [63%] men) and healthy controls (n=41).

Exercise 40

Exercise Hypertension Outcomes Biomarkers 40

Frontiers in Cardiovascular Medicine

MARCH 4, 2024

For cardiovascular disease, only low-density lipoprotein cholesterol and blood pressure are approved as surrogates for cardiovascular disease. For many disease areas, nearly a half of drugs are approved by the U.S. Food & Drug Administration based on beneficial effects on surrogate endpoints.

Plaque 59

Plaque Coronary Artery Disease Blood Pressure Cardiovascular Disease 59

Stroke Journal

JANUARY 30, 2025

Patients with increasing CT-CSVD scores were older (p<0.001), more likely to have hypertension (p<0.001), diabetes (p<0.001), coronary artery disease (p=0.044), and a higher baseline systolic blood pressure (p=0.037). 1.02; score 2: OR 0.46, 95%CI 0.26-0.83; 0.83; score 3: OR 0.16, 95%CI 0.03-0.76,

Thrombolysis 40

Thrombolysis Outcomes Biomarkers Strokes 40

Dr. Paddy Barrett

SEPTEMBER 13, 2024

High Blood Pressure. Elevated Blood Glucose. I'm Interested In Case You Missed Them: 1 Association of lipid, inflammatory, and metabolic biomarkers with age at onset for incident coronary heart disease in women. On the continuum of insulin resistance before the appearance of type 2 diabetes is metabolic syndrome.

Risk Factors 105

Risk Factors Heart Disease Dementia Diabetes 105

The British Journal of Cardiology

JUNE 11, 2024

Additionally, 2D transthoracic echocardiography (TTE), and myocardial injury serum biomarkers assays (creatine phosphokinase-MB [CPK-MB] and cardiac troponins [cTn]) were measured once. New-onset high systolic and diastolic blood pressures were seen in 67 patients (10%).

COVID-19 40

COVID-19 Cardiovascular Disease Angina Chest Pain 40

Dr. Paddy Barrett

APRIL 26, 2024

Not smoking Being physically active Good nutrition Achieving target HBA1c levels Normal weight Normal blood pressure Normal total cholesterol Whether or not a person with type 2 diabetes hits any or all of these metrics matters a lot. Seven Factors Let’s look at seven separate healthy factors.

Heart Disease 104

Heart Disease Coronary Artery Disease Diabetes Genetic predisposition 104

Dr. Smith's ECG Blog

DECEMBER 11, 2023

Her systolic blood pressure at the dentist was over 200 mm Hg. She was given nitroglycerin which improved her blood pressure, and she completed the procedure. The neighbor recorded a systolic blood pressure again above 200 mm Hg and advised her to come to the ED to address her symptoms. Her arm pain abated.

Myocardial Infarction 123

Myocardial Infarction Chest Pain STEMI Blood Pressure 123

GEMMS

MAY 22, 2024

Traditional tools like stethoscopes, blood pressure gauges, and electrocardiograms (ECG) are fundamental for standard diagnostic practices. Innovative algorithms analyze gene biomarkers to provide predictive insights and personalized patient therapy.

Heart Disease 52

Heart Disease Blood Pressure Technology Innovation 52

Hypertension Journal

SEPTEMBER 21, 2023

Recently, some randomized trials, including the SPRINT (Systolic Blood Pressure Intervention Trial), have suggested that improvements in cardiovascular risk factors may also slow cognitive decline and reduce the eventual development of dementia.

Dementia 40

Dementia Cardiovascular Interventions Blood Pressure Physiology 40

Stroke Journal

JANUARY 30, 2025

Glial fibrillary acidic protein (GFAP) is a highly promising blood biomarker indicating ICH. This opens the potential for optimized triage as well as the initiation of blood pressure lowering therapy and anticoagulation reversal in earlier time frames.

Hemorrhage 40

Hemorrhage Strokes Stroke Blood Pressure 40

Circulation

DECEMBER 22, 2023

Dietary interventions are an effective approach to lower blood pressure (BP) but are not equally effective across all individuals. BACKGROUND:Hypertension is a key risk factor for major adverse cardiovascular events but remains difficult to treat in many individuals.

Hypertension 45

Hypertension Blood Pressure Biomarkers Risk Factors 45

Journal of the American Heart Association

FEBRUARY 14, 2024

BackgroundThe renal sympathetic nervous system modulates systemic blood pressure, cardiac performance, and renal function. In addition, renal injury, oxidative stress, inflammation, and profibrotic biomarkers were evaluated to determine pathways associated with RDN. Journal of the American Heart Association, Ahead of Print.

Preserved Ejection Fraction 40

Preserved Ejection Fraction Heart Failure Blood Pressure Biomarkers 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Further studies are required to clarify the utility of this biomarker in guiding post‐EVT care.

Strokes 40

Strokes Stroke Blood Pressure Document 40

Stroke Journal

FEBRUARY 1, 2024

Other significant risk markers included systolic blood pressure, hypertension, estimated glomerular filtration rate, metabolic syndrome, and blood sugar level. This study presents a data-driven machine-learning framework for stroke risk prediction and biomarker identification.

Strokes 40

Strokes Stroke Blood Pressure Laboratory 40

Stroke Journal

FEBRUARY 1, 2024

It is currently unknown if these associations are confounded by pleiotropic effects of the instrumental variables (IV) on cardiovascular disease (CVD) risk factors, such as low-density lipoprotein cholesterol (LDL), diastolic blood pressure (DBP), and body mass index (BMI).

BMI 40

BMI Risk Factors Strokes Stroke 40

DAIC

JANUARY 23, 2024

1,12,13 While it is important to treat all known risk factors that contribute to ASCVD including high blood pressure, hyperlipidemia, diabetes, and obesity, physicians also need to recognize and treat systemic inflammation in CV disease. An hsCRP test is more sensitive and can find smaller increases in CRP than a standard test can.23

Cardiovascular Disease 111

Cardiovascular Disease Heart Attack Heart attacks Coronary Artery Disease 111

Physiologically Speaking

AUGUST 9, 2024

So rather than investigate how specific nutrients affect health biomarkers, there’s a growing interest in how restricting or supplying these nutrients might affect physical activity and energy expenditure, key factors in overall health. It’s also important to acknowledge that each of us respond to nutrients and food differently.

Physiology 69

Physiology Diet Cholesterol Biomarkers 69

Dr. Paddy Barrett

OCTOBER 31, 2023

They have the biomarker of risk but no evidence of the disease , even later in life when you would expect them to have it. A healthy lifestyle, in this instance, is defined by a combination of: BMI Nutrition Smoking Status Activity Levels Blood Pressure Diabetes Status Cholesterol Levels All of which are highly modifiable.

Coronary Artery Disease 52

Coronary Artery Disease Heart Disease Atherosclerosis Cardiovascular Disease 52

Dr. Smith's ECG Blog

DECEMBER 14, 2016

The blood pressure was 110/60. less than 2 h from hospital admission, analogous to STEMI management) invasive strategy with intent to perform revascularization is recommended, irrespective of ECG or biomarker findings. It was not relieved by anything. The pain was not positional, pleuritic, or reproducible. This includes: 1.

Chest Pain 52

Chest Pain STEMI Aortic Myocardial Infarction 52

Physiologically Speaking

MARCH 29, 2024

In a new study, evening exercise, but not morning exercise, reduced blood pressure, lowered sympathetic activity, and improved baroreflex sensitivity in a group of adults with treated hypertension. VO 2 max), body composition, and diastolic blood pressure. Circadian Clock-Mediated Regulation of Blood Pressure - PMC.

Blood Pressure 52

Blood Pressure Exercise Physiology Hypertension 52

Frontiers in Cardiovascular Medicine

JANUARY 13, 2025

IntroductionThe COVID-19 pandemic, starting in 2020, raised concerns about potential long-term health impacts, including its effects on cardiovascular health and related biomarkers. The study observed modest declines in mean glucose, cholesterol, HDL, and LDL levels post-pandemic, with stable blood pressure.

COVID-19 52

COVID-19 Blood Pressure Cholesterol Biomarkers 52

Journal of the American Heart Association

FEBRUARY 14, 2024

Different blood pressure phenotypes including categorical (responder versus nonresponder) and continuous diastolic blood pressure and systolic blood pressure were tested for association with the candidate miRNA expression using multivariate regression analyses adjusting for age, sex, and baseline blood pressure.

Biomarkers 45

Biomarkers Circulation Hypertension Blood Pressure 45

Stroke Journal

FEBRUARY 1, 2024

Neurodegenerative plasma biomarkers may be associated with cognitive decline via vascular processes causing higher WMHv such as cerebral amyloid angiopathy & inflammatory small vessel disease. Conclusion:There were no significant adjusted associations between any plasma biomarker with CR.

Blood Pressure 40

Blood Pressure Biomarkers Education Hypertension 40

Open Heart

AUGUST 16, 2023

Objective To characterise cardiac remodelling, exercise capacity and fibroinflammatory biomarkers in patients with aortic stenosis (AS) with and without diabetes, and assess the impact of diabetes on outcomes. Results Diabetes (n=56) and non-diabetes groups (n=198) were well matched for age, sex, ethnicity, blood pressure and severity of AS.

Exercise 52

Exercise Diabetes Stenosis Aortic 52

Physiologically Speaking

APRIL 24, 2024

The amount of calcium in the blood vessels (known as arterial calcification), a marker of subclinical atherosclerosis, is higher in people with a short sleep duration. Multiple studies find that the risk for high blood pressure (hypertension) is elevated in women with short sleep duration to a greater extent than it is in men.

Blood Pressure 52

Blood Pressure Blood Clot COVID-19 Cardiovascular Disease 52

Stroke Journal

FEBRUARY 1, 2024

Due to conflicting prior studies, it is uncertain if the degree of systolic blood pressure reduction increases the risk. Patients with severe, chronic hypertension may be more vulnerable to the development of ischemia after ICH due to altered cerebral autoregulatory limits. and LVH was seen in 23.5%.

Hemorrhage 40

Hemorrhage Blood Pressure Hypertension Biomarkers 40

Journal of the American Heart Association

DECEMBER 29, 2023

Plasma calprotectin levels were studied for associations with the risk of new‐onset hypertension, defined as systolic blood pressure of at least 140 mm Hg, diastolic blood pressure of at least 90 mm Hg, or the first recorded use of antihypertensives. 0.66) mg/L, and median systolic blood pressure was 117 (109–126) mm Hg.

Hypertension 40

Hypertension Blood Pressure Biomarkers 40