Med Page Today

MARCH 6, 2024

(MedPage Today) -- DENVER -- People with HIV who received semaglutide (Ozempic, Wegovy) had reduced levels of several inflammatory biomarkers associated with cardiovascular disease, a randomized controlled trial showed. After 32 weeks, interleukin.

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Biomarkers Cardiovascular Disease 111

HCPLive

JUNE 10, 2024

Strnad explains key findings from research presented at the EASL Congress regarding noninvasive testing and biomarkers in AATD-LD based on phase 2 fazirsiran clinical trials.

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Biomarkers Research 98

HCPLive

AUGUST 22, 2024

These data on systemic inflammatory biomarkers for patients with eczema may allow for more targeted treatments and for greater personalization of medicine for this skin condition.

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Biomarkers 75

DAIC

APRIL 22, 2024

This is an innovative platform for measuring biomarkers,” stated Dr. Karlsberg. This study highlights the value of digital biomarkers that may enable instantaneous feedback for care providers in assessing the patient. milla1cf Mon, 04/22/2024 - 15:05 April 22, 2024 — At the annual American College of Cardiology conference ( ACC.24

Technology 105

Technology Biomarkers Heart attacks Heart Attack 105

JAMA Cardiology

APRIL 5, 2024

This cohort study explores whether a novel artificial intelligence (AI) video-based biomarker for aortic stenosis is associated with development and progression of aortic stenosis.

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Biomarkers Stenosis Aortic 94

American College of Cardiology

OCTOBER 9, 2024

What is the value of specific biomarkers for heart failure (HF) risk stratification in patients with atrial fibrillation (AF)?

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Biomarkers Atrial Fibrillation Heart Failure Article 60

Medical Xpress - Cardiology

JANUARY 25, 2024

An international academic consortium has identified 13 biomarkers that significantly improve the ability to accurately predict cardiovascular disease risk in people with type 2 diabetes.

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Biomarkers Cardiovascular Disease Diabetes Academic 127

Nature Reviews - Cardiology

JULY 21, 2024

Nature Reviews Cardiology, Published online: 22 July 2024; doi:10.1038/s41569-024-01060-8 In this Roadmap arising from an NHLBI workshop, Chew and colleagues explore the use of retinal imaging biomarkers for the prediction, diagnosis and monitoring of systemic cardiovascular diseases.

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Biomarkers Cardiovascular Disease Research 75

Science Daily - Heart Disease

MARCH 18, 2024

Researchers have identified novel protein biomarkers that are associated with the development of CHD in people with and without diabetes. Coronary heart disease is a major global health problem, especially among people with type 2 diabetes.

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Biomarkers Heart Disease Diabetes Research 73

HCPLive

SEPTEMBER 25, 2024

Findings from the prospective cohort study suggest the value of serum Z polymer levels as a non-invasive disease-specific biomarker in patients with homozygous ZZ AATD liver disease.

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Biomarkers 52

Circulation

NOVEMBER 11, 2024

In this study, we proposed and employed a novel approach combining traditional statistics and a nexus of cutting-edge AI/ML techniques to identify significant biomarkers for our predictive engine by analyzing the complete transcriptome of CVD patients (Figure 1).

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Biomarkers Cardiovascular Disease Circulation 40

Heart BMJ

SEPTEMBER 16, 2024

In this setting, circulating biomarkers, a component of the liquid biopsy, provide a promising approach for the fast, affordable and scalable screening of large numbers of patients, allowing the detection of different pathological features related to myocardial remodelling, aiding in risk stratification and therapy monitoring.

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Biomarkers Circulation 52

American College of Cardiology

OCTOBER 16, 2024

He then explores an analysis from COMBINE-AF on heart failure (HF) risk assessment using biomarkers in patients with atrial fibrillation. Eagle looks at an individual patient data meta-analysis of semaglutide and blood pressure (BP).

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Biomarkers Blood Pressure Atrial Fibrillation Stent 56

Journal of the American Heart Association

FEBRUARY 27, 2024

A group of 24 candidate biomarkers supported by prior literature was assessed at baseline and 24 weeks later. Longitudinal analyses examined the association between baseline biomarker values, measured in plasma EDTA, and the change in arterial inflammation target to background ratio. to 0.33 (likelihood ratioP=0.0005).ConclusionsA

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Biomarkers 74

Cardiovascular Diabetology

NOVEMBER 1, 2024

Dysglycemia and insulin resistance increase type 2 diabetes (T2D) and cardiovascular disease (CVD) risk, yet associations with specific glucose-insulin homeostatic biomarkers have been inconsistent. Vitamin D.

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Biomarkers Cardiovascular Disease Diabetes Research 52

Medical Xpress - Cardiology

JANUARY 31, 2024

A collaborative cohort of researchers, led by University of Colorado Anschutz Medical Campus professor Angelo D'Alessandro, has identified kynurenine as a critical new biomarker in the quality of stored red blood cells (RBCs), a crucial step in the development of more personalized transfusions.

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Biomarkers Research 72

Frontiers in Cardiovascular Medicine

JANUARY 31, 2024

Objective In patients with complex coronary artery disease (CAD) undergoing cardiac surgery, myocardial protection might be impaired due to microvascular obstruction, resulting in myocardial injury and subsequent biomarker release. Preoperatively, higher levels of cardiac biomarkers were found in patients with higher SYNTAX Score II.

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Coronary Artery Disease Biomarkers Outcomes 64

Medical Xpress - Cardiology

MARCH 18, 2024

The research team investigated the predictive performance of protein biomarkers on incident CHD in individuals with and without T2D. Among middle-aged adults, individuals with type 2 diabetes (T2D) have a two to four times higher risk of developing CHD than people without T2D.

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Biomarkers Heart Disease Diabetes Research 62

HCPLive

JUNE 5, 2024

The key opinion leaders explore the utilization of biomarkers in guiding the treatment of severe or uncontrolled asthma, discussing the specific role of eosinophils in informing therapeutic decision-making for patients with challenging asthma cases.

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Biomarkers 52

HCPLive

AUGUST 16, 2024

Strnad explains the need for noninvasive biomarkers in AATD liver disease and early research about circulating Z-polymer’s potential association with clinically relevant adverse outcomes.

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Biomarkers Circulation Research Outcomes 52

Circulation

NOVEMBER 11, 2024

Exploring potential biomarkers from mitochondrial perspective may be effective in the diagnosis and treatment of PAH. Then, the potential biomarkers for PAH were accessed by single-cell data analysis, drug prediction, miRNA-transcription factor-mRNA network construction, and receiver operating characteristic curves.

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Biomarkers Pulmonary Hypertension Circulation 40

Journal of Clinical Investigation - Cardiology

APRIL 1, 2024

There is unmet need for additional biomarkers to better select patients with non–small cell lung cancer (NSCLC) that are likely to benefit from immunotherapy in order to improve patient outcomes, reduce patient toxicity, and relieve the growing burden of healthcare costs.

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Biomarkers Cancer Outcomes 75

Society of Thoracic Surgeons - Surgeon

NOVEMBER 16, 2023

Webinar Biomarker Testing and Neoadjuvant Immunotherapy for Resectable NSCLC dkaczmarek Thu, 11/16/2023 - 16:01 December 14, 2023 Part 2 of a 2-part webinar series, supported by AstraZeneca This webinar will address preoperative biomarker testing and issues around neoadjuvant immunotherapy for NSCLC. Moderators Robert E.

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Biomarkers Webinar 52

Nature Reviews - Cardiology

MARCH 17, 2024

In this Review, Caporali and colleagues examine the biology of these molecules and discuss the potential of non-coding RNAs for translation to the clinic as biomarkers and therapeutics in adverse cardiac remodelling leading to ischaemic heart failure.

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Biomarkers Heart Disease Heart Failure 72

HCPLive

JANUARY 23, 2024

Wesley Mizutani, MD, discusses California's SB 496 legislation, which addresses the crucial role of biomarkers in guiding optimal drug selection to improve overall healthcare outcomes.

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Biomarkers Outcomes 59

Stroke Journal

MARCH 24, 2024

While researchers in the Alzheimer disease field have been working for years to establish and test blood-based biomarkers for Alzheimer disease diagnosis, prognosis, clinical therapy discovery, and early detection, blood-based biomarkers for VCID are in their infancy and also face challenges.

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Biomarkers Dementia Hemorrhage Research 40

Frontiers in Cardiovascular Medicine

JULY 17, 2024

This study employs bioinformatics approaches to identify common biomarkers and pathways between AS and ankylosing spondylitis.MethodsGene expression datasets for AS (GSE100927, GSE28829, GSE155512) and ankylosing spondylitis (GSE73754, GSE25101) were obtained from the Gene Expression Omnibus (GEO).

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Biomarkers Atherosclerosis 64

Heart BMJ

MAY 10, 2024

Biomarkers have dramatically impacted the way patients with HF are evaluated and managed. The most studied biomarkers in HF are natriuretic peptides (NPs). A timely diagnosis and initiation of evidence-based treatments are key to prevent hospitalisation and improve outcomes in this population.

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Biomarkers Heart Failure Physiology Article 52

Frontiers in Cardiovascular Medicine

MARCH 3, 2024

The goal of our study is to identify potential relationships between plasma biomarkers and cardiac magnetic resonance (CMR) imaging markers in patients with HFpEF. Partial least squares discriminant analysis (PLS-DA) was used to characterize CMR and biomarker variables that differentiate the subject groups into two principal components.

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Preserved Ejection Fraction Biomarkers Heart Failure 64

Society of Thoracic Surgeons - Surgeon

MAY 23, 2024

Video 8 in 8: Biomarker Testing and Neoadjuvant Immunotherapy for Resectable NSCLC kchalko Thu, 05/23/2024 - 09:56 In this video in the 8 in 8 Series, Dr. Dwight Owen (Ohio State University) discussed advances in biomarker testing and neoadjuvant immunotherapy for resectable non-small cell lung cancer.

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Biomarkers CME Cardiothoracic Cancer 52

JAMA Cardiology

FEBRUARY 20, 2024

This substudy of a randomized clinical trial investigates the effects of pitavastatin on noncalcified coronary artery plaque using coronary computed tomography angiography and on inflammatory biomarkers as potential mechanisms for major adverse cardiovascular event prevention.

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Coronary Artery Disease Biomarkers Plaque 72

HCPLive

FEBRUARY 28, 2024

A study from Brigham and Women's Hospital has identified 6 blood-based biomarkers that may predict cardiovascular disease risk in rheumatoid arthritis patients.

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Biomarkers Cardiovascular Disease Hospital 59

Frontiers in Cardiovascular Medicine

AUGUST 11, 2024

The objectives of our study were to identify potential biomarkers for PV-related AS and to explore the molecular biological association between PV and AS.MethodsWe extracted microarray datasets from the Gene Expression Omnibus (GEO) dataset for PV and AS. The expression of potential biomarkers was validated using an external dataset.

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Biomarkers Atherosclerosis Thrombosis 52

HCPLive

FEBRUARY 19, 2024

In this Lungcast segment, Spicer spoke on several treatment-specific biomarkers for lung cancer and discussed the future of lung cancer therapy.

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Biomarkers Cancer Research 69

Science Daily - Heart Disease

JANUARY 11, 2024

Scientists have found that two common biomarkers could predict cardiomyopathy that is otherwise undetected by conventional screenings in childhood cancer survivors.

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Biomarkers Cancer Cardiomyopathy 58

Medical Xpress - Cardiology

SEPTEMBER 2, 2024

Low concentrations of three selected biomarkers in the blood of patients with atrial fibrillation identify patients with a high chance of attaining sinus rhythm. This is the main result of this analysis of the EAST—AFNET 4 biomolecule study.

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Atrial Fibrillation Biomarkers 40

HCPLive

MAY 31, 2024

Using available literature, the review assesses our current understanding of AATD, emerging biomarkers, and the future of drug development.

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Biomarkers 52