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Circulation: Cardiovascular Interventions, Ahead of Print. BACKGROUND:Transcatheter edge-to-edge mitral valve (MV) repair (TEER) is an effective treatment for patients with primary mitral regurgitation at prohibitive risk for surgical MV repair (MVr).
Circulation: Cardiovascular Interventions, Ahead of Print. BACKGROUND:Data concerning the outcomes of transcatheter aortic valve replacement in type 0 bicuspid aortic stenosis (AS) are scarce. Ascending aortic diameter was the single predictor of 1-year mortality in type 0 bicuspid patients (hazard ratio, 1.59 [95% CI, 1.03–2.44];P=0.035).
Circulation, Ahead of Print. We focus on the most common primary valvular heart diseases, including calcific aortic stenosis, bicuspid aortic valves, mitral valve prolapse, and rheumatic heart disease, and outline the fundamental molecular discoveries contributing to each.
Left atrium (LA) is far from simply being a passive connection chamber between left ventricle and the pulmonary circulation. In patients affected by mitral regurgitation (MR) an impairment in LA compliance and.
Circulation: Cardiovascular Interventions, Ahead of Print. BACKGROUND:Many patients with atrial functional mitral regurgitation are not suitable candidates for surgery or transcatheter repair. Technical success and mitral regurgitation reduction from severe to none/trace were achieved in all cases.
Circulation, Volume 150, Issue Suppl_1 , Page A4138007-A4138007, November 12, 2024. Introduction:Fabry disease, caused by mutations in the gene encoding alpha-galactosidase A, results in the accumulation of globotriaosylceramide (Gb3), leading to systemic complications including cardiac involvement such as mitral regurgitation (MR).The
Circulation, Volume 150, Issue Suppl_1 , Page A4144768-A4144768, November 12, 2024. Enhanced TGFβ signaling induced byFbn1mutation is a major contributor to the MFS pathogenesis, one of which is myxomatous mitral valve degeneration that can cause mitral valve prolapse, with an incidence of about 45% inFBN1mutant individuals.
Circulation, Ahead of Print. Pathogeneses include connective tissue disorders, smooth muscle contraction disorders, and congenital heart disease, including bicuspid aortic valve, among others. Aortopathy encompasses a spectrum of conditions predisposing to dilation, aneurysm, dissection, or rupture of the aorta and other blood vessels.
Circulation: Cardiovascular Interventions, Ahead of Print. BACKGROUND:Limited data exist regarding the impact of mitral annular calcification (MAC) on outcomes of transcatheter edge-to-edge repair for mitral regurgitation (MR).METHODS:We with functional MR) who underwent an isolated, first-time intervention.
Circulation, Volume 150, Issue Suppl_1 , Page A4145373-A4145373, November 12, 2024. Background:There have been several studies postulating the association between Mitral valve stenosis (MS) and Chronic Kidney Disease (CKD). The prevalence of non rheumatic Mitral stenosis (MS) in the admission cohort was analyzed.
RLS-ESUS showed higher frequency of anterior circulation lesion (RLS-ESUS vs. non RLS-ESUS; 84% vs. 71%, p = 0.035), slower early mitral inflow velocity (E) (51.6 0.99, p = 0.037) and anterior circulation lesion (OR 2.23, 95%CI 1.08-4.62, 0.99, p = 0.037) and anterior circulation lesion (OR 2.23, 95%CI 1.08-4.62,
Circulation, Ahead of Print. BACKGROUND:A better understanding of the molecular mechanism of aortic valve development and bicuspid aortic valve (BAV) formation would significantly improve and optimize the therapeutic strategy for BAV treatment.
Circulation, Volume 150, Issue Suppl_1 , Page A4117438-A4117438, November 12, 2024. Introduction:Transcatheter Mitral Valve Edge to Edge Repair (TEER) is an established percutaneous treatment for patients with severe symptomatic Mitral Regurgitation (MR).
Circulation: Cardiovascular Imaging, Ahead of Print. Severe mitral regurgitation (MR) also causes a low-flow state, adding complexity to diagnosis and management.
Circulation: Cardiovascular Imaging, Ahead of Print. BACKGROUND:Patients with only moderate atrial secondary mitral regurgitation (asMR) frequently develop heart failure (HF). Although mild/moderate primary mitral regurgitation is compensated by left ventricular (LV) dilatation, the LV is not dilated in asMR.
Despite its high prevalence, effective treatment for degenerative mitral regurgitation (MR) remains elusive. Mechanistically, combination therapy effectively suppressed circulating and cardiac expression of aldosterone- and apoptosis-associated proteins.
The minimally invasive extracorporeal circulation (MiECC) system was developed to minimize the contact of blood with air and foreign surfaces during conventional cardiopulmonary bypass (CPB). It is also aimed.
However, underlying lesions such as hypertension, mitral valve disease, COPD, ASD, and TR greatly influence the degree of atrial enlargement. This is similar to MR begets MR. Atrial functional MR occurs when the lower part of the atria stretches the mitral annulus. We know atrial flutters can be confined to one atrium.
Circulation, Volume 150, Issue Suppl_1 , Page A4144084-A4144084, November 12, 2024. It is primarily indicated for refractory angina that is not amenable to PCI or CABG with the opinion of a cardiologist.
Transcript of video: Hypoplastic Left Heart Syndrome is a very severe form of congenital heart disease, in which, the left ventricle, aorta and mitral and aortic valves are hypoplastic and valves may be atretic as well. A Gore-Tex tube is used and this maintains, this is a Blalock-Taussig shunt, which maintains pulmonary circulation.
Though there are several parameters for evaluation of left ventricular diastolic function by echocardiography, the most commonly used are the pulsed Doppler mitral E/A ratio and tissue Doppler mitral E/e’ ratio. Doppler interrogation of mitral valve is usually done from the apex through the apical four chamber view.
His research centers on the comprehensive management of patients post-TAVR, transcatheter mitral and tricuspid valve interventions, and advanced imaging techniques in structural heart disease.
Circulation: Cardiovascular Interventions, Volume 18, Issue 3 , Page e014819, March 1, 2025. Patients were grouped by the mechanism of mitral regurgitation (MR) and divided into time periods.RESULTS:Overall, 68 028 patients were included. Patients in shock were excluded.
The Mustard procedure is an atrial switch operation baffling the systemic venous flow to the mitral valve and the pulmonary venous flow to the tricuspid valve to restore sequential pulmonary and systemic circulation.
At night, when one is lying down, extra fluid from the legs gets absorbed into the circulation and gets redistributed into the lungs, which is at a lower position compared to day time (lungs being in the upper part of the body, gets less fluid logged in sitting and standing position).
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