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Asymptomatic severe degenerative mitral regurgitation

Heart BMJ

Degenerative mitral valve disease is common. Up to a quarter of patients with degenerative mitral valve disease may be asymptomatic despite having severe valve regurgitation. Efforts should focus on establishing high-volume regional centres of excellence for mitral valve repair.

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Management of bicuspid aortic valve disease in the transcatheter aortic valve implantation era

Heart BMJ

In an era of rapidly expanding use of transcatheter aortic valve implantation (TAVI), the management of patients with bicuspid aortic valve (BAV) disease is far less well established than in those with trileaflet anatomy.

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Contribution of rare chromosome 22q11.2 copy number variants to non-syndromic bicuspid aortic valve

Heart BMJ

Background Bicuspid aortic valve (BAV) is the most common congenital heart defect in adults, often leading to complications such as thoracic aortic aneurysms and aortic stenosis. While BAV is frequently associated with 22q11.2

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Rare genetic variants linked to bicuspid aortic valve disease in young adults identified

Medical Xpress - Cardiology

Genetic variants linked to a rare form of bicuspid aortic valve disease that affects young adults and can lead to dangerous and potentially life-threatening aortic complications have been identified by researchers at UTHealth Houston.

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Aortic valve replacement in a bicuspid aortic valve patient followed by reoperation for ascending aorta rupture: a case report

Frontiers in Cardiovascular Medicine

Bicuspid aortic valve (BAV), the most common congenital cardiac anomaly, predisposes individuals to aortic stenosis and regurgitation due to valve degeneration. Abnormal hemodynamics, arterial wall characteristics, and genetic factors contribute to ascending aorta dilatation, potentially leading to severe complications like aortic dissection.

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Columbia Cardiology Launches New Mitral & Tricuspid Center

DAIC

Columbia University Irving Medical Center’s Division of Cardiology has announced its launch of the Mitral & Tricuspid Center. Tricuspid and mitral valves are debilitating conditions that can lead to arrhythmias, hypertension, and heart failure.

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Transcatheter Edge‐to‐Edge Repair for Severe Mitral Regurgitation in Patients With Cardiogenic Shock: A Systematic Review and Meta‐Analysis

Journal of the American Heart Association

BackgroundPatients with severe mitral regurgitation and cardiogenic shock demonstrate a poor prognosis. Device success was achieved in 86% (95% CI, 85%87%) and mitral regurgitation 2+ in 89% (95% CI: 88%90%). A total of 24 studies and 5428 patients were included, with a mean age of 71.23.3