Does Screening for Atrial Fibrillation Reduce Stroke Risk?
NEJM Journal Watch - Cardiology
SEPTEMBER 30, 2024
A 14-day monitor detected more atrial fibrillation but did not affect hospitalization rates for stroke or hemorrhage.
Blinded Randomized trial of Anticoagulation to prevent Ischemic stroke and Neurocognitive impairment in Atrial Fibrillation
American College of Cardiology
NOVEMBER 16, 2024
The goal of the BRAIN-AF trial was to evaluate the impact of rivaroxaban compared with placebo on preventing cognitive decline, stroke, or TIA among patients with atrial fibrillation (AF).
Early Treatment of Atrial Fibrillation for Stroke Prevention Trial
American College of Cardiology
OCTOBER 11, 2024
The goal of the EAST-AFNET 4 trial was to compare a rhythm-control strategy vs. usual care (rate control in the majority of cases) among patients with a recent diagnosis of atrial fibrillation (AF).
Heart failure, atrial fibrillation and coronary heart disease linked to cognitive impairment
Medical Xpress - Cardiology
OCTOBER 10, 2024
Three common cardiovascular diseases in adults—heart failure, atrial fibrillation and coronary heart disease—are linked to cognitive impairment and increased risk of dementia, according to "Cardiac Contributions to Brain Health," a new scientific statement from the American Heart Association published today in the journal, Stroke.
Five facts about atrial fibrillation
Medical Xpress - Cardiology
SEPTEMBER 13, 2024
Atrial fibrillation, or AFib, is a fast and irregular heart rhythm that, left untreated, can lead to blood clots, stroke and heart failure. It's the most common type of arrhythmia, a potentially serious condition in which the heart beats too quickly, too slowly or in an irregular pattern.
Tiny deletion in heart muscle protein linked to long-term effects on adult atrial fibrillation
Medical Xpress - Cardiology
JULY 25, 2024
Millions of adults have atrial fibrillation—an irregular beating of the upper chambers of the heart that yields increased risk of heart failure, stroke and death.
Does Fish Oil Supplement Increase Risk of Stroke and Atrial Fibrillation?
All About Cardiovascular System and Disorders
MAY 23, 2024
The authors reported that the regular use of fish oil supplements might be a risk factor for atrial fibrillation among general population. In their study healthy stage was considered as primary stage, occurrence of atrial fibrillation as secondary stage, major adverse cardiovascular events tertiary stage and death as end stage.
Stroke Survivors With Afib Could Start DOACs Earlier
Med Page Today
OCTOBER 25, 2024
(MedPage Today) -- It was safe to start direct oral anticoagulant (DOAC) therapy without delay after acute ischemic stroke in people with atrial fibrillation (Afib), according to the OPTIMAS randomized trial. Stroke survivors randomized to early.
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Which risk factors are linked to having a severe stroke?
Science Daily - Heart Disease
NOVEMBER 13, 2024
People with conditions or habits such as high blood pressure, an irregular heartbeat called atrial fibrillation, or smoking, not only have a higher risk of stroke, they may also have more severe strokes than people without these risk factors.
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Artificial intelligence predicts undiagnosed atrial fibrillation in patients with embolic stroke of undetermined source using sinus rhythm electrocardiograms
HeartRhythm
MARCH 14, 2024
Artificial intelligence (AI)-enabled sinus rhythm (SR) electrocardiogram (ECG) interpretation can aid in identifying undiagnosed paroxysmal atrial fibrillation (AF) in patients with embolic stroke of undetermined source (ESUS).
Optimal timing of oral anticoagulation initiation in patients with acute ischaemic stroke and atrial fibrillation: a comprehensive meta-analysis and systematic review
Open Heart
NOVEMBER 27, 2024
The optimal timing for initiating direct oral anticoagulants (DOACs) for secondary stroke prevention in patients with atrial fibrillation and acute ischaemic stroke remains controversial due to concerns about haemorrhagic transformation. The early DOAC group (mean initiation 3.5±1.29 days) had 6770 participants.
Association between catheter ablation of atrial fibrillation and mortality or stroke
Heart BMJ
JANUARY 10, 2024
Objective Catheter ablation of atrial fibrillation effectively reduces symptomatic burden. However, its long-term effect on mortality and stroke is unclear. We investigated if patients with atrial fibrillation who undergo catheter ablation have lower risk for all-cause mortality or stroke than patients who are managed medically.
PO-03-084 GENETIC PREDISPOSITION TO ATRIAL FIBRILLATION INCREASES ISCHEMIC STROKE RISK AMONG INDIVIDUALS WITH ATRIAL FIBRILLATION
HeartRhythm
APRIL 30, 2024
Atrial fibrillation is the most prevalent sustained cardiac arrhythmia and an important risk factor for ischemic stroke resulting in a fivefold increased stroke risk. The clinical utility of polygenic risk scores for ischemic stroke prediction among atrial fibrillation patients has not yet been established.
Correlation between thrombocytopenia and adverse outcomes in patients with atrial fibrillation: a systematic review and meta-analysis
Frontiers in Cardiovascular Medicine
DECEMBER 3, 2024
BackgroundThrombocytopenia is often associated with adverse outcomes in patients with atrial fibrillation. ResultsA total of 12 studies included 73,824 patients with atrial fibrillation (average age: 72.67, males: 42,275, 57.3%), among them, there were 7,673 patients combined with thrombocytopenia.
Do patients with device-detected atrial fibrillation and prior stroke benefit from anticoagulation?
Medical Xpress - Cardiology
MAY 20, 2024
In patients with device-detected atrial fibrillation and a prior stroke, oral anticoagulation increases bleeding without a clear reduction in stroke. This finding was presented by Prof. May 16–19.
Does atrial fibrillation ablation prevent cardiovascular death, stroke, and heart failure events?
HeartRhythm
NOVEMBER 5, 2024
Recent trial results led to a renewed consideration of rhythm control therapy to improve outcomes in patients with atrial fibrillation (AF)1,2. The resulting shift towards rhythm control therapy for most patients with atrial fibrillation is reflected by new recommendations in the recent ESC3 and ACC/AHA/HRS4 AF guidelines.
Influence of ABC stroke score on late recurrence of paroxysmal atrial fibrillation following radiofrequency catheter ablation
Journal of Cardiothoracic Surgery
JUNE 20, 2024
In this study we investigated the impact of ABC stroke score on the recurrence of paroxysmal atrial fibrillation (PAF) following radiofrequency catheter ablation (RFCA).
News from EHRA 2024: International Experts Agree on Standards for Catheter Ablation of Atrial Fibrillation
DAIC
APRIL 9, 2024
An international consensus statement on how to treat atrial fibrillation with catheter or surgical ablation has been published in EP Europace, a journal of the European Society of Cardiology (ESC), and was recently presented at EHRA 2024, a scientific congress held April 7-9 in Berlin, Germany.
Early Versus Late Initiation of Direct Oral Anticoagulants in Postischemic Stroke Patients With Atrial Fibrillation
American College of Cardiology
JUNE 17, 2024
The goal of the ELAN trial was to evaluate early anticoagulation compared with delayed anticoagulation among patients with acute ischemic stroke and atrial fibrillation (AF).
ECG-based Stroke Prediction in Patients with Atrial Fibrillation – Time to Exploit the ECG!
HeartRhythm
SEPTEMBER 24, 2024
Atrial fibrillation (AF) is associated with increased risk for ischemic stroke, heart failure and death (1). In clinical practice, the CHA2DS2-VA score is routinely applied to identify AF patients with increased stroke risk, who would benefit from oral anticoagulant therapy.
ID: 4114415 Protocolized Atrial Fibrillation Monitoring in Stroke: Optimizing Practice Based on Data
HeartRhythm
AUGUST 31, 2024
Post-stroke cardiac monitoring to detect occult atrial fibrillation (AF) is highly variable across healthcare institutions. Gaps in care pathways and nonadherence to guidelines, as observed in DiVERT, underscore the unmet need for post-stroke cardiac monitoring protocols.
Anticoagulants for atrial fibrillation: from warfarin and DOACs to the promise of factor XI inhibitors
Frontiers in Cardiovascular Medicine
FEBRUARY 4, 2024
Anticoagulation is the mainstay of stroke prevention in appropriate patients with atrial fibrillation. An investigational class of agents which inhibit Factor XI have shown promise in pre-clinical and early clinical trials to significantly minimize bleeding while maintaining efficacy against stroke and systemic embolism.
The Effect of Implantable Loop Recorder based Continuous Rhythm Monitoring on Incident Atrial Fibrillation and Stroke: An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials
HeartRhythm
JUNE 4, 2024
In patients with a history of stroke or those at high risk of developing stroke, a continuous rhythm monitoring strategy using implantable loop recorders (ILR) is often performed to screen for atrial fibrillation (AF).
Artificial intelligence-enabled atrial fibrillation detection using smartwatches: current status and future perspectives
Frontiers in Cardiovascular Medicine
JULY 14, 2024
Atrial fibrillation (AF) significantly increases the risk of stroke and heart failure, but is frequently asymptomatic and intermittent; therefore, its timely diagnosis poses challenges. Early detection in selected patients may aid in stroke prevention and mitigate structural heart complications through prompt intervention.
Atrial Fibrillation and Stable Coronary Artery Disease
The New England Journal of Medicine
AUGUST 31, 2024
Patients with atrial fibrillation are at high risk for stroke, and international guidelines recommend oral anticoagulant therapy. In patients with stable vascular disease without atrial fibrillation, antiplatelet therapy is recommended. When patients with both conditions present with.
Rethinking Stroke Prevention for Patients with Atrial Fibrillation
HeartRhythm
MARCH 12, 2024
We are diagnosing atrial fibrillation (AF) more often that at any time in history. However, one of medicine’s great triumphs of the last 30 years has been the ability to prevent most AF-related strokes. However, one of medicine’s great triumphs of the last 30 years has been the ability to prevent most AF-related strokes.
Atrial fibrillation and stroke risk
Science Daily - Stroke
AUGUST 28, 2023
Researchers have developed a new way of identifying patients at risk of an irregular heartbeat, known as 'atrial fibrillation'. While not life threatening, the condition increases people's risk of having a transient ischaemic attack (TIA) or stroke by up to five times.
Management Strategies to Prevent Stroke in Patients with Atrial Fibrillation and Malignant Left Atrial Appendage
HeartRhythm
NOVEMBER 6, 2024
Patients with atrial fibrillation (AF) and malignant left atrial appendage (LAA) may benefit from LAA closure (LAAC); however, evidence is limited.
Those with stroke risk factors may be more likely to have severe strokes
Medical Xpress - Cardiology
NOVEMBER 13, 2024
People with conditions or habits such as high blood pressure, an irregular heartbeat called atrial fibrillation, or smoking, not only have a higher risk of stroke, they may also have more severe strokes than people without these risk factors, according to a study published in the journal Neurology.
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59 Mass screening for atrial fibrillation does not prevent stroke in older adults, research finds
Medical Xpress - Cardiology
SEPTEMBER 3, 2024
Mass screening for atrial fibrillation using ECG together with heart failure biomarker does not prevent ischemic stroke or systemic embolism (blood clot) in older adults aged 75–76 years over 5 years follow-up, according to late breaking research presented in a Hot Line Session at this year's ESC Congress 2024 in London, UK (30 Aug–2 Sept).
Asundexian Versus Apixaban in Patients With Atrial Fibrillation
American College of Cardiology
SEPTEMBER 1, 2024
The goal of the OCEANIC-AF trial was to determine whether asundexian, a direct and selective factor XIa inhibitor, is 1) noninferior in preventing stroke or systemic thromboembolism, and 2) superior with respect to major bleeding risk compared with apixaban in patients with atrial fibrillation (AF) requiring oral anticoagulant therapy.
Atrial Fibrillation Detection and Load: Knowledge Gaps Related to Stroke Prevention
Stroke Journal
NOVEMBER 21, 2023
Stroke, Ahead of Print. Atrial fibrillation is a major cause of ischemic stroke. Furthermore, the clinical significance of very short duration paroxysmal atrial fibrillation remains controversial.
Novel electrocardiographic classification for stroke prediction in atrial fibrillation patients undergoing cardioversion
HeartRhythm
APRIL 24, 2024
Abnormal conduction, structure and function of the atrial myocardium predispose to atrial fibrillation (AF) and stroke. Usefulness of electrocardiographic (ECG) indices in predicting stroke or systemic embolism (SSE) in patients undergoing cardioversion for AF remains unknown, especially in those at low estimated risk.
PO-04-093 IMPACT OF BRADYCARDIC SYNDROMES ON THE TEMPORAL TREND OF ISCHEMIC STROKE IN ATRIAL FIBRILLATION
HeartRhythm
APRIL 30, 2024
Bradycardic syndromes often complicate atrial fibrillation. Associations have been made between certain bradycardia and risk of strokes. The effect of bradycardia on stroke risk in atrial fibrillation is uncertain.
Apixaban for Stroke Prevention in Subclinical Atrial Fibrillation
The New England Journal of Medicine
NOVEMBER 11, 2023
In a randomized trial involving patients with subclinical (typically asymptomatic) atrial fibrillation, apixaban led to a lower risk of stroke or systemic embolism than aspirin but a higher risk of major bleeding.
Eagle’s Eye View: Cardiac Sarcoidosis, Ischemic Stroke in Women with Atrial Fibrillation, TAVR and Native Aortic Regurgitation
American College of Cardiology
APRIL 24, 2024
He then examines the temporal trends and clinical implications of ischemic stroke in women with atrial fibrillation. Eagle looks at a scientific statement from the American Heart Association on the diagnosis and management of cardiac sarcoidosis.
Predictors of atrial fibrillation detection in embolic stroke of undetermined source patients with implantable loop recorder
Frontiers in Cardiovascular Medicine
MARCH 3, 2024
Background Covert atrial fibrillation (AF) is a predominant aetiology of embolic stroke of undetermined source (ESUS). Evidence suggested that AF is more frequently detected by implantable loop recorder (ILR) than by conventional monitoring.
Popular supplement linked to increased heart, stroke risk
Becker's Hospital Review - Cardiology
MAY 23, 2024
Regular use of fish oil supplements can increase the risk of stroke and atrial fibrillation in the general population, but shows benefits for those with existing heart disease, a recent study found.
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Stroke Prevention in Atrial Fibrillation: Our Current Failures and Required Research
Stroke Journal
DECEMBER 21, 2023
Stroke, Volume 55, Issue 1 , Page 214-225, January 1, 2024. Nonvalvular atrial fibrillation is a common rhythm disorder of middle-aged to older adults that can cause ischemic strokes and systemic embolism.
Convergent Procedure to Treat Atrial Fibrillation
CTVS
AUGUST 22, 2023
It is estimated that more than 12 million people in the United States will have Atrial Fibrillation, or AFib in 2030. If left untreated, this erratic heartbeat can disrupt blood flow and lead to serious life-threatening issues like stroke or heart failure.
Biosense Webster Submits Application to U.S. FDA Seeking Approval of the VARIPULSE Platform for the Treatment of Paroxysmal Atrial Fibrillation
DAIC
MARCH 28, 2024
Primary adverse events were defined as myocardial infarction, thromboembolism, transient ischemic attack, diaphragmatic paralysis, pneumothorax, heart block, pulmonary edema, vagal nerve injury, pericarditis, major vascular access complication or bleeding, death, stroke, or any other cerebrovascular accident. Int J Stroke.
Optimal Timing of Anticoagulation After Acute Ischemic Stroke
American College of Cardiology
NOVEMBER 5, 2024
The goal of the OPTIMAS trial was to evaluate early compared with late initiation of direct oral anticoagulants (DOACs) among patients with acute ischemic stroke associated with atrial fibrillation.
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66 PO-04-052 A POLYGENIC RISK SCORE PREDICTS FUTURE ATRIAL FIBRILLATION-RELATED STROKE/SYSTEMIC EMBOLISM
HeartRhythm
APRIL 30, 2024
Polygenic risk score (PRS) might be useful in predicting atrial fibrillation (AF)-related stroke/systemic embolsim (SSE) before diagnosis of clinical AF.
Medtronic Creates History with FDA Approval of its Novel PulseSelect Pulsed Field Ablation System to Treat Atrial Fibrillation
DAIC
DECEMBER 14, 2023
About Atrial Fibrillation and Pulsed Field Ablation AF is one of the most common and undertreated heart rhythm disorders, affecting more than 60 million people worldwide3. Mortality trends in patients diagnosed with first atrial fibrillation: a 21-year community-based study. Stroke 1991;22:983-8. Eur Heart J 2020.
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