Physiologically Speaking

JULY 26, 2024

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. This irregular sleep pattern misaligns circadian rhythms and disrupts physiology. Deep sleep: Each percent increase in deep sleep was associated with a lower risk of atrial fibrillation, depression, and anxiety.

Chronic Disease 64

Chronic Disease Physiology Atrial Flutter Atrial Fibrillation 64

HeartRhythm

MARCH 6, 2024

Extensive ablation, including posterior wall isolation (PWI) is advocated for radiofrequency ablation (RFA) of persistent atrial fibrillation (peAF) to decrease the high recurrence-rates reported when only pulmonary vein isolation (PVI) is performed.1

Atrial Fibrillation 45

Atrial Fibrillation Ablation Physiology Pulmonary 45

HeartRhythm

MAY 17, 2024

The autonomic nervous system (ANS) is critical to atrial fibrillation (AF) pathophysiology, but it is often difficult to differentiate vagal and adrenergic AF due to complex physiological interactions.1 2 We previously reported that ERPs were associated with increased susceptibility to AF.3

Atrial Fibrillation 40

Atrial Fibrillation Electrocardiogram Physiology Ablation 40

HeartRhythm

JANUARY 25, 2024

Early recurrence of atrial arrhythmia (ERA) is commonly seen following catheter ablation of atrial fibrillation (AF), with reported incidences of up to 61% in the first three months.1 1 ERA is often attributed to transient inflammation induced by tissue damage during ablation and short-term imbalances in autonomic innervation.

Atrial Fibrillation 45

Atrial Fibrillation Ablation Arrhythmia Physiology 45

Circulation: Arrhythmia and Electrophysiology

FEBRUARY 10, 2025

BACKGROUND:It is difficult to identify patients with atrial fibrillation (AF) most likely to respond to ablation. and 0.64, respectively) with similar phenotypes.CONCLUSIONS:Long-term and acute responses to AF ablation reflect distinct clinical and electrical physiology, respectively.

Atrial Fibrillation 40

Atrial Fibrillation Ablation Physiology Arrhythmia 40

MIBHS

JANUARY 31, 2025

The Role of Wearable Technology in Heart Health Wearable tech is designed to monitor physiological data and provide actionable insights to users. Detection of Irregular Heart Rhythms Devices such as the Apple Watch or Fitbit Sense can detect irregular heart rhythms, including atrial fibrillation (AFib).

Heart Rhythm 52

Heart Rhythm Technology AFIB Exercise 52

HeartRhythm

AUGUST 6, 2024

In the article, “Pulsed field ablation prevents left atrial restrictive physiology after posterior wall isolation in patients with persistent atrial fibrillation” by Ariel Banai and colleagues, published in the August 2024 issue of Heart Rhythm (21;8:1245-1247), the author Disclaimer information was incomplete.

Atrial Fibrillation 40

Atrial Fibrillation Article Heart Rhythm Physiology 40

Cardiomatics

APRIL 5, 2024

Then, the current flows to an area known as the bundle of His, which divides into two branches (LBB and RBB) and is the only physiological pathway connecting the atria with the ventricles. AFIB/AFL – atrial fibrillation or atrial flutter episodes. The left bundle and right bundle terminate in the Purkinje fibers.

Arrhythmia 92

Arrhythmia Tachycardia Bradycardia Electrocardiogram 92

The British Journal of Cardiology

DECEMBER 3, 2024

Atrioventricular nodal (AVN) ablation with permanent pacemaker implantation – ‘pace and ablate’ – may be considered for patients with symptomatic atrial fibrillation (AF) for whom rhythm control has been unsuccessful. This creates concerns about inducing pacemaker dependence and potential pacemaker-induced cardiomyopathy (PICM).

Ablation 40

Ablation Pacemaker Atrial Fibrillation Physiology 40

Stroke Journal

MARCH 8, 2024

The bulk of the current knowledge on atrial fibrillation (AF)-associated stroke risk and benefit of oral anticoagulation derives from studies on patients with clinically diagnosed AF. Stroke, Ahead of Print.

Heart Rhythm 40

Heart Rhythm Stroke Strokes Atrial Fibrillation 40

Stroke: Vascular and Interventional Neurology

JUNE 20, 2024

The foods we eat, coupled with our physiology and exposures (eg, antibiotics, supplements), directly contribute to atherosclerotic disease in complex ways that are mediated by gastrointestinal flora and metabolic byproducts.

Cerebrovascular Disease 40

Cerebrovascular Disease Atherosclerosis Atrial Fibrillation Physiology 40

Dr. S. Venkatesan MD

MARCH 28, 2025

We know Left atrial size typically reflects the chronicity of elevated left atrial pressure or volume overload, which can result from conditions such as mitral valve disease, left ventricular dysfunction, or atrial fibrillation. 160240 ms), and LA size does not significantly influence DT.

Bicuspid/Mitral 52

Bicuspid/Mitral Atrial Fibrillation Hypertension Physiology 52

Circulation: Arrhythmia and Electrophysiology

DECEMBER 21, 2023

BACKGROUND:MicroRNA-1 (miR1), encoded by the genesmiR1-1andmiR1-2, is the most abundant microRNA in the heart and plays a critical role in heart development and physiology.

Electrophysiology 40

Electrophysiology Myocardial Infarction Atrial Fibrillation Arrhythmia 40

The British Journal of Cardiology

MAY 14, 2024

This review describes the physiological rationale behind FXI/FXIa inhibition and the pharmacological properties of existing FXI/FXIa inhibitors.

Thrombosis 40

Thrombosis Pharmacology Physiology Atrial Fibrillation 40

Dr. Smith's ECG Blog

JANUARY 9, 2024

She also has a hx of paroxysmal atrial fibrillation and is on oral anticoagulant treatment. The patient’s own underlying atrial rhythm is revealed at a heart rate in the mid 50s. AV synchrony and physiologic ventricular depolarization the hemodynamics improved. The last echocardiography 12 months ago showed HFmrEF.

Tachycardia 118

Tachycardia Electrophysiology Atrial Flutter Ischemia 118

Dr. Smith's ECG Blog

APRIL 6, 2023

Here is the previous ECG from 2 months prior for pre-op for cataract surgery This appears to be atrial fibrillation with RBBB and LAFB. This was interpreted as "Atrial Fibrillation". This was interpreted as "Atrial Fibrillation". They compared to a previous ECG and thought they were identical.

Arrhythmia 52

Arrhythmia Atrial Fibrillation AFIB Outpatient 52

Open Heart

MARCH 31, 2025

Background Atrial fibrillation (AF) is a common but often undiagnosed condition, increasing the risk of stroke and heart failure. Methods We analysed 35 634 12-lead ECG recordings from three public databases (China Physiological Signal Challenge-Extra, PTB-XL and Georgia), each with physician-validated AF labels.

Atrial Fibrillation 52

Atrial Fibrillation Physiology Heart Failure Stroke 52

Dr. Smith's ECG Blog

NOVEMBER 19, 2016

Smith comment: In a large randomized trial of dopamine vs. norepinephrine (11) for shock which was published after the above-mentioned recommendations, dopamine had more adverse events (especially severe dysrhythmias, and especially atrial fibrillation). Any alteration in physiology can change "compensated" AS to "decompensated" AS.

Ischemia 40

Ischemia Cardiogenic Shock Aortic Stenosis 40

Dr. Paddy Barrett

SEPTEMBER 26, 2023

Share For people with OSA during sleep, there are recurrent episodes where the airway collapses and obstructs the passage of air to the lungs, resulting in: Lack of oxygen Significant variations in blood pressure, heart rate and other physiological metrics. It significantly increases the risk of heart attack, stroke and atrial fibrillation.

Blood Pressure 52

Blood Pressure Cardiovascular Disease Atrial Fibrillation Coronary Artery Disease 52

Circulation

NOVEMBER 10, 2023

Physiologic resynchronization by LBBAP may be associated with lower risk of arrhythmias compared with BVP. The incidence of AF lasting >24 hours was also significantly lower with LBBAP compared with BVP (0.7% Conclusions:LBBAP was associated with lower incidence of sustained VT/VF and new-onset AF compared with BVP.

Atrial Fibrillation 40

Atrial Fibrillation Pacemaker Physiology Heart Failure 40

Dr. Smith's ECG Blog

NOVEMBER 26, 2018

Chart review confirmed that he had been started on flecainide for atrial fibrillation. This new information makes the diagnosis of atrial flutter far more likely: first, atrial fibrillation and flutter are closely associated and, second, this makes a flutter rate of 200 bpm (with 1:1 conduction) quite likely.

Ischemia 52

Ischemia Atrial Flutter Arrhythmia Tachycardia 52

Physiologically Speaking

SEPTEMBER 13, 2024

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. This study is " atypical " because it’s a case study — an n=1 characterization of an extreme outlier of physiology, performance, and healthy aging. How much exercise is too much exercise?

Physiology 105

Physiology Exercise Atrial Fibrillation Risk Factors 105

Cardiometabolic Health Congress

DECEMBER 7, 2023

The American College of Cardiology (ACC) and the American Heart Association (AHA) recently published new guidelines for the diagnosis and management of patients with atrial fibrillation (AF). link] ACC/AHA Release Updated Atrial Fibrillation Guidelines for 2023. Sources: Joglar, J, Chung, M. J Am Coll Cardiol.

Atrial Fibrillation 111

Atrial Fibrillation Risk Factors Ablation Stroke 111

Dr. Smith's ECG Blog

OCTOBER 10, 2022

The rhythm is atrial fibrillation. The ECG accurately reflects the physiologic state of the underlying myocardium, but there is always more than one possible etiology of that physiologic state. Initial ROSC was obtained, during which this ECG was obtained: What do you think? The QRS complex is within normal limits.

Cardiac Arrest 52

Cardiac Arrest Chest Pain Embolism Pulmonary 52

Dr. Smith's ECG Blog

NOVEMBER 24, 2017

Rate correction should not be used when RR interval has large variability, as in atrial fibrillation. Atrial Fibrillation: These authors compared Bazett, Fridericia, and Framingham QT measurements on 54 patients with atrial fibrillation. Dangerously prolonged QT is 480, especially greater than 500 ms.

Bradycardia 52

Bradycardia Article Atrial Fibrillation Chest Pain 52

Dr. S. Venkatesan MD

JANUARY 28, 2025

If we look at the above map,RA prevails over LA convincigly in termes of focal atrial tachycardia. Focus-less Atrial fibrillation Right from the days of James Mckenzie , when AF was refered to as delirium cordis or ataxia of pulse, AF was always considered as a chaotic, focus-less arrhythmia. It is still true in many cases.

Atrial Fibrillation 52

Atrial Fibrillation Pulmonary Tachycardia Electrophysiology 52

Dr. Smith's ECG Blog

APRIL 8, 2015

Rhythm abnormalities (atrial fibrillation or flutter, supraventricular tachycardia, multifocal atrial tachycardia, frequent or repetitive premature supraventricular or ventricular complexes, sustained or non-sustained ventricular tachycardia, paced rhythms), 2. The tracings were considered abnormal in the following cases: 1.

Arrhythmia 52

Arrhythmia Outcomes Chest Pain Risk Factors 52

Dr. Smith's ECG Blog

DECEMBER 20, 2024

Conduction system pacing" is a newer technique that is being studied as a way of delivering more physiologic pacing, typically by inserting a lead into the area of the left bundle branch, or the bundle of His. Cardioversion will momentarily reset the AT, but it will likely recur immediately.

Chest Pain 101

Chest Pain Tachycardia Pacemaker Defibrillator 101

DAIC

MARCH 17, 2025

edition of CardioLab offers improved signal quality for visualization of physiological signals using the Prucka 3 digital amplifier. The feature is designed to support clinicians with real-time assessments using artificial intelligence (AI) to automatically assess areas believed to initiate or maintain atrial fibrillation drivers.

Document 59

Document Coronary Artery Disease Innovation Cardiovascular Disease 59

Dr. Smith's ECG Blog

MARCH 8, 2025

2:34 PM, following right heart catheterization She then went into atrial fibrillation with complete heart block and junctional escape rhythm prompting placement of transvenous pacemaker. Clearly the physiologic chain reaction of autonomic dysfunction seen in todays case does not commonly lead to death of the person learning this news.

Cardiomyopathy 74

Cardiomyopathy Myocardial Infarction Defibrillator Bradycardia 74