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Journal of Clinical Investigation - Cardiology
SEPTEMBER 17, 2024
Obesity is linked to an increased risk of atrial fibrillation (AF) via increased oxidative stress. Here, we studied NOX2-mediated ROS production in obesity-mediated AF using Nox2-knockout mice and mature human induced pluripotent stem cell–derived atrial cardiomyocytes (hiPSC-aCMs).
JAMA Cardiology
MAY 21, 2024
This randomized clinical trial investigates which strategy is more effective in patients with atrial fibrillation and obesity: dual or single direct-current cardioversion.
Frontiers in Cardiovascular Medicine
FEBRUARY 7, 2024
Background Efforts to maintain sinus rhythm in patients with persistent atrial fibrillation (PsAF) remain challenging, with suboptimal long-term outcomes. Twelve (50%) patients were obese. Methods All patients undergoing convergent PsAF ablation at our centre were retrospectively analysed. All were longstanding persistent.
American College of Cardiology
JANUARY 8, 2024
Obesity is a multifaceted disease that is directly and indirectly implicated in atherosclerotic cardiovascular disease (CVD), heart failure (HF), atrial fibrillation (AF), and multiple CVD risk factors, including dyslipidemia, hypertension, type 2 diabetes mellitus (DM), and sleep disorders.
71 
Medical Xpress - Cardiology
JANUARY 21, 2025
Atrial fibrillation, or A-fib, is an irregular heart rhythm that increases a person's risk of stroke, heart failure and even premature death.
75 
American College of Cardiology
JUNE 4, 2024
The goal of the Dual vs. Single DCCV trial was to determine the efficacy and safety of dual direct-current cardioversion (DCCV) compared with single DCCV in patients with obesity and atrial fibrillation (AF) undergoing elective electrical cardioversion.
58 
Journal of the American Heart Association
JANUARY 10, 2025
BackgroundThe economic burden of nonvalvular atrial fibrillation (NVAF) is substantial. Many patients with NVAF are obese and manage other health conditions requiring multiple medications. Journal of the American Heart Association, Ahead of Print.
HeartRhythm
APRIL 30, 2024
Catheter Ablation for Atrial Fibrillation (AFib) in heart failure is now a class I indication for patients with heart failure. Evidence supports the relationship between obesity and the incidence and recurrence of Afib.
Cardiovascular Diabetology
DECEMBER 20, 2024
Atrial fibrillation (AF) is the most prevalent arrhythmia in clinical practice, and obesity serves as a significant risk factor for its development. The underlying mechanisms of obesity-related AF remain intri.
Frontiers in Cardiovascular Medicine
APRIL 18, 2024
BackgroundAtrial fibrillation (AF) is a common cardiac arrhythmia that is associated with obesity and obstructive sleep apnea syndrome (OSA). Through mediating MR analysis, it was found that OSA played a certain role in the causal relationship between obesity and AF, with about 6.4%
52 
Frontiers in Cardiovascular Medicine
DECEMBER 13, 2023
Cancer, atrial fibrillation (AF) and coronary artery disease share some common factors and interact with each other, such as obesity, aging, diabetes, and inflammation, but the potential specific mechanism is still unclear. Meanwhile, the risk of suffering from cardiovascular disease (CVD) has been increasing with ageing.
Journal of the American Heart Association
DECEMBER 29, 2023
ABSTRACTAtrial fibrillation (AF) is the most common cardiac arrhythmia. Obesity significantly increases AF risk, both directly and indirectly, through related conditions, like hypertension, diabetes, and heart failure. However, studies on how obesity affects pharmacologic or interventional AF treatments are limited.
45 
DAIC
SEPTEMBER 11, 2024
million Americans have atrial fibrillation. Atrial fibrillation, a rapid, irregular heart beat that can lead to stroke or sudden death, is three times more common than previously thought, affecting nearly 5 percent of the population, or 10.5 tim.hodson Wed, 09/11/2024 - 15:40 Sept. million U.S. million U.S.
Dr. S. Venkatesan MD
NOVEMBER 22, 2024
Atrial fibrillation: Think locally act globally It is clear, except in specific situations like HT, LVH, HFpEF, and other left (or right )sided structural heart diseases, the bulk of the AF is part of systemic destabilization of neuro-metabolic homeostasis. Epicardial Fat and Atrial Fibrillation: A Review. 2017.11.001.
HeartRhythm
APRIL 30, 2024
Following pulmonary vein isolation (PVI), about a third of patients have a very late recurrence (VLR) of atrial fibrillation (AF), defined as an AF recurrence after being free of AF for the first year following ablation. Additional data are needed to understand which patients remain at risk for VLR.
HeartRhythm
MARCH 12, 2024
1 Atrial fibrillation (AF) is the most common cardiac arrhythmia, affecting more than 6 million individuals in the United States.2 2 As noted elsewhere,3 DM and AF affect a population that shares concomitant conditions such as obesity, hypertension and even heart failure (HF). of the population.1
HeartRhythm
APRIL 30, 2024
Aging is a risk factor for atrial fibrillation (AF). In 19-month-old mice, increases in AF inducibility are associated with an increase in the levels of the fat mass and obesity-associated (Fto) protein, and a reduction of N6-Methyladenosine (m6A) modification in atrial tissue.
Open Heart
JULY 17, 2023
Objective Atrial fibrillation (AF) is a condition that occurs in the presence of comorbidities. years), obese and hypertensive cluster carrying an intermediate risk (5.9%) of incident AF. With the accumulation of comorbidities (multimorbidity), some combinations may more often occur together than others.
Frontiers in Cardiovascular Medicine
DECEMBER 18, 2024
Atrial fibrillation (AF), the most prevalent cardiac arrhythmia, is closely linked to metabolic dysfunctions, including obesity, diabetes, and dyslipidemia. These lead to pathological changes in myocardial metabolism and mitochondrial energy metabolism, thereby aggravating AF's incidence and severity.
HeartRhythm
SEPTEMBER 4, 2024
Heart failure with preserved ejection fraction (HFpEF) and atrial fibrillation (AF) are comorbid conditions that are increasingly prevalent and have a high socioeconomic burden. This article discusses their shared pathophysiology, focusing on the triad of hypertension, obesity, and aging.We
HeartRhythm
APRIL 30, 2024
We previously reported that first-pass pulmonary vein (PV) isolation (FPI) is related to the PV isolation (PVI) durability in ablation index (AI) guided catheter ablation for atrial fibrillation (AF) (J Cardiovasc Electrophysiol 2023). However, the impact of obesity on FPI has been scarcely reported.
40 
DAIC
JUNE 18, 2024
A projected rise in heart disease and stroke – along with several key risk factors, including high blood pressure and obesity – is likely to triple related costs to $1.8 A projected rise in heart disease and stroke – along with several key risk factors, including high blood pressure and obesity – is likely to triple related costs to $1.8
105 HeartRhythm
AUGUST 31, 2024
Atrial Fibrillation (AF) is a heart arrhythmia with influences from lifestyle risk factors like alcohol use and obesity. As such, patient lifestyles have a prominent role in managing AF.
All About Cardiovascular System and Disorders
FEBRUARY 27, 2024
They have a greater prevalence of obesity, dyslipidemia, metabolic syndrome and diabetes mellitus. Higher risk of myocardial infarction, heart failure and atrial fibrillation was noted in spinal cord injury survivors compared to controls. Survivors with severe disability had the highest risk. Am J Phys Med Rehabil. 2023.12.010.
NEJM Journal Watch - Cardiology
FEBRUARY 13, 2024
Results from a pooled analysis of pivotal trials suggest preserved efficacy across a wide range of body weights and body-mass indices.
DAIC
JULY 31, 2024
It incorporates age, body mass index (BMI), and atrial fibrillation to aid in the diagnosis of HFpEF. The newly developed HFpEF-ABA score model estimates the probability of HFpEF in individual patients based on three simple clinical variables: age, BMI, and atrial fibrillation.
111 Circulation
JUNE 4, 2024
to 26.8%) and obesity (43.1% to 6.4%), atrial fibrillation (1.7% We projected through 2050, overall and by age and race and ethnicity, accounting for changes in disease prevalence and demographics.RESULTS:We estimate that among adults, prevalence of hypertension will increase from 51.2% in 2020 to 61.0% Diabetes (16.3%
81 
DAIC
DECEMBER 8, 2023
Getty Images milla1cf Fri, 12/08/2023 - 08:17 December 8, 2023 — The American College of Cardiology (ACC) and the American Heart Association (AHA), along with several other leading medical associations, have issued a new guideline for preventing and optimally managing atrial fibrillation (AFib).
The British Journal of Cardiology
AUGUST 6, 2024
Atrial fibrillation (AF) is responsible for significant patient morbidity, and obesity is a major contributor to AF incidence and symptom burden. This randomised study set out to examine if smartphone-based app technology could increase weight loss in a patient population with obesity and AF.
Journal of Cardiovascular Electrophysiology
DECEMBER 7, 2023
Abstract Background Obesity is associated with an increased risk of developing recurrent atrial fibrillation (AF) after catheter ablation (CA). However, the current data on weight loss interventions show inconsistent results in preventing the recurrence of AF after CA.
DAIC
FEBRUARY 7, 2024
For ICM patients who are at the highest risk of AF detection (those with left atrial enlargement, heart failure , obesity, or prolonged QRS), the cost per QALY is reduced even further to $22,016. “In Additionally, patients with ICMs were estimated to experience a gain of 0.17 of $150,000 per QALY.
Circulation
NOVEMBER 11, 2024
vs. 43.6%, p=0.007), and were less often obese (34.0% Circulation, Volume 150, Issue Suppl_1 , Page A4141940-A4141940, November 12, 2024. Compared to the no prior SSE group, those with prior SSE were less symptomatic (61.3% vs. 72.8%, p<0.001), had higher rates of diabetes (49.1% vs. 42.4%, p=0.03) and dyslipidemia (51.9%
DAIC
SEPTEMBER 11, 2024
million Americans have atrial fibrillation. Atrial fibrillation, a rapid, irregular heart beat that can lead to stroke or sudden death, is three times more common than previously thought, affecting nearly 5 percent of the population, or 10.5 tim.hodson Wed, 09/11/2024 - 15:40 Sept. million U.S. million U.S.
Frontiers in Cardiovascular Medicine
JANUARY 7, 2024
Objectives In dyspneic patients with atrial fibrillation (AF) or obesity, the diagnostic performance of NT-proBNP for acute heart failure is reduced. The diagnostic performance of ERFE is impaired in patients with AF but not patients with obesity.
HeartRhythm
APRIL 30, 2024
Obesity, diabetes, and the metabolic syndrome are risk factors for atrial fibrillation (AF). AF is also associated with cardiomyocyte metabolic stress. We hypothesized that antidiabetic medications (ADMs) may affect AF incidence.
ADN Center of Excellence
SEPTEMBER 2, 2024
September is National Atrial Fibrillation (AFib) Awareness Month, a time dedicated to raising awareness about one of the most common yet often misunderstood heart conditions. Understanding Atrial Fibrillation Atrial Fibrillation is characterized by an irregular and often rapid heart rhythm that can lead to poor blood flow.
59 Stroke Journal
FEBRUARY 1, 2024
Introduction:Identification of atrial fibrillation (AF) in patients with stroke is critical for secondary stroke prevention with guideline-recommended oral anticoagulation (OAC). In the patients at highest risk of AF detection (left atrial enlargement, heart failure, obesity, or prolonged QRS), the cost/QALY was $22,016.Conclusions:ICMs
ADN Center of Excellence
SEPTEMBER 2, 2024
September is National Atrial Fibrillation (AFib) Awareness Month, a time dedicated to raising awareness about one of the most common yet often misunderstood heart conditions. Understanding Atrial Fibrillation Atrial Fibrillation is characterized by an irregular and often rapid heart rhythm that can lead to poor blood flow.
52 
Journal of Cardiovascular Electrophysiology
DECEMBER 17, 2024
Obesity is associated with reduced catheter ablation-induced scar formation on late-gadolinium enhancement MRI. Abstract Introduction Obesity is implicated in adverse atrial remodeling and worse outcomes in patients with atrial fibrillation. Comorbidities were more prevalent in obese patients.
40 
Cardiometabolic Health Congress
FEBRUARY 23, 2024
Black History Month is a poignant backdrop to the alarming rise in obesity and type 2 diabetes, particularly among those of marginalized populations. This troubling trend has cemented the 100-year reign of cardiovascular diseases (CVD) as the #1 killer in America.
105 
CardiacWire
OCTOBER 27, 2024
Heart Disease in 2050 – The AHA warned of massive heart disease increases by 2050, spanning CVD (+60%), diabetes (+100%), obesity (+70%), hypertension (+44%), heart failure (+66%), and stroke (+100%). AFib Wakeup Call – A JACC study suggested that atrial fibrillation is far more prevalent than many thought.
59 
Dr. Paddy Barrett
JANUARY 23, 2024
Atrial fibrillation, a common consequence of high blood pressure in Western populations, is almost unheard of in the Tsimane Tribe. For other significant risk factors, the trend is also the same, with almost nonexistent rates of obesity, abnormal glycemic control and very low rates of smoking 14. Am J Phys Anthropol.
101 
DAIC
FEBRUARY 29, 2024
24 will focus on the following three current guideline updates: American College of Cardiology (ACC)/American Heart Association (AHA) Guidelines 2023 Atrial Fibrillation Guideline - Pharmacology II: Strokes vs. Bleeds, What Do the Guidelines Tell Us About Practical Management in A-fib? The Guidelines Sessions at ACC.24
103 
Circulation
JANUARY 22, 2025
Optimal NT-proBNP cut points for HFpEF rule out (optimizing sensitivity) and rule in (optimizing specificity) were derived and tested, stratified by obesity and atrial fibrillation. In our study, NT-proBNP provided little value in those with AF and dyspnea because the presence of AF is by itself a robust biomarker of HFpEF.
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