article thumbnail

Atrial fibrillation: A review

Science Daily - Heart Disease

atrial fibrillation (AF), a heart condition that causes an irregular heartbeat in the upper chambers of the heart, affects up to one in three people in their lifetime. Significant complications associated with this condition include ischemic stroke, heart failure, myocardial infarction, chronic kidney disease, dementia and mortality.

article thumbnail

Bioinformatics analysis of the expression of potential common genes and immune-related genes between atrial fibrillation and chronic kidney disease

Frontiers in Cardiovascular Medicine

Research objectiveThis study is based on bioinformatics analysis to explore the co-expressed differentially expressed genes (DEGs) between atrial fibrillation (AF) and chronic kidney disease (CKD), identify the biomarkers for the occurrence and development of the two diseases, investigate the potential connections between AF and CKD, and explore the (..)

article thumbnail

Effectiveness and Safety of Apixaban and Warfarin in Patients with New Onset Atrial Fibrillation after Advanced Chronic Kidney disease or End-Stage Kidney Disease

HeartRhythm

Limited evidence supports apixaban's use for atrial fibrillation (Af) in severe chronic kidney disease (CKD) or end-stage kidney disease (ESKD) patients, where warfarin is often contraindicated.

article thumbnail

Efficacy and Safety of DOACs versus Vitamin K Antagonists in Patients with Atrial Fibrillation and Chronic Kidney Disease undergoing Hemodialysis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials with Trial Sequential Analysis

HeartRhythm

Atrial fibrillation (AF) is a relatively prevalent arrhythmia in patients with kidney failure requiring dialysis, who face a high risk of stroke and bleeding, and anticoagulation is a challenging decision.

article thumbnail

Predicting future atrial fibrillation: risk factors, proteomics and beyond

Heart BMJ

The term ‘epidemic’ is increasingly used to describe the rising global prevalence of atrial fibrillation (AF). The association between AF and various conditions—including hypertension, heart failure, sleep apnoea and chronic kidney disease—is well-described, highlighting that AF is often a multisystem disorder.

article thumbnail

Abstract WP171: Antithrombotic Therapy for Secondary Stroke Prevention in Patients with Severe Chronic Kidney Disease and Atrial Fibrillation

Stroke Journal

Background:The prevalence of renal disease is increasing in the U.S. Renal dysfunction increases risk of atrial fibrillation, ischemic stroke and systemic bleeding. For the analysis, subjects were categorized as advanced chronic kidney disease (CKD, CrCl 15-30) and end stage renal disease (ESRD, CrCl<15).Results:Of

article thumbnail

Association of Chronic Kidney Disease and Kidney Failure with Replacement Therapy with Procedural and Long-Term Outcomes after First Generation Watchman Device: Insights from the NCDR LAAO Registry

HeartRhythm

Chronic kidney disease (CKD) and kidney failure with replacement therapy (KFRT) are prevalent in patients with atrial fibrillation (AF).