Does Screening for Atrial Fibrillation Reduce Stroke Risk?
NEJM Journal Watch - Cardiology
SEPTEMBER 30, 2024
A 14-day monitor detected more atrial fibrillation but did not affect hospitalization rates for stroke or hemorrhage.
Study compares rivaroxaban, warfarin with apixaban for cirrhosis, atrial fibrillation
Medical Xpress - Cardiology
JULY 9, 2024
For patients with cirrhosis and nonvalvular atrial fibrillation (AF), initiators of rivaroxaban or warfarin versus apixaban have significantly higher rates of major hemorrhage, according to a study published online July 9 in the Annals of Internal Medicine.
Comparing Efficacy and Safety Between Patients With Atrial Fibrillation Taking Direct Oral Anticoagulants or Warfarin After Direct Oral Anticoagulant Failure
Journal of the American Heart Association
DECEMBER 1, 2023
BackgroundAn increased risk of recurrent stroke is noted in patients with atrial fibrillation despite direct oral anticoagulant (DOAC) use. We identified 3759 patients with DOAC failure.
Long‐Term Statin Use Is Associated With Reduced Rates of Adverse Events in Patients With Newly Diagnosed Atrial Fibrillation
Journal of the American Heart Association
DECEMBER 14, 2024
BackgroundThe effectiveness of statin use in preventing adverse cardiovascular events in individuals with atrial fibrillation (AF) has remained uncertain. Journal of the American Heart Association, Volume 13, Issue 24 , December 17, 2024.
Young man with Gunshot wound to right chest with hemorrhagic shock, but bullet path not near heart
Dr. Smith's ECG Blog
MARCH 7, 2024
A young man presented with a gunshot wound to the right chest, with hemo-pneumothorax and hemorrhagic shock. There is no atrial activity to suggest atrial fibrillation. He got a chest tube and intubation and massive transfusion and stabilized. But he did get an EKG: What is this? There is a wide complex. It is irregular.
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PO-02-031 HEMORRHAGIC SHOCK SECONDARY TO HEAT TRANSFER INJURY: A RARE COMPLICATION FOLLOWING RADIOFREQUENCY ABLATION FOR ATRIAL FIBRILLATION
HeartRhythm
APRIL 30, 2024
Radiofrequency (RF) ablation is an effective, and generally safe atrial fibrillation (AF) treatment. We present a case of a rare complication that rapidly progressed to hemorrhagic shock following RF ablation. Major complications requiring blood transfusion or surgical intervention are rare.
Efficacy and Safety of Non–Vitamin-K Antagonist Oral Anticoagulants Versus Warfarin Across the Spectrum of Body Mass Index and Body Weight: An Individual Patient Data Meta-Analysis of Four Randomized Clinical Trials of 58?464 Patients With Atrial Fibrillation
Circulation
JANUARY 24, 2024
The primary efficacy and safety outcomes were stroke or systemic embolic events (stroke/SEE) and major bleeding, respectively; secondary outcomes were ischemic stroke/SEE, intracranial hemorrhage, death, and the net clinical outcome (stroke/SEE, major bleeding, or death). Each outcome was examined across BMI and BW. interquartile range, 25.2–32.2)
PO-06-187 PULMONARY HEMORRHAGE DURING CRYOABLATION FOR ATRIAL FIBRILLATION: AN UNUSUAL COMPLICATION
HeartRhythm
APRIL 30, 2024
Cryoablation for atrial fibrillation is a widely used technique for pulmonary vein isolation. Known complications associated with cryoablation include tamponade, phrenic nerve injury, stroke, pulmonary embolism, pulmonary vein stenosis, and atrioesophageal fistulas.
Abstract 49: Genomic Profiling and Risk of Intracerebral Hemorrhage in Patients with Atrial Fibrillation on Apixaban
Stroke Journal
JANUARY 30, 2025
Introduction:Intracranial hemorrhage (ICH) is the most severe adverse effect of anticoagulation in atrial fibrillation (AF) patients. Stroke, Volume 56, Issue Suppl_1 , Page A49-A49, February 1, 2025. Hypertension, diabetes, hyperlipidemia, and chronic kidney disease are well-known cardiovascular risk factors for ICH.
Stroke Prevention in Atrial Fibrillation: Our Current Failures and Required Research
Stroke Journal
DECEMBER 21, 2023
Nonvalvular atrial fibrillation is a common rhythm disorder of middle-aged to older adults that can cause ischemic strokes and systemic embolism. Lifelong use of oral anticoagulants reduces the risk of these ischemic events but increases the risk of major and clinically relevant hemorrhages.
Use of Direct?Acting Oral Anticoagulants in Patients With Atrial Fibrillation and Significant Tricuspid Regurgitation
Journal of the American Heart Association
JANUARY 31, 2024
BackgroundThere are limited data on the efficacy and safety of direct oral anticoagulants (DOACs) in patients with atrial fibrillation with significant tricuspid regurgitation (TR), which can lead to hepatic dysfunction and intestinal malabsorption. 1.36];P=0.79) and major bleeding (aHR, 0.78 [95% CI, 0.57–1.06];P=0.11). 1.06];P=0.11).
Abstract DP39: Short-term Outcomes of Atrial Fibrillation Patients Undergoing Carotid Stent Placement or Carotid Endarterectomy in the United States
Stroke Journal
JANUARY 30, 2025
Background:Patients with atrial fibrillation were excluded from clinical trials evaluating carotid artery stent(CAS) or carotid endarterectomy (CEA).We We divided patients based on presence or absence of atrial fibrillation. Stroke, Volume 56, Issue Suppl_1 , Page ADP39-ADP39, February 1, 2025. versus 18.8%
Atrial Fibrillation and Clinical Outcomes of Endovascular Thrombectomy for Acute Ischemic Stroke: A Meta?Analysis of Adjusted Effect Estimates
Journal of the American Heart Association
DECEMBER 18, 2023
BackgroundThe impact of atrial fibrillation (AF) on the clinical outcomes in patients with acute ischemic stroke (AIS) who received endovascular thrombectomy remains unclear. 1.11]), symptomatic intracranial hemorrhage (OR, 0.97 [95% CI, 0.71–1.32]; 2.17]), and any intracranial hemorrhage (OR, 1.08 [95% CI, 0.91–1.28];
Abstract 145: New Oral Anticoagulant Therapy Versus Warfarin In Patients With Atrial Fibrillation And Previous Stroke or Transient Ischemic Attack. An Updated Meta-analysis.
Stroke Journal
JANUARY 30, 2025
Background:Patients with atrial fibrillation (AF) and previous stroke or transient ischemic attack (TIA) are at high risk of recurrent stroke. Heterogeneity was examined using I2statistics.Results:We included 7 RCTs and 2 non-RCTs comparing NOAC to warfarin in patients with atrial fibrillation and previous stroke or TIA.
Efficacy and Safety of Direct Oral Anticoagulants for Stroke Prevention in Older Patients With Atrial Fibrillation: A Network Meta?Analysis of Randomized Controlled Trials
Journal of the American Heart Association
NOVEMBER 28, 2023
BackgroundAlthough older patients with atrial fibrillation are at heightened risk of thromboembolic and bleeding events, their optimal treatment choice remains uncertain.Methods and ResultsThis meta‐analysis was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses guidelines. prospero/.
Impact of Anemia on Clinical Outcomes in Atrial Fibrillation Patients on Oral Anticoagulants: A Prognostic Meta‐Analysis
Journal of Cardiovascular Electrophysiology
DECEMBER 23, 2024
ABSTRACT Background Anemia is frequently observed as a comorbidity in atrial fibrillation (AF), especially in elderly patients and in those on anticoagulation. with 95% CI [1.59, 2.13], p <0.01), a 32% increase in the risk of intracranial hemorrhage (HR: 1.32 This has been associated with poor clinical outcomes.
Abstract WP12: Early or Later Anticoagulation in Post-Stroke Patients With Atrial Fibrillation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Stroke Journal
FEBRUARY 1, 2024
Introduction:Uncertainty regarding the timing of anticoagulant initiation after an ischemic stroke in patients with atrial fibrillation arises from the lack of extensive data on this matter. Stroke, Volume 55, Issue Suppl_1 , Page AWP12-AWP12, February 1, 2024. Statistical analyses were performed using R software version 5.4.1.Results:We
Pulsed Field Ablation Using Focal Contact Force–Sensing Catheters for Treatment of Atrial Fibrillation: 1-Year Outcomes of the ECLIPSE AF Study
Circulation: Arrhythmia and Electrophysiology
DECEMBER 19, 2024
BACKGROUND:Pulsed field ablation (PFA) is a promising treatment for atrial fibrillation. Patients with paroxysmal or persistent atrial fibrillation underwent pulmonary vein (PV) isolation under deep sedation or general anesthesia and returned for remapping at 90 days to evaluate chronic durability. paroxysmal, and 58.5%
Abstract 66: Optimal Delay Time to Initiate Anticoagulation After Ischemic Stroke in Atrial Fibrillation: Primary Results of the START Trial
Stroke Journal
FEBRUARY 1, 2024
Introduction:Clinical practice guidelines recommend initiation of anticoagulation within 2 weeks after stroke due to atrial fibrillation (AF). The primary outcome was an ischemic (stroke or systemic embolus) or hemorrhagic (ICH or major systemic hemorrhage) event observed within 30 days from the index stroke time of onset.
Comparing Low- or Standard-Dose Alteplase in Endovascular Thrombectomy: Insights From a Nationwide Registry
Stroke Journal
FEBRUARY 5, 2024
The outcomes included successful reperfusion (modified Thrombolysis in Cerebral Infarction score, 2b–3), symptomatic intracerebral hemorrhage, 90-day modified Rankin Scale score, and 90-day mortality. 0.98]), a numerically higher incidence of symptomatic intracerebral hemorrhage (6.7% versus 3.9%; adjusted odds ratio, 1.81 [95% CI, 0.88–3.69]),
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75 Antiplatelet Agent Use After Stroke due to Intracerebral Hemorrhage
Stroke Journal
NOVEMBER 2, 2023
Therefore, ASPIRING (Antiplatelet Secondary Prevention International Randomized Study After Intracerebral Hemorrhage) aims to recruit 4148 ICH survivors to determine the effects of antiplatelet agents after ICH definitively overall and in subgroups. 0.87]) and might increase the risk of ICH (rate ratio, 1.67 [95% CI, 0.97–2.90]).
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Abstract TP13: Effectiveness and safety of direct oral anticoagulation vs. warfarin for primary prevention of stroke and bleeding risk among patients with atrial fibrillation.
Stroke Journal
JANUARY 30, 2025
0.97), P=0.02), and hemorrhagic stroke by 57% (OR, 0.43(95%CI: Pooled analysis of primary and secondary endpoints showed that DOAC significantly reduced the risk of stroke or systemic embolism by 18% (OR, 0.82(95%CI: 0.91), P<0.01), stroke by 19% (OR, 0.81(95%CI: 0.56), P<0.01) when compared with warfarin.
Epistaxis Versus Nonepistaxis Bleeding in Anticoagulated Patients With Atrial Fibrillation: Results From the ENGAGE AF‐TIMI 48 Trial
Journal of the American Heart Association
JANUARY 10, 2025
Patients with intracranial hemorrhage during followup were excluded; those with >1 bleeding event were categorized according to their most severe event. Bleeds were adjudicated using International Society on Thrombosis and Haemostasis criteria.
Abstract 165: Subarachnoid Hemorrhage Related to Thoracic Spinal Cord Stimulator Placement
Stroke: Vascular and Interventional Neurology
NOVEMBER 9, 2023
We present a case of subarachnoid hemorrhage (SAH) due to SCS lead migration into the subdural space.MethodsAn 81‐year‐old female patient with a past medical history of heart failure, atrial fibrillation and a mechanical mitral valve, presents with a severe headache and right hemiparesis.
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What is this ECG finding? Do you understand it before you hear the clinical context?
Dr. Smith's ECG Blog
FEBRUARY 2, 2024
Written by Pendell Meyers First try to interpret this ECG with no clinical context: The ECG shows an irregularly irregular rhythm, therefore almost certainly atrial fibrillation. After an initially narrow QRS, there is a very large abnormal extra wave at the end of the QRS complex. There is also large T wave inversion and long QT.
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138 Abstract TP186: The Presence of Low Signal on T2*-Weighted Gradient Echo Magnetic Resonance Imaging Before MT Should Be Not Associated With Hemorrhagic Complications
Stroke Journal
FEBRUARY 1, 2024
We compared hemorrhagic change after MT, outcome at discharge and clinical characteristics between two groups. We compared hemorrhagic change after MT, outcome at discharge and clinical characteristics between two groups. The occurrence of hemorrhagic change was assessed on CT after MT.
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Abstract 4141940: Outcomes in Middle Eastern Atrial Fibrillation Patients with Prior Ischemic Stroke/Systemic Embolism: Findings from the JoFib Study
Circulation
NOVEMBER 11, 2024
Patients with a history of prior hemorrhagic stroke were excluded from this analysis. Circulation, Volume 150, Issue Suppl_1 , Page A4141940-A4141940, November 12, 2024.
Abstract 091: Intraventricular milrinone for management of vasospasm following aneurysmal subarachnoid hemorrhage
Stroke: Vascular and Interventional Neurology
NOVEMBER 9, 2023
IntroductionAneurysmal subarachnoid hemorrhage (aSAH) accounts for about 10% of hemorrhagic strokes [1] and holds a high mortality and morbidity rate. [2, Head CT on arrival showed a diffuse subarachnoid hemorrhage, more prominent in the posterior fossa, and grade IV on the modified Fisher scale.
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40 Abstract WP144: Early Initiation of Anticoagulation is Safe After Ischemic Stroke With Atrial Fibrillation, Meta-Analysis and Systemic Review
Stroke Journal
FEBRUARY 1, 2024
Background:Large randomized clinical trials have established the superiority of Direct oral anticoagulants (DOACs) over Vitamin-K antagonists in atrial fibrillation (AF) related to Acute Ischemic stroke (AIS). The outcomes of interest were Intracranial hemorrhage (ICH), ischemic stroke & all-cause mortality.
Abstract WP11: The Safety of Emergent Anticoagulation in Acute Ischemic Stroke in Non-Atrial Fibrillation Indications: A Retrospective Analysis
Stroke Journal
FEBRUARY 1, 2024
Introduction:Patients with acute ischemic stroke (AIS) often present with conditions that require emergent anticoagulation (AC) other than atrial fibrillation (AF). The primary outcome was the incidence of intracranial hemorrhage (ICH) between both groups. Stroke, Volume 55, Issue Suppl_1 , Page AWP11-AWP11, February 1, 2024.
Ep 117 TIA Update – Risk Stratification, Workup and Dual Antiplatelet Therapy
ECG Cases
NOVEMBER 20, 2018
The post Ep 117 TIA Update – Risk Stratification, Workup and Dual Antiplatelet Therapy appeared first on Emergency Medicine Cases.
Abstract WMP80: 20 Year Incidence and Outcomes for Intracerebral Hemorrhage During Pregnancy: A Nationwide Study
Stroke Journal
FEBRUARY 1, 2024
Introduction:Pregnant patients are at risk of neurological complications including intracerebral hemorrhage (ICH). vs 63.38, p<0.001) and had fewer comorbidities such as cancer and chronic kidney disease, atrial fibrillation, hypertension, hyperlipidemia. We observed an increasing trend of ICH among pregnant individuals.
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40 Correction to: Early Versus Late Initiation of Direct Oral Anticoagulants After Ischemic Stroke in People With Atrial Fibrillation and Hemorrhagic Transformation: Prespecified Subanalysis of the Randomized Controlled ELAN Trial
Circulation
JUNE 30, 2024
Circulation, Volume 150, Issue 1 , Page e20-e20, July 2, 2024.
PO-03-047 SEVERITY OF ISCHEMIC STROKE POST PERCUTANEOUS LEFT ATRIAL APPENDAGE CLOSURE: NATIONWIDE ANALYSIS
HeartRhythm
APRIL 30, 2024
Percutaneous Left atrial appendage closure (pLAAC) presents an alternative to anticoagulation (AC) for stroke prophylaxis in atrial fibrillation (Afib) patients with high bleeding risk. pLAAC was associated with lower rates of disabling stroke which was mainly attributed to the reduction of hemorrhagic stroke.
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40 Abstract TMP78: Disparities in Experiencing Major Adverse Cardiovascular Events Among Survivors of Spontaneous Intracerebral Hemorrhage by Hematoma Location
Stroke Journal
FEBRUARY 1, 2024
Patients with atrial fibrillation had a higher risk of AIS (1.47, 1.18 - 1.84) and MACE (1.26, 1.07 - 1.49). Medicare) have a lower risk of r-ICH (0.45, 0.31 - 0.67), AIS (0.71, 0.53 - 0.95), and MACE (0.58, 0.47 - 0.71). Patients from low-income zip codes have a higher risk of AMI (1.83, 1.23 - 2.15) and MACE (1.16, 1.02 - 1.32).
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40 Changing or Retaining Direct Oral Anticoagulant After Ischemic Stroke Despite Direct Oral Anticoagulant Treatment
Journal of the American Heart Association
JANUARY 31, 2024
BackgroundThe optimal antithrombotic strategies for patients with atrial fibrillation who experience ischemic stroke (IS) despite direct oral anticoagulant (DOAC) therapy remain inconclusive. The secondary outcomes included intracranial hemorrhage, major bleeding, systemic thromboembolism, and all‐cause death. versus 0.53
InterAtrial Block
EMS 12-Lead
AUGUST 25, 2024
MRI Brain demonstrated Left MCA acute/subacute infarct, MCA/PCA watershed, and no hemorrhagic transformation. And since common things are common, the statistical probability favors Atrial Fibrillation (AFib) as the culprit. Here is the admission ECG. We do have the ECG. But the ECG is Sinus! AFib can come and go.
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Cryptogenic ischemic stroke in cardiac transthyretin amyloidosis and sinus rhythm: a case report
Frontiers in Cardiovascular Medicine
MAY 12, 2024
Among the complications of transthyretin amyloidosis there are thrombotic events and, to a lesser extent, hemorrhagic events. The onset of thrombotic events may be caused by the high prevalence of atrial fibrillation (AF), mechanical cardiac dysfunction and atrial myopathy observed in patients with transthyretin amyloidosis.
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Abstract TP312: Retrospective Analysis of Perioperative Stroke in Patients with Glioma
Stroke Journal
JANUARY 30, 2025
Stroke within 30 days of surgical resection was identified based on the radiology read of MRI brain for ischemic stroke and CT brain for hemorrhagic stroke that was obtained as part of clinical care. Of these, 13 (65%) had ischemic strokes, 7 (35%) had hemorrhagic strokes. Patients who had a stroke were older [mean (SD); 60.4
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Abstract 4141052: Rare Combo: An Unusual Case of a 54-year-old Filipino with Coronary Artery Fistula from Left Anterior Descending Artery to Main Pulmonary Artery and Acute Cerebellar Infarct: A Cardio – Cerebral Infarction Syndrome - Case Report
Circulation
NOVEMBER 11, 2024
Among these, a fistula between the left anterior descending artery and the pulmonary artery is the rarest variant, comprising about 17% of all coronary artery fistula cases.Case:A 54-year-old male, with a known history of atrial fibrillation and hypertension, presented to our emergency department with non-rotatory dizziness.
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Abstract WP279: Predicting Stroke in Patients with Infective Endocarditis: A Comprehensive Systematic Review and Meta-Analysis of Risk Factors
Stroke Journal
JANUARY 30, 2025
Introduction:Neurological complications in patients with infective endocarditis (IE), such as ischemic and hemorrhagic stroke, are well-described, serious complications of IE; however, predicting which patients are most likely to experience stroke remains uncertain. Stroke, Volume 56, Issue Suppl_1 , Page AWP279-AWP279, February 1, 2025.
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40 Relation Between Stroke and Heart Disease
All About Cardiovascular System and Disorders
APRIL 21, 2024
Another type of heart disease which leads to stroke is an abnormal rhythm of the heart known as atrial fibrillation. In atrial fibrillation, there is a fast irregular rhythm originating in the upper chambers of the heart. Rate in the upper chambers is much higher than that in the lower chambers in atrial fibrillation.
Cardiovascular Management in Asymptomatic (Silent) Cerebral Microbleeds and Suspected Cerebral Amyloid Angiopathy
Stroke Journal
MARCH 11, 2024
Historically, the research literature overwhelmingly emphasized the future hemorrhagic risk associated with CMBs, potentially leading to unnecessary withholding of treatments proven effective at preventing thrombosis, such as anticoagulants in patients with atrial fibrillation who happened to have some microbleeds.
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40 Abstract WP23: Hemorrhagic Transformation Following Anticoagulation in Victims of Acute Ischemic Stroke Secondary to Intra-Cardiac Thrombi
Stroke Journal
FEBRUARY 1, 2024
Introduction:Hemorrhagic transformation (HT) following acute ischemic stroke (AIS) is a common consideration especially when therapeutic anticoagulation is indicated in cases such as left ventricular or left atrial appendage thrombi.
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