HeartRhythm

APRIL 30, 2024

Atrial fibrillation is the most prevalent sustained cardiac arrhythmia and an important risk factor for ischemic stroke resulting in a fivefold increased stroke risk. The clinical utility of polygenic risk scores for ischemic stroke prediction among atrial fibrillation patients has not yet been established.

Atrial Fibrillation 40

Atrial Fibrillation Genetic predisposition Stroke Strokes 40

HeartRhythm

NOVEMBER 5, 2024

Atrial fibrillation (AF) is the most common arrhythmia in the U.S., Data pertaining to the American Heart Association Life’s Simple 7 (LS7) health metrics show that Black Americans have suboptimal LS7 scores compared to White Americans on average despite lower genetic predisposition to AF.

Atrial Fibrillation 40

Atrial Fibrillation Risk Factors Genetic predisposition Outcomes 40

Heart BMJ

APRIL 15, 2024

Background The relationship between combined genetic predisposition and lifestyle and the risk of incident atrial fibrillation (AF) is unclear. Therefore, we aimed to assess a possible interaction between lifestyle and genetics on AF risk.

Atrial Fibrillation 52

Atrial Fibrillation Genetic predisposition Risk Factors Diet 52

Journal of the American Heart Association

MARCH 13, 2025

BackgroundClinical and genetic predispositions are significant in predicting atrial fibrillation (AF); however, their role in patients with hypertrophic cardiomyopathy (HCM) remains unclear. Journal of the American Heart Association, Ahead of Print.

Atrial Fibrillation 45

Atrial Fibrillation Risk Factors Cardiomyopathy Genetic predisposition 45

Circulation: Arrhythmia and Electrophysiology

MARCH 5, 2024

BACKGROUND:An association between sweetened beverages and several cardiometabolic diseases has been reported, but their association with atrial fibrillation (AF) is unclear. The highest HRs (95% CIs) of AF were observed for participants at high genetic risk who consumed >2 L/wk of ASB (HR, 3.51 [95% CI, 2.94–4.19]),

Atrial Fibrillation 40

Atrial Fibrillation Genetic predisposition Diet Electrophysiology 40

Frontiers in Cardiovascular Medicine

FEBRUARY 14, 2024

Results Our study identified a genetic predisposition associated with an additional 3.6 Causality was assessed using the inverse-variance weighted (IVW), ME-Egger regression, and weighted median methods. Sensitivity analyses, including heterogeneity and pleiotropy tests, were conducted to ensure the robustness of our findings.

Education 49

Education Cardiovascular Disease Peripheral Arterial Disease Genetic predisposition 49

MIBHS

FEBRUARY 28, 2025

Heart disease remains one of the leading causes of death worldwide, often attributed to a mix of lifestyle choices, environmental factors, and genetic predispositions. Familial Hypercholesterolemia (FH): FH is a genetic disorder resulting in high LDL cholesterol levels from an early age, significantly raising the risk of heart attacks.

Genetic predisposition 52

Genetic predisposition Heart Disease Cholesterol Blood Pressure 52