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Study Demonstrates Abelacimab Significantly Reduced Bleeding in Patients Regardless of Age, Bleeding Risk

DAIC

Patients with atrial fibrillation, particularly older patients, are frequently at a high risk of bleeding. Ruff, MD, MPH, senior investigator of TIMI Group, director General Cardiology, Brigham and Women's Hospital, and associate professor, Harvard Medical School. in the low risk category to 21.2%

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Study Shows Abelacimab Significantly Reduced Bleeding vs. Standard DOAC

DAIC

Affecting 60 million people worldwide 1 , the prevalence of atrial fibrillation (AFib) is expected to increase by 60% by 2050 due to an aging population and rising cardiometabolic risk factors 2. In addition, the Centers for Disease Control and Prevention (CDC) estimates that more than 12 million Americans will have AFib by 2030 3.

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Potential Risk of Serious Bleeding in Patients With AF Using Diltiazem With Apixaban or Rivaroxaban

All About Cardiovascular System and Disorders

A potentially serious drug interaction between diltiazem and apixaban or rivaroxaban has been reported in US Medicare patients taking these drugs together for atrial fibrillation. The study compared serious bleeding risk for new users of apixaban or rivaroxaban with atrial fibrillation treated with diltiazem or metoprolol.

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ARCADIA Trial on Atrial Cardiopathy and Stroke

All About Cardiovascular System and Disorders

In an earlier post on Embolic Stroke of Undetermined Source (ESUS) , I had mentioned about ARCADIA trial (AtRial Cardiopathy and Antithrombotic Drugs In Prevention After Cryptogenic Stroke) which was testing whether there is role for apixaban compared to aspirin for prevention of recurrent stroke in ESUS.

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Brugada Syndrome: Diagnosis and Risk Stratification

All About Cardiovascular System and Disorders

They include myocardial ischemia, acute pericarditis, pulmonary embolism, external compression due to mass over the right ventricular outflow tract region, and metabolic disorders like hyper or hypokalemia and hypercalcemia. Atrial fibrillation and Brugada syndrome. mV or R/q ≥ 0.75. Heart Rhythm. 2016 Oct;13(10):e295-324.

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Hypertrophic Cardiomyopathy

All About Cardiovascular System and Disorders

Left ventricular hypertrophy, left atrial enlargement, QRS axis deviation (left more than right), conduction abnormalities like increased P-R interval and bundle branch block may be noted. Mid cavity obstruction in HCM is associated with apical aneurysm, systemic embolism, and arrhythmias. Doppler echo showing LVOT gradient in HCM.