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Calpain inhibition takes center stage against atrial fibrillation in the diabetic heart

HeartRhythm

Diabetes mellitus (DM) is a public health problem that continues to grow worldwide. 1 Atrial fibrillation (AF) is the most common cardiac arrhythmia, affecting more than 6 million individuals in the United States.2 In the United States the Center for Disease Control and Prevention estimates that it affects 11.6%

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Rate vs Rhythm Control in Atrial Fibrillation

All About Cardiovascular System and Disorders

Rate vs Rhythm Control in Atrial Fibrillation Rate vs rhythm control as a management strategy in atrial fibrillation has been a long standing topic for debate. EAST-AFNET 4 trial had 2789 patients with early atrial fibrillation and cardiovascular conditions [8]. years of follow up per patient. N Engl J Med.

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AFib Might Be Far More Common Than We Think

CardiacWire

A JACC study suggests that atrial fibrillation is far more prevalent than many previously thought, estimating that nearly one in 20 American adults have been diagnosed with the disease. That increase was greatest among younger patients, males, minorities, and patients with hypertension and diabetes. adult population.

AFIB 105
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Abstract 4122350: Most Diabetes Mellitus Patients Had Right Lower Pulmonary Vein Thrombi; Additionally, Many Patients Had Extended Large Rod-Like Thrombi in the Left Atrium

Circulation

of senior patients with age-related diseases such as hypertension, dyslipidemia and atrial fibrillation had PVTs, as estimated by cardiac computed tomography (CT) and transesophageal echocardiography (TEE). Patients with type 2 diabetes mellitus (T2DM) must have PVTs. In 2022, we reported that 98.6% from 50 y.o.

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Challenges in the Cardiovascular Evaluation and Management of Patients With Obesity

American College of Cardiology

Obesity is a multifaceted disease that is directly and indirectly implicated in atherosclerotic cardiovascular disease (CVD), heart failure (HF), atrial fibrillation (AF), and multiple CVD risk factors, including dyslipidemia, hypertension, type 2 diabetes mellitus (DM), and sleep disorders.

Obesity 71
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America’s Growing CVD Problem

CardiacWire

Heart Disease in 2050 – The AHA warned of massive heart disease increases by 2050, spanning CVD (+60%), diabetes (+100%), obesity (+70%), hypertension (+44%), heart failure (+66%), and stroke (+100%). Hypertension Problems: Another JAMA study highlighted the U.S.’s s massive hypertension diagnosis and treatment problems.

AFIB 59
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Right ventricular function and anemia in heart failure with preserved ejection fraction

Frontiers in Cardiovascular Medicine

Multivariate linear regression analysis shows that the degree of anemia, atrial fibrillation, and TR were independently associated with the TAPSE/PASP ratio.ConclusionAnemia in HFpEF is associated with RV dysfunction, and this relationship is not affected by classical risk factors, such as smoking, hypertension, and diabetes.