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Mechanisms and potential targets to manage atrialfibrillation related to diabetes mellitus are represented. ABSTRACT In spite of significant progress made in the management in recent decades, atrialfibrillation (AF) continues to cause increased mortality and significant morbidities, including heart failure and stroke.
A JACC study suggests that atrialfibrillation is far more prevalent than many previously thought, estimating that nearly one in 20 American adults have been diagnosed with the disease. UCSF researchers analyzed medical records from 29M adults who received hospital-based care in California from 2005 to 2019 (51yr avg.
ABSTRACT Atrialfibrillation (AF) is the most common cause of arrhythmia-induced cardiomyopathy. Sodium-glucose co-transporter 2 inhibitors (SGLT2i), a novel class of antidiabetic drugs, have shown a promising impact in reducing cardiovascular events in diabetic and nondiabetic heart failure (HF) patients.
BackgroundThe clinical utility of the polygenic risk score in predicting cardiovascular events in patients with atrialfibrillation (AF) has not yet been established. years), the incidence rates of ischemic stroke or systemic embolism, myocardial infarction, and heart failure hospitalization were 0.83, 0.42, and 0.61
Introduction:Clinical characteristics of patients with in-hospital onset stroke (IHOS) compared to those with out-of-hospital onset stroke are reported to be late detection of stroke onset, less use of rt-PA, presence of atrialfibrillation, and poor outcome. were male) were enrolled into this study.
Background Out-of-hospital cardiac arrest (OHCA) has a dismal prognosis with overall survival around 10%. The most common comorbidities prior to OHCA were hypertension (43.6%), heart failure (23.6%), chronic ischaemic heart disease (23.6%) and atrialfibrillation (22.0%). had type 2 diabetes, compared with 19.6%
Background:Clinical studies on atrialfibrillation (AF) recurrence after catheter ablation in patients diagnosed with patent foramen ovale (PFO) and paroxysmal AF (PAF) are scarce. The constructed nomogram included four clinical variables: age, diabetes mellitus, lipoprotein (a), and right ventricular diameter.
Getty Images milla1cf Fri, 12/08/2023 - 08:17 December 8, 2023 — The American College of Cardiology (ACC) and the American Heart Association (AHA), along with several other leading medical associations, have issued a new guideline for preventing and optimally managing atrialfibrillation (AFib).
ABSTRACTAtrial fibrillation (AF) is the most common cardiac arrhythmia. AF increases the risk of stroke, heart failure, dementia, and hospitalization. Obesity significantly increases AF risk, both directly and indirectly, through related conditions, like hypertension, diabetes, and heart failure.
Introduction:The transitional period from hospital discharge to the community for stroke survivors is a vulnerable time as patients navigate healthcare systems with their new impairments. The intervention group had a significantly lower rate of 1 year hospital readmission due to any cause (62.1% vs 69.3%, p=0.04).
Multivariate regression revealed that patients with anleft atrial LA diameter of > 4& cm (AOR 2.531, P = 0.003), patients who did not take B-blockers before surgery (AOR 1.1
Background:The STRACK project aims to improve post-stroke patient management and the transition from acute to primary care thanks to improvements in patient pathways and monitoring cardiovascular risk factors: heart failure, diabetes, atrialfibrillation, dyslipidemia and hypertension.
Data was obtained from the Hospital Corporation of America (HCA) enterprise-wide database from January 2020 to September 2023 using the International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM).
Introduction:Effective care transition for ischemic or hemorrhagic stroke patients post-hospital discharge is critical. Ensuring a follow-up neurology appointment within two weeks is vital to managing stroke risk factors like hypertension, diabetes, and atrialfibrillation.
Exclusion criteria were pregnancy, lactation, intracerebral hemorrhage, atrialfibrillation, left ventricular clot, and cardioembolic stroke. Significant associations were found between recurrent ischemic events and hypertension (p=0.001), diabetes (p=0.033), and smoking (p=0.001). Data were collected from medical records.
Background:Current prevalence estimates of heart failure (HF) are primarily based on self-report or HF hospitalizations. The prevalence of HF risk factors was high: hypertension, 61.9%; former or current smoking, 53.7%; obesity 34.8%; diabetes; 24.7%; and chronic kidney disease; 22%. Circulation: Heart Failure, Ahead of Print.
We aimed to examine the prevalence of VRFs and temporal trends in VRF burden among young patients presenting with IS.Methods:Data was prospectively collected by Get With the Guidelines-Stroke® hospitals participating in the Florida Stroke Registry between January 2010 and December 2022.
A prior history of the following comorbidities was considered: episodic or persistent atrialfibrillation ( n = 920), coronary artery disease ( n = 3732), diabetes ( n = 2171), and hypertension ( n = 3353). Patients were classified into three groups based on the number of comorbidities: 0, 1–2, or ≥3.
CT scan before discharge showed mild improvement in ventricular size and stable SAH blood products.The course of hospitalization was complicated by hyponatremia, atrialfibrillation, and respiratory failure with inability to wean off ventilator, resulting in tracheostomy and gastrostomy tube placement.
The patient underwent surgery, but suffered from a gastrointestinal bleed and developed post‐operative atrialfibrillation; after a risks/benefits discussion, he was discharged on anticoagulation only. Episodes always occurred after activity and only upon sitting.
Case submitted and written by Mazen El-Baba MD, with edits from Jesse McLaren and edits/comments by Smith and Grauer A 90-year old with a past medical history of atrialfibrillation, type-2 diabetes, hypertension, dyslipidemia, presented with acute onset chest/epigastric pain, nausea, and vomiting.
In-hospital mortality was defined as a Modified Rankin Scale (mRS) score of 6 point. Multifactorial logistic regression analyses using fully adjusted models, demonstrated that the SII is independently associated with the risk of in-hospital death. Notably, the combined model outperformed the SII alone (P<0.05).
Rate vs Rhythm Control in AtrialFibrillation Rate vs rhythm control as a management strategy in atrialfibrillation has been a long standing topic for debate. EAST-AFNET 4 trial had 2789 patients with early atrialfibrillation and cardiovascular conditions [8]. years of follow up per patient.
Objective Red cell distribution width (RDW) and serum calcium (Ca) levels are predictors of in-hospital mortality in acute myocardial infarction (AMI) patients. Therefore, this study aimed to determine whether the RDW to Ca ratio (RCR) acquired on admission can be used to predict the in-hospital mortality of AMI patients.
We collected blood from each patient at hospital admission before administering any therapeutic intervention. After adjusting for age, sex, diabetes, and coronary artery disease in the multivariable analysis, we identified 53 top proteins independently associated with AFib in stroke patients (adjusted p<0.05) (Figure 2).
I’ve worked with hospitals, provider groups and payers – trying to help drive the right type of access, care, and value across the healthcare continuum. 1 That problem is exacerbated by the lack of access to acute care: Since 2011, two-thirds of the hospital closures in the U.S. have been in rural areas.
Written by Magnus Nossen The patient in today's case is a male in his 70s with hypertension and type II diabetes mellitus. The rhythm now is atrialfibrillation. He was later transferred back to his local hospital neurologically intact and without serious sequela. In the initial ECG (ECG# 1) aVR had ST elevation.
Researchers analyzed more than 145 million records covering every adult patient admitted to hospital in England over a nine-year period to establish the risk of long-term health outcomes following a heart attack -- in the largest study of its kind.
Association between clusters and the composite of (i) heart failure hospitalization or all-cause death, (ii) cardiovascular (CV) hospitalization or all-cause death, and (iii) major adverse CV events was assessed. Finally, the reproducibility of the results of cluster analysis is tested in an external cohort (validation set).
Getty Images milla1cf Wed, 06/26/2024 - 18:59 June 26, 2024 — Semaglutide , a medication initially developed for type 2 diabetes and obesity, significantly improves symptoms in men and women with a common type of heart failure that has had few therapeutic options.
However, the short-term risk of stroke, particularly within 90 days of hospitalization, has not been thoroughly evaluated on a national scale. Significant interactions were observed with age, sex, hypertension, and atrialfibrillation (Figure).Conclusions:In 1.99, p < 0.001). 1.23, p=0.846).
ARIES-HM3 Subgroup Analysis: Nir Uriel, MD (USA) presented findings from a subgroup analysis of ARIES-HM3, showing that avoiding aspirin in newly implanted HeartMate 3 LVAD patients with atrialfibrillation, diabetes, and obesity significantly reduces non-surgical bleeding events at one year while maintaining safety.
Adjusted analyses (Cox proportional hazard ratios) illustrate a higher risk of heart failure hospitalization (HFH) and all-cause mortality (ACM) after a median follow-up of 18months in patients with heart failure and iron deficiency (ID) as assessed by transferrin saturation (TSAT) <20% and iron 13 mol/L.
Hypertension was a common co‐morbidity in half of the population, also diabetes and atrialfibrillation were existing in 1/3 of cases. The mean age was 65 with a male to female ratio of 6:5. On long term follow‐up at 90 days post ictus, 24% (n=14) had favorable outcome of MRS 0‐2.
Patient- and hospital-level characteristics were analyzed. Outcomes included favorable disposition (discharged to home) and in-hospital mortality.Results:Among 68,975 of stroke MT with recorded NIHSS during the study period (51.1% In-hospital mortality occurred in 17.1% women; mean age, 69.1 [SD, of MT with stenting versus 32.3%
mg/kg) were reviewed from 21 hospitals in a large integrated health system between November 2020 to December 2023. of patients, followed by diabetes (58%), hyperlipidemia (55%), atrialfibrillation (20%), and history of stroke (18%). Results:The mean age of the 195 cases was 75.4 (SD SD = 13.46).
Factors considered in analysis include patient age, sex, geographic region, Medicaid dual eligibility, disability status prior to age 65, comorbidities, admission length of stay, discharge disposition, and hospital characteristics. 1.378]), and heart failure (1.282 [95%CI, 1.25‐1.315]).ConclusionPatient
We used a mixed effects linear regression model to examine the relationship between DTD group and length of stay, controlling for age, race, sex, last known well to arrival time, initial NIHSS, atrialfibrillation, and alcohol/drug abuse and clustering by hospital site.
Just for clarity, type 2 diabetes is when insulin resistance progresses to the point that your body can no longer keep your blood glucose levels under control. So if you have type 2 diabetes, you, by definition, are insulin resistant. Assessing fasting insulin can be tricky and often needs to be done in a major hospital lab setting.
Additionally, CM‐HF patients had higher rates of medical comorbidities such as atrialfibrillation (43.6% 24.2%, p < 0.001), diabetes mellitus (39.7% 44.9%, p < 0.001) and short‐term hospitalization (2.8% Compared to matched cohorts, CM‐HF patients were more likely to be younger (age <80: 22.4%
The association of GLS with the risk of incident major adverse cardiovascular events (MACE; composite of incident myocardial infarction, incident heart failure [HF], hospitalization for atrialfibrillation, coronary revascularization, and all-cause death), and incident HF or death were assessed with adjusted Cox proportional hazards models.
Methodology:The HFrEF patients’ data were prospectively evaluated during the initial assessment and those hospitalized, and subseguently followed for at least 12months. Sex, age and racial/ethnic disparities, in-hospital management, follow-ups, health status and 1year mortality were assessed.
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