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Diabetes and Atrial Fibrillation: Insight From Basic to Translational Science Into the Mechanisms and Management

Journal of Cardiovascular Electrophysiology

Mechanisms and potential targets to manage atrial fibrillation related to diabetes mellitus are represented. ABSTRACT In spite of significant progress made in the management in recent decades, atrial fibrillation (AF) continues to cause increased mortality and significant morbidities, including heart failure and stroke.

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AFib Might Be Far More Common Than We Think

CardiacWire

A JACC study suggests that atrial fibrillation is far more prevalent than many previously thought, estimating that nearly one in 20 American adults have been diagnosed with the disease. UCSF researchers analyzed medical records from 29M adults who received hospital-based care in California from 2005 to 2019 (51yr avg.

AFIB 105
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Impact of Sodium‐Glucose Co‐Transporter 2 Inhibitors on Atrial Fibrillation Recurrence Post‐Catheter Ablation Among Patients With Type 2 Diabetes Mellitus: A Systematic Review and Meta‐Analysis

Journal of Cardiovascular Electrophysiology

ABSTRACT Atrial fibrillation (AF) is the most common cause of arrhythmia-induced cardiomyopathy. Sodium-glucose co-transporter 2 inhibitors (SGLT2i), a novel class of antidiabetic drugs, have shown a promising impact in reducing cardiovascular events in diabetic and nondiabetic heart failure (HF) patients.

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Polygenic Risk and Cardiovascular Event Risk in Patients With Atrial Fibrillation With Low to Intermediate Stroke Risk

Journal of the American Heart Association

BackgroundThe clinical utility of the polygenic risk score in predicting cardiovascular events in patients with atrial fibrillation (AF) has not yet been established. years), the incidence rates of ischemic stroke or systemic embolism, myocardial infarction, and heart failure hospitalization were 0.83, 0.42, and 0.61

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Abstract TP254: The Incidence Rate and Risk Factors of In-Hospital Onset Stroke Among 83,990 Hospitalized Patients

Stroke Journal

Introduction:Clinical characteristics of patients with in-hospital onset stroke (IHOS) compared to those with out-of-hospital onset stroke are reported to be late detection of stroke onset, less use of rt-PA, presence of atrial fibrillation, and poor outcome. were male) were enrolled into this study.

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Comorbidities prior to out-of-hospital cardiac arrest and diagnoses at discharge among survivors

Open Heart

Background Out-of-hospital cardiac arrest (OHCA) has a dismal prognosis with overall survival around 10%. The most common comorbidities prior to OHCA were hypertension (43.6%), heart failure (23.6%), chronic ischaemic heart disease (23.6%) and atrial fibrillation (22.0%). had type 2 diabetes, compared with 19.6%

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The Impact of SGLT2 Inhibitors on Atrial Fibrillation Recurrence and Long‐Term Clinical Outcomes in HFrEF Patients Undergoing Cryoballoon Ablation: A New Frontier Beyond Diabetes and Heart Failure

Journal of Cardiovascular Electrophysiology

ABSTRACT Background Atrial fibrillation (AF) recurrence remains a significant challenge in heart failure with reduced ejection fraction (HFrEF) patients undergoing cryoballoon ablation (CBA). Secondary endpoints included all-cause mortality and heart failure (HF)-related hospitalizations. vs. 39.4%, p =0.036). Mortality (9.9%