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Background We evaluated the potential of circulating bone morphogenetic protein 10 (BMP10) as a biomarker for atrial stress and remodelling in patients with heart failure (HF), in comparison to N-terminal pro-B-type natriuretic peptide (NT-proBNP). We also assessed the predictive value of BMP10 for adverse clinical outcomes.
Patients who present with persistent atrialfibrillation at diagnosis are more likely to have certain riskfactors as compared with patients with occasional atrialfibrillation (AFib).
Circulation, Ahead of Print. to 6.4%), atrialfibrillation (1.7% BACKGROUND:Cardiovascular disease and stroke are common and costly, and their prevalence is rising. in 2020 to 61.0% The prevalences of poor diet, inadequate physical activity, and smoking are estimated to improve over time, whereas inadequate sleep will worsen.
The increasing prevalence of atrialfibrillation (AF) in adults with congenital heart disease raises significant questions regarding its management. Journal of the American Heart Association, Ahead of Print. Emerging imaging modalities and ablation techniques might have a role to play.
Circulation, Ahead of Print. Recommendations from the “2014 AHA/ACC/HRS Guideline for the Management of Patients With AtrialFibrillation” and the “2019 AHA/ACC/HRS Focused Update of the 2014 AHA/ACC/HRS Guideline for the Management of Patients With AtrialFibrillation” have been updated with new evidence to guide clinicians.
Objective:Forward head posturing (FHP) has been associated with chronic anatomic vertebral artery disturbances possibly leading to posterior circulation ischemia. The data supporting FHP as a true riskfactor of posterior circulation stroke has not been well established. The average C2 tilt of cases was 22.9
Circulation, Ahead of Print. The human capital approach was used to estimate productivity losses from morbidity and premature mortality due to cardiovascular conditions.RESULTS:One in 3 US adults received care for a cardiovascular riskfactor or condition in 2020.
Titled "Real-world Data Affirms Safety and Effectiveness of Low/Zero Fluoroscopy AtrialFibrillation Ablation," the study was presented as a late-breaker at the 29th Annual International AF Symposium. Real-world Data Affirms Safety and Effectiveness of Low/Zero Fluoroscopy AtrialFibrillation Ablation [abstract].
A projected rise in heart disease and stroke – along with several key riskfactors, including high blood pressure and obesity – is likely to triple related costs to $1.8 trillion by 2050, according to two presidential advisories published in the AHA journal Circulation. Obesity rates are expected to climb from 43.1%
Circulation, Volume 150, Issue Suppl_1 , Page A4148106-A4148106, November 12, 2024. Owing to improved management, the life expectancy of patients with hemophilia has increased significantly and predisposes them to risk of cardiovascular diseases and thrombotic events. The hemophilia cohort was slightly older (63.2[16.8]
Getty Images milla1cf Fri, 12/08/2023 - 08:17 December 8, 2023 — The American College of Cardiology (ACC) and the American Heart Association (AHA), along with several other leading medical associations, have issued a new guideline for preventing and optimally managing atrialfibrillation (AFib). Additional Resources: After Nov.
Circulation, Volume 150, Issue Suppl_1 , Page A4141066-A4141066, November 12, 2024. Background:Clinical studies on atrialfibrillation (AF) recurrence after catheter ablation in patients diagnosed with patent foramen ovale (PFO) and paroxysmal AF (PAF) are scarce.
Circulation: Arrhythmia and Electrophysiology, Ahead of Print. BACKGROUND:The strongest genetic riskfactors for atrialfibrillation (AF) are DNA variants on chromosome 4q25 near the transcription factor genePITX2.
Circulation, Volume 150, Issue Suppl_1 , Page A4147213-A4147213, November 12, 2024. Introduction:Stroke prevention with anticoagulation is an important aspect of atrialfibrillation (AF) management. Anticoagulation is often based on the premise that the risk of stroke increases with each additional CHA2DS2VASc riskfactor.
Circulation: Arrhythmia and Electrophysiology, Ahead of Print. BACKGROUND:An association between sweetened beverages and several cardiometabolic diseases has been reported, but their association with atrialfibrillation (AF) is unclear.
Circulation, Volume 150, Issue Suppl_1 , Page A4137989-A4137989, November 12, 2024. Background:A bimodal P wave in lead II reflects left atrial remodeling and is described as a notched P wave. A notched P wave is also known to predict atrialfibrillation (AF) after catheter ablation.
Detection of Irregular Heart Rhythms Devices such as the Apple Watch or Fitbit Sense can detect irregular heart rhythms, including atrialfibrillation (AFib). These early warnings are critical, as AFib increases the risk of stroke and other heart-related complications.
Circulation, Volume 150, Issue Suppl_1 , Page A4143007-A4143007, November 12, 2024. This study focuses on the correlation between FAI and the morbidity of new-onset atrialfibrillation (NOAF) in MINOCA patients.Methods:This study was a single-center, observational clinical cohort study.
In general, riskfactors for stroke and some forms of heart disease are similar. These clots can break away into the circulation and get lodged into a blood vessel of the brain. Another type of heart disease which leads to stroke is an abnormal rhythm of the heart known as atrialfibrillation.
Circulation, Ahead of Print. Hematopoietic stem cell transplantation can cure various disorders but poses cardiovascular risks, especially for elderly patients and those with cardiovascular diseases. In adults, arrhythmias such as atrialfibrillation and flutter are the most frequent acute cardiovascular complication.
Circulation: Heart Failure, Ahead of Print. The prevalence of HF riskfactors was high: hypertension, 61.9%; former or current smoking, 53.7%; obesity 34.8%; diabetes; 24.7%; and chronic kidney disease; 22%. Overt cardiovascular disease, which ranged from 2.1% (HF) to 13.6% (atrialfibrillation), was less common.
While traditional vascular riskfactors (eg, hypertension, dyslipidemia, tobacco use) account for 20% of the explained variance in carotid atherosclerosis, they remain a prominent focus for primary and secondary ischemic stroke prevention strategies. Stroke: Vascular and Interventional Neurology, Ahead of Print.
Introduction:Carotid artery webs are a rare cause of embolic stroke of undetermined source, especially among the young without conventional riskfactors. Stroke, Volume 55, Issue Suppl_1 , Page ATMP66-ATMP66, February 1, 2024. However, despite its detriment, the rate of stroke recurrence is not well studied.
Circulation, Volume 150, Issue Suppl_1 , Page A4123899-A4123899, November 12, 2024. Medical records were examined for baseline characteristics, riskfactors, and cortical brain infarcts.Results:From 51,732 subjects, 18 were identified with IVMS aneurysms, yielding a prevalence of 0.04%.
The patient underwent surgery, but suffered from a gastrointestinal bleed and developed post‐operative atrialfibrillation; after a risks/benefits discussion, he was discharged on anticoagulation only. Timely diagnosis is imperative, as decompressive surgery can be curative.
Diagnosis : Atrial flutter with 1:1 conduction, with fast AV conduction made possible by sympathetic drive of exercise On arrival, we obtained another 12-lead: Unremarkable Further history: One month history of shortness of breath on exertion, denies palpitations, chest pain, orthopnea, leg swelling. Sinus tachycardia does not go this fast.
2,3 Approximately 1 in 4 adults over the age of 40 are at risk for developing AFib. Global epidemiology of atrialfibrillation: An increasing epidemic and public health challenge. Epidemiology of AtrialFibrillation in the 21st Century. Epidemiology of AtrialFibrillation in the 21st Century.
About AtrialFibrillation and Pulsed Field Ablation AF is one of the most common and undertreated heart rhythm disorders, affecting more than 60 million people worldwide3. 4-7 Current ablation technologies rely on thermal effects to target cardiac tissue and risk damage to additional collateral structures in the heart.
AF Often Asymptomatic: Even for atrialfibrillation (AF)the most commonly symptomatic arrhythmiaover half of all cases were asymptomatic. If left untreated, certain arrhythmias can damage the heart, brain, or other organs 4 and increase the risk of stroke or death. Circulation: Heart Failure. 2016;11(8). doi:10.1161/01.str.22.8.983
Rate vs Rhythm Control in AtrialFibrillation Rate vs rhythm control as a management strategy in atrialfibrillation has been a long standing topic for debate. EAST-AFNET 4 trial had 2789 patients with early atrialfibrillation and cardiovascular conditions [8]. years of follow up per patient.
Heart disease remains one of the leading causes of death worldwide, often attributed to a mix of lifestyle choices, environmental factors, and genetic predispositions. This blog explores how genetics influence heart health and whether mitigating these inherited risks is possible. Can You Prevent Heart Disease if Its in Your Genes?
Circulation, Ahead of Print. BACKGROUND:Oral anticoagulation is suggested in patients with atrialfibrillation and a CHA2DS2-VASc score ≥1 (congestive heart failure, hypertension, age ≥75 years, diabetes, stroke, vascular disease, age 65–74 years, and sex score). Female sex was not considered a riskfactor in any risk group.
Circulation: Arrhythmia and Electrophysiology, Ahead of Print. BACKGROUND:Sustained forms of atrialfibrillation (AF) are associated with lower treatment success rates and poorer prognosis compared with paroxysmal AF. Yet, little is known about riskfactors that predispose to persistent AF on initial presentation.
The real question is what the Tsimane tribe's riskfactor profile looks like. Because if we can understand that, we can attempt to emulate it and also considerably delay the onset of cardiovascular disease and our risk of an early death as a consequence of it. Minimising cardiovascular risk is possible. Circulation.
Circulation: Arrhythmia and Electrophysiology, Ahead of Print. BACKGROUND:Patients undergoing first-time atrialfibrillation (AF) ablation can benefit from targeting non-pulmonary vein (PV) triggers. Preprocedural identification of high-risk individuals can guide planning of ablation strategy.
Circulation: Cardiovascular Quality and Outcomes, Ahead of Print. BACKGROUND:Transcatheter left atrial appendage occlusion (LAAO) is an alternative to oral anticoagulants (OACs) for stroke prevention in patients with atrialfibrillation, but the predictors of LAAO use in routine care are unclear.
Among 475 patients with cardiac sarcoidosis, 119 (25.1%) were isolated cardiac sarcoidosis (iCS) based on the 2016 Japanese Circulation Society criteria. iCS was diagnosed according to the 2016 Japanese Circulation Society (JCS) guidelines. During a median follow-up of 42.3 interquartile range, 22.8–72.5) 2.34; p = 0.011).
Circulation: Heart Failure, Ahead of Print. BACKGROUND:Greater left atrial size is associated with a higher incidence of cardiovascular disease and mortality, but the full spectrum of diagnoses associated with left atrial enlargement in sex-stratified clinical populations is not well known.
Inclusion criteria: anterior circulation occlusion involving the intracranial ICA, MCA‐M1/M2/M3 or ACA(A1‐A2‐A3). Patients with ICAD more frequently presented with vascular riskfactors. ICAD cases were matched for age and sex in a 1:1 ratio to non‐ICAD controls.ResultsA total of 348 patients were included in the analysis.
Circulation, Volume 150, Issue Suppl_1 , Page A4138269-A4138269, November 12, 2024. Background:A broad P wave in electrocardiography reflects atrial remodeling and is associated with cardiovascular events.
Circulation, Volume 150, Issue Suppl_1 , Page A4145926-A4145926, November 12, 2024. Introduction:Excessive dietary salt intake is a recognized ASCVD riskfactor, and causes approximately 1.89 There is also an ongoing discussion whether dietary salt might be associated with the direct ASCVD risk. million deaths annually.
Circulation, Volume 150, Issue Suppl_1 , Page A4137695-A4137695, November 12, 2024. Methods:We studied the impact of BBB in HFpEF utilizing propensity score(PS) matched cohorts without and with BBB from the TOPCAT Americas trial to account for confounding by other co-morbidities.
Circulation: Genomic and Precision Medicine, Volume 17, Issue 6 , Page e004685, December 1, 2024. The association between PGSMDand CAD was consistent between females who were premenopausal and postmenopausal at baseline, while the association with AF and HF was only observed in the baseline postmenopausal cohort.
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