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An analysis of the biomolecule substudy of the EAST–AFNET 4 trial has revealed that biomolecule concentrations in the blood of patients with atrialfibrillation can be used to identify patients at high and low cardiovascular risk. The findings were published in Cardiovascular Research.
Background We evaluated the potential of circulating bone morphogenetic protein 10 (BMP10) as a biomarker for atrial stress and remodelling in patients with heart failure (HF), in comparison to N-terminal pro-B-type natriuretic peptide (NT-proBNP). We also assessed the predictive value of BMP10 for adverse clinical outcomes.
Global epidemiology of atrialfibrillation: An increasing epidemic and public health challenge. Epidemiology of AtrialFibrillation in the 21st Century. Epidemiology of AtrialFibrillation in the 21st Century. Circulation Research. Int J Stroke. 2021 Feb;16(2):217-221. doi: 10.1177/1747493019897870.
About AtrialFibrillation and Pulsed Field Ablation AF is one of the most common and undertreated heart rhythm disorders, affecting more than 60 million people worldwide3. Circulation. Mortality trends in patients diagnosed with first atrialfibrillation: a 21-year community-based study. November 2023.
Circulation. Outcomes of ablation with the FARAPULSE PFA System – a nonthermal treatment in which electric fields selectively ablate heart tissue – will be compared to outcomes following use of anti-arrhythmic drug (AAD) therapy, which is commonly prescribed for patients living with persistent AF.
When atrialfibrillation (AF) begins, it can start with a single focus, degenerating to multiple wavelets, and it spreads throughout the entire surface area of both atria. A fibrillatory wave that occurs at a rate of more than 600 beats per minute can cause fatigue in the long run, leading to atrial dilation.
The increasing prevalence of atrialfibrillation (AF) in adults with congenital heart disease raises significant questions regarding its management. Journal of the American Heart Association, Ahead of Print. Finally, any remaining gaps in knowledge and potential areas of future research are highlighted.
Circulation, Ahead of Print. Recommendations from the “2014 AHA/ACC/HRS Guideline for the Management of Patients With AtrialFibrillation” and the “2019 AHA/ACC/HRS Focused Update of the 2014 AHA/ACC/HRS Guideline for the Management of Patients With AtrialFibrillation” have been updated with new evidence to guide clinicians.
Background Covert atrialfibrillation (AF) is a predominant aetiology of embolic stroke of undetermined source (ESUS). Conclusion Our study showed that posterior circulation infarcts with brainstem/cerebellum involvement are associated with AF detection in ESUS patients undergoing ILR.
Rate vs Rhythm Control in AtrialFibrillation Rate vs rhythm control as a management strategy in atrialfibrillation has been a long standing topic for debate. EAST-AFNET 4 trial had 2789 patients with early atrialfibrillation and cardiovascular conditions [8]. years of follow up per patient. N Engl J Med.
Circulation, Ahead of Print. All findings were qualitatively similar when analyzed across BW.CONCLUSIONS:The treatment effect of NOAC versus warfarin in atrialfibrillation is generally consistent for stroke/SEE across the spectrum of BMI and BW, whereas the reduction in major bleeding is attenuated at a higher BMI and BW.
A JACC study suggests that atrialfibrillation is far more prevalent than many previously thought, estimating that nearly one in 20 American adults have been diagnosed with the disease. That’s far higher than previous estimates, including a pair of JAMA and Circulation studies that estimated nationwide AFib rates of 2.26M and 5.1M
Metabolic remodeling has been recently pointed to play an important role in the pathological process of atrialfibrillation (AF). Ketone bodies (KB) are important cardiac metabolic energy source.
Patients who present with persistent atrialfibrillation at diagnosis are more likely to have certain risk factors as compared with patients with occasional atrialfibrillation (AFib).
Titled "Real-world Data Affirms Safety and Effectiveness of Low/Zero Fluoroscopy AtrialFibrillation Ablation," the study was presented as a late-breaker at the 29th Annual International AF Symposium. Real-world Data Affirms Safety and Effectiveness of Low/Zero Fluoroscopy AtrialFibrillation Ablation [abstract].
AF Often Asymptomatic: Even for atrialfibrillation (AF)the most commonly symptomatic arrhythmiaover half of all cases were asymptomatic. Its estimated that undiagnosed atrialfibrillation alone costs the U.S. $3 Atrialfibrillation as an independent risk factor for stroke: The Framingham Study. 2016;11(8).
After 13 minutes of ALS resuscitation, pulses were palpated indicating a return of spontaneous circulation. Initial vitals show hypertension (175/85), AtrialFibrillation with RVR as seen in Figure 1 , hypercapnia (99mmHg), and SPO2 of 100%. After 5 minutes post-ROSC, the atrialfibrillation converted to a sinus rhythm.
Circulation: Arrhythmia and Electrophysiology, Ahead of Print. BACKGROUND:Atrial fibrillation is the most common cardiac arrhythmia in the world and increases the risk for stroke and morbidity. This finding could have important ramifications for identifying clinically important forms of atrialfibrillation and in guiding treatment.
We aimed to synthesise existing evidence on the observational and genetic associations between circulating proteins and CMD. Two investigators independently extracted study characteristics using a standard form and pooled data using random effects models.
Objectives In dyspneic patients with atrialfibrillation (AF) or obesity, the diagnostic performance of NT-proBNP for acute heart failure is reduced. In patients with AF, the AUC decreased for ERFE in each cohort (NZ: 0.71, n = 105, SG: 0.61, n = 44) but increased in patients with obesity (NZ: 0.79, n = 150, SG: 0.87, n = 164).
Torsade de pointes (TdP) was not a rare arrhythmia in Israel during the 1970s–1980s as many patients, mainly with atrialfibrillation (AF), were treated with QT-prolonging antiarrhythmic drugs. Our experience was published in 1981 in Circulation.1
Circulation: Cardiovascular Imaging, Ahead of Print. BACKGROUND:Patients with only moderate atrial secondary mitral regurgitation (asMR) frequently develop heart failure (HF). Mechanisms of HF with moderate asMR and the impact of mild asMR remain unclarified.
Her Apple Watch suddenly told her that she is in atrialfibrillation. Patients with healthy AV nodes who are not on AV nodal blockers and who are not hyperkalemic should have a rapid ventricular response if they have paroxysmal Atrialfibrillation. Exam was completely normal except for an irregular heart rate.
Getty Images milla1cf Fri, 12/08/2023 - 08:17 December 8, 2023 — The American College of Cardiology (ACC) and the American Heart Association (AHA), along with several other leading medical associations, have issued a new guideline for preventing and optimally managing atrialfibrillation (AFib). Additional Resources: After Nov.
Circulation, Volume 150, Issue Suppl_1 , Page A4141066-A4141066, November 12, 2024. Background:Clinical studies on atrialfibrillation (AF) recurrence after catheter ablation in patients diagnosed with patent foramen ovale (PFO) and paroxysmal AF (PAF) are scarce.
Circulation, Volume 150, Issue Suppl_1 , Page A4139226-A4139226, November 12, 2024. Background:Anticoagulation is the standard treatment for the majority of patients with atrialfibrillation (AF) to reduce the risk of stroke. Such patients are at high risk for bleeding and stroke.
Circulation: Arrhythmia and Electrophysiology, Ahead of Print. BACKGROUND:The strongest genetic risk factors for atrialfibrillation (AF) are DNA variants on chromosome 4q25 near the transcription factor genePITX2.
Circulation, Volume 150, Issue Suppl_1 , Page A4135095-A4135095, November 12, 2024. Background:While anticoagulation is crucial for atrialfibrillation (AF) patients to prevent ischemic events, those with thrombocytopenia have a potential increased risk of bleeding.
Circulation: Arrhythmia and Electrophysiology, Ahead of Print. BACKGROUND:Pulsed field ablation (PFA) is a promising treatment for atrialfibrillation. paroxysmal, and 58.5% deep sedation) were treated.
Circulation, Ahead of Print. BACKGROUND:The relationship between heart failure (HF) and atrialfibrillation (AF) is clear, with up to half of patients with HF progressing to AF. The pathophysiological basis of AF in the context of HF is presumed to result from atrial remodeling.
Circulation: Arrhythmia and Electrophysiology, Ahead of Print. BACKGROUND:It is difficult to identify patients with atrialfibrillation (AF) most likely to respond to ablation.
Circulation: Cardiovascular Imaging, Ahead of Print. BACKGROUND:Left atrial (LA) speckle tracking provides detailed information on atrial function. Its utility for predicting subclinical atrialfibrillation (SCAF) is unclear. Echocardiography included LA reservoir, conduit, and contraction strain.
Detection of one cause, paroxysmal atrialfibrillation (AF), is critical to ensuring optimal treatment with direct oral anticoagulant (DOAC). The primary outcome, presence of occult atrialfibrillation, was detected by ICM placement within 90 days and follow-up within 180 days from stroke.
Circulation, Volume 150, Issue Suppl_1 , Page A4139970-A4139970, November 12, 2024. Introduction:Anticoagulation (AC) is the mainstay of thromboprophylaxis for stroke prevention in atrialfibrillation (AF) and is recommended.
Circulation, Volume 150, Issue Suppl_1 , Page A4145826-A4145826, November 12, 2024. specificity.Conclusion:In this retrospective analysis, classification of the dynamic system model singular values identified patients at high risk for atrialfibrillation from sinus rhythm period. 17.64), yielding 72.9% sensitivity with 76.2%
Circulation, Volume 150, Issue Suppl_1 , Page A4137488-A4137488, November 12, 2024. Background:It is desirable to improve rhythm control management of atrialfibrillation (AF). Extracellular potassium ([K+]0) may affect AF generation and anti-AF efficacy of the sodium channel blockers.Methods:AF burden (i.e.,
Objective:Forward head posturing (FHP) has been associated with chronic anatomic vertebral artery disturbances possibly leading to posterior circulation ischemia. The data supporting FHP as a true risk factor of posterior circulation stroke has not been well established. The average C2 tilt of cases was 22.9 degrees compared to 17.7
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