Atrial Fibrillation, BMI and Strokes

Study Demonstrates Abelacimab Significantly Reduced Bleeding in Patients Regardless of Age, Bleeding Risk

DAIC

MARCH 31, 2025

In addition, abelacimab consistently reduced bleeding risk in patients 75 years of age and older regardless of renal function, body mass index (BMI), and the use of concomitant antiplatelet therapy. Patients with atrial fibrillation, particularly older patients, are frequently at a high risk of bleeding.

Atrial Fibrillation

Atrial Fibrillation BMI General Cardiology Thrombosis

Relationship between epicardial adipose tissue volume and atrial fibrillation in patients with rheumatoid arthritis

Frontiers in Cardiovascular Medicine

APRIL 8, 2025

IntroductionEpicardial adipose tissue (EAT) is involved in cardiac inflammatory responses and has been associated with both atrial fibrillation (AF) and rheumatoid arthritis (RA). The volume of EAT or EAT/BMI ratio was similar between the patients with RA and no AF and those without both RA and AF.

Atrial Fibrillation

Atrial Fibrillation BMI Strokes Stroke

Abstract 4142376: Impact of Atrial Fibrillation on Outcomes in Patients with Esophageal Cancer Receiving Neoadjuvant Chemoradiation

Circulation

NOVEMBER 11, 2024

Limited data indicate an elevated risk of atrial fibrillation (AF) after neoadjuvant chemoradiation in esophageal cancer however the role of AF as an independent predictor of outcomes post-esophagectomy remains under-studied. Outcomes over a 5-year period were mortality, ischemic stroke, and use of anticoagulation.

Atrial Fibrillation

Atrial Fibrillation Cancer Outcomes BMI

Webinars

Bridging Innovation & Patient Care: The Growing Role of AI

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Abstract DP42: A Stroke Case Management Program To Improve Hospital Readmission Rates After Index Stroke

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP42-ADP42, February 1, 2025. Introduction:The transitional period from hospital discharge to the community for stroke survivors is a vulnerable time as patients navigate healthcare systems with their new impairments. The control group included patients not enrolled in the program.

Hospital

Hospital Strokes Stroke Nursing

Abstract TP270: Development and Validation of a Nomogram Model for Predicting Early Neurological Deterioration in Acute Ischemic Stroke Patients Treated With Intravenous Thrombolysis

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP270-ATP270, February 1, 2024. Objective:A proportion of acute ischemic stroke (AIS) patients suffer from early neurological deterioration (END) within 24 hours following intravenous thrombolysis (IVT), which greatly increases the risk of poor prognosis of these patients.

Thrombolysis

Thrombolysis BMI Strokes Stroke

Abstract 4123899: Stroke Risk in Patients with an Isolated Interventricular Membranous Septal Aneurysm

Circulation

NOVEMBER 11, 2024

Aim:This study investigates the prevalence of isolated interventricular membranous septal (IVMS) aneurysms detected via echocardiography and assesses the associated stroke risk without other classical risk factors.Methods:We searched the echocardiography database at Mount Sinai Morningside from January 2017 to September 2023.

Aneurysm

Aneurysm Strokes Stroke Atrial Fibrillation

Abstract 131: Association Between Left Ventricular Injury Detected by Cardiac MRI and Incident Ischemic Stroke: The Multi-Ethnic Study of Atherosclerosis

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A131-A131, February 1, 2024. The primary outcome was incident ischemic stroke. There were a total of 18 ischemic stroke events among those with LVI (6%) and 65 among those without LVI (3%). Participants with LVI were significantly older, male, Black, had higher BMI, and lower HDL.

Atherosclerosis

Atherosclerosis Strokes Stroke Atrial Fibrillation

Abstract 52: Glucagon-like peptide-1 receptor agonists use and outcomes in Cardiac Amyloidosis patients: A Propensity Matched Analysis

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A52-A52, February 1, 2025. Primary outcome was risk of ischemic stroke while secondary outcomes were all-cause mortality (ACM), heart failure, acute myocardial infarction (AMI), major adverse cardiovascular events (MACE), atrial fibrillation (AF), and ventricular tachycardia (VT).Result:After

Outcomes

Outcomes Atrial Fibrillation Heart Failure Myocardial Infarction

Abstract 4148106: Hemophilia and Cardiovascular disease in the United States: Prevalence, Risk factors, and outcomes.

Circulation

NOVEMBER 11, 2024

The secondary outcomes comprise the odds of adverse events, including myocardial infarction, ischemic stroke, transient ischemic attack (TIA), occlusive atherosclerotic disease, percutaneous coronary intervention, and coronary artery bypass graft (CABG)., The hemophilia cohort was slightly older (63.2[16.8]

Risk Factors

Risk Factors Cardiovascular Disease Coronary Artery Bypass Graft Outcomes

Abstract WP231: The Incidence of Intracranial Hemorrhage in Patients Anticoagulated With Factor Xa Inhibitors (FXai): A Multi-Country Observational Study (AXIOM ICH)

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP231-AWP231, February 1, 2024. Individuals with FXai prescriptions for a therapeutic indication such as venous thromboembolism, atrial fibrillation (AF), and/or non-mechanical cardiac-valve replacement, were included. rivaroxaban and apixaban).Aim:To rivaroxaban and apixaban).Aim:To

Hemorrhage

Hemorrhage Atrial Fibrillation BMI Strokes

The association between the systemic immune-inflammation index and in-hospital mortality among acute ischemic stroke with atrial fibrillation patients undergoing intravenous thrombolysis

Frontiers in Cardiovascular Medicine

APRIL 6, 2025

Two sensitivity analyses confirmed the robustness of this association from multiple perspectives (P<0.05). ROC analysis demonstrated that the SII, the baseline model, and their combined model all showed strong predictive power for in-hospital mortality.

Thrombolysis

Thrombolysis Atrial Fibrillation Hospital Strokes

Efficacy and Safety of Non–Vitamin-K Antagonist Oral Anticoagulants Versus Warfarin Across the Spectrum of Body Mass Index and Body Weight: An Individual Patient Data Meta-Analysis of Four Randomized Clinical Trials of 58?464 Patients With Atrial Fibrillation

Circulation

JANUARY 24, 2024

The primary efficacy and safety outcomes were stroke or systemic embolic events (stroke/SEE) and major bleeding, respectively; secondary outcomes were ischemic stroke/SEE, intracranial hemorrhage, death, and the net clinical outcome (stroke/SEE, major bleeding, or death). Each outcome was examined across BMI and BW.

Atrial Fibrillation

Atrial Fibrillation BMI Strokes Stroke

Association of body mass index with outcomes in patients with newly diagnosed atrial fibrillation: GARFIELD-AF

Open Heart

AUGUST 5, 2022

Objective While greater body mass index (BMI) is associated with increased risk of developing atrial fibrillation (AF), the impact of BMI on outcomes in newly diagnosed AF is unclear. The study population comprised 40 482 participants: 703 underweight (BMI <18.5 kg/m 2 ), 13 095 normal (BMI=18.5–24.9

Atrial Fibrillation

Atrial Fibrillation BMI Outcomes Obesity

Abstract WP388: Plasma Eicosanoids Are Associated with Incident Stroke Over Decades in Participants in the Atherosclerosis Risk in Communities (ARIC) Study

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP388-AWP388, February 1, 2025. Incident stroke (ischemic and hemorrhagic) was ascertained until the end of 2021 with adjudication by an expert panel. Cox regression was used to estimate the hazard ratio (HR) for incident stroke per doubling of EIC levels, and p-values were FDR corrected.

Atherosclerosis

Atherosclerosis Strokes Stroke Atrial Fibrillation

Abstract TP186: Patients with Acute Ischemic Stroke in the United States Exhibit more Dependency 90 Days after Stroke than those in a Matched Norwegian Cohort

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP186-ATP186, February 1, 2025. Introduction:Acute ischemic stroke (AIS) imposes a disparate burden across global populations. Understanding drivers of such heterogeneity is particularly important in the context of international stroke clinical trials design.

Strokes

Strokes Stroke Thrombolysis Atrial Fibrillation

Decoding Longevity. How To Not Die. Young

Dr. Paddy Barrett

JANUARY 16, 2024

Share Cardiovascular Disease Those in the ‘Ideal’ category were 55% less likely to develop diseases of the circulatory system, including: Heart Disease Stroke Heart Failure Atrial Fibrillation For each 10-point increment in lifestyle score, there was a proportionate 20% reduction in these conditions combined.

Cancer

Cancer Dementia Diabetes Cardiovascular Disease

Abstract 4141539: Impact of Left Ventricular End-Diastolic Diameter on the Prognosis in Patients with Atrial Fibrillation and Acute Coronary Syndrome or Undergoing PCI

Circulation

NOVEMBER 11, 2024

The primary endpoint was MACEs, which represented a composite event of all-cause death, stroke, systemic embolism, and massive hemorrhage.Results:The 2,182 patients were divided into two groups: LVEDD＞60mm group (n=370) and LVEDD ≤60 mm group (n=1812).

Atrial Fibrillation

Atrial Fibrillation Coronary Artery Bypass Graft Coronary Artery Disease Myocardial Infarction

Cardiovascular Update

Study Demonstrates Abelacimab Significantly Reduced Bleeding in Patients Regardless of Age, Bleeding Risk

Relationship between epicardial adipose tissue volume and atrial fibrillation in patients with rheumatoid arthritis

Abstract 4142376: Impact of Atrial Fibrillation on Outcomes in Patients with Esophageal Cancer Receiving Neoadjuvant Chemoradiation

Webinars

Abstract DP42: A Stroke Case Management Program To Improve Hospital Readmission Rates After Index Stroke

Abstract TP270: Development and Validation of a Nomogram Model for Predicting Early Neurological Deterioration in Acute Ischemic Stroke Patients Treated With Intravenous Thrombolysis

Abstract 4123899: Stroke Risk in Patients with an Isolated Interventricular Membranous Septal Aneurysm

Abstract 131: Association Between Left Ventricular Injury Detected by Cardiac MRI and Incident Ischemic Stroke: The Multi-Ethnic Study of Atherosclerosis

Abstract 52: Glucagon-like peptide-1 receptor agonists use and outcomes in Cardiac Amyloidosis patients: A Propensity Matched Analysis

Abstract 4148106: Hemophilia and Cardiovascular disease in the United States: Prevalence, Risk factors, and outcomes.

Abstract WP231: The Incidence of Intracranial Hemorrhage in Patients Anticoagulated With Factor Xa Inhibitors (FXai): A Multi-Country Observational Study (AXIOM ICH)

The association between the systemic immune-inflammation index and in-hospital mortality among acute ischemic stroke with atrial fibrillation patients undergoing intravenous thrombolysis

Efficacy and Safety of Non–Vitamin-K Antagonist Oral Anticoagulants Versus Warfarin Across the Spectrum of Body Mass Index and Body Weight: An Individual Patient Data Meta-Analysis of Four Randomized Clinical Trials of 58?464 Patients With Atrial Fibrillation

Association of body mass index with outcomes in patients with newly diagnosed atrial fibrillation: GARFIELD-AF

Abstract WP388: Plasma Eicosanoids Are Associated with Incident Stroke Over Decades in Participants in the Atherosclerosis Risk in Communities (ARIC) Study

Abstract TP186: Patients with Acute Ischemic Stroke in the United States Exhibit more Dependency 90 Days after Stroke than those in a Matched Norwegian Cohort

Decoding Longevity. How To Not Die. Young

Abstract 4141539: Impact of Left Ventricular End-Diastolic Diameter on the Prognosis in Patients with Atrial Fibrillation and Acute Coronary Syndrome or Undergoing PCI

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