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University Hospitals Researcher Develops New Score System to Better Screen and Treat HFpEF Heart Failure Patients

DAIC

It incorporates age, body mass index (BMI), and atrial fibrillation to aid in the diagnosis of HFpEF. The newly developed HFpEF-ABA score model estimates the probability of HFpEF in individual patients based on three simple clinical variables: age, BMI, and atrial fibrillation.

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Evidence-Based Application of Natriuretic Peptides in the Evaluation of Chronic Heart Failure With Preserved Ejection Fraction in the Ambulatory Outpatient Setting

Circulation

Optimal NT-proBNP cut points for HFpEF rule out (optimizing sensitivity) and rule in (optimizing specificity) were derived and tested, stratified by obesity and atrial fibrillation. Current consensus age- and BMI-stratified rule-in thresholds demonstrated only 65% specificity (95% CI, 57%72%).

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Body mass index as a determinant of scar formation post‐AF ablation: Insights from DECAAF II

Journal of Cardiovascular Electrophysiology

Obesity is associated with reduced catheter ablation-induced scar formation on late-gadolinium enhancement MRI. Abstract Introduction Obesity is implicated in adverse atrial remodeling and worse outcomes in patients with atrial fibrillation. Ablation parameters and lesion delivery were not dependent on BMI.

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Abstract 4123899: Stroke Risk in Patients with an Isolated Interventricular Membranous Septal Aneurysm

Circulation

The mean BMI was 27.9 kg/m2, with 4 classified as obese. Only one patient had paroxysmal atrial fibrillation, with a CHA2DS2-VASc score of 0. Echocardiography revealed structurally normal hearts with a mean left ventricular ejection fraction of 61% and a mean left atrial volume index of 24.8

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Association of body mass index with outcomes in patients with newly diagnosed atrial fibrillation: GARFIELD-AF

Open Heart

Objective While greater body mass index (BMI) is associated with increased risk of developing atrial fibrillation (AF), the impact of BMI on outcomes in newly diagnosed AF is unclear. The study population comprised 40 482 participants: 703 underweight (BMI <18.5 kg/m 2 ), 13 095 normal (BMI=18.5–24.9

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Semaglutide Leads to Greater Weight Loss in Women than Men with HF, Improves HF Symptoms in Both Sexes

DAIC

Getty Images milla1cf Wed, 06/26/2024 - 18:59 June 26, 2024 — Semaglutide , a medication initially developed for type 2 diabetes and obesity, significantly improves symptoms in men and women with a common type of heart failure that has had few therapeutic options. The study analyzed the effects of semaglutide 2.4