Journal of Cardiovascular Electrophysiology

DECEMBER 23, 2024

ABSTRACT Introduction Catheter ablation of persistent atrial fibrillation yields sub-optimal success rates partly due to the considerable heterogeneity within the patient population. Methods We studied all patients who underwent catheter ablation of persistent atrial fibrillation in the DECAAF II trial.

Atrial Fibrillation 40

Atrial Fibrillation BMI Ablation Arrhythmia 40

DAIC

JULY 31, 2024

It incorporates age, body mass index (BMI), and atrial fibrillation to aid in the diagnosis of HFpEF. The newly developed HFpEF-ABA score model estimates the probability of HFpEF in individual patients based on three simple clinical variables: age, BMI, and atrial fibrillation.

Heart Failure 111

Heart Failure Preserved Ejection Fraction Research Hospital 111

Circulation

JANUARY 22, 2025

Optimal NT-proBNP cut points for HFpEF rule out (optimizing sensitivity) and rule in (optimizing specificity) were derived and tested, stratified by obesity and atrial fibrillation. Current consensus age- and BMI-stratified rule-in thresholds demonstrated only 65% specificity (95% CI, 57%72%).

Preserved Ejection Fraction 55

Preserved Ejection Fraction Outpatient Heart Failure BMI 55

Circulation

NOVEMBER 11, 2024

Limited data indicate an elevated risk of atrial fibrillation (AF) after neoadjuvant chemoradiation in esophageal cancer however the role of AF as an independent predictor of outcomes post-esophagectomy remains under-studied. Circulation, Volume 150, Issue Suppl_1 , Page A4142376-A4142376, November 12, 2024.

Atrial Fibrillation 40

Atrial Fibrillation Cancer Outcomes BMI 40

HeartRhythm

APRIL 30, 2024

Previous studies have shown that a higher BMI is associated with AF recurrence after AF ablation using conventional thermal ablative modalities, such as radiofrequency (RF) or cryotherapy (Cryo).

Ablation 40

Ablation Atrial Fibrillation BMI Outcomes 40

European Journal of Heart Failure

NOVEMBER 26, 2024

BMI, body mass index; eGFR, estimated glomerular filtration rate; NYHA, New York Heart Association. 1.38), a diagnosis of atrial fibrillation (HR 1.24, 95% CI 1.10–1.39), Discontinuation and reinitiation of mineralocorticoid receptor antagonists (MRA) in patients with heart failure and reduced ejection fraction (HFrEF).

Heart Failure 71

Heart Failure Kidney Disease Atrial Fibrillation BMI 71

Journal of Cardiovascular Electrophysiology

DECEMBER 17, 2024

Abstract Introduction Obesity is implicated in adverse atrial remodeling and worse outcomes in patients with atrial fibrillation. The objective of this study is to assess the effect of body mass index (BMI) on ablation-induced scar formation on late gadolinium enhancement cardiac magnetic resonance imaging (LGE-CMR).

Ablation 40

Ablation BMI Obesity Atrial Fibrillation 40

Stroke Journal

FEBRUARY 1, 2024

These results were successfully validated internally and externally.Conclusions:NLR, MPV, BMI and AF were independent risk factors and predictors of ENDi. The area under the curve of the prediction model constructed from the above four factors was 0.981 (95% CI 0.961-1.000) and the calibration curve was close to the ideal diagonal line.

Thrombolysis 40

Thrombolysis BMI Stroke Strokes 40

Journal of Cardiovascular Electrophysiology

JANUARY 28, 2024

Abstract Introduction During atrial fibrillation ablation (AFA), achievement of first pass isolation (FPI) reflects effective lesion formation and predicts long-term freedom from arrhythmia recurrence. Multivariate analysis showed that BMI > 30 (OR 0.78 [0.64–0.96]) 0.96]) and LA volume (OR per mL increase = 1.00 [0.99–1.00])

Ablation 40

Ablation Pulmonary BMI Atrial Fibrillation 40

Stroke Journal

JANUARY 30, 2025

Propensity score-matched analysis (PSM) (1:1) was performed with matching for age, gender, race, BMI, hypertension, diabetes mellitus, chronic kidney disease, hemoglobin level, low-density lipid (LDL) level, left ventricular ejection fraction, and various drugs including ACEi, ARBi, ARNI, beta-blockers, and diuretics.

Outcomes 40

Outcomes Atrial Fibrillation Heart Failure Tachycardia 40

Circulation

NOVEMBER 11, 2024

17.4]) and was also more likely to have diabetes mellitus, hyperlipidemia, chronic lung disease, chronic kidney disease, chronic liver disease, BMI ≥ 25, anemia, metastatic cancer, and atrial fibrillation. The hemophilia cohort was slightly older (63.2[16.8]

Risk Factors 40

Risk Factors Cardiovascular Disease Coronary Artery Bypass Graft Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Individuals with FXai prescriptions for a therapeutic indication such as venous thromboembolism, atrial fibrillation (AF), and/or non-mechanical cardiac-valve replacement, were included. There is a paucity of accurate national incidence rate data on ICH, fatal ICH and ICH sub-types in patients on FXai anticoagulants (e.g.

Hemorrhage 40

Hemorrhage Atrial Fibrillation BMI Stroke 40

Stroke Journal

JANUARY 30, 2025

Outcomes were 1 year hospital readmission rates by all-cause and due to repeat stroke.Results:Patients in the intervention group and control group were similar in age, BMI, race, smoking status, as well as rates of hypertension, diabetes, hyperlipidemia, atrial fibrillation, and history of prior stroke, with the exception of discharge rate to skilled (..)

Hospital 40

Hospital Stroke Strokes Nursing 40

Stroke Journal

FEBRUARY 1, 2024

Participants with LVI were significantly older, male, Black, had higher BMI, and lower HDL. Participants with LVI were more likely to have diabetes, tobacco use, and atrial fibrillation (24% versus 14%, p<0.001). There were a total of 18 ischemic stroke events among those with LVI (6%) and 65 among those without LVI (3%).

Atherosclerosis 40

Atherosclerosis Stroke Strokes Atrial Fibrillation 40

Circulation

NOVEMBER 11, 2024

The mean BMI was 27.9 Only one patient had paroxysmal atrial fibrillation, with a CHA2DS2-VASc score of 0. Echocardiography revealed structurally normal hearts with a mean left ventricular ejection fraction of 61% and a mean left atrial volume index of 24.8 Of these, 9 (64%) were female with a mean age of 59.6,

Aneurysm 40

Aneurysm Stroke Strokes Atrial Fibrillation 40

Frontiers in Cardiovascular Medicine

APRIL 6, 2025

Two sensitivity analyses confirmed the robustness of this association from multiple perspectives (P<0.05).

Thrombolysis 52

Thrombolysis Atrial Fibrillation Hospital Stroke 52

Circulation

JANUARY 24, 2024

Each outcome was examined across BMI and BW. Because few patients had a BMI &lt;18.5 kg/m2(n=598), the primary analyses were restricted to those with a BMI ≥18.5 RESULTS:Among 58 464 patients, the median BMI was 28.3 Because few patients had a BMI &lt;18.5 interquartile range, 25.2–32.2)

Atrial Fibrillation 80

Atrial Fibrillation BMI Stroke Strokes 80

Open Heart

AUGUST 5, 2022

Objective While greater body mass index (BMI) is associated with increased risk of developing atrial fibrillation (AF), the impact of BMI on outcomes in newly diagnosed AF is unclear. The study population comprised 40 482 participants: 703 underweight (BMI <18.5 kg/m 2 ), 13 095 normal (BMI=18.5–24.9

Atrial Fibrillation 52

Atrial Fibrillation BMI Outcomes Obesity 52

European Journal of Heart Failure

APRIL 13, 2025

BMI, body mass index; LVEF, left ventricular ejection fraction; NT-proBNP, N-terminal pro-B-type natriuretic peptide. The beneficial effects of finerenone in patients with heart failure (HF) and mildly reduced or preserved ejection fraction were consistent, regardless of a history of chronic obstructive pulmonary disease (COPD) status.

Preserved Ejection Fraction 40

Preserved Ejection Fraction Heart Failure Pulmonary Peripheral Arterial Disease 40

DAIC

JUNE 26, 2024

Semaglutide-mediated improvements in HF-related symptoms and physical limitations were consistent in both male and female participants across key subgroups including age and BMI. It also lowered their systolic blood pressure and waist circumference.

Preserved Ejection Fraction 105

Preserved Ejection Fraction Obesity BMI Heart Failure 105

Stroke Journal

JANUARY 30, 2025

Results:Among the 9,444 participants included, the mean age was 57 (5.7 SD), and 43.2% were men.

Atherosclerosis 40

Atherosclerosis Stroke Strokes Atrial Fibrillation 40

European Journal of Heart Failure

DECEMBER 10, 2024

Then identified clusters are predicted and tested in the learning set to evaluate their association with outcomes. Finally, the reproducibility of the results of cluster analysis is tested in an external cohort (validation set). The derived algorithm was applied in the COMMANDER-HF trial ( n =5022) for external validation.

Heart Failure 40

Heart Failure Peripheral Arterial Disease Blood Pressure Atrial Fibrillation 40

Stroke Journal

JANUARY 30, 2025

Cohorts were matched on age, sex, diabetes, atrial fibrillation, and hypertension. The US cohort had greater ethno-racial heterogenity, higher BMI, and higher NIHSS on admission. The NOR cohort had a significantly higher proportion of previous/current smokers and a higher prevalence of hypercholesterolemia.

Stroke 40

Stroke Strokes Thrombolysis Atrial Fibrillation 40

Dr. Paddy Barrett

JANUARY 16, 2024

Share Cardiovascular Disease Those in the ‘Ideal’ category were 55% less likely to develop diseases of the circulatory system, including: Heart Disease Stroke Heart Failure Atrial Fibrillation For each 10-point increment in lifestyle score, there was a proportionate 20% reduction in these conditions combined.

Cancer 97

Cancer Dementia Diabetes Cardiovascular Disease 97

Circulation

NOVEMBER 11, 2024

The primary endpoint was MACEs, which represented a composite event of all-cause death, stroke, systemic embolism, and massive hemorrhage.Results:The 2,182 patients were divided into two groups: LVEDD＞60mm group (n=370) and LVEDD ≤60 mm group (n=1812).

Atrial Fibrillation 40

Atrial Fibrillation Coronary Artery Bypass Graft Coronary Artery Disease Myocardial Infarction 40

European Journal of Heart Failure

MARCH 30, 2025

The lower part of the figure shows the risk of mortality according to continuous body mass index (BMI) ( left panel ) and waist-to-height ratio (WHtR) ( right panel ). Compared to a BMI 18.524.9kg/m 2 , a BMI <18.5kg/m 2 ( n =24) was associated with a numerically, but not a significantly, higher risk of all-cause and cardiovascular death.

Heart Failure 40

Heart Failure BMI Obesity Blood Pressure 40

Frontiers in Cardiovascular Medicine

JANUARY 13, 2025

Age, BMI, hypertension, CHA2DS-VASC score, neutrophil to lymphocyte ratio (NLR), LAA volume, LA volume, the myocardial thickness at the junction of LAA and LA, the area, circumference, short diameter, and long diameter of the LAA opening, were significantly different between the AF group and the control group (P<0.05).

Atrial Fibrillation 52

Atrial Fibrillation BMI Hypertension Hospital 52

Frontiers in Cardiovascular Medicine

JANUARY 1, 2025

Further regression analysis indicated that body mass index (BMI) might be related to changes in LAD. However, the optimal range for ventricular rate control remains unclear. Specifically, the severity of cardiac remodeling, including LVEDD, LAD, LVEF, and mitral regurgitation, showed the following trend: Group II

Atrial Fibrillation 52

Atrial Fibrillation Bicuspid/Mitral Coronary Artery Disease BMI 52

Journal of Cardiovascular Electrophysiology

JANUARY 5, 2025

ABSTRACT Introduction Epicardial adipose tissue (EAT) is often associated with atrial fibrosis, and both can provide the substrate for atrial fibrillation (AF). However, most AF patients have no evidence of left atrial (LA) fibrosis based on bipolar voltage mapping. cm, p <0.001) and higher right atrial EAT (7.3

Atrial Fibrillation 40

Atrial Fibrillation BMI Ablation Arrhythmia 40