Frontiers in Cardiovascular Medicine

JANUARY 21, 2025

Atrial fibrillation is the most prevalent arrhythmia with a lifetime risk of nearly 30%. It can be associated with reduced quality of life and complications such as heart failure and stroke. Pulmonary vein isolation (PVI) is the most effective treatment for rhythm control.

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Atrial Fibrillation Quality of Life Ablation Electrophysiology 52

Science Daily - Heart Disease

DECEMBER 16, 2024

atrial fibrillation (AF), a heart condition that causes an irregular heartbeat in the upper chambers of the heart, affects up to one in three people in their lifetime. In the U.S., In a new review article scientists summarize the current evidence regarding the epidemiology, pathophysiology, diagnosis and management of AF.

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Atrial Fibrillation Myocardial Infarction Kidney Disease Dementia 114

Heart BMJ

JANUARY 29, 2025

The observational cohort study by Trancado et al examines the efficacy and toxicity of flecainide for rhythm control therapy of atrial fibrillation (AF) depending on a common gene polymorphism in the SCN5A gene, histidine-558-to-arginine (H558R).

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Atrial Fibrillation Research 52

Frontiers in Cardiovascular Medicine

FEBRUARY 10, 2025

BackgroundThis study examines the anatomical characteristics of the mitral isthmus (MI) and its spatial relationship with the esophagus in patients undergoing atrial fibrillation ablation, using cardiovascular computed tomographic angiography (CTA).

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Atrial Fibrillation Bicuspid/Mitral Ablation Research 52

Frontiers in Cardiovascular Medicine

MARCH 20, 2025

ObjectiveThis study aimed to investigate the effects of Enhanced External Counterpulsation (EECP) on anxiety and depression in patients with Paroxysmal Atrial Fibrillation (PAF).MethodsA MethodsA cohort of 100 patients diagnosed with PAF at the Fuzhou First Hospital between January 2023 and June 2024 were enrolled in this study.

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Atrial Fibrillation Blood Pressure Pharmacology Ultrasound 59

Medical Xpress - Cardiology

DECEMBER 19, 2024

Drinking multiple cups of coffee a day may help prevent cognitive decline in people with atrial fibrillation (AFib or AF), according to new research published in the Journal of the American Heart Association.

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Atrial Fibrillation Research AFIB 119

Frontiers in Cardiovascular Medicine

APRIL 3, 2025

BackgroundNon-valvular atrial fibrillation (NVAF) significantly increases ischemic stroke and systemic embolism (SE) risks. Despite the proven efficacy of oral anticoagulants (OAC) in reducing these risks, their underutilization highlights a gap in clinical practice.

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Atrial Fibrillation Hospital Dementia Embolism 52

Science Daily - Heart Disease

APRIL 11, 2025

Researchers have developed an AI tool that creates synthetic yet medically accurate models of fibrotic heart tissue (heart scarring), aiding treatment planning for atrial fibrillation (AF) patients. The study could lead to more personalized care for patients affected by this common heart rhythm disorder.

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Atrial Fibrillation Heart Rhythm Research 98

JAMA Cardiology

MARCH 28, 2025

This secondary analysis of the Finerenone Trial to Investigate Efficacy and Safety Superior to Placebo in Patients With Heart Failure (FINEARTS-HF) randomized clinical trial examines the efficacy and safety of finerenone in patients with heart failure with mildly reduced or preserved ejection fraction according to the presence and type of atrial fibrillation. (..)

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Atrial Fibrillation Heart Failure Preserved Ejection Fraction 94

Frontiers in Cardiovascular Medicine

NOVEMBER 12, 2024

This was also consistent in patients weighing less than 50 kg.ConclusionsIn the real world, in lower-weight patients with nonvalvular atrial fibrillation, a reduced dose of rivaroxaban did not reduce the risk of bleeding, and this was consistent in patients weighing less than 50 kg.

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Atrial Fibrillation Outpatient Hospital 59

Open Heart

APRIL 5, 2025

Objective Pulsed-field ablation (PFA) is a new technology of catheter ablation for atrial fibrillation (AF). This research is to investigate the feasibility of a new strategy (transoesophageal echocardiography-guided pulsed field ablation, TEEP) to guide PFA for AF with no contrast and zero fluoroscopy.

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Atrial Fibrillation Ablation Pulmonary Technology 52

Nature Reviews - Cardiology

FEBRUARY 27, 2024

Nature Reviews Cardiology, Published online: 28 February 2024; doi:10.1038/s41569-024-01004-2 Atrial fibrillation is the most common sustained arrhythmia and imposes a substantial burden on patients and health-care providers.

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Atrial Fibrillation Arrhythmia Outcomes 107

Medical Xpress - Cardiology

APRIL 11, 2025

Researchers from Queen Mary University of London have developed an AI tool that creates synthetic yet medically accurate models of fibrotic heart tissue (heart scarring), aiding treatment planning for atrial fibrillation (AF) patients.

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Atrial Fibrillation Heart Rhythm Research 97

Journal of the American Heart Association

APRIL 17, 2025

BackgroundNonvitamin K oral anticoagulants prevent stroke and systemic embolism in patients with nonvalvular atrial fibrillation. Our analysis included 22 568 patients with nonvalvular atrial fibrillation (aged 75.7 years; 51.2%

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Atrial Fibrillation Hemorrhage Embolism Hospital 40

Frontiers in Cardiovascular Medicine

APRIL 23, 2025

ObjectiveThe aim of this study was to investigate the impact of preprocedural anticoagulation on the incidence of silent cerebral embolisms (SCEs) assessed by magnetic resonance imaging (MRI) after catheter ablation of atrial fibrillation (AF) in patients with low thromboembolic risk.Methods and resultsA total of 141 patients with AF who were identified (..)

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Atrial Fibrillation Embolism Ablation Pulmonary 52

Science Daily - Heart Disease

JANUARY 22, 2025

Researchers evaluated a drug that represents a new class of anticoagulants known as Factor XI inhibitors for treating patients with atrial fibrillation as part of the AZALEA-TIMI 71 Study.

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Atrial Fibrillation Research 116

Frontiers in Cardiovascular Medicine

FEBRUARY 24, 2025

Radiofrequency ablation (RFA) is an important therapeutic modality for atrial fibrillation (AF), widely utilized in clinical practice due to its safety and significant efficacy. Head CT scans showed hypoattenuating areas indicative of cerebral infarction, chest CT suggested possible air accumulation in the left atrial region.

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Atrial Fibrillation Ablation Cardiogenic Shock Myocardial Infarction 52

The British Journal of Cardiology

MARCH 4, 2025

This review provides information about the current evidence-base for screening for atrial fibrillation (AF). Finally, novel methods to refine the population to whom AF screening should be offered, which may improve clinical and cost-effectiveness, are considered.

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Atrial Fibrillation Outcomes Stroke Strokes 40

Medical Xpress - Cardiology

JANUARY 23, 2025

Patients with atrial fibrillation are typically prescribed an anticoagulant, or blood thinner, to reduce the risk of stroke, but many may discontinue them or never receive a prescription due to concerns of increased risk of bleeding complications.

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Atrial Fibrillation Stroke Strokes 115

Medical Xpress - Cardiology

MARCH 6, 2025

Two studies led by researchers at the Broad Institute of MIT and Harvard and Mass General Brigham have greatly expanded the number of known genetic variants that boost the risk for atrial fibrillation (AF), a common heart condition marked by an irregular heartbeat that can lead to stroke and heart failure.

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Atrial Fibrillation Heart Failure Research Stroke 103

Frontiers in Cardiovascular Medicine

JANUARY 23, 2025

The increased use of radiofrequency ablation (RFA) for atrial fibrillation (AF) has led to a rise in cases of pulmonary vein stenosis or occlusion (PVS/O) as a complication. While this occurrence was once rare, the growing number of patients undergoing this procedure has made it more prevalent.

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Atrial Fibrillation Stenosis Pulmonary Ablation 52

Frontiers in Cardiovascular Medicine

FEBRUARY 27, 2025

BackgroundInstant atrial fibrillation termination (AFT) during radiofrequency ablation has been suggested as a predictor of prognosis in persistent atrial fibrillation (AF). However, its role in cryoballoon ablation remains unclear.

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Atrial Fibrillation Ablation Arrhythmia Outcomes 52

HCPLive

NOVEMBER 17, 2024

Oussama Wazni, MD, discusses the results of the OPTION trial examining LAAC in atrial fibrillation as well as its reception as AHA 2024.

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Atrial Fibrillation 106

JAMA Cardiology

JUNE 25, 2024

This genetic association study evaluates the association of genetic variants with atrial fibrillation, cardiomyopathy, and heart failure.

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Atrial Fibrillation Heart Failure Cardiomyopathy 95

Heart BMJ

MARCH 26, 2025

Background Atrial fibrillation (AF) is a major and increasing burden on health services. This study aimed to evaluate the cost-effectiveness of digoxin versus beta-blockers for heart rate control in patients with permanent AF and symptoms of heart failure.

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Atrial Fibrillation Quality of Life Heart Failure 40

Heart BMJ

MARCH 26, 2025

Beta-blockers probably prevent atrial fibrillation with a large magnitude of effect (RR 0.4, to 0.59) may reduce the risk of postoperative atrial fibrillation. to 0.59) may reduce the risk of postoperative atrial fibrillation. Results We included 39 trials that enrolled a total of 6419 participants.

Open-Heart Surgery 85

Open-Heart Surgery Pharmacology Atrial Fibrillation Pericarditis 85

HeartRhythm

JANUARY 23, 2025

Pulsed-field ablation (PFA) offers notable advantages in atrial fibrillation (AF) ablation by selectively targeting cardiomyocytes via an irreversible electroporation mechanism, thereby minimizing damage to surrounding tissues.

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Atrial Fibrillation Ablation Risk Factors 40

Medical Xpress - Cardiology

OCTOBER 10, 2024

Three common cardiovascular diseases in adults—heart failure, atrial fibrillation and coronary heart disease—are linked to cognitive impairment and increased risk of dementia, according to "Cardiac Contributions to Brain Health," a new scientific statement from the American Heart Association published today in the journal, Stroke.

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Atrial Fibrillation Heart Failure Heart Disease Dementia 100

Medical Xpress - Cardiology

APRIL 15, 2024

An analysis of the biomolecule substudy of the EAST–AFNET 4 trial has revealed that biomolecule concentrations in the blood of patients with atrial fibrillation can be used to identify patients at high and low cardiovascular risk. The findings were published in Cardiovascular Research.

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Atrial Fibrillation Circulation Research 111

Frontiers in Cardiovascular Medicine

NOVEMBER 7, 2024

Previous studies evaluated its value in predicting atrial fibrillation (AF) occurrence. IntroductionCorrected QT interval (QTc) is a ventricular repolarization marker on electrocardiography.

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Atrial Fibrillation Ablation 52

Heart BMJ

JANUARY 29, 2025

Background The SCN5A gene polymorphism histidine-558-to-arginine (H558R) has been associated with atrial fibrillation (AF) and may affect the therapeutic effects of flecainide.

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Atrial Fibrillation Outcomes 52

Open Heart

JANUARY 21, 2025

Background Atrial fibrillation (AF) and acute myocardial infarction (AMI) share risk factors and are bidirectionally associated. Several studies found higher risks of outcomes in individuals with both conditions. Whether the risks of outcomes differ according to temporal order of AF and AMI is unclear.

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Myocardial Infarction Atrial Fibrillation Diet Cancer 52

DAIC

APRIL 18, 2024

Based on continuous monitoring of early recurrence of atrial tachyarrhythmia immediately after patients have undergone atrial fibrillation ablation, Musat et al. recommend shortening the blanking period from three months to one. also emphasize the importance of continuous monitoring.

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Atrial Fibrillation Ablation Heart Rhythm Article 111

Cardiovascular Diabetology

APRIL 4, 2024

This study investigates the relationship between triglyceride-glucose (TyG) index trajectories and the results of ablation in patients with stage 3D atrial fibrillation (AF).

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Atrial Fibrillation Ablation Outcomes Research 105

Frontiers in Cardiovascular Medicine

APRIL 21, 2025

BackgroundAtrial fibrillation (AF) is a common arrhythmia associated with an increased risk of stroke, heart failure, and mortality. Immune infiltration plays a crucial role in AF pathogenesis, yet its mechanisms remain unclear.

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Atrial Fibrillation Biomarkers Heart Failure Arrhythmia 52

Journal of Clinical Investigation - Cardiology

SEPTEMBER 17, 2024

Obesity is linked to an increased risk of atrial fibrillation (AF) via increased oxidative stress. Here, we studied NOX2-mediated ROS production in obesity-mediated AF using Nox2-knockout mice and mature human induced pluripotent stem cell–derived atrial cardiomyocytes (hiPSC-aCMs).

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Obesity Atrial Fibrillation Diet 97

The New England Journal of Medicine

APRIL 2, 2025

After atrial fibrillation ablation, left atrial appendage closure was associated with a lower risk of bleeding than oral anticoagulation and was noninferior to oral anticoagulation with respect to clinical outcomes at 36 months.

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Atrial Fibrillation Ablation Outcomes 74