article thumbnail

Winning the Battle Against Atherosclerosis: Practical, Proactive Solutions

Cardiometabolic Health Congress

Atherosclerosis (ASVD) remains a leading driver of cardiovascular disease (CVD), a global health challenge that claims millions of lives each year. The Way Forward: Turning Research into Real-World Change The fight against atherosclerosis requires proactive, evidence-based action. But what if prevention could rewrite the narrative?

article thumbnail

Strong Dose-Response Relationship Between Smoking, Subclinical CVD Markers

American College of Cardiology

According to a new study published in JACC, there is a strong dose-response relationship between cigarette smoking and three different domains of subclinical cardiovascular markers: inflammation, thrombosis and subclinical atherosclerosis.

article thumbnail

Noncigarette Tobacco Product Use Increases Subclinical Markers Related to CV Harm

American College of Cardiology

The use of noncigarette tobacco products is associated with considerable cardiovascular risk, as demonstrated by relevant inflammation, thrombosis and atherosclerosis markers, according to a cross-sectional study published Jan.

article thumbnail

Potential biomarkers and immune characteristics for polycythemia vera-related atherosclerosis using bulk RNA and single-cell RNA datasets: a combined comprehensive bioinformatics and machine learning analysis

Frontiers in Cardiovascular Medicine

Thrombosis is the main risk event of this disease. Atherosclerosis (AS) can markedly increase the risk of arterial thrombosis in patients with PV. BackgroundPolycythemia vera (PV) is a myeloproliferative disease characterized by significantly higher hemoglobin levels and positivity for JAK2 mutation.

article thumbnail

Dynamic OMI ECG. Negative trops and negative angiogram does not rule out coronary ischemia or ACS.

Dr. Smith's ECG Blog

Thus, angiography may be fairly accurate in determining lumen size, but it will not detect the “volume” of atherosclerosis present. It is not small but rather large plaques, which may not be producing significant stenosis, that undergo rupture with acute occlusive thrombosis, resulting in myocardial infarction and other ischemic events.

Ischemia 121
article thumbnail

Your Top Five Questions About CMHC On-Demand, Answered

Cardiometabolic Health Congress

Dyslipidemia, Atherosclerosis & Thrombosis: Explore non-statin therapies, strategies for managing hypertriglyceridemia, and new guidance on lipoprotein(a) management. Diabetes Management: Gain insights into precision medicine, advanced insulin therapies, and continuous glucose monitoring (CGM) for cardiovascular risk assessment.

CME 52
article thumbnail

Abstract WP260: The Role of Fibrinogen in the Pathogenesis of Intracranial Atherosclerosis-Related Large Vessel Occlusion Strokes

Stroke Journal

Background:The mechanisms by which intracranial atherosclerosis (ICAS) contributes to large-vessel occlusion strokes (LVOS) remains unclear. Stroke, Volume 56, Issue Suppl_1 , Page AWP260-AWP260, February 1, 2025. Among patients with lower fibrinogen levels (< 3.2g/L),