DAIC

FEBRUARY 1, 2024

February 1, 2024 — As cardiologists, heart disease patients and the organizations that serve them across the country embark on American Heart Month, DAIC has compiled a snapshot of significant cardiovascular disease (CVD) and stroke statistics, along with a review of the atherosclerosis drug market. per 1,000* - 122.4

Cardiovascular Disease 104

Cardiovascular Disease Atherosclerosis Stroke Strokes 104

Medical Xpress - Cardiology

NOVEMBER 20, 2024

In a new study published in the European Heart Journal, researchers at Karolinska Institutet show that genetic traits influence the cellular composition of atherosclerotic plaques, which over time will affect the risk of such lesions for causing a stroke or heart attack.

Heart Attack 96

Heart Attack Heart attacks Plaque Stroke 96

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP56-AWP56, February 1, 2025. Introduction:Prior studies have shown the association between oral infection, white matter hyperintensity (WMH), a marker of cerebral small vessel disease (CSVD), and asymptomatic intracranial atherosclerosis (ICAS). CSVD was assessed using the log of WMH volume.

Atherosclerosis 75

Atherosclerosis Stenosis Risk Factors Education 75

Science Daily - Heart Disease

NOVEMBER 13, 2024

Researchers have identified a new target to treat atherosclerosis, a condition where plaque clogs arteries and causes major cardiac issues, including stroke and heart attack.

Cardiovascular Disease 110

Cardiovascular Disease Heart Attack Heart attacks Plaque 110

Science Daily - Heart Disease

APRIL 30, 2024

Researchers have discovered that the smooth muscle cells that line the arteries of people with atherosclerosis can change into new cell types and develop traits similar to cancer that worsen the disease.

Atherosclerosis 58

Atherosclerosis Cancer Peripheral Arterial Disease Coronary Artery Disease 58

Science Daily - Stroke

JANUARY 24, 2024

A team has demonstrated new mechanisms that are involved in the development of inflammatory cardiovascular diseases.

Atherosclerosis 113

Atherosclerosis Cardiovascular Disease 113

Science Daily - Heart Disease

FEBRUARY 19, 2024

Higher circulating levels of 4PY were strongly associated with development of heart attack, stroke and other adverse cardiac events in large-scale clinical studies. The researchers also showed in preclinical studies that 4PY directly triggers vascular inflammation which damages blood vessels and can lead to atherosclerosis over time.

Heart Disease 119

Heart Disease Heart Attack Heart attacks Atherosclerosis 119

Frontiers in Cardiovascular Medicine

FEBRUARY 23, 2024

Introduction The presence of non-coronary atherosclerosis (NCA) in patients with coronary artery disease is associated with a poor prognosis. The primary outcome was a combination of TIA/stroke, acute myocardial infarction, new revascularization procedure, or death.

Coronary Artery Bypass Graft 64

Coronary Artery Bypass Graft Atherosclerosis Peripheral Arterial Disease Coronary Artery Disease 64

Journal of the American Heart Association

DECEMBER 8, 2023

However, the association of FAR with large artery atherosclerosis (LAA) stroke is still unknown. Clinical outcomes included stroke recurrence, all‐cause death, poor functional outcome (modified Rankin Scale score 3–6), and dependence (modified Rankin Scale score 3–5). FAR was calculated as fibrinogen (g/L)/albumin (g/L).

Atherosclerosis 45

Atherosclerosis Outcomes Stroke Strokes 45

Stroke Journal

NOVEMBER 28, 2023

Stroke, Ahead of Print. Of all the participants at visit 4 (n=11 656), those who were unable to go through dental examination, or with prevalent ischemic stroke and CHD events, were excluded. BACKGROUND:Dental caries is a highly prevalent disease worldwide. 1.79]) and death (adjusted HR, 1.13 [95% CI, 1.01–1.26])

Heart Disease 73

Heart Disease Stroke Strokes Atherosclerosis 73

Medical Xpress - Cardiology

DECEMBER 9, 2024

People with type 2 diabetes have a higher risk of suffering a stroke, a heart attack and premature death due to atherosclerosis, but it has been unclear what the underlying mechanisms are.

Diabetes 92

Diabetes Plaque Heart Attack Heart attacks 92

CTVS

OCTOBER 30, 2024

Common examples of vascular disease are aneurysms (a dangerous bulge in an artery wall), atherosclerosis (plaque buildup in the… Source Vascular disease affects the body’s vast network of blood vessels, veins and arteries.

Aneurysm 52

Aneurysm Atherosclerosis Plaque Heart Disease 52

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP116-AWP116, February 1, 2024. Both lumen stenosis and plaque components were correlated with multiple or recurrent infarcts in this population.

Plaque 40

Plaque Atherosclerosis Stroke Strokes 40

Circulation

JANUARY 24, 2024

METHODS:The AHA, through its Epidemiology and Prevention Statistics Committee, continuously monitors and evaluates sources of data on heart disease and stroke in the United States and globally to provide the most current information available in the annual Statistical Update with review of published literature through the year before writing.

Heart Disease 81

Heart Disease Peripheral Arterial Disease Stroke Strokes 81

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP292-AWP292, February 1, 2025. Background:Intracranial atherosclerosis (ICAS) is a common stroke cause, with a recurrent stroke risk of up to 18% per year despite treatment advances. The primary outcome was the incidence of stroke. The weighted mean age was 63.7

Atherosclerosis 40

Atherosclerosis Stroke Strokes Hypertension 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP260-AWP260, February 1, 2025. Background:The mechanisms by which intracranial atherosclerosis (ICAS) contributes to large-vessel occlusion strokes (LVOS) remains unclear.

Atherosclerosis 40

Atherosclerosis Stroke Strokes Atrial Fibrillation 40

Stroke Journal

OCTOBER 18, 2023

Stroke, Volume 54, Issue 12 , Page 3165-3168, December 1, 2023. BACKGROUND:RICAMIS trial (The Remote Ischemic Conditioning for Acute Moderate Ischemic Stroke) has demonstrated efficacy of remote ischemic conditioning (RIC) in acute ischemic stroke. to 9.3%];P=0.12).

Atherosclerosis 40

Atherosclerosis Outcomes Stroke Strokes 40

Science Daily - Heart Disease

MARCH 13, 2024

Blockage of arterial blood vessels caused by atherosclerosis is largely responsible for heart attacks and strokes, which are the most common causes of death worldwide. The complex mechanisms that lead to pathological changes in the arteries are not yet fully understood.

Heart Attack 58

Heart Attack Heart attacks Stroke Strokes 58

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A41-A41, February 1, 2025. This is largely due to the Stenting and Aggressive Medical Management Therapy for Preventing Recurrent Stroke in Intracranial Arterial Stenosis (SAMMPRIS) trial results which featured a high periprocedural stroke rate.

Stroke 40

Stroke Strokes Stents Stent 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP300-ATP300, February 1, 2024. Background:Most ischemic strokes are caused by atherosclerosis. Apolipoprotein E (ApoE) regulates lipid metabolism, and its deficiency is associated with dyslipidemia and atherosclerosis. Poor dietary habits promote the onset of atherosclerosis.

Atherosclerosis 40

Atherosclerosis Risk Factors Diet Plaque 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP142-ATP142, February 1, 2024. Introduction:Perfusion imaging has been used to assess collateral status in patients with acute ischemic stroke secondary to anterior large-vessel occlusion. A relative CBF<30% was also obtained.

Atherosclerosis 40

Atherosclerosis Stroke Strokes Stenosis 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP203-AWP203, February 1, 2025. Evidence has shown that carotid artery geometries are independently associated with ipsilateral MCA atherosclerosis. Demographic data, risk factors and the history of ischemic stroke of all patients were recorded. 21.35), p<0.001).Conclusions:Both

Atherosclerosis 40

Atherosclerosis Stenosis Risk Factors BMI 40

Circulation

DECEMBER 28, 2023

Using mediation Mendelian randomization, we explored proteomic mediators of the effects of genetically proxied IL-6 signaling on coronary artery disease, large artery atherosclerotic stroke, and peripheral artery disease.

Atherosclerosis 49

Atherosclerosis Peripheral Arterial Disease Coronary Artery Disease Pharmacology 49

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A110-A110, February 1, 2025. Background:Recent studies have shown that the autonomic nervous system plays a crucial role in regulating the initiation and progression of atherosclerosis in peripheral arteries.

Atherosclerosis 40

Atherosclerosis Plaque Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A131-A131, February 1, 2024. The primary outcome was incident ischemic stroke. There were a total of 18 ischemic stroke events among those with LVI (6%) and 65 among those without LVI (3%). LV apical circumferential strain>-10% may be a novel and quantitative stroke risk factor.

Atherosclerosis 40

Atherosclerosis Stroke Strokes Atrial Fibrillation 40

DAIC

JANUARY 23, 2024

3 Patients with ASCVD are at a higher risk for major adverse cardiovascular events (MACE) including heart attack or myocardial infarction (MI), stroke, and cardiovascular (CV) death.4 1,6 Until recently atherosclerosis has been thought of as the result of passive lipid accumulation in the vessel wall. 4 In the U.S.

Cardiovascular Disease 111

Cardiovascular Disease Heart Attack Heart attacks Coronary Artery Disease 111

American College of Cardiology

JANUARY 10, 2024

The goal of the INSPIRES trial was to determine whether DAPT with clopidogrel and aspirin initiated within 72 hours of mild ischemic stroke or high-risk TIA was associated with decreased incidence of recurrent stroke compared with aspirin monotherapy.

Atherosclerosis 58

Atherosclerosis Stroke Strokes Article 58

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP139-AWP139, February 1, 2024. We hypothesized that intracranial atherosclerosis, which is seen predominantly in older patients, affects vasospasm risk in aSAH. This may suggest intracranial atherosclerosis may affect TCD velocities without any clinical correlation.

Atherosclerosis 40

Atherosclerosis Aneurysm Hemorrhage Outcomes 40

Science Daily - Stroke

NOVEMBER 2, 2023

Researchers have demonstrated the specific role microRNA plays in atherosclerosis -- and how it manages to intervene in this signaling pathway.

Atherosclerosis 40

Atherosclerosis Research 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP288-ATP288, February 1, 2025. Carotid atherosclerosis (CAS) is a critical precursor to atherosclerotic cardiovascular disease and is closely associated with the development and progression of conditions such as stroke and poor prognosis. 2021-KY-1289-001).Results:Among respectively.

Atherosclerosis 40

Atherosclerosis Plaque Stenosis Cardiovascular Disease 40

Journal of the American Heart Association

FEBRUARY 8, 2025

BackgroundAtrial fibrillation (AF) significantly increases the ischemic stroke risk. Cox regression models and competing risk survival analyses were used to assess incidence rates and hazard ratios (HRs) for ischemic stroke stratified by age groups. Among 47 239 participants (median followup: 21.1 The presence of AF yielded a 13.9

Atrial Fibrillation 45

Atrial Fibrillation Stroke Strokes Atherosclerosis 45

Frontiers in Cardiovascular Medicine

FEBRUARY 4, 2024

Background Carotid artery atherosclerosis is a major cause of ischemic stroke, and ischemic stroke is the leading cause of morbidity and mortality worldwide. Unfortunately, the reason for the build-up of atherosclerosis plaque is unknown. Moreover, there was an increased miRNA-29c level in patients with cerebral stroke.

Plaque 64

Plaque Diabetes Atherosclerosis Stroke 64

Frontiers in Cardiovascular Medicine

DECEMBER 5, 2024

The fundamental role of qualitative alterations of lipoproteins in the early development of atherosclerosis has been widely demonstrated. However, the corresponding studies are scarcer in the field of ischemic stroke, despite carotid arteriosclerosis progression underlies at least 20% of ischemic strokes.

Circulation 40

Circulation Stroke Strokes Atherosclerosis 40

DAIC

MARCH 31, 2025

The study, Effect of Colchicine on Progression of Known Coronary Atherosclerosis in Patients With Stable Coronary Artery Disease Compared To Placebo: The Ekstrom Trial, was presented at the American College of Cardiology 74th Annual Scientific Session and Expo ( ACC.25 These new data reinforce the use of LODOCO(colchicine, 0.5

Cardiovascular Disease 52

Cardiovascular Disease Plaque Coronary Artery Disease Heart Attack 52

Stroke: Vascular and Interventional Neurology

APRIL 24, 2024

Stroke: Vascular and Interventional Neurology, Ahead of Print. ICASLVO is a significant contributor to acute ischemic stroke, with varying prevalence rates across regions. ICASLVO is a significant contributor to acute ischemic stroke, with varying prevalence rates across regions.

Atherosclerosis 40

Atherosclerosis Ultrasound Stenosis Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP222-ATP222, February 1, 2025. Background:Symptomatic intracranial atherosclerotic disease carries a high stroke recurrence rate. Accurate prediction of stroke recurrence is critical for improving patient outcomes through timely and targeted interventions. Variables with p<0.05

Atherosclerosis 40

Atherosclerosis Stroke Strokes Stenosis 40

All About Cardiovascular System and Disorders

MAY 22, 2024

About a fifth of all ischemic strokes are attributed to embolization of ruptured atherosclerotic plaque from carotid arterial stenosis. But it has been difficult to predict which person with asymptomatic carotid artery stenosis is likely to progress to symptomatic carotid disease and stroke.

Stenosis 52

Stenosis Stroke Strokes Risk Factors 52