Stroke Journal

JANUARY 30, 2025

Introduction:The middle cerebral artery (MCA) is the most common site for inrtacranial atherosclerotic stenosis. Evidence has shown that carotid artery geometries are independently associated with ipsilateral MCA atherosclerosis. Stroke, Volume 56, Issue Suppl_1 , Page AWP203-AWP203, February 1, 2025. 21.35), p<0.001).Conclusions:Both

Atherosclerosis 40

Atherosclerosis Stenosis Risk Factors BMI 40

Stroke Journal

JUNE 26, 2024

Asymptomatic high-grade carotid stenosis is an important therapeutic target for stroke prevention. Advances in treatments against atherosclerosis have driven down the rates of stroke in patients managed without revascularization.

Stenosis 40

Stenosis Stent Stents Atherosclerosis 40

Stroke Journal

JANUARY 30, 2025

Background and Objectives:Left subclavian artery (LSA) is more prone to atherosclerosis than the right one. The study was designed to investigate whether aortic arch types (AAT) was associated with the lateralization of subclavian artery stenosis (SAS).Methods:In vs 2.4%, p < 0.001) and (any degree stenosis: 8.4%

Stenosis 40

Stenosis Aortic Atherosclerosis Risk Factors 40

DAIC

JUNE 10, 2024

“It marks a turning point in reporting of CCTA as it focuses on actual quantification of atherosclerosis.” The writing group shared that, despite these available measurements and guidelines, the field currently lacks standards for the quantitative image interpretation of and reporting of CCTA results.

Document 104

Document Coronary Artery Disease Stenosis Plaque 104

Heart BMJ

APRIL 15, 2024

Objective Aortic stenosis (AS) shares pathophysiological similarities with atherosclerosis including active inflammation. CT attenuation of perivascular adipose tissue provides a measure of vascular inflammation that is linked to prognosis and has the potential to be applied to the aortic valve.

Aortic valve 52

Aortic valve Aortic Stenosis Atherosclerosis 52

Journal of the American Heart Association

DECEMBER 8, 2023

BackgroundThe relationship between depression and subclinical coronary atherosclerosis in asymptomatic individuals is not clear. The degree and extent of subclinical coronary atherosclerosis were evaluated by coronary computed tomographic angiography, and ≥50% diameter stenosis was defined as significant. 2.03];P=0.450).

Coronary Artery Disease 40

Coronary Artery Disease Atherosclerosis Plaque Stenosis 40

DAIC

JANUARY 9, 2024

Through its AI capability, Cleerly ISCHEMIA determines the likely presence or absence of coronary vessel ischemia based on quantitative measures of atherosclerosis, stenosis, and significant vascular morphology from patients’ CCTA images.

Ischemia 119

Ischemia Heart Disease Coronary Artery Disease Atherosclerosis 119

Open Heart

MARCH 24, 2023

Our perspectives on aortic stenosis (AS) are changing. The pathophysiology of calcific AS (CAS) is complex, yet can be characterised similarly to that of atherosclerosis. Progressive remodelling involves lipid-protein complexes, with lipoprotein(a) being of particular interest for diagnostics and potential future treatment options.

Stenosis 52

Stenosis Aortic Aortic valve Biomarkers 52

Stroke Journal

FEBRUARY 1, 2024

Compared with contralateral carotid artery plaque, plaque burden at the ipsilateral carotid artery was much heavy, presented with a higher degree of stenosis, smaller lumen area (0.22±0.15 Both lumen stenosis and plaque components were correlated with multiple or recurrent infarcts in this population. of them were male.

Plaque 40

Plaque Atherosclerosis Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Carotid atherosclerosis (CAS) is a critical precursor to atherosclerotic cardiovascular disease and is closely associated with the development and progression of conditions such as stroke and poor prognosis. Stroke, Volume 56, Issue Suppl_1 , Page ATP288-ATP288, February 1, 2025.

Atherosclerosis 40

Atherosclerosis Plaque Stenosis Cardiovascular Disease 40

DAIC

FEBRUARY 13, 2024

The company reports that its clinically-proven, AI-based digital care platform works with coronary computed tomography angiography (CCTA) imaging to help clinicians precisely identify and define atherosclerosis earlier, enabling them to provide personalized, life-saving treatment plans for all patients throughout their care continuum.

Coronary Artery Disease 103

Coronary Artery Disease Ischemia Atherosclerosis Cardiovascular Imaging 103

Stroke Journal

JANUARY 30, 2025

Introduction:Elevated Low-Density-Lipoprotein Cholesterol (LDL-C) blood levels are a risk factor for atherosclerosis. For this study, acute symptomatic was defined as hemispheric ischemic stroke or retinal ischemia ipsilateral to the carotid stenosis, with symptom onset within 24 hours of admission. were asymptomatic and 40.2%

Stenosis 40

Stenosis Atherosclerosis Cholesterol Ischemia 40

DAIC

MAY 8, 2024

1 Atherosclerosis is a systemic disease that affects multiple vascular regions and is particularly severe in PAD patients, where up to 80 percent suffer from concurrent coronary artery disease (CAD), historically linked with a mortality rate exceeding 50 percent within five years.

Coronary Artery Disease 111

Coronary Artery Disease Chest Pain Ischemia Myocardial Infarction 111

Stroke Journal

JANUARY 30, 2025

Background:The uneven distribution of intracranial atherosclerotic stenosis (ICAS) along the internal carotid artery (ICA) had been described in early clinicopathological studies, yet related, large-scale data is lack despite the widespread utilization of angiography.

Stenosis 40

Stenosis Hospital Atherosclerosis Risk Factors 40

Stroke Journal

JANUARY 30, 2025

We aimed to investigate the association between VAH and atherosclerotic stenosis of subclavian artery (SA), vertebral artery (VA) and basilar artery (BA) based on digital subtraction angiography (DSA).Methods:In VAH and stenosis degree of the artery (i.e., p< 0.001) and basilar artery stenosis (BAS) (left VAH: OR 2.94, 95% CI 2.15-4.04,p<

Stenosis 40

Stenosis Atherosclerosis Risk Factors Stroke 40

Stroke: Vascular and Interventional Neurology

APRIL 24, 2024

This manuscript provides a comprehensive review of intracranial atherosclerosis (ICAS)related largevessel occlusion (ICASLVO) and its mimics, focusing on the challenges in diagnosis and the need for precise diagnostic methodologies, particularly in the context of endovascular therapy.

Atherosclerosis 40

Atherosclerosis Ultrasound Stenosis Stroke 40

Journal of the American Heart Association

JANUARY 19, 2024

BackgroundAortic stenosis has pathophysiological similarities with atherosclerosis, including the deposition of cholesterol‐containing lipoproteins. Journal of the American Heart Association, Ahead of Print. In multivariate analysis, low CCDR (hazard ratio, 2.21 [95% CI, 0.99–4.92],P=0.04)

Aortic valve 40

Aortic valve Cholesterol Aortic Stenosis 40

Frontiers in Cardiovascular Medicine

DECEMBER 14, 2023

Background Inflammation and lipid infiltration play crucial roles in the development of atherosclerosis. This study aimed to investigate the association between various complex indexes of blood cell types and lipid levels with the severity of coronary artery stenosis and their predictive value in coronary heart disease (CHD).

Heart Disease 64

Heart Disease Cholesterol Stenosis Atherosclerosis 64

Frontiers in Cardiovascular Medicine

APRIL 24, 2024

In this study, we test the assumption that miRNAs present in material acquired from plaques in patients undergoing surgery for atherosclerotic carotid artery stenosis are also expressed in circulating EVs obtained from the identical patients. EVs were isolated from serum by precipitation. EVs were isolated from serum by precipitation.

Plaque 52

Plaque Biomarkers Circulation Stenosis 52

Stroke: Vascular and Interventional Neurology

JANUARY 25, 2024

Most neurointerventionalists (91%) diagnose ICAS‐LVO after a continued or recurrent occlusion or by the presence of fixed focal stenosis after multiple mechanical thrombectomy attempts. However, in patients who achieved recanalization with a severe fixed focal stenosis, most (58%) recommended primary medical management.

Atherosclerosis 40

Atherosclerosis Angioplasty Stenosis Biomarkers 40

DAIC

MARCH 31, 2025

The study, Effect of Colchicine on Progression of Known Coronary Atherosclerosis in Patients With Stable Coronary Artery Disease Compared To Placebo: The Ekstrom Trial, was presented at the American College of Cardiology 74th Annual Scientific Session and Expo ( ACC.25

Cardiovascular Disease 52

Cardiovascular Disease Plaque Coronary Artery Disease Heart Attack 52

Stroke Journal

NOVEMBER 1, 2023

BACKGROUND:Inflammation contributes to atherosclerosis but is incompletely characterized in intracranial large artery stenosis (ICAS). We dichotomized ICAS as either ≥50% stenosis or not (including no ICAS). Stroke, Volume 54, Issue 12 , Page 3030-3037, December 1, 2023.

Stenosis 40

Stenosis Atherosclerosis Stroke Strokes 40

Frontiers in Cardiovascular Medicine

FEBRUARY 7, 2024

At the patient level, those with reduced CFR showed a significantly higher prevalence of diffused atherosclerosis (41% vs. 23%; P  < 0.001) and higher FAI (−75.5 HU In the patient-level analysis, obstructive CAD, diffused atherosclerosis, and FAI were independently linked with CFR. Results We detected a decrease in CFR (<2.5)

Coronary Artery Disease 64

Coronary Artery Disease Atherosclerosis Plaque Stenosis 64

Stroke Journal

JANUARY 30, 2025

Patients presenting intracranial atherosclerosis-related large vessel occlusion (ICAS-LVO) may benefit from performing an early bailout strategy after failed MT with conventional devices. ICAS-LVO was defined by fial angiographic stenosis &gt;50% or failed MT (eTICI0-2a) with no evidence of other underlying etiology (i.e

Atherosclerosis 40

Atherosclerosis Stroke Strokes Stenosis 40

DAIC

FEBRUARY 3, 2025

et al, Lipoprotein(a) in atherosclerotic cardiovascular disease and aortic stenosis: a European Atherosclerosis Society consensus statement , European Heart Journal, Volume 43, Issue 39, 14 October 2022, Pages 39253946 Koschinsky ML et al. 2022 Aug, 80 (9) 934946 Kronenberg F.

Cardiovascular Disease 52

Cardiovascular Disease Aortic valve Biomarkers Innovation 52

Stroke Journal

FEBRUARY 1, 2024

Inclusion criteria: patients with anterior circulation stroke with concomitant extracranial internal carotid artery (ICA) disease with 70-100% stenosis per NASCET criteria and patients who underwent computed tomography perfusion (CTP) before EVT.

Atherosclerosis 40

Atherosclerosis Stroke Strokes Stenosis 40

Dr. Smith's ECG Blog

MAY 20, 2024

There is an area of dense white in the middle of the circle consistent with atherosclerosis. They too have dense white masses consistent with coronary atherosclerosis. Or is it a very tight stenosis that does not allow enough flow to perfuse myocardium that has a high oxygen demand from severely elevated BP?

Chest Pain 126

Chest Pain Blood Pressure Ischemia STEMI 126

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionIntracranial atherosclerosis‐related large vessel occlusion (ICAS‐LVO) is a common cause of failed mechanical thrombectomy (MT) in acute ischemic stroke (AIS) [1]. Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. Overall, 40.6% reported an incidence of 6–10% of ICAS‐LVO during MT.

Atherosclerosis 40

Atherosclerosis Angioplasty Biomarkers Stents 40

Frontiers in Cardiovascular Medicine

FEBRUARY 5, 2024

Background Kounis syndrome is an acute coronary syndrome (ACS) caused by allergic reactions, including coronary artery spasm (type I) caused by allergies without coronary predisposing factors, pre-existing coronary atherosclerosis, and coronary artery disease.

Coronary Artery Disease 64

Coronary Artery Disease Electrocardiogram Myocardial Infarction Thrombosis 64

DAIC

MARCH 6, 2024

The CAD Staging System is a noninvasive imaging-based investigational software device that analyzes important and actionable features of coronary atherosclerosis, stenosis and ischemia. Food and Drug Administration ( FDA ) for its Coronary Artery Disease ( CAD ) Staging System.

Heart Disease 105

Heart Disease Heart Attack Heart attacks Technology 105

Stroke Journal

JANUARY 30, 2025

Background:Early detection of carotid artery (CA) conditions such as atherosclerosis and dissection are important as they represent major preventable causes of stroke. These patients had varying CA conditions (atherosclerosis, dissection, normal, etc.) Stroke, Volume 56, Issue Suppl_1 , Page AWMP107-AWMP107, February 1, 2025.

Stenosis 40

Stenosis Atherosclerosis Ultrasound Stroke 40

Stroke Journal

JANUARY 30, 2025

This study aims to validate T max delay and mismatch as predictors of 30-day ischemic stroke recurrence.Methods:This is a single-center study from a comprehensive stroke center including hospitalized patients with symptomatic intracranial arterial stenosis (50-99%) of the intracranial ICA and proximal middle cerebral artery (M1 or proximal M2).

Atherosclerosis 40

Atherosclerosis Stroke Strokes Stenosis 40

Stroke Journal

FEBRUARY 1, 2024

We defined the area stenosis as [1-LA/TVA]х100 (%) and the enhancing proportion as EA/TVAх100 (%). The causes of ICAD were atherosclerosis (69%), dissection (24%), vasculitis (3%), moyamoya disease (1%), and other causes (2%). Enhancement ratio of the enhancing lesion was also quantified. The median follow-up duration was 9.0

Atherosclerosis 40

Atherosclerosis Stenosis Stroke Strokes 40

Circulation

NOVEMBER 8, 2023

BACKGROUND:High circulating levels of Lp(a) (lipoprotein[a]) increase the risk of atherosclerosis and calcific aortic valve disease, affecting millions of patients worldwide. Circulation, Ahead of Print.

Aortic valve 40

Aortic valve Heart Disease Atherosclerosis Aortic 40

The British Journal of Cardiology

AUGUST 1, 2024

Genome-wide association and Mendelian randomisation studies have identified lipoprotein(a) (Lp[a]) as an emerging risk factor for calcific aortic stenosis and a causal risk factor for atherosclerotic cardiovascular disease (ASCVD) in different ethnicities. HEART UK recommends Lp(a) measurement in specific ‘at-risk’ cohorts.

Risk Factors 40

Risk Factors Atherosclerosis Laboratory Stenosis 40

Stroke Journal

JANUARY 30, 2025

This is largely due to the Stenting and Aggressive Medical Management Therapy for Preventing Recurrent Stroke in Intracranial Arterial Stenosis (SAMMPRIS) trial results which featured a high periprocedural stroke rate.

Stroke 40

Stroke Strokes Stent Stents 40

Frontiers in Cardiovascular Medicine

MAY 21, 2024

Doppler ultrasonography performed a day after the operation showed an increase in systolic blood velocity, with no observed urine output and raising a suspicion of arterial anastomotic stenosis. The transplant renal artery lesion was intervened with a stent.

Transplant 52

Transplant Ultrasound Plaque Atherosclerosis 52