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Atherosclerosis (ASVD) remains a leading driver of cardiovascular disease (CVD), a global health challenge that claims millions of lives each year. Explore actionable, evidence-based strategies to combat traditional and emerging riskfactors, with a focus on precision approaches and primordial prevention.
This study aimed to evaluate the riskfactors associated with LV mass and subclinical coronary atherosclerosis, in an Asian population free of baseline cardiovascular disease. Individuals were stratified based on LVMI and the presence of CAC, and intergroup differences in riskfactors were analysed.
Our risk of developing atherosclerosis -- 'furring' of the arteries -- can begin much earlier in life than was previously thought, highlighting the need to keep cholesterol levels low even when we are young, new research has discovered.
And plaque in your coronary arteries is the result of exposure to riskfactors over time. These individuals then must have had one or more riskfactors for a long time prior to their heart attack. The answer: RiskFactors. But wouldn’t such riskfactors have been obvious?
Nearly 80% of patients with lung cancer had detectable atherosclerosis on their cancer staging CT scans and other cardiovascular riskfactors were common, offering an opportunity for earlier cardiac testing and riskfactor modification, according to a new study.
Do autoimmune diseases independently correlate with coronary atherosclerosis and atherosclerotic cardiovascular disease (ASCVD) risk, and do traditional cardiovascular riskfactors modulate the risk?
Preeclampsia (PE) and type 1 diabetes (T1D) are significant riskfactors for cardiovascular disease (CVD), but their combined effect on atherosclerosis progression has not been fully explored. This study aimed.
Atherosclerosis is the major contributor to cardiovascular mortality worldwide. Diet-induced metabolic abnormalities including obesity, hyperglycemia, dyslipidemia, insulin resistance (IR), and non-alcoholic fatty liver disease are considered atherogenic riskfactors.
Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) in Madrid have found that one of the most potent genetic riskfactors for Alzheimer's disease, apolipoprotein E4 (APOE4), is also associated with an increased risk of developing subclinical atherosclerosis in middle age.
METHODS:The AHA, through its Epidemiology and Prevention Statistics Committee, continuously monitors and evaluates sources of data on heart disease and stroke in the United States and globally to provide the most current information available in the annual Statistical Update with review of published literature through the year before writing.
Metal exposure from environmental pollution is associated with increased calcium buildup in the coronary arteries at a level comparable to traditional riskfactors, according to a new study.
Methods We retrospectively analysed data from 5188 participants in the AtherosclerosisRisk in Communities Study who were free from heart failure at baseline, including 802 individuals with a history of myocardial infarction. fold higher risk compared with those with lower values. m/s had a 2.10-fold
Introduction:Prior studies have shown the association between oral infection, white matter hyperintensity (WMH), a marker of cerebral small vessel disease (CSVD), and asymptomatic intracranial atherosclerosis (ICAS). However, the impact of preventative oral behavior such as dental flossing is unknown.
Although the entire vascular bed is constantly exposed to the same riskfactors, atherosclerosis manifests a distinct intra-individual pattern in localization and progression within the arterial vascular bed.
This study aimed to evaluate atherosclerosis as comorbidity by measuring the carotid (bulb and common carotid artery) Carotid intima-media thickness in COPD-diagnosed patients and to evaluate the relationship.
Aging is known to be a riskfactor for the biological changes that create the dangerous buildup of plaque in arteries called atherosclerosis, and aging also induces a buildup of memory CD8 T cells, a type of immune cell, in mice and humans.
Clonal hematopoiesis of indeterminate potential (CHIP) has emerged as a previously unrecognized, potent, age-related, and common riskfactor for atherosclerosis. The increased risk of developing hematologic malignancy does not, on its own, explain excess mortality in individuals with CHIP.
Subclinical hypothyroidism (SCH) remains a controversial riskfactor for CVD. This review examines the associations between SCH and dyslipidemia, carotid intima-media thickness (C-IMT), cardiac dysfunction, and cardiovascular event risk.
A study carried out at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) in Madrid, Spain provides crucial information about the effect of cardiometabolic riskfactors and subclinical atherosclerosis on the network of microvessels that irrigate the heart in symptom-free middle-aged individuals.
This unmet clinical need for pharmacotherapeutic strategies tailored specifically to AS has spurred contemporary efforts to unravel the development of this disease from atherosclerosis.
Background:Most ischemic strokes are caused by atherosclerosis. Apolipoprotein E (ApoE) regulates lipid metabolism, and its deficiency is associated with dyslipidemia and atherosclerosis. Poor dietary habits promote the onset of atherosclerosis. Stroke, Volume 55, Issue Suppl_1 , Page ATP300-ATP300, February 1, 2024.
High-density lipoprotein (HDL) emerged as a protective factor against CAS, with total cholesterol and HDL levels proving significant predictors.ConclusionsThis research illuminates the riskfactors linked to CAS and introduces a validated risk scoring tool, highlighted by the logistic classifier's consistent performance during training and testing.
Methods At baseline, adults aged 45–84 years, free of CVD, in the Multi-Ethnic Study of Atherosclerosis had HGF and ECC measured by ELISA and cardiac CT scan, respectively. We used Poisson and linear mixed-effects regression models to estimate the association between HGF and ECC, adjusted for sociodemographic and CVD riskfactors.
CCR5, a chemokine receptor, has been associated with both immunosuppressive and inflammatory phenotypes, however, the possible role of CCR5 pertaining to MDSCs in the development of atherosclerosis has not been elucidated yet. Possibly this dysfunctionality contributes to the development and progression of CVD including atherosclerosis.
The risk of atherosclerotic cardiovascular disease (ASCVD) is approximately twofold higher for South Asian (SA) adults than for adults from other racial and ethnic groups. Type 2 diabetes mellitus (T2DM) is a highly prevalent riskfactor that likely contributes to this disparity.
Nature Reviews Cardiology, Published online: 17 September 2024; doi:10.1038/s41569-024-01081-3 New research suggests that the presence of clonal haematopoiesis is unidirectionally associated with the development of atherosclerosis and that colchicine holds potential therapeutic value.
Both insulin resistance and hyperglycemia are important riskfactors for atherosclerosis. While the characteristics of atherosclerosis are obviously different according to established diabetes, little has been.
Several cardiovascular riskfactors, such as advanced age and smoking history, are prevalent among lung cancer patients at the time of the diagnosis and increase their risk of future heart disease, according to a new study being presented at ACC's Advancing the Cardiovascular Care of the Oncology Patient course.
Evidence has shown that carotid artery geometries are independently associated with ipsilateral MCA atherosclerosis. Demographic data, riskfactors and the history of ischemic stroke of all patients were recorded. However, whether the role of the blood flow dynamics underlies this association remains uncertain.
Lp(a) is emerging as an important, yet under-recognized, potential riskfactor for cardiovascular disease due to its ability to promote the development of plaques within artery walls, clot formation and aortic valve calcification. The development of the Tina-quant Lipoprotein (a) Gen.2 2022 Aug, 80 (9) 934946 Kronenberg F.
Findings from earlier research have established that insulin resistance (IR) is implicated in atherosclerosis progression, representing a noteworthy riskfactor for cardiovascular disease (CVD). Recently, the.
BackgroundThe relationship between depression and subclinical coronary atherosclerosis in asymptomatic individuals is not clear. The degree and extent of subclinical coronary atherosclerosis were evaluated by coronary computed tomographic angiography, and ≥50% diameter stenosis was defined as significant. 2.03];P=0.450).
Dysglycaemia is a known riskfactor for cardiovascular disease and microcirculatory dysfunction is associated with an increased cardiovascular disease risk. The aim of this study was to investigate the prevale.
When it comes to cardiovascular disease, two of the biggest riskfactors we must consider are: ApoB concentration - A measure of the number of circulating lipid particles. Visceral Fat & Insulin Resistance - The amount of fat in your abdominal cavity and major organs and how it influences your risk of insulin resistance.
Here’s what you can expect at the biggest conference in cardiorenal metabolic health, the 19th Annual Cardiometabolic Congress (CMHC), DECODING THE CONSTELLATION of Cardiometabolic Health and RiskFactors. Michos, MD, MHS, FACC, FAHA, FASE, FASPC ; famed hypertension expert Keith C.
The prevalence of HF riskfactors was high: hypertension, 61.9%; former or current smoking, 53.7%; obesity 34.8%; diabetes; 24.7%; and chronic kidney disease; 22%. Results:Median age was 73 (25th–75th percentile 67–81) years, 53.2% were female, 25.6% were Black, 12.8% were Chinese, and 40.0% were White. were female, 25.6% were White.
Genome-wide association and Mendelian randomisation studies have identified lipoprotein(a) (Lp[a]) as an emerging riskfactor for calcific aortic stenosis and a causal riskfactor for atherosclerotic cardiovascular disease (ASCVD) in different ethnicities.
The CAD Staging System is a noninvasive imaging-based investigational software device that analyzes important and actionable features of coronary atherosclerosis, stenosis and ischemia. Food and Drug Administration ( FDA ) for its Coronary Artery Disease ( CAD ) Staging System.
Any atherosclerotic plaque is bad, and its presence portends a worse prognosis if modifiable riskfactors like hypertension and smoking are not addressed.
Background and aimsUltrasound derived carotid intima-media thickness (cIMT) is valuable for cardiovascular risk stratification. Age, blood pressure, and anthropometric related variables were the strongest predictors of cIMT with fat-free mass index of the truncal region being the strongest predictor among adiposity measurements.
IntroductionCerebrovascular disease (CVD), particularly carotid artery atherosclerosis, contributes substantially to global morbidity and mortality. The ability to precisely detect atherosclerosis is crucial, as it directly influences patient management, including decisions regarding surgical interventions.
This condition, called atherosclerosis, narrows the arteries, restricting blood flow and increasing the risk of heart attacks and strokes. Increased Risk of Aneurysms : Chronic high blood pressure can weaken the walls of your arteries, leading to bulging areas known as aneurysms.
Background:Intracranial Atherosclerosis (ICAS) leads to stroke by perforator disease, artery to artery embolism, and impaired distal flow/perfusion. We used univariate and multivariable Cox regression analyses to determine the association between riskfactors, treatment strategies, perfusion delay at Tmax4 sec and 6 sec thresholds.
At the patient level, those with reduced CFR showed a significantly higher prevalence of diffused atherosclerosis (41% vs. 23%; P < 0.001) and higher FAI (−75.5 HU In the patient-level analysis, obstructive CAD, diffused atherosclerosis, and FAI were independently linked with CFR. Results We detected a decrease in CFR (<2.5)
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