Remove Atherosclerosis Remove Plaque Remove Stenosis
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Identification of microRNA biomarkers simultaneously expressed in circulating extracellular vesicles and atherosclerotic plaques

Frontiers in Cardiovascular Medicine

The early detection of plaques by circulating biomarkers is highly clinically relevant to prevent the occurrence of major complications such as stroke or heart attacks. miRNA expression profiles of serum-derived EVs were obtained by small RNA sequencing and in plaque material simultaneously acquired from patients.

Plaque 52
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Link Between Clonal Hematopoiesis and Stroke in Carotid Stenosis

All About Cardiovascular System and Disorders

About a fifth of all ischemic strokes are attributed to embolization of ruptured atherosclerotic plaque from carotid arterial stenosis. But it has been difficult to predict which person with asymptomatic carotid artery stenosis is likely to progress to symptomatic carotid disease and stroke. J Am Coll Cardiol. 2024.03.389.

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William M. Feinberg Lecture: Asymptomatic Carotid Stenosis: Current and Future Considerations

Stroke Journal

Asymptomatic high-grade carotid stenosis is an important therapeutic target for stroke prevention. Advances in treatments against atherosclerosis have driven down the rates of stroke in patients managed without revascularization.

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Depression and Subclinical Coronary Atherosclerosis in Adults Without Clinical Coronary Artery Disease

Journal of the American Heart Association

BackgroundThe relationship between depression and subclinical coronary atherosclerosis in asymptomatic individuals is not clear. The degree and extent of subclinical coronary atherosclerosis were evaluated by coronary computed tomographic angiography, and ≥50% diameter stenosis was defined as significant. 2.03];P=0.450).

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New Expert Consensus Turns Cardiac CT Imaging into Measurable Standards

DAIC

“It marks a turning point in reporting of CCTA as it focuses on actual quantification of atherosclerosis.” The writing group shared that, despite these available measurements and guidelines, the field currently lacks standards for the quantitative image interpretation of and reporting of CCTA results.

Document 104
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Relationship between peri-coronary inflammation and coronary vascular function in patients with suspected coronary artery disease

Frontiers in Cardiovascular Medicine

At the patient level, those with reduced CFR showed a significantly higher prevalence of diffused atherosclerosis (41% vs. 23%; P  < 0.001) and higher FAI (−75.5 HU In the patient-level analysis, obstructive CAD, diffused atherosclerosis, and FAI were independently linked with CFR. Results We detected a decrease in CFR (<2.5)

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Case Report: Kounis syndrome due to cryptopteran bite

Frontiers in Cardiovascular Medicine

Background Kounis syndrome is an acute coronary syndrome (ACS) caused by allergic reactions, including coronary artery spasm (type I) caused by allergies without coronary predisposing factors, pre-existing coronary atherosclerosis, and coronary artery disease.