Frontiers in Cardiovascular Medicine

MARCH 4, 2024

The complex development of atherosclerosis manifests as intimal plaque which occurs in the presence or absence of traditional risk factors. CCTA also has the potential to de-risk clinical endpoint-based trials both financially and by enrichment of participants at higher likelihood of MACE.

Plaque 59

Plaque Coronary Artery Disease Blood Pressure Cardiovascular Disease 59

MIBHS

FEBRUARY 15, 2025

Artery Damage : Hypertension damages the inner lining of your arteries, making them less elastic and more prone to plaque buildup. This condition, called atherosclerosis, narrows the arteries, restricting blood flow and increasing the risk of heart attacks and strokes.

Blood Pressure 52

Blood Pressure Hypertension Chest Pain ACE Inhibitor 52

Circulation

NOVEMBER 11, 2024

CCR5, a chemokine receptor, has been associated with both immunosuppressive and inflammatory phenotypes, however, the possible role of CCR5 pertaining to MDSCs in the development of atherosclerosis has not been elucidated yet. Possibly this dysfunctionality contributes to the development and progression of CVD including atherosclerosis.

Atherosclerosis 40

Atherosclerosis Plaque Coronary Artery Disease Diet 40

DAIC

FEBRUARY 3, 2025

Lp(a) is emerging as an important, yet under-recognized, potential risk factor for cardiovascular disease due to its ability to promote the development of plaques within artery walls, clot formation and aortic valve calcification. The development of the Tina-quant Lipoprotein (a) Gen.2 2022 Aug, 80 (9) 934946 Kronenberg F.

Cardiovascular Disease 52

Cardiovascular Disease Aortic valve Biomarkers Innovation 52

Journal of the American Heart Association

DECEMBER 8, 2023

BackgroundThe relationship between depression and subclinical coronary atherosclerosis in asymptomatic individuals is not clear. The degree and extent of subclinical coronary atherosclerosis were evaluated by coronary computed tomographic angiography, and ≥50% diameter stenosis was defined as significant. 2.03];P=0.450).

Coronary Artery Disease 40

Coronary Artery Disease Atherosclerosis Plaque Stenosis 40

NEJM Journal Watch - Cardiology

OCTOBER 24, 2024

Any atherosclerotic plaque is bad, and its presence portends a worse prognosis if modifiable risk factors like hypertension and smoking are not addressed.

Atherosclerosis 40

Atherosclerosis Plaque Risk Factors Hypertension 40

Frontiers in Cardiovascular Medicine

FEBRUARY 7, 2024

At the patient level, those with reduced CFR showed a significantly higher prevalence of diffused atherosclerosis (41% vs. 23%; P  < 0.001) and higher FAI (−75.5 HU In the patient-level analysis, obstructive CAD, diffused atherosclerosis, and FAI were independently linked with CFR. Results We detected a decrease in CFR (<2.5)

Coronary Artery Disease 64

Coronary Artery Disease Atherosclerosis Plaque Stenosis 64

Dr. Smith's ECG Blog

MAY 20, 2024

The scan also showed “scattered coronary artery plaques”. __ Smith comment 1 : the appropriate management at this point is to lower the blood pressure (lower afterload, which increases myocardial oxygen demand). There is an area of dense white in the middle of the circle consistent with atherosclerosis. The blue circle shows the LCx.

Chest Pain 124

Chest Pain Blood Pressure Ischemia STEMI 124

Dr. Smith's ECG Blog

NOVEMBER 15, 2023

MINOCA may be due to: coronary spasm, coronary microvascular dysfunction, plaque disruption, spontaneous coronary thrombosis/emboli , and coronary dissection; myocardial disorders, including myocarditis, takotsubo cardiomyopathy, and other cardiomyopathies. See "Mechanisms of acute coronary syndromes related to atherosclerosis".)

Coronary Angiogram 109

Coronary Angiogram Plaque Thrombosis STEMI 109

Stroke Journal

FEBRUARY 1, 2024

Background:Intracranial Atherosclerosis (ICAS) leads to stroke by perforator disease, artery to artery embolism, and impaired distal flow/perfusion. While medical treatment is likely to stabilize atherosclerotic plaques, it is unlikely to improve distal perfusion in the acute setting. The study outcome is recurrent ischemic stroke.

Atherosclerosis 40

Atherosclerosis Embolism Plaque Stroke 40

Journal of the American Heart Association

MARCH 27, 2025

Compared with healthy vascular aging, arteriosclerosis and atherosclerosis clusters showed a graded positive association with cardiac troponin I quintiles, independent of traditional risk factors.

Atherosclerosis 40

Atherosclerosis Plaque Risk Factors 40

Frontiers in Cardiovascular Medicine

MAY 21, 2024

Angiography showed a donor renal artery dissection distal to the moderately stenosed anastomosis site with calcified atherosclerotic plaque confirmed by IVUS. Our case showed that endovascular intervention can replace surgery to repair very early vascular complications such as dissection and help patients avoid high-risk operations.

Transplant 52

Transplant Ultrasound Plaque Atherosclerosis 52

Heart BMJ

MARCH 22, 2024

Immune-mediated inflammatory diseases (IMIDs) are recognised risk factors for accelerated atherosclerotic cardiovascular disease (CVD), particularly in younger individuals and women who lack traditional CVD risk factors.

Plaque 40

Plaque Atherosclerosis Risk Factors Angina 40

Circulation

JANUARY 15, 2024

Coronary artery calcification (CAC) accompanies the development of advanced atherosclerosis. Nevertheless, the relationship between CAC and the susceptibility of a plaque to provoke a thrombotic event remains incompletely understood. This review summarizes the current understanding and literature on CAC.

Coronary Artery Disease 45

Coronary Artery Disease Atherosclerosis Laboratory Plaque 45

Stroke Journal

JUNE 26, 2024

For decades, the ACAS (Asymptomatic Carotid Atherosclerosis Study) and ACST (Asymptomatic Carotid Surgery Trial) trials provided most of the evidence supporting endarterectomy for patients with asymptomatic high-grade stenosis who were otherwise good candidates for surgery. Stroke, Ahead of Print.

Stenosis 40

Stenosis Stents Stent Atherosclerosis 40

Stroke Journal

NOVEMBER 9, 2023

The identification of a variant in theHDAC9gene as a risk factor for large-artery atherosclerotic stroke, and subsequently coronary artery disease, has opened novel treatment pathways for stroke and more widely atherosclerotic disease. Stroke, Volume 54, Issue 12 , Page 3182-3189, December 1, 2023.

Stroke 40

Stroke Strokes Atherosclerosis Coronary Artery Disease 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionAtherosclerosis, the hardening and narrowing of the arteries, occurs due to the buildup of plaque on the inner walls of the arteries which can result in reduced blood flow to the organs and tissues. Risk factors such as smoking, chronic kidney disease, and aging can contribute to plaque formation.

Risk Factors 40

Risk Factors Blood Pressure Chest Pain Plaque 40

MIBHS

JULY 31, 2024

Sustained inflammation can damage your blood vessels, leading to atherosclerosis (plaque buildup) and increasing your risk of heart attack and stroke. This can lead to chest pain (angina) and increase your risk of heart attack or stroke, especially if you already have underlying heart disease.

Blood Pressure 52

Blood Pressure Heart Attack Heart attacks Heart Rhythm 52

Stroke Journal

JANUARY 30, 2025

Introduction:Mechanical thrombectomy (MT) devices were fundamentally designed for the treatment of cardioembolic (CE) strokes despite that 10-20% of large vessel occlusions (LVO) are caused by large artery atherosclerosis (LAA), which may not respond comparably. p&lt;0.0001), and ICA bulb plaque with high-risk features (87.9%

Atrial Fibrillation 40

Atrial Fibrillation Plaque Atherosclerosis Stroke 40

Dr. Smith's ECG Blog

MAY 19, 2020

If the arrest was caused by acute MI due to plaque rupture, then the diagnosis is MINOCA. Here is my comment on MINOCA: "Non-obstructive coronary disease" does not necessarily imply "no plaque rupture with thrombus." They often cannot even be recognized as culprits, as fissured or ulcerated plaque. FFR can be useful.

Defibrillator 52

Defibrillator Circulation Plaque Cardiac Arrest 52

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

However, CTA head and neck 4 days later demonstrated 90 percent stenosis of the mid left V2 at the C3‐4 level and a 75‐90 percent stenosis of the left mid V2 segment at the C5‐6 level (hard and soft plaque in these areas). Timely diagnosis is imperative, as decompressive surgery can be curative.

Stenosis 40

Stenosis Peripheral Arterial Disease Pacemaker Atherosclerosis 40

GEMMS

NOVEMBER 22, 2023

Risk factors for cardiovascular disease Understanding the risk factors for cardiovascular disease is crucial for maintaining optimal cardiovascular health. While some risk factors, such as age and family history, cannot be changed, others are within our control.

Blood Pressure 52

Blood Pressure Cholesterol Diet Exercise 52

Cardiometabolic Health Congress

JANUARY 15, 2025

While advances in treatment have reduced mortality in some regions, the atherosclerosis prevention remains challenging. This shift results from an epidemiologic transition: as infectious diseases decline, chronic conditions like atherosclerosis dominate.

Atherosclerosis 59

Atherosclerosis Plaque Myocardial Infarction Risk Factors 59

Dr. Smith's ECG Blog

JULY 31, 2013

No thromboembolism risks, not pleuritic, no radiation to the back. No cardiac risk factors, no cocaine use. Nevertheless, even young people have atherosclerosis and plaque rupture. History: Onset of CP 2.5 hours prior to ED arrival. Tight and pressure, radiates to right arm, + nausea, + SOB.

Chest Pain 52

Chest Pain Aneurysm STEMI Ischemia 52

DAIC

MARCH 31, 2025

mg reduces the risk of major adverse cardiovascular events (MACE) and supports its use in the treatment of cardiovascular disease. mg)has potential to directly reduce inflammation, which plays a substantial role in the formation and progression of atherosclerotic plaque leading to heart disease, said Matthew J.

Cardiovascular Disease 52

Cardiovascular Disease Plaque Coronary Artery Disease Heart Attack 52

DAIC

JULY 18, 2024

This registry will aim to provide world-wide physicians the most accurate information on coronary plaque to improve cardiovascular risk prediction and support the selection of patient-specific treatment,” said Dr. De Cecco. Márton Kolossváry (Gottsegen National Cardiovascular Center, Budapest, Hungary).

Plaque 105

Plaque Heart Attack Heart attacks Cardiovascular Disease 105

Dr. Paddy Barrett

FEBRUARY 14, 2025

The pathology that causes heart disease (atherosclerosis) is, by definition, the abnormal retention of a cholesterol particle in the artery wall. A heart attack is when that plaque ruptures and stops blood flow down the artery. But other factors also play a role. 1 ” Good question.

Cholesterol 114

Cholesterol Heart Disease Heart Attack Heart attacks 114

Frontiers in Cardiovascular Medicine

FEBRUARY 8, 2024

Objective Assessing the impact of lumbar disc herniation (LDH) on the plaque burden of coronary atherosclerosis is our objective. Gensini scores were calculated to assess the plaque burden of coronary. Logistic analysis was used to examine potential risk variables linked to the Gensini score.

Plaque 59

Plaque Angina Myocardial Infarction Risk Factors 59

Dr. Paddy Barrett

JUNE 7, 2024

Heart disease is the presence of plaque or atherosclerosis in the coronary arteries. Over a long enough time horizon, pretty much everyone will develop a significant amount of plaque and have a heart attack. We have very strong evidence to support the idea that the more plaque you have, the greater your risk of a heart attack 1.

Heart Disease 96

Heart Disease Heart Attack Heart attacks Plaque 96

MIBHS

FEBRUARY 28, 2025

Heart disease remains one of the leading causes of death worldwide, often attributed to a mix of lifestyle choices, environmental factors, and genetic predispositions. This blog explores how genetics influence heart health and whether mitigating these inherited risks is possible. Can You Prevent Heart Disease if Its in Your Genes?

Genetic predisposition 52

Genetic predisposition Heart Disease Cholesterol Blood Pressure 52

Dr. Paddy Barrett

SEPTEMBER 20, 2024

When we say heart disease, what we really mean is plaque in the artery wall. This Is Known As Atherosclerosis. The fundamental cause of atherosclerosis is when a cholesterol particle crosses into the artery wall from the bloodstream, gets stuck, and sets off an inflammatory process 1. No atherosclerosis. No heart attacks.

Heart Disease 111

Heart Disease Cholesterol Atherosclerosis Heart Attack 111

Dr. Paddy Barrett

APRIL 5, 2024

Primordial prevention is changing the environment around you so you do not develop the risk factors for heart disease and, by extension, do not get the disease early in life. Blood Pressure Control High blood pressure is the risk factor associated with the greatest number of deaths worldwide. J Am Heart Assoc.

Heart Disease 119

Heart Disease Coronary Artery Disease Heart attacks Heart Attack 119

Cardiometabolic Health Congress

JUNE 20, 2024

The EAS 2024 Congress (May 26-29, 2024) has concluded, providing critical insights into atherosclerosis and related vascular disease. Giovanna Liuzzo (Italy) revealed that advancements in noninvasive imaging recently allow for direct visualization of coronary atherosclerotic plaques. Here are some notable highlights: Prof.

Atherosclerosis 59

Atherosclerosis Cardiovascular Disease Coronary Artery Disease Myocardial Infarction 59

Dr. Paddy Barrett

JANUARY 23, 2024

However, most adults will start to develop advanced plaque in their coronary arteries early in life. By age 66, more than half of all females will have evidence of advanced plaque in their coronary arteries, as seen on a CT calcium score. Coronary atherosclerosis, as evidenced by an abnormal CAC score, is a measure of advanced plaque.

Heart Disease 105

Heart Disease Blood Pressure Dementia Atherosclerosis 105

Dr. Paddy Barrett

OCTOBER 4, 2024

To understand why the answer is always ‘Now’, I want to highlight three key points and then point to the evidence that supports the idea that reducing risk early is always better. Everyone starts with no plaque in the coronary arteries, but over a long enough time frame, everyone develops plaque in their coronary arteries.

Heart Disease 104

Heart Disease Plaque Cholesterol Risk Factors 104

Physiologically Speaking

APRIL 10, 2024

people from the general population), coronary artery calcium scores (CACS) are higher, indicating more calcification and the presence of atherosclerotic plaques. Calcified plaques are known to be more stable and less prone to rupture and lead to a heart attack. When comparing athletes to control groups (i.e., hours per week).

Atherosclerosis 52

Atherosclerosis Plaque Exercise Cardiovascular Disease 52

Journal of the American Heart Association

APRIL 7, 2025

BackgroundCardiovascular disease (CVD) is a leading cause of death in women with systemic lupus erythematosus (SLE) due to accelerated atherosclerosis that is not predicted by established CVD risk scores. CVD risk was assessed using QRISK3 (which includes SLE diagnosis as a risk factor) and Framingham Risk Score.

Atherosclerosis 40

Atherosclerosis Ultrasound Plaque Risk Factors 40