Frontiers in Cardiovascular Medicine

MARCH 4, 2024

The complex development of atherosclerosis manifests as intimal plaque which occurs in the presence or absence of traditional risk factors. Atherosclerotic coronary artery disease (CAD) is the causal pathological process driving most major adverse cardiovascular events (MACE) worldwide.

Plaque 59

Plaque Coronary Artery Disease Blood Pressure Cardiovascular Disease 59

Circulation

DECEMBER 17, 2024

However, the role of METTL4-mediated mitoepigenetic regulation in atherosclerosis is still unknown. We explored the mechanism of METTL4 involvement in atherosclerosis usingMettl4Mac-KO-Apoe-/-andMettl4MUT-Apoe-/-mice and cell models, as well as bone marrow transplantation.

Atherosclerosis 40

Atherosclerosis Transplant Plaque Pharmacology 40

Journal of Cardiovascular Pharmacology

FEBRUARY 28, 2024

Atherosclerosis is an insidious and progressive inflammatory disease characterized by the formation of lipid-laden plaques within the intima of arterial walls with potentially devastating consequences. However, despite a heterogenous substrate underlying coronary thrombosis, treatment remains identical.

Plaque 40

Plaque Thrombosis Atherosclerosis Article 40

Journal of Cardiovascular Pharmacology

NOVEMBER 26, 2023

Nevertheless, the correlation between ISNA and the progression of untreated coronary segments affected by native atherosclerosis remains incompletely investigated. Nevertheless, the correlation between ISNA and the progression of untreated coronary segments affected by native atherosclerosis remains incompletely investigated.

Atherosclerosis 40

Atherosclerosis Stents Stent Plaque 40

Dr. Paddy Barrett

APRIL 5, 2024

Effect of intensive compared with moderate lipid-lowering therapy on progression of coronary atherosclerosis: a randomized controlled trial. Effect of very high-intensity statin therapy on regression of coronary atherosclerosis: the ASTEROID trial. 2004 Mar 3;291(9):1071-80. 4 ASTEROID Investigators. 2006 Apr 5;295(13):1556-65.

Heart Disease 119

Heart Disease Coronary Artery Disease Heart attacks Heart Attack 119

DAIC

JANUARY 23, 2024

Atherosclerotic cardiovascular disease (ASCVD), caused by plaque buildup in arterial walls, is one of the leading causes of disability and death worldwide.1,2 1,6 Until recently atherosclerosis has been thought of as the result of passive lipid accumulation in the vessel wall. 4 In the U.S.

Cardiovascular Disease 111

Cardiovascular Disease Heart Attack Heart attacks Coronary Artery Disease 111

DAIC

MAY 16, 2024

PAD is a serious, progressive cardiovascular disease primarily caused by a buildup of fatty plaque in the blood vessels, or atherosclerosis. This plaque narrows the blood vessels and reduces blood flow to the legs and feet, which may significantly impair physical function, walking performance and quality of life.

Peripheral Arterial Disease 105

Peripheral Arterial Disease Exercise Ischemia Quality of Life 105