Atherosclerosis and Peripheral Arterial Disease

Challenges and opportunities in the management of type 2 diabetes in patients with lower extremity peripheral artery disease: a tailored diagnosis and treatment review

Cardiovascular Diabetology

JUNE 25, 2024

Lower extremity peripheral artery disease (PAD) often results from atherosclerosis, and is highly prevalent in patients with type 2 diabetes mellitus (T2DM). Individuals with T2DM exhibit a more severe manifes.

Peripheral Arterial Disease

Peripheral Arterial Disease Diabetes Atherosclerosis

New Guidelines on Peripheral Artery Disease Issued by American Heart Association, American College of Cardiology and Leading Medical Societies

DAIC

MAY 16, 2024

A new joint guideline from the American Heart Association (AHA), the American College of Cardiology (ACC) and nine other medical societies reports early diagnosis and treatment of peripheral artery disease is essential to improve outcomes and reduce amputation risk, heart attack, stroke and death for people with Peripheral Artery Disease (PAD).

Peripheral Arterial Disease

Peripheral Arterial Disease Exercise Quality of Life Ischemia

Scientists find cancer-like features in atherosclerosis, spurring opportunity for new treatment approaches

Science Daily - Heart Disease

APRIL 30, 2024

Researchers have discovered that the smooth muscle cells that line the arteries of people with atherosclerosis can change into new cell types and develop traits similar to cancer that worsen the disease.

Atherosclerosis

Atherosclerosis Cancer Peripheral Arterial Disease Coronary Artery Disease

Non-coronary atherosclerosis: a marker of poor prognosis in patients undergoing coronary artery bypass surgery

Frontiers in Cardiovascular Medicine

FEBRUARY 23, 2024

Introduction The presence of non-coronary atherosclerosis (NCA) in patients with coronary artery disease is associated with a poor prognosis. We have studied whether NCA is also a predictor of poorer outcomes in patients undergoing coronary artery bypass grafting (CABG).

Coronary Artery Bypass Graft

Coronary Artery Bypass Graft Atherosclerosis Peripheral Arterial Disease Coronary Artery Disease

Proteogenomic Data Integration Reveals CXCL10 as a Potentially Downstream Causal Mediator for IL-6 Signaling on Atherosclerosis

Circulation

DECEMBER 28, 2023

Using mediation Mendelian randomization, we explored proteomic mediators of the effects of genetically proxied IL-6 signaling on coronary artery disease, large artery atherosclerotic stroke, and peripheral artery disease.

Atherosclerosis

Atherosclerosis Peripheral Arterial Disease Coronary Artery Disease Pharmacology

Achieving SVR Reduces Risk of Cardiovascular Events in Patients with HCV

HCPLive

JANUARY 23, 2024

Results highlight the benefit of achieving sustained virological response with DAAs for decreasing patients’ risk of carotid atherosclerosis and peripheral artery disease, especially among those with severe fibrosis.

Peripheral Arterial Disease

Peripheral Arterial Disease Atherosclerosis

American Heart Month Puts Spotlight on Cardiovascular Disease and Stroke Statistics

DAIC

FEBRUARY 1, 2024

February 1, 2024 — As cardiologists, heart disease patients and the organizations that serve them across the country embark on American Heart Month, DAIC has compiled a snapshot of significant cardiovascular disease (CVD) and stroke statistics, along with a review of the atherosclerosis drug market. per 1,000* - 122.4

Cardiovascular Disease

Cardiovascular Disease Atherosclerosis Peripheral Arterial Disease Stroke

Intervention for critical aortic stenosis in Hutchinson-Gilford progeria syndrome

Frontiers in Cardiovascular Medicine

APRIL 24, 2024

Hutchinson-Gilford Progeria Syndrome (HGPS) is an ultra-rare genetic premature aging disease that is historically fatal in teenage years, secondary to severe accelerated atherosclerosis. years by 4.3 years (30%). Intervention to relieve critical AS has the potential for immediate improvement in healthspan and lifespan.

Stenosis

Stenosis Aortic Peripheral Arterial Disease TAVR

2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association

Circulation

JANUARY 24, 2024

METHODS:The AHA, through its Epidemiology and Prevention Statistics Committee, continuously monitors and evaluates sources of data on heart disease and stroke in the United States and globally to provide the most current information available in the annual Statistical Update with review of published literature through the year before writing.

Heart Disease

Heart Disease Peripheral Arterial Disease Stroke Strokes

HeartFlow Announces Revolutionary Five-Year Data Demonstrating a 63 Percent Mortality Reduction with FFRCT-Guided Care in PAD Patients

DAIC

MAY 8, 2024

1 Atherosclerosis is a systemic disease that affects multiple vascular regions and is particularly severe in PAD patients, where up to 80 percent suffer from concurrent coronary artery disease (CAD), historically linked with a mortality rate exceeding 50 percent within five years. Journal of Vascular Surgery, Mar.

Coronary Artery Disease

Coronary Artery Disease Chest Pain Myocardial Infarction Ischemia

Abstract 114: “Failing” DAPT? Think Again

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Repeat CTA head and neck demonstrated multifocal intracranial atherosclerosis with marked stenosis of the left V4 segment. However, marked stenosis at V2 appeared to be owed to external compression from facet arthrosis rather than atherosclerosis. He also had moderate stenosis of the right V4 segment.

Stenosis

Stenosis Peripheral Arterial Disease Atherosclerosis Pacemaker

Lowering Atherosclerotic Cardiovascular Disease Events by Treating Residual Inflammatory Risk

DAIC

JANUARY 23, 2024

1,6 Until recently atherosclerosis has been thought of as the result of passive lipid accumulation in the vessel wall. However, the development of atherosclerosis is now known to be much more complex, with a key role for immune cells and inflammation in conjunction with hyperlipidemia and elevated LDL levels.7

Cardiovascular Disease

Cardiovascular Disease Heart Attack Heart attacks Coronary Artery Disease

Quantification of Skeletal Muscle Perfusion in Peripheral Artery Disease Using 18F?Sodium Fluoride Positron Emission Tomography Imaging

Journal of the American Heart Association

FEBRUARY 14, 2024

BackgroundPerfusion deficits contribute to symptom severity, morbidity, and death in peripheral artery disease (PAD); however, no standard method for quantifying absolute measures of skeletal muscle perfusion exists.

Peripheral Arterial Disease

Peripheral Arterial Disease Atherosclerosis

Trends in peripheral artery disease and critical limb ischemia hospitalizations among cocaine and methamphetamine users in the United States: a nationwide study

Frontiers in Cardiovascular Medicine

JULY 2, 2024

BackgroundPeripheral artery disease (PAD) is on the rise worldwide, ranking as the third leading cause of atherosclerosis-related morbidity; much less is known about its trends in hospitalizations among methamphetamine and cocaine users.ObjectivesWe aim to evaluate the overall trend in the prevalence of hospital admission for PAD with or without the (..)

Peripheral Arterial Disease

Peripheral Arterial Disease Hospital Ischemia Inpatient

Cardiovascular Update

Challenges and opportunities in the management of type 2 diabetes in patients with lower extremity peripheral artery disease: a tailored diagnosis and treatment review

New Guidelines on Peripheral Artery Disease Issued by American Heart Association, American College of Cardiology and Leading Medical Societies

Scientists find cancer-like features in atherosclerosis, spurring opportunity for new treatment approaches

Non-coronary atherosclerosis: a marker of poor prognosis in patients undergoing coronary artery bypass surgery

Proteogenomic Data Integration Reveals CXCL10 as a Potentially Downstream Causal Mediator for IL-6 Signaling on Atherosclerosis

Achieving SVR Reduces Risk of Cardiovascular Events in Patients with HCV

American Heart Month Puts Spotlight on Cardiovascular Disease and Stroke Statistics

Intervention for critical aortic stenosis in Hutchinson-Gilford progeria syndrome

2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association

HeartFlow Announces Revolutionary Five-Year Data Demonstrating a 63 Percent Mortality Reduction with FFRCT-Guided Care in PAD Patients

Abstract 114: “Failing” DAPT? Think Again

Lowering Atherosclerotic Cardiovascular Disease Events by Treating Residual Inflammatory Risk

Quantification of Skeletal Muscle Perfusion in Peripheral Artery Disease Using 18F?Sodium Fluoride Positron Emission Tomography Imaging

Trends in peripheral artery disease and critical limb ischemia hospitalizations among cocaine and methamphetamine users in the United States: a nationwide study

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