Circulation

NOVEMBER 11, 2024

Background:The current unmet needs for aspirin usage in atherosclerosis lie in its short half-life and narrow indication for anti-platelet effects. Daily aspirin intake is mandatory, and the anti-inflammatory effects of aspirin for atherosclerosis have not successfully translated to clinical practice.

Atherosclerosis 40

Atherosclerosis Diet Circulation Ischemia 40

Frontiers in Cardiovascular Medicine

AUGUST 7, 2024

This article evaluates the utility of S100A8/A9 protein as a biomarker and therapeutic target for diagnosing cardiovascular diseases, considering its structural features, fundamental biological properties, and its multifaceted influence on cardiovascular conditions including atherosclerosis, myocardial infarction, myocardial ischemia/reperfusion injury, (..)

Cardiovascular Disease 52

Cardiovascular Disease Myocardial Infarction Atherosclerosis Biomarkers 52

Frontiers in Cardiovascular Medicine

JANUARY 10, 2024

Coronary heart disease is a narrowing or obstruction of the vascular cavity caused by atherosclerosis of the coronary arteries, which leads to myocardial ischemia and hypoxia. At present, percutaneous coronary intervention (PCI) is an effective treatment for coronary atherosclerotic heart disease.

Heart Disease 59

Heart Disease Stents Stent Atherosclerosis 59

DAIC

MARCH 6, 2024

The CAD Staging System is a noninvasive imaging-based investigational software device that analyzes important and actionable features of coronary atherosclerosis, stenosis and ischemia. Food and Drug Administration ( FDA ) for its Coronary Artery Disease ( CAD ) Staging System.

Heart Disease 105

Heart Disease Heart Attack Heart attacks Technology 105

Dr. Smith's ECG Blog

MARCH 1, 2023

The precordial STD persists in severity from V4-V6, rather than being maximal in V1-V4 (as in posterior OMI), and so the ECG overall best fits the subendocardial ischemia pattern (diffuse supply/demand mismatch). Meyers serves as a reminder of the important clinical entity known as diffuse subendocardial ischemia.

Chest Pain 52

Chest Pain Ischemia Tachycardia Stenosis 52

Hypertension Journal

JANUARY 4, 2024

vascular smooth muscle cell phenotypic switching and migration into the intima contribute to atherosclerosis, while hypercontractility increases systemic vascular resistance and vasospasm that can trigger ischemia.

Blood Pressure 45

Blood Pressure Hypertension Atherosclerosis Ischemia 45

Stroke Journal

FEBRUARY 1, 2024

The cohort was composed of patients with a) TIA mimic presentation (n= 142 TIA mimics: an acute onset of neurological symptoms lasting <24h, that can be explained by some identifiable process other than cerebral ischemia including migraine, seizure, peripheral vestibular disease, brain tumors, syncope, root or peripheral nerve disease, and others); (..)

Atherosclerosis 40

Atherosclerosis Ischemia Risk Factors Hemorrhage 40

Hypertension Journal

OCTOBER 23, 2023

BACKGROUND:Abnormal orthostatic blood pressure (BP) regulation may result in cerebral hypoperfusion and brain ischemia and contribute to dementia. Hypertension, Ahead of Print. It may also manifest as early symptoms of the neurodegenerative process associated with dementia.

Dementia 40

Dementia Blood Pressure Atherosclerosis Ischemia 40

Stroke Journal

JANUARY 30, 2025

Introduction:Elevated Low-Density-Lipoprotein Cholesterol (LDL-C) blood levels are a risk factor for atherosclerosis. For this study, acute symptomatic was defined as hemispheric ischemic stroke or retinal ischemia ipsilateral to the carotid stenosis, with symptom onset within 24 hours of admission. were asymptomatic and 40.2%

Stenosis 40

Stenosis Atherosclerosis Cholesterol Ischemia 40

Dr. Smith's ECG Blog

NOVEMBER 15, 2023

This suggests further severe ischemia. See "Mechanisms of acute coronary syndromes related to atherosclerosis".) There is 1 mm of ST segment elevation in lead aVR — which in the context of ST segment flattening in most other leads, suggests that there may be a component of subendocardial ischemia from underlying coronary disease.

Coronary Angiogram 109

Coronary Angiogram Plaque Thrombosis STEMI 109

All About Cardiovascular System and Disorders

MAY 19, 2024

Absence of brachiocephalic artery occlusion which will increase the risk of intraprocedural cerebral ischemia 3. Contralateral or left atherosclerosis in the carotid artery with significant stenosis or occlusion was a contraindication for this approach. No calcifications in the artery causing vascular stenosis.

Aortic valve 40

Aortic valve Aortic TAVR Open-Heart Surgery 40

Dr. Smith's ECG Blog

JANUARY 3, 2022

2] Here there is no posterior ST elevation, but the anterior ST depression is also less—so it is dynamic, confirming acute ischemia. The absence of STE in V7-V9 is often due to resolution of ischemia, as seen by resolution of ST depression in V7-V9. 4] CT revealed no dissection but extensive coronary atherosclerosis.

STEMI 52

STEMI Myocardial Infarction Chest Pain Ischemia 52

Dr. Smith's ECG Blog

JULY 31, 2013

T-wave inversion in V2 is inconsistent with early repol, and is typical of posterior ischemia. In addition, there is ST depression, diagnostic of ischemia, in V3-V6. Nevertheless, even young people have atherosclerosis and plaque rupture. T-waves in inferior leads are hyperacute, out of proportion to those in early repol 5.

Chest Pain 52

Chest Pain Aneurysm STEMI Ischemia 52

Dr. Smith's ECG Blog

OCTOBER 24, 2019

This strongly suggests reperfusing RCA ischemia. Troponins, echocardiogram An echocardiogram showed inferobasilar hypokinesis, further supporting a diagnosis of regional ischemia , likely of the area supplied by the RCA. There is also a Q-wave in III. There is also subtle STD in V3-V5. The initial troponin I was elevated at 0.75

Chest Pain 52

Chest Pain SCAD STEMI Cardiogenic Shock 52

Dr. Smith's ECG Blog

APRIL 29, 2020

Angiogram --Minimal coronary atherosclerosis --No obstructive epicardial coronary artery disease or evidence of plaque rupture noted to explain prolonged QT or ventricular fibrillation cardiacarrest, suspect nonischemic mechanism Echo The estimated left ventricular ejection fraction is 45 %. Acute ischemia? Use of QT-prolonging drugs?

Cardiac Arrest 52

Cardiac Arrest Defibrillator Ischemia Tachycardia 52

Dr. Smith's ECG Blog

NOVEMBER 30, 2022

See "Mechanisms of acute coronary syndromes related to atherosclerosis".) 1-4 Surprisingly, serial angiographic studies have revealed that the plaque at the site of the culprit lesion of a future acute myocardial infarction often does not cause stenosis that, as seen on the antecedent angiogram, is sufficiently severe to limit flow.

Plaque 52

Plaque Chest Pain Thrombosis Stenosis 52

Frontiers in Cardiovascular Medicine

MARCH 18, 2025

Finally, we also emphasize the preclinical/clinical translational significance of neutrophil-targeted strategies.

Cardiovascular Disease 52

Cardiovascular Disease Atrial Fibrillation Atherosclerosis Ischemia 52

DAIC

MAY 8, 2024

1 Atherosclerosis is a systemic disease that affects multiple vascular regions and is particularly severe in PAD patients, where up to 80 percent suffer from concurrent coronary artery disease (CAD), historically linked with a mortality rate exceeding 50 percent within five years. Journal of Vascular Surgery, Mar. 2024, [link].

Coronary Artery Disease 111

Coronary Artery Disease Chest Pain Ischemia Myocardial Infarction 111

DAIC

JULY 18, 2024

Cardiovascular disease is the most common cause of death and disability globally, largely driven by myocardial infarction and ischemic stroke caused by atherosclerosis (plaque build-up in the arteries).

Plaque 105

Plaque Heart Attack Heart attacks Cardiovascular Disease 105

Frontiers in Cardiovascular Medicine

JULY 2, 2024

BackgroundPeripheral artery disease (PAD) is on the rise worldwide, ranking as the third leading cause of atherosclerosis-related morbidity; much less is known about its trends in hospitalizations among methamphetamine and cocaine users.ObjectivesWe aim to evaluate the overall trend in the prevalence of hospital admission for PAD with or without the (..)

Peripheral Arterial Disease 52

Peripheral Arterial Disease Hospital Ischemia Inpatient 52

DAIC

JANUARY 23, 2024

1,6 Until recently atherosclerosis has been thought of as the result of passive lipid accumulation in the vessel wall. However, the development of atherosclerosis is now known to be much more complex, with a key role for immune cells and inflammation in conjunction with hyperlipidemia and elevated LDL levels.7 12 Colchicine, 0.5

Cardiovascular Disease 111

Cardiovascular Disease Heart Attack Heart attacks Coronary Artery Disease 111

DAIC

MAY 16, 2024

PAD is a serious, progressive cardiovascular disease primarily caused by a buildup of fatty plaque in the blood vessels, or atherosclerosis. If left untreated, PAD may progress to severe forms known as chronic limb-threatening ischemia (CLTI) and acute limb ischemia (ALI). and Global Data From the American Heart Association.

Peripheral Arterial Disease 105

Peripheral Arterial Disease Exercise Ischemia Quality of Life 105

EMS 12-Lead

APRIL 21, 2022

There is appreciable STE aVR with near-global STD that appropriately maximizes in Leads II and V5, and thus suggesting a circumstance of generic, diffusely populated, circumferential subendocardial ischemia versus occlusive coronary thrombus. [1] There is evolution from Wellens Pattern A to Pattern B, now inclusive of V6.

Ischemia 52

Ischemia Myocardial Infarction Blog Coronary Angiogram 52

Frontiers in Cardiovascular Medicine

JUNE 26, 2024

ACS may arise from the disruption of an atherosclerotic plaque, ultimately leading to acute ischemia and myocardial infarction. Acute Coronary Syndrome (ACS) significantly contributes to cardiovascular death worldwide.

Plaque 52

Plaque Myocardial Infarction Atherosclerosis Ischemia 52

Heart 2023 Conference

APRIL 20, 2022

Source: JAMA Cardiology) Patients with afib who survived an intracerebral haemorrhage had a very significant risk of cerebrovascular ischemia episodes and death in the following year, according to registry data.

Pulmonary 52

Pulmonary Hypertension AFIB COVID-19 52

Dr. Paddy Barrett

AUGUST 1, 2023

A CT CAC scan can only identify if there is calcified atherosclerosis, where it is and to what extent. A CT CAC scan of 0 indicates no significant amount of calcified atherosclerosis. It does not imply that there is NO advanced atherosclerosis. 5 ISCHEMIA Research Group. And it matters. Eur Heart J. N Engl J Med.

Coronary Angiogram 52

Coronary Angiogram Plaque Coronary Artery Disease Chest Pain 52

Wellnest

DECEMBER 21, 2022

Poor blood supply Ischemia, or inadequate blood supply to the heart, is an abnormality that can be detected in an ECG test. This condition is also called atherosclerosis. If the vital organs do not get their blood supply back quickly, it can lead to death. It is a breakdown of the heart's electrical system.

Cardiac Arrest 52

Cardiac Arrest Heart Attack Heart attacks Atrial Fibrillation 52

Circulation

NOVEMBER 11, 2024

Background:The presence of carotid plaque (CP) may serve as an indicator of panvascular atherosclerosis. We computed a Vascular Disease (VasD) score, integrating the presence of carotid plaque (CP) on carotid ultrasound, known coronary artery disease (CAD), and myocardial ischemia (MyI). Subsequently, patients were followed for 5.5

Exercise 40

Exercise Coronary Artery Disease Ultrasound Plaque 40

Journal of the American Heart Association

FEBRUARY 27, 2024

BackgroundWomen with chronic coronary disease are generally older than men and have more comorbidities but less atherosclerosis. Despite lower risk factor goal attainment, women with chronic coronary disease experienced similar risk‐adjusted outcomes to men in the ISCHEMIA trial.RegistrationURL:[link] Unique identifier: NCT01471522.

Ischemia 45

Ischemia Coronary Artery Disease Myocardial Infarction Outcomes 45

DAIC

FEBRUARY 7, 2024

His main career interests are in improving treatments for patients with intracranial arterial atherosclerosis and helping to mentor the next generation of clinical and translational scientists. The Ralph L.

Stroke 105

Stroke Strokes Research Health Disparities 105