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While advances in treatment have reduced mortality in some regions, the atherosclerosis prevention remains challenging. This shift results from an epidemiologic transition: as infectious diseases decline, chronic conditions like atherosclerosis dominate.
This study aimed to evaluate the riskfactors associated with LV mass and subclinical coronary atherosclerosis, in an Asian population free of baseline cardiovascular disease. Individuals were stratified based on LVMI and the presence of CAC, and intergroup differences in riskfactors were analysed.
Introduction:Prior studies have shown the association between oral infection, white matter hyperintensity (WMH), a marker of cerebral small vessel disease (CSVD), and asymptomatic intracranial atherosclerosis (ICAS). However, the impact of preventative oral behavior such as dental flossing is unknown. The log WMH volume was higher (9.50.85
High blood pressure, also known as hypertension, is a common condition that affects millions of people worldwide. Often referred to as the silent killer, hypertension can quietly damage your heart and other vital organs over time. Hypertension is diagnosed when blood pressure consistently reads 130/80 mm Hg or higher.
The BACKBEAT pivotal study will evaluate the efficacy and safety of atrioventricular interval modulation (“AVIM”) therapy (also known as BackBeat CNT), for the treatment of pacemaker-indicated patients with uncontrolled hypertension despite the use of antihypertensive medications. Orchestra BioMed and Medtronic, Inc. Kowal, M.D., and Europe.
Hypertension, Ahead of Print. BACKGROUND:Orthostatic hypertension is an emerging riskfactor for adverse events. These differences in CVD risk raise important concerns about combining systolic orthostatic increases and standing SBP 140 mm Hg in a consensus definition for orthostatic hypertension.
The EAS 2024 Congress (May 26-29, 2024) has concluded, providing critical insights into atherosclerosis and related vascular disease. This has major potential to refine risk stratification and enhance patient management. Here are some notable highlights: Prof. In contrast, Dr. Michael D.
February 1, 2024 — As cardiologists, heart disease patients and the organizations that serve them across the country embark on American Heart Month, DAIC has compiled a snapshot of significant cardiovascular disease (CVD) and stroke statistics, along with a review of the atherosclerosis drug market. per 1,000* - 122.4
Here’s what you can expect at the biggest conference in cardiorenal metabolic health, the 19th Annual Cardiometabolic Congress (CMHC), DECODING THE CONSTELLATION of Cardiometabolic Health and RiskFactors. Michos, MD, MHS, FACC, FAHA, FASE, FASPC ; famed hypertension expert Keith C.
Heart disease remains one of the leading causes of death worldwide, often attributed to a mix of lifestyle choices, environmental factors, and genetic predispositions. This blog explores how genetics influence heart health and whether mitigating these inherited risks is possible. Can You Prevent Heart Disease if Its in Your Genes?
A 63 year old man with a history of hypertension, hyperlipidemia, prediabetes, and a family history of CAD developed chest pain, shortness of breath, and diaphoresis after consuming a large meal at noon. He called EMS, who arrived on scene about two hours after the onset of pain to find him hypertensive at 220 systolic.
Any atherosclerotic plaque is bad, and its presence portends a worse prognosis if modifiable riskfactors like hypertension and smoking are not addressed.
Introduction:Excessive dietary salt intake is a recognized ASCVD riskfactor, and causes approximately 1.89 There is also an ongoing discussion whether dietary salt might be associated with the direct ASCVD risk. Circulation, Volume 150, Issue Suppl_1 , Page A4145926-A4145926, November 12, 2024. million deaths annually.
The prevalence of HF riskfactors was high: hypertension, 61.9%; former or current smoking, 53.7%; obesity 34.8%; diabetes; 24.7%; and chronic kidney disease; 22%. Results:Median age was 73 (25th–75th percentile 67–81) years, 53.2% were female, 25.6% were Black, 12.8% were Chinese, and 40.0% were White. were female, 25.6%
The American Heart Association draws attention to nonalcoholic fatty liver disease, which affects about one in four adults and is a riskfactor for atherosclerotic cardiovascular disease. JACC: Asia) Lexaria Bioscience has announced that a CBD product beats a placebo in simulating acute pulmonary hypertension.
At the patient level, those with reduced CFR showed a significantly higher prevalence of diffused atherosclerosis (41% vs. 23%; P < 0.001) and higher FAI (−75.5 HU In the patient-level analysis, obstructive CAD, diffused atherosclerosis, and FAI were independently linked with CFR. Results We detected a decrease in CFR (<2.5)
Urine output gradually returned after 3 weeks, and serum creatinine level was normalized after 2 months.ConclusionsTransplant recipients commonly have atherosclerosis and hypertension, which are riskfactors for arterial dissection.
Those having these mutations have increased vascular inflammation before it progresses to malignancies and double the risk of ischemic stroke. It has been mentioned that risk due to clonal hematopoiesis is equal in magnitude to conventional riskfactors like smoking, hypertension, dyslipidemia and diabetes.
Background:Migraine with aura is a riskfactor for ischemic stroke. We refined the migraine with aura risk score (MARS) to create the migraine associated risk of stroke score (MARS Plus) making it applicable to migraine with and without aura. Stroke, Volume 55, Issue Suppl_1 , Page AWP241-AWP241, February 1, 2024.
While traditional vascular riskfactors (eg, hypertension, dyslipidemia, tobacco use) account for 20% of the explained variance in carotid atherosclerosis, they remain a prominent focus for primary and secondary ischemic stroke prevention strategies. Stroke: Vascular and Interventional Neurology, Ahead of Print.
While this response is adaptive in the short term, chronic stress keeps your blood pressure elevated for extended periods, increasing your risk of hypertension (high blood pressure) and its associated complications, such as heart disease and stroke.
Small vessel disease (SVD), as measured by cerebral microbleeds (CMBs) and white matter hyperintensities (WMH), has been associated with riskfactors and might be a predictor of incident ICH. CMBs result from irregularities in brain vessel structure due to chronic hypertension and cerebral amyloid angiopathy.
White matter hyperintensities (WMH) and cerebral microbleeds (CMB) are manifestations of CSVD.Methods:Using the AtherosclerosisRisk in Communities (ARIC) database, we extracted data from 1112 participants assessed for dental caries and vascular riskfactors. Of those, 203 (18.3%) had caries and 909 (81.7%) did not.
Riskfactors for cardiovascular disease Understanding the riskfactors for cardiovascular disease is crucial for maintaining optimal cardiovascular health. While some riskfactors, such as age and family history, cannot be changed, others are within our control.
Education and Empowerment Educating patients about their condition and the importance of managing cardiometabolic riskfactors can empower them to take control of their health, improve healthcare outcomes, and reduce clinician burnout. This ensures clear communication and identifies areas that need further explanation.
The HR was nonsignificant after adjustment for age, gender, race, hypertension, diabetes, hypercholesterolemia and smoking status, adjusted HR 1.33 Conclusion:We report a possible association between migraine sufferers on SSRIs and risk for incident stroke. with a 95% CI of 0.89-1.99.Conclusion:We
CMBs in lobar regions suggest cerebral amyloid angiopathy (CAA), which is sometimes accompanied by superficial siderosis (SS), while subcortical CMBs indicate hypertensive origins. Model covariates included demographics, vascular riskfactors, and imaging markers of small vessel disease.Results:Among 1609 participants, 364 had CMBs (Table 1).
Our case describes a patient with right extracranial internal carotid artery (ICA) thrombus secondary to later‐diagnosed CaW on close follow‐up imaging.MethodsWe report a 55‐year‐old African American man with history of hypertension, type 2 diabetes mellitus and hyperlipidemia presented with acute onset slurred speech and left facial droop (FP).
Repeat CTA head and neck demonstrated multifocal intracranial atherosclerosis with marked stenosis of the left V4 segment. However, marked stenosis at V2 appeared to be owed to external compression from facet arthrosis rather than atherosclerosis. Timely diagnosis is imperative, as decompressive surgery can be curative.
Patients with angiographically confirmed MMD diagnosis with at least 6 months follow-up and completion of revascularization surgery were included; patients with intracranial atherosclerosis, intracranial dissection, vasculitis, and undefined inflammatory processes were excluded. at 1 year, 82.4% at 3 years, 68.8% at 5 years, and 28.3%
He had no further riskfactors for atherosclerosis besides hypertension. I was on scene at his working place (in Germany physicians are on the Emergency vehicles). Surprisingly enough he had undertaken a tour on the bike just two days ago without any complaints." "He
APOB The fundamental basis of coronary artery disease is when a cholesterol particle is retained in the artery wall, and an inflammatory cascade occurs, resulting in the formation of atherosclerosis. The greater the number of particles, the higher the risk. The number of APOB particles is the best measure of that risk.
Background:Vascular riskfactors, particularly in midlife, are associated with an increased risk of dementia, and smoking has been inversely associated with Parkinson's disease (PD) risk, but the role of these factors in PD-dementia (PDD) is less clear. yo, 94 devleoped PDD at a mean age of 79.2
Objective:Late-life vascular health and cerebrovascular disease have been identified as potential riskfactors for late-life depression (LLD). To assess cumulative vascular risk burden, the number of VRFs were counted and categorized as 0, 1, 2, or 3. 1.98), hypertension (OR: 1.29, 95% CI: 1.02-1.61), At midlife, 20.2%
The aim of this study was to identify different patterns of CAC change and evaluate the associations with different cardiovascular outcomes.MethodsData from the Multi-Ethnic Study of Atherosclerosis study were analyzed. Participants with at least three CT measurements were included. The main study outcome is hard cardiovascular disease (CVD).
Background:Trimethylamine N-oxide (TMAO), a gut microbiome-derived metabolite trimethylamine-containing nutrients, is mechanistically linked to atherosclerosis progression and platelet aggregation, leading to cardiovascular disease. Stroke, Volume 56, Issue Suppl_1 , Page AWP336-AWP336, February 1, 2025. p< 0.05).
Cox regression was used to estimate the hazard ratio (HR) for incident stroke per doubling of EIC levels, and p-values were FDR corrected. Results:Among the 9,444 participants included, the mean age was 57 (5.7 SD), and 43.2%
Introduction:It is known that past the age of 35, the prevalence of large artery atherosclerosis (LAA) related strokes increases with a cardiovascular riskfactor (CVRF) profile beginning to resemble that of elderly patients. A significantly larger proportion of patients with LAA had baseline CVRFs including hypertension (80.0%
We aimed to evaluate the association between carotid artery tortuosity and the incidence of ischemic stroke.Methods:We analyzed 3D contrast-enhanced MRA datasets from 2,066 participants enrolled in the AtherosclerosisRisk in Communities (ARIC) Carotid MRI study. fold increased risk of ischemic stroke (95% CI, 1.08-5.61)
Four years on, it is still among the most extensive studies measuring the progression of cardiovascular diseases among initially healthy individuals and associating the costs of treating CVD with different riskfactors. Like age, diabetes, dyslipidemia, and hypertension are also widely accepted as cardiovascular disease factors.
Introduction:Apolipoprotein E4 (ApoE4) allele is linked to increased LDL-Cholesterol, one of the main riskfactors for intracranial large artery stenosis (ICAS). While the link between ApoE4 and extracranial atherosclerosis and vascular riskfactors is established, the association of these vascular factors with ICAS is unknown.
Objective:High calcium (Ca), low phosphate(P), and Ca-P product (CPP) levels are associated with cardiovascular disease and coronary artery atherosclerosis in patients with chronic kidney disease. However, whether this relationship persists in individuals with carotid artery atherosclerosis of acute ischemic stroke is unknown.
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