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Climbing more than five flights of stairs every day can reduce the risk of atherosclerotic cardiovascular disease by over 20% according to a study using data from the UK Biobank, published in the journal Atherosclerosis [1]. Similar results were noted for both coronary artery disease and ischemic stroke. Median follow up period was 12.5
About a fifth of all ischemic strokes are attributed to embolization of ruptured atherosclerotic plaque from carotid arterial stenosis. But it has been difficult to predict which person with asymptomatic carotid artery stenosis is likely to progress to symptomatic carotid disease and stroke.
There were no significant effects on fatal or nonfatal stroke, death from cardiovascular causes and death from any cause. Liver-specific ATP-citrate lyase inhibition by bempedoic acid decreases LDL-C and attenuates atherosclerosis. 6992 patients were assigned to bempedoic acid and 6978 to placebo group. Nat Commun. 2016 Nov 28;7:13457.
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