Stroke Journal

FEBRUARY 1, 2024

Background:Most ischemic strokes are caused by atherosclerosis. Apolipoprotein E (ApoE) regulates lipid metabolism, and its deficiency is associated with dyslipidemia and atherosclerosis. Poor dietary habits promote the onset of atherosclerosis. Stroke, Volume 55, Issue Suppl_1 , Page ATP300-ATP300, February 1, 2024.

Atherosclerosis 40

Atherosclerosis Risk Factors Diet Plaque 40

Circulation

NOVEMBER 11, 2024

CCR5, a chemokine receptor, has been associated with both immunosuppressive and inflammatory phenotypes, however, the possible role of CCR5 pertaining to MDSCs in the development of atherosclerosis has not been elucidated yet. Possibly this dysfunctionality contributes to the development and progression of CVD including atherosclerosis.

Atherosclerosis 40

Atherosclerosis Plaque Coronary Artery Disease Diet 40

Circulation

NOVEMBER 11, 2024

Background:The current unmet needs for aspirin usage in atherosclerosis lie in its short half-life and narrow indication for anti-platelet effects. Daily aspirin intake is mandatory, and the anti-inflammatory effects of aspirin for atherosclerosis have not successfully translated to clinical practice.

Atherosclerosis 40

Atherosclerosis Diet Circulation Ischemia 40

Frontiers in Cardiovascular Medicine

AUGUST 2, 2024

Dysfunctional WAT drive chronic inflammation and facilitate atherosclerosis. Here, we combined the single-cell RNA sequencing technique with cell metabolic and functional assays on major WAT ATM subpopulations using a diet-induced atherosclerosis mouse model (Apoe-null). Interestingly, LAM increased 8.4-fold

Diet 52

Diet Atherosclerosis Obesity 52

Dr. Paddy Barrett

DECEMBER 19, 2023

Coronary Atherosclerosis There are multiple ways of describing coronary plaque: The degree of obstruction The composition of the plaque The thickness of the plaque wall (Cap) that separates the plaque from the inside of the blood vessel. Good nutrition (Not just a DASH diet, I suspect) changes plaque composition to safer, more stable plaque.

Coronary Artery Disease 106

Coronary Artery Disease Plaque Exercise Heart Attack 106

DAIC

FEBRUARY 3, 2025

More than 90% of the Lp(a) level is influenced by variations in the genes controlling the Lp(a) particle production, 2 in which lifestyle interventions such as diet and exercise have no significant impact. 2022 Aug, 80 (9) 934946 Kronenberg F.

Cardiovascular Disease 52

Cardiovascular Disease Aortic valve Biomarkers Innovation 52

Dr. Paddy Barrett

JANUARY 24, 2025

I am a fan of using low-carb diets for both weight loss and improving metabolic health. Low-carb diets have consistently shown benefits in improving these parameters 1. In the early 1970’s a group of 106 severely obese patients were put on a diet that resulted in an average weight loss of 63 Kg (139 lbs) over about one year 2.

Diet 52

Diet Obesity Diabetes Cholesterol 52

Stroke Journal

JANUARY 30, 2025

Background:PCSK9, a key regulator of cholesterol metabolism, has been implicated in atherosclerosis. PCSK9 overexpression was induced via AAV injection, and mice were subjected to either a normal diet or HFD for 4 months. However, its potential role in vascular cognitive impairment and dementia (VCID) remains elusive.

Diet 40

Diet Dementia Atherosclerosis Cholesterol 40

GEMMS

NOVEMBER 22, 2023

Regular exercise, a balanced diet, and lifestyle choices such as not smoking and managing stress are all crucial for achieving and maintaining optimal cardiovascular health. The role of diet in cardiovascular health Diet plays a significant role in maintaining cardiovascular health.

Blood Pressure 52

Blood Pressure Cholesterol Diet Exercise 52

Circulation

NOVEMBER 11, 2024

a unique approach, we crossed DS model mice withApoE-null mice and fed them a high-fat diet (HFD) for 12 weeks to survey the effects of DS-related genes on atherosclerosis. The results were striking, with HFD-mediated increased LDL and triglyceride levels inApoE-null mice significantly reduced in the combined DS plusApoE-null mice.

Atherosclerosis 40

Atherosclerosis Diet Innovation Research 40

MIBHS

AUGUST 15, 2024

Blood Vessels: Chronic stress can impair the function of the endothelium—the lining of blood vessels—potentially leading to atherosclerosis, a precursor to heart disease. Balanced Diet: A healthy diet can support overall health and help manage stress. Adequate Sleep: Good sleep hygiene can help regulate cortisol rhythms.

Blood Pressure 52

Blood Pressure Cholesterol Heart Disease Diet 52

AMS Cardiology

JANUARY 21, 2023

Low-density lipoprotein (LDL) or “bad cholesterol” can create plaque in your arteries, putting you at risk for health complications like atherosclerosis, heart disease and vascular issues. Reduce saturated fats and eliminate trans fats from your diet. You should also eliminate all trans fat from your diet.

Cholesterol 40

Cholesterol Diet Blood Pressure Heart Attack 40

Cardiometabolic Health Congress

AUGUST 23, 2024

Dyslipidemia, characterized by an imbalance in lipids such as cholesterol, LDL-C, triglycerides, and HDL, can result from various factors, including diet, tobacco and alcohol use, a sedentary lifestyle, or genetic conditions like familial hypercholesterolemia.

Dementia 52

Dementia Cholesterol Risk Factors CME 52

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

A 69‐year‐old woman with a history of lung cancer, hypertension, chronic tobacco use, atherosclerosis, and known calcified plaque at the left carotid bifurcation on dual antiplatelet therapy presented with acute onset of expressive aphasia and right hemiparesis due to acute left CCAO. Post‐operatively, he had evacuation of neck hematoma.

Outcomes 40

Outcomes Chest Pain Coronary Artery Disease Aortic 40

Cardiometabolic Health Congress

JANUARY 15, 2025

While advances in treatment have reduced mortality in some regions, the atherosclerosis prevention remains challenging. This shift results from an epidemiologic transition: as infectious diseases decline, chronic conditions like atherosclerosis dominate.

Atherosclerosis 59

Atherosclerosis Plaque Myocardial Infarction Risk Factors 59

MIBHS

FEBRUARY 28, 2025

While much attention is given to modifiable risk factors such as diet, exercise, and smoking, the role of genetics in heart disease is equally critical yet less understood by the general public. Inflammation: Genetic variations can make some people more prone to chronic inflammation, which contributes to the development of atherosclerosis.

Genetic predisposition 52

Genetic predisposition Heart Disease Cholesterol Blood Pressure 52

Physiologically Speaking

FEBRUARY 23, 2024

High-protein diets are often advocated for building muscle, losing weight, and optimizing body composition. Eating this amount of protein means your diet will comprise about 11% of calories from protein, leaving fat and carbs to fill the gaps. In simpler terms: In mice, a high-protein (and hence high-amino-acid) diet activates mTORC1.

Physiology 111

Physiology Atherosclerosis Diet Cardiovascular Disease 111

Frontiers in Cardiovascular Medicine

FEBRUARY 16, 2024

Introduction Atherosclerosis is a chronic inflammatory disease caused by the deposition of lipids within the artery wall. Here, we sought to investigate the role of autophagy activation during atherosclerosis regression.

Atherosclerosis 64

Atherosclerosis Plaque Diet Cholesterol 64

Dr. Paddy Barrett

JANUARY 23, 2024

Share While the average Western male and female will develop advanced coronary artery disease by age 55 and 66, respectively, 85% of the Tsimane tribe population over 40 had no evidence of advanced atherosclerosis 2. Coronary atherosclerosis, as evidenced by an abnormal CAC score, is a measure of advanced plaque. In my view.

Heart Disease 106

Heart Disease Blood Pressure Dementia Atherosclerosis 106

Circulation

DECEMBER 15, 2023

In a conventional Western diet model for 2 months, HEG1iECKOmice also showed an exacerbated atherosclerosis development in the arterial tree in both sexes and the aortic sinus in males but not in females. Circulation, Ahead of Print.

Atherosclerosis 45

Atherosclerosis Diet Aortic Plaque 45

Circulation

NOVEMBER 11, 2024

More than 1/3 of the respondents correctly indicated the permissible amount of salt in the diet recommended by WHO; even larger percentage (86.3%) correctly indicated that limiting salt intake in the diet applies to both healthy and sick people. to even 53%.

Atherosclerosis 40

Atherosclerosis Diet Lipid disorders Risk Factors 40

Cardiometabolic Health Congress

AUGUST 8, 2024

A meta-analysis published in the Journal of Consulting and Clinical Psychology found that motivational interviewing effectively promoted behavior change across various health domains, including diet and exercise. Key contributions: Advanced cardiac imaging (e.g.,

Education 59

Education Cardiovascular Disease Diabetes Kidney Disease 59

Physiologically Speaking

APRIL 12, 2024

ICYMI On Wednesday, I published a post about the recent evidence on high-volume exercise and atherosclerosis in athletes. Not surprising given that diet and physical activity outside of the intervention didn’t change. Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication.

Exercise 98

Exercise Physiology Blood Pressure Public Health 98

DAIC

MAY 16, 2024

PAD is a serious, progressive cardiovascular disease primarily caused by a buildup of fatty plaque in the blood vessels, or atherosclerosis. This plaque narrows the blood vessels and reduces blood flow to the legs and feet, which may significantly impair physical function, walking performance and quality of life.

Peripheral Arterial Disease 105

Peripheral Arterial Disease Exercise Ischemia Quality of Life 105

The British Journal of Cardiology

APRIL 16, 2024

1 In addition to genetic and behavioural risk factors (unhealthy diet, physical inactivity, and tobacco and alcohol abuse), inhaling airborne pollutants, such as fine particulate matter (<2.5 Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of death worldwide, causing around 17.9

Cardiovascular Disease 40

Cardiovascular Disease Public Health Diet Risk Factors 40

Dr. S. Venkatesan MD

JANUARY 8, 2024

LDL is obviously a target against atherosclerosis. While, the relationship between LDL and atherosclerosis is so intimate, funnily we have heaps of data that show South Asian population with tons & tons of plaque with normal LDL. Preamble 15 % of body weight is fat.

Cholesterol 52

Cholesterol Atherosclerosis Plaque Physiology 52

Physiologically Speaking

APRIL 24, 2024

The amount of calcium in the blood vessels (known as arterial calcification), a marker of subclinical atherosclerosis, is higher in people with a short sleep duration. 14 One study of over 1,900 men found evidence that very short sleep duration predicts a higher burden of atherosclerosis in their coronary and femoral arteries.

Blood Pressure 52

Blood Pressure Blood Clot COVID-19 Cardiovascular Disease 52

Physiologically Speaking

DECEMBER 17, 2024

Coronary artery calcium (CAC) is a measure of atherosclerosis and a strong predictor of cardiovascular disease. The Latest Evidence on Atherosclerosis in Athletes The risk factor component is yet unexplored—how do risk factors other than training contribute to elevated CAC in endurance athletes?

Risk Factors 105

Risk Factors Genetic predisposition Plaque Exercise 105

Frontiers in Cardiovascular Medicine

DECEMBER 20, 2024

Cholesterol aggregation in dendritic cells (DCs) triggers an inflammatory response and accelerates the development of atherosclerosis (AS). Resveratrol (RES), a natural compound with anti-inflammatory and cholesterol metabolism regulatory properties, has been shown to influence the maturation and inflammatory functions of DCs.

Cholesterol 52

Cholesterol Diet Atherosclerosis Research 52