This site uses cookies to improve your experience. To help us insure we adhere to various privacy regulations, please select your country/region of residence. If you do not select a country, we will assume you are from the United States. Select your Cookie Settings or view our Privacy Policy and Terms of Use.
Cookie Settings
Cookies and similar technologies are used on this website for proper function of the website, for tracking performance analytics and for marketing purposes. We and some of our third-party providers may use cookie data for various purposes. Please review the cookie settings below and choose your preference.
Used for the proper function of the website
Used for monitoring website traffic and interactions
Cookie Settings
Cookies and similar technologies are used on this website for proper function of the website, for tracking performance analytics and for marketing purposes. We and some of our third-party providers may use cookie data for various purposes. Please review the cookie settings below and choose your preference.
Strictly Necessary: Used for the proper function of the website
Performance/Analytics: Used for monitoring website traffic and interactions
While advances in treatment have reduced mortality in some regions, the atherosclerosis prevention remains challenging. This shift results from an epidemiologic transition: as infectious diseases decline, chronic conditions like atherosclerosis dominate.
Introduction:Prior studies have shown the association between oral infection, white matter hyperintensity (WMH), a marker of cerebral small vessel disease (CSVD), and asymptomatic intracranial atherosclerosis (ICAS). However, the impact of preventative oral behavior such as dental flossing is unknown. The log WMH volume was higher (9.50.85
The BACKBEAT pivotal study will evaluate the efficacy and safety of atrioventricular interval modulation (“AVIM”) therapy (also known as BackBeat CNT), for the treatment of pacemaker-indicated patients with uncontrolled hypertension despite the use of antihypertensive medications. Orchestra BioMed and Medtronic, Inc. Kowal, M.D., and Europe.
February 1, 2024 — As cardiologists, heart disease patients and the organizations that serve them across the country embark on American Heart Month, DAIC has compiled a snapshot of significant cardiovascular disease (CVD) and stroke statistics, along with a review of the atherosclerosis drug market. million have diagnosed diabetes; and 9.7
The EAS 2024 Congress (May 26-29, 2024) has concluded, providing critical insights into atherosclerosis and related vascular disease. Shapiro (United States of America) focused on preventing atherosclerosis over myocardial infarction, suggesting that CAC’s late-stage detection does not fit classic definitions of primary prevention.
Hypertension, Ahead of Print. ETs were shown to play important roles among others, in systemic hypertension, particularly when resistant or difficult to control, and in pulmonary hypertension, atherosclerosis, cardiac hypertrophy, subarachnoid hemorrhage, chronic kidney disease, diabetic cardiovascular disease, scleroderma, some cancers, etc.
Practical, Future-Focused Education Cardiorenal and metabolic diseases, fueled by poor lifestyle choices and health conditions, lead to type 2 diabetes, cardiovascular disease, and chronic kidney disease. Michos, MD, MHS, FACC, FAHA, FASE, FASPC ; famed hypertension expert Keith C.
Don’t worry—you can still access the 19th Annual CMHC sessions through our On-Demand platform, which offers 14 CME credits across four comprehensive tracks: Cardiorenal Health: Stay up-to-date with the latest on therapies for resistant hypertension, chronic kidney disease markers, and cardiac risk assessment tools.
One of the assessments for coronary atherosclerosis during cardiac computed tomography (CT) is coronary artery calcium (CAC) scoring. We found that a history of hypertension and diabetes are independent determinants of having a high-risk CAC score. This study involved a total of 1,129 female patients from a single centre.
Carotid atherosclerosis (CAS) is a critical precursor to atherosclerotic cardiovascular disease and is closely associated with the development and progression of conditions such as stroke and poor prognosis. Stroke, Volume 56, Issue Suppl_1 , Page ATP288-ATP288, February 1, 2025. 2021-KY-1289-001).Results:Among respectively.
Excess salt in the diet was indicated as a recognized risk factor in the case of hypertension 82.4%, atrial fibrillation 28.8%, obesity 36.4%, type 2 diabetes 20.4%, lipid disorders 18.5%, heart failure 59.1%, stroke 56.9%, and atherosclerosis 42.2%. to even 53%.
At the patient level, those with reduced CFR showed a significantly higher prevalence of diffused atherosclerosis (41% vs. 23%; P < 0.001) and higher FAI (−75.5 HU In the patient-level analysis, obstructive CAD, diffused atherosclerosis, and FAI were independently linked with CFR. Results We detected a decrease in CFR (<2.5)
Inflammation: Genetic variations can make some people more prone to chronic inflammation, which contributes to the development of atherosclerosis. Maintain a Healthy Weight: Obesity amplifies the effects of genetic predispositions by contributing to high cholesterol, hypertension, and diabetes.
The prevalence of HF risk factors was high: hypertension, 61.9%; former or current smoking, 53.7%; obesity 34.8%; diabetes; 24.7%; and chronic kidney disease; 22%. Results:Median age was 73 (25th–75th percentile 67–81) years, 53.2% were female, 25.6% were Black, 12.8% were Chinese, and 40.0% were White.
Keynote speaker and atherosclerosis expert Peter Libby, MD , captivated the audience with an update on his research into inflammation and atherosclerosis. He discussed therapeutic options not only for treating atherosclerosis but also for preventing cardiovascular disease.
Background:Ischemic stroke can arise from various etiologies, such as cardioembolism, atherosclerosis, small vessel disease or cryptogenic. were women, 87% had hypertension, 48.1% had diabetes mellitus, and 53.7% IL-2Rα levels were significantly elevated in patients with ischemic stroke due to large-artery atherosclerosis (53.5±4.7
It has been mentioned that risk due to clonal hematopoiesis is equal in magnitude to conventional risk factors like smoking, hypertension, dyslipidemia and diabetes. They conducted deep sequencing of selected genomic regions in 968 patients with asymptomatic carotid atherosclerosis detected by duplex sonography.
Many of our CMHC faculty who spoke at AHA 2024 are featured in this on-demand program, sharing expertise on key topics in cardiorenal health, obesity, diabetes, dyslipidemia, atherosclerosis, and more. Read the published study. Earn 14 CME credits anytime on any device. Co-chaired by leading experts Peter Libby, MD , Erin D.
White matter hyperintensities (WMH) and cerebral microbleeds (CMB) are manifestations of CSVD.Methods:Using the Atherosclerosis Risk in Communities (ARIC) database, we extracted data from 1112 participants assessed for dental caries and vascular risk factors. Of those, 203 (18.3%) had caries and 909 (81.7%) did not. OR 1.52 (95% 0.96
The expanded risk score includes vascular risk factors, migraine characteristics, and medications used in migraine patients.Methods:We prospectively evaluated participants in Atherosclerosis Risk in Communities Cohort (ARIC) with history of migraine.
The patients were categorized into two groups according to the etiology of the ICA lesion: atherosclerosis and dissection. 467 (88.8%) patients presented with atherosclerosis of the ICA, and 59 (11.2%) patients presented dissection. IQR 44 ‐ 63], p< 001), rates of hypertension (74.5% 001), diabetes (29.8%
There were no differences with rates of hypertension, hyperlipidemia, diabetes, smoking, heart failure, and pulmonary hypertension among MPN Veterans with stroke with and without AO exposure.In The biologic plausibility of endothelial dysfunction and accelerated atherosclerosis from AO exposure warrants further investigation.
2023, the American Heart Association (AHA) issued a presidential advisory on the urgency of this systemic disorder involving heart disease, kidney disease, diabetes and obesity. In its advisory, the AHA stressed an interdisciplinary team approach emphasizing social determinants of health, shortcomings in current efforts, and knowledge gaps.
The HR was nonsignificant after adjustment for age, gender, race, hypertension, diabetes, hypercholesterolemia and smoking status, adjusted HR 1.33 The HR remained significant after adjustment for age, gender and race, adjusted HR 1.72 with a 95% CI of 1.17-2.51. with a 95% CI of 0.89-1.99.Conclusion:We
IntroductionDrug‐eluting stent (DES) use in symptomatic intracranial atherosclerosis disease (ICAD) has been described in the literature using different guiding and distal access catheters. Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023.
Our case describes a patient with right extracranial internal carotid artery (ICA) thrombus secondary to later‐diagnosed CaW on close follow‐up imaging.MethodsWe report a 55‐year‐old African American man with history of hypertension, type 2 diabetes mellitus and hyperlipidemia presented with acute onset slurred speech and left facial droop (FP).
Repeat CTA head and neck demonstrated multifocal intracranial atherosclerosis with marked stenosis of the left V4 segment. However, marked stenosis at V2 appeared to be owed to external compression from facet arthrosis rather than atherosclerosis. Episodes always occurred after activity and only upon sitting.
Background Disruption of lipid metabolism contributes to increased cardiovascular risk in diabetes. Methods We evaluated the associations between serum lipidomic profile and subclinical carotid atherosclerosis (SCA) in type 1 (T1D) and type 2 (T2D) diabetes, and in subjects without diabetes (controls) in a cross-sectional study.
The aim of this study was to identify different patterns of CAC change and evaluate the associations with different cardiovascular outcomes.MethodsData from the Multi-Ethnic Study of Atherosclerosis study were analyzed. Participants with at least three CT measurements were included. The main study outcome is hard cardiovascular disease (CVD).
BackgroundAs a noninvasive, lowcost, nonpharmacological procedure with excellent properties of safety, remote ischemic conditioning (RIC) has been demonstrated to prevent recurrence of stroke among patients with ischemic stroke of large artery atherosclerosis origin.
We aimed to evaluate the association between carotid artery tortuosity and the incidence of ischemic stroke.Methods:We analyzed 3D contrast-enhanced MRA datasets from 2,066 participants enrolled in the Atherosclerosis Risk in Communities (ARIC) Carotid MRI study. fold increased risk of ischemic stroke (95% CI, 1.08-5.61)
In a linear regression model adjusted for age, sex, race, hypertension, diabetes, prior stroke, current smoking, current alcohol use, systolic blood pressure, and APOE genotype, lower eGFR was significantly associated with higher WMH ( = -0.008; 95% CI -0.013, -0.003; p < 0.001) (Figure 2). female, 22.1% female, 22.1%
Introduction:It is known that past the age of 35, the prevalence of large artery atherosclerosis (LAA) related strokes increases with a cardiovascular risk factor (CVRF) profile beginning to resemble that of elderly patients. A significantly larger proportion of patients with LAA had baseline CVRFs including hypertension (80.0%
Incident stroke (ischemic and hemorrhagic) was ascertained until the end of 2021 with adjudication by an expert panel. Cox regression was used to estimate the hazard ratio (HR) for incident stroke per doubling of EIC levels, and p-values were FDR corrected. Results:Among the 9,444 participants included, the mean age was 57 (5.7 SD), and 43.2%
Connecting Risk Factors to Costs The Shaw study reviewed 6,814 asymptomatic participants from the Multi-Ethnic Study of Atherosclerosis (MESA) sponsored by a NIH National Heart, Lung, and Blood Institute. Like age, diabetes, dyslipidemia, and hypertension are also widely accepted as cardiovascular disease factors.
This study explores whether midlife vascular risk factors are associated with risk of PDD in the community-based ARIC cohort.Methods:ARIC participants were evaluated for vascular risk factors (hypertension, diabetes, hypercholesterolemia, smoking, and obesity) in 1987-1989 (ages 44-64) and followed through 2016.
While the exact mechanism underpinning that association is unclear, there is evidence that systemic inflammation contributes to atherosclerosis progression. One measure of subclinical atherosclerosis, carotid artery intima-media thickness (CIMT), is independently associated with ischemic stroke.
This study examined associations of midlife vascular risk factors (VRFs), and the cumulative burden of these factors, with LLD.Methods:Individuals from the Atherosclerosis Risk in Communities (ARIC) Study were evaluated for VRFs (smoking, hypertension, diabetes, hypercholesterolemia, and obesity) at midlife (ages 44-66).
Evidence shows that in diabetic men, intima-media thickness is significantly higher in those with ApoE4 than those with ApoE3. While the link between ApoE4 and extracranial atherosclerosis and vascular risk factors is established, the association of these vascular factors with ICAS is unknown. 0.20, p=0.01.Conclusion:ApoE4
This study aimed to identify potential biomarkers for predicting stroke recurrence.Methods and ResultsWe conducted a nested case–control study using a hospital‐based cohort from the Third China National Stroke Registry selecting 214 age‐ and sex‐matched patients with ischemic stroke with hypertension and no history of diabetes or heart disease.
APOB The fundamental basis of coronary artery disease is when a cholesterol particle is retained in the artery wall, and an inflammatory cascade occurs, resulting in the formation of atherosclerosis. While markers of diabetes are routinely checked, measures of insulin resistance are rarely formally evaluated. 122.025858. JAMA Cardiol.
We organize all of the trending information in your field so you don't have to. Join thousands of users and stay up to date on the latest articles your peers are reading.
You know about us, now we want to get to know you!
Let's personalize your content
Let's get even more personalized
We recognize your account from another site in our network, please click 'Send Email' below to continue with verifying your account and setting a password.
Let's personalize your content