Remove Atherosclerosis Remove Dementia Remove Diet
article thumbnail

Cholesterol’s Star Role in Dementia Prevention: New Insights from the 2024 Lancet Dementia Report 

Cardiometabolic Health Congress

The 2024 report from the Lancet Standing Commission on Dementia Prevention, Intervention, and Care brings promising developments for healthcare professionals and public health advocates. Key Takeaways: Up to 50% of all dementia cases could potentially be prevented or substantially delayed.

article thumbnail

Abstract DP14: Neuroinflammatory mechanisms linking metabolic syndrome with vascular cognitive impairment

Stroke Journal

Background:PCSK9, a key regulator of cholesterol metabolism, has been implicated in atherosclerosis. However, its potential role in vascular cognitive impairment and dementia (VCID) remains elusive. PCSK9 overexpression was induced via AAV injection, and mice were subjected to either a normal diet or HFD for 4 months.

Diet 40
article thumbnail

Beating the Odds: Inside the Tribe with a Near-Zero Rate of Heart Disease.

Dr. Paddy Barrett

Share While the average Western male and female will develop advanced coronary artery disease by age 55 and 66, respectively, 85% of the Tsimane tribe population over 40 had no evidence of advanced atherosclerosis 2. Coronary atherosclerosis, as evidenced by an abnormal CAC score, is a measure of advanced plaque. In my view.