Science Daily - Heart Disease

APRIL 30, 2024

Researchers have discovered that the smooth muscle cells that line the arteries of people with atherosclerosis can change into new cell types and develop traits similar to cancer that worsen the disease.

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Atherosclerosis Cancer Peripheral Arterial Disease Coronary Artery Disease 58

Journal of the American Heart Association

DECEMBER 8, 2023

BackgroundThe relationship between depression and subclinical coronary atherosclerosis in asymptomatic individuals is not clear. The degree and extent of subclinical coronary atherosclerosis were evaluated by coronary computed tomographic angiography, and ≥50% diameter stenosis was defined as significant.

Coronary Artery Disease 40

Coronary Artery Disease Atherosclerosis Plaque Stenosis 40

Physiologically Speaking

DECEMBER 17, 2024

Coronary artery calcium (CAC) is a measure of atherosclerosis and a strong predictor of cardiovascular disease. Notably, athletes engaging in very vigorous-intensity exercise are more likely to develop calcified plaques. However, the composition of the plaques in athletes appears to be more benign.

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Risk Factors Genetic predisposition Plaque Exercise 105

Frontiers in Cardiovascular Medicine

JULY 24, 2024

Although the entire vascular bed is constantly exposed to the same risk factors, atherosclerosis manifests a distinct intra-individual pattern in localization and progression within the arterial vascular bed.

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Atherosclerosis Plaque Coronary Artery Disease Risk Factors 52

Dr. Paddy Barrett

FEBRUARY 27, 2024

The reason: They were accumulating plaque in their coronary arteries much earlier than their peers. You can’t have a heart attack if you don’t have plaque in your coronary arteries. And plaque in your coronary arteries is the result of exposure to risk factors over time.

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Risk Factors Heart Disease Heart Attack Heart attacks 108

Frontiers in Cardiovascular Medicine

MARCH 4, 2024

Atherosclerotic coronary artery disease (CAD) is the causal pathological process driving most major adverse cardiovascular events (MACE) worldwide. The complex development of atherosclerosis manifests as intimal plaque which occurs in the presence or absence of traditional risk factors.

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Plaque Coronary Artery Disease Blood Pressure Cardiovascular Disease 59

DAIC

JANUARY 23, 2024

a leader in non-invasive artificial intelligence (AI) precision coronary solutions, announced FFRCT was transitioned to a Category I Current Procedural Terminology (CPT) code beginning January 1, 2024. milla1cf Tue, 01/23/2024 - 13:44 January 23, 2024 — HeartFlow, Inc. ,

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Reimbursement Coronary Artery Disease CMS Technology 105

Dr. Paddy Barrett

SEPTEMBER 20, 2024

When we say heart disease, what we really mean is plaque in the artery wall. This Is Known As Atherosclerosis. The fundamental cause of atherosclerosis is when a cholesterol particle crosses into the artery wall from the bloodstream, gets stuck, and sets off an inflammatory process 1. No atherosclerosis.

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Heart Disease Cholesterol Atherosclerosis Heart Attack 104

DAIC

MAY 8, 2024

1 Atherosclerosis is a systemic disease that affects multiple vascular regions and is particularly severe in PAD patients, where up to 80 percent suffer from concurrent coronary artery disease (CAD), historically linked with a mortality rate exceeding 50 percent within five years.

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Coronary Artery Disease Chest Pain Ischemia Myocardial Infarction 111

DAIC

OCTOBER 15, 2024

15, 2024 – Elucid has announced that four of the seven Medicare Administrative Contractors (MACs) will extend coverage for AI-enabled quantitative coronary plaque analysis, including its FDA-cleared PlaqueIQ image analysis software, beginning Nov. In the United States, one person dies every 33 seconds from cardiovascular disease.

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Medicare Plaque Chest Pain Coronary Artery Disease 52

Cardiometabolic Health Congress

JUNE 20, 2024

The EAS 2024 Congress (May 26-29, 2024) has concluded, providing critical insights into atherosclerosis and related vascular disease. Giovanna Liuzzo (Italy) revealed that advancements in noninvasive imaging recently allow for direct visualization of coronary atherosclerotic plaques. In contrast, Dr. Michael D.

Atherosclerosis 59

Atherosclerosis Cardiovascular Disease Coronary Artery Disease Myocardial Infarction 59

Dr. Paddy Barrett

APRIL 5, 2024

A common feedback I get is that people with existing coronary artery disease feel like it doesn’t apply to them. Arguably, applying the principles of prevention offers more bang for buck in the short term for people WITH coronary artery disease than those without coronary artery disease.

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Heart Disease Coronary Artery Disease Heart attacks Heart Attack 107

DAIC

JANUARY 23, 2024

Atherosclerotic cardiovascular disease (ASCVD), caused by plaque buildup in arterial walls, is one of the leading causes of disability and death worldwide.1,2 1,6 Until recently atherosclerosis has been thought of as the result of passive lipid accumulation in the vessel wall. 4 In the U.S.

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Cardiovascular Disease Heart attacks Heart Attack Coronary Artery Disease 111

DAIC

FEBRUARY 23, 2024

The Category I CPT code is an addition to the Category III CPT codes (CPT 0623T, 0624T, 0625T, 0626T) used for reporting Cleerly’s advanced coronary atherosclerosis analysis. Derivation, Validation and Prognostic Assessment of an AI-Based Algorithm for Determination of Coronary Ischemia: The CREDENCE and PACIFIC Trial.

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Ischemia Coronary Artery Disease Physiology Cardiovascular Imaging 105

Dr. Paddy Barrett

JUNE 7, 2024

Heart disease is the presence of plaque or atherosclerosis in the coronary arteries. Over a long enough time horizon, pretty much everyone will develop a significant amount of plaque and have a heart attack. On average, they develop serious heart disease about 20 to 25 years later than everyone else 2.

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Heart Disease Heart Attack Heart attacks Plaque 80

Dr. Paddy Barrett

JANUARY 23, 2024

However, most adults will start to develop advanced plaque in their coronary arteries early in life. By age 66, more than half of all females will have evidence of advanced plaque in their coronary arteries, as seen on a CT calcium score. For males, this happens about a decade earlier at age 55 1.

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Heart Disease Blood Pressure Dementia Atherosclerosis 97

DAIC

JUNE 10, 2024

It marks a turning point in reporting of CCTA as it focuses on actual quantification of atherosclerosis.” “This document provides for the first time a standardization on nomenclature for quantitative parameters derived from CCTA,” said Hector Garcia-Garcia , MD, PhD, writing group co-chair and corresponding author. “It

Document 104

Document Coronary Artery Disease Stenosis Atherosclerosis 104

Frontiers in Cardiovascular Medicine

FEBRUARY 5, 2024

Background Kounis syndrome is an acute coronary syndrome (ACS) caused by allergic reactions, including coronary artery spasm (type I) caused by allergies without coronary predisposing factors, pre-existing coronary atherosclerosis, and coronary artery disease.

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Coronary Artery Disease Electrocardiogram Myocardial Infarction Thrombosis 64

Dr. Paddy Barrett

OCTOBER 4, 2024

Everyone starts with no plaque in the coronary arteries, but over a long enough time frame, everyone develops plaque in their coronary arteries. By age 80, almost everyone will have evidence of advanced plaque in their coronary arteries, as defined by a cardiac CT 1.

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Heart Disease Plaque Cholesterol Risk Factors 90

Circulation

NOVEMBER 11, 2024

CCR5, a chemokine receptor, has been associated with both immunosuppressive and inflammatory phenotypes, however, the possible role of CCR5 pertaining to MDSCs in the development of atherosclerosis has not been elucidated yet. Possibly this dysfunctionality contributes to the development and progression of CVD including atherosclerosis.

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Atherosclerosis Plaque Coronary Artery Disease Diet 40

Stroke Journal

FEBRUARY 1, 2024

Background:Lipoprotein a (Lp(a)) is known to be associated with coronary artery disease and carotid artery atherosclerosis. Carotid ultrasound results were divided into two groups based on the presence or absence of plaque. Stroke, Volume 55, Issue Suppl_1 , Page ATP226-ATP226, February 1, 2024.

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Plaque Coronary Artery Disease Ultrasound Atherosclerosis 40

Circulation: Genomic and Precision Medicine

NOVEMBER 28, 2023

BACKGROUND:Individuals with type 2 diabetes (T2D) have an increased risk of coronary artery disease (CAD), but questions remain about the underlying pathology. BothATP1B1andARVCFalso had significantly different associations for CAC in T2D cases versus controls.

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Atherosclerosis Diabetes Plaque Coronary Artery Disease 40

Dr. Paddy Barrett

AUGUST 1, 2023

CT coronary angiography, in addition to a CT CAC, is arguably the best test for estimating whether someone has evidence of coronary artery disease and what that means for their near-term risk of a heart attack. A CT CAC scan can only identify if there is calcified atherosclerosis, where it is and to what extent.

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Coronary Angiogram Plaque Coronary Artery Disease Chest Pain 52

Circulation

JANUARY 15, 2024

Coronary artery calcification (CAC) accompanies the development of advanced atherosclerosis. Nevertheless, the relationship between CAC and the susceptibility of a plaque to provoke a thrombotic event remains incompletely understood. This review summarizes the current understanding and literature on CAC.

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Coronary Artery Disease Atherosclerosis Laboratory Plaque 45

Dr. Smith's ECG Blog

NOVEMBER 15, 2023

Angiogram No obstructive epicardial coronary artery disease Cannot exclude non-ACS causes of troponin elevation including coronary vasospasm, stress cardiomyopathy, microvascular disease, etc. See "Mechanisms of acute coronary syndromes related to atherosclerosis".) Lindahl et al.

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Coronary Angiogram Plaque Thrombosis STEMI 100

Cardiometabolic Health Congress

NOVEMBER 22, 2024

Personalized Cardiometabolic Care TRANSFORM Program for Coronary Artery Disease (CAD) : The TRANSFORM program focuses on atherosclerosis-based care strategies rather than traditional risk-based approaches.

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Blood Pressure Obesity Preserved Ejection Fraction Coronary Artery Disease 59

Stroke Journal

NOVEMBER 9, 2023

The identification of a variant in theHDAC9gene as a risk factor for large-artery atherosclerotic stroke, and subsequently coronary artery disease, has opened novel treatment pathways for stroke and more widely atherosclerotic disease. Indirect data support such an approach in man.

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Stroke Strokes Atherosclerosis Coronary Artery Disease 40

DAIC

MAY 16, 2024

PAD is a serious, progressive cardiovascular disease primarily caused by a buildup of fatty plaque in the blood vessels, or atherosclerosis. This plaque narrows the blood vessels and reduces blood flow to the legs and feet, which may significantly impair physical function, walking performance and quality of life.

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Peripheral Arterial Disease Exercise Ischemia Quality of Life 105

Dr. Paddy Barrett

SEPTEMBER 5, 2023

Share Let’s first state our goal when we are in the business of ‘Heart Disease Prevention’: To delay the onset of coronary artery disease (atherosclerosis/plaque) that might rupture and cause a heart attack. And the less plaque you have, the lower the risk of a heart attack.

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Plaque Heart Attack Heart attacks Exercise 52

Dr. Smith's ECG Blog

MAY 19, 2020

If the arrest was caused by acute MI due to plaque rupture, then the diagnosis is MINOCA. MINOCA: Myocardial Infarction in the Absence of Obstructive Coronary Artery Disease). Here is my comment on MINOCA: "Non-obstructive coronary disease" does not necessarily imply "no plaque rupture with thrombus."

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Defibrillator Circulation Plaque Cardiac Arrest 52

Dr. Smith's ECG Blog

NOVEMBER 30, 2022

Hospital Course The patient was taken emergently to the cath lab which did not reveal any significant coronary artery disease, but she was noted to have reduced EF consistent with Takotsubo cardiomyopathy. To prove there is no plaque rupture, you need to do intravascular ultrasound (IVUS). It can only be seen by IVUS.

Plaque 52

Plaque Chest Pain Thrombosis Stenosis 52

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

The complications of the procedure and patient’s outcomes were discussed.MethodsWe identified two patients who were admitted to our medical center between January 2022 to December 2022 for subclavian‐carotid artery bypass procedure. Clinical data were reviewed retrospectively.ResultsCase 1.

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Outcomes Chest Pain Coronary Artery Disease Aortic 40

Wellnest

DECEMBER 21, 2022

Coronary artery disease Excessive cholesterol builds up plaque that blocks the arteries supplying blood to the heart. This condition is also called atherosclerosis. ECG machine can also help diagnose coronary artery disease. Early detection is vital in the treatment of CAD.

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Cardiac Arrest Heart attacks Heart Attack Atrial Fibrillation 52

Dr. Smith's ECG Blog

APRIL 29, 2020

Angiogram --Minimal coronary atherosclerosis --No obstructive epicardial coronary artery disease or evidence of plaque rupture noted to explain prolonged QT or ventricular fibrillation cardiacarrest, suspect nonischemic mechanism Echo The estimated left ventricular ejection fraction is 45 %.

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Cardiac Arrest Defibrillator Ischemia Tachycardia 52

Dr. Paddy Barrett

MAY 31, 2024

The mistake most people make when it comes to heart disease is thinking that when someone has a heart attack that, the condition of ‘heart disease’ just appeared. But heart disease presents slowly. CT Coronary Angiogram. Atherosclerosis in the proximal segment of the vessel. Here’s why.

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Heart Disease Plaque Heart Attack Heart attacks 81

Coronary Artery Disease Journal

DECEMBER 28, 2023

Purpose To evaluate the association between osteoporosis and coronary calcification and coronary plaque burden in patients with atherosclerosis and coronary artery disease (CAD). Quantitative computed tomography was used to measure the lumbar vertebra’s bone mineral density (BMD). to −0.13; P   0.05).

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Coronary Artery Disease Plaque Atherosclerosis Research 40

Circulation

NOVEMBER 11, 2024

Background:The presence of carotid plaque (CP) may serve as an indicator of panvascular atherosclerosis. However, the observed incongruity between carotid disease and the presence and severity of coronary artery disease (CAD) suggests differing mechanisms. Subsequently, patients were followed for 5.5

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Exercise Coronary Artery Disease Ultrasound Atherosclerosis 40