Dr. Paddy Barrett

DECEMBER 13, 2024

ApoB Atherosclerosis, by definition, is caused by the retention of an ApoB lipid particle in the artery wall. This retained particle then sets off an inflammatory cascade, which ultimately results in the formation of atherosclerosis 1. Mechanism of atherosclerosis formation. Relationship of BMI and Risk Of Diabetes.

Heart Disease 97

Heart Disease BMI Diabetes Cardiovascular Disease 97

Circulation: Genomic and Precision Medicine

NOVEMBER 28, 2023

BACKGROUND:Individuals with type 2 diabetes (T2D) have an increased risk of coronary artery disease (CAD), but questions remain about the underlying pathology. Circulation: Genomic and Precision Medicine, Ahead of Print.

Atherosclerosis 40

Atherosclerosis Diabetes Plaque Coronary Artery Disease 40

DAIC

JANUARY 23, 2024

Atherosclerotic cardiovascular disease (ASCVD), caused by plaque buildup in arterial walls, is one of the leading causes of disability and death worldwide.1,2 1,2 ASCVD causes or contributes to conditions that include coronary artery disease (CAD), cerebrovascular disease, and peripheral vascular disease (inclusive of aortic aneurysm).3

Cardiovascular Disease 111

Cardiovascular Disease Heart attacks Heart Attack Coronary Artery Disease 111

DAIC

MARCH 6, 2024

milla1cf Wed, 03/06/2024 - 18:48 March 6, 2024 — Cleerly , the company on a mission to create a new standard of care to aid in the diagnosis of heart disease, has been granted Breakthrough Device Designation by the U.S. Food and Drug Administration ( FDA ) for its Coronary Artery Disease ( CAD ) Staging System.

Heart Disease 105

Heart Disease Heart attacks Heart Attack Technology 105

MIBHS

FEBRUARY 28, 2025

A family history of heart disease often indicates that genetic factors might be at play. Common Heart Diseases with Genetic Links Coronary Artery Disease (CAD): CAD occurs when the arteries supplying blood to the heart become narrowed or blocked. Mutations can lead to elevated LDL (bad cholesterol) levels.

Genetic predisposition 52

Genetic predisposition Heart Disease Cholesterol Blood Pressure 52

Dr. Paddy Barrett

OCTOBER 4, 2024

But the goal in this instance is to die after a long and healthy life ‘ with ’ coronary artery disease rather than ‘ from ’ coronary artery disease. However, the chances of dying from heart disease are directly proportional to the amount of plaque in your coronary arteries.

Heart Disease 102

Heart Disease Plaque Cholesterol Risk Factors 102

Journal of the American Heart Association

FEBRUARY 26, 2025

BackgroundPlaque progression (PP) is critical between subclinical atherosclerosis and plaque rupture. P=0.006), especially in diabetic patients (Pearsonr=0.58,P<0.001). Journal of the American Heart Association, Ahead of Print. P<0.001).

Ultrasound 56

Ultrasound Plaque Cholesterol Coronary Artery Disease 56

DAIC

MAY 16, 2024

PAD is a serious, progressive cardiovascular disease primarily caused by a buildup of fatty plaque in the blood vessels, or atherosclerosis. Among those ages 65 and older, nearly 50% who underwent limb amputation died within one year after surgery, according to the 2024 Heart Disease and Stroke Statistics: A Report of U.S.

Peripheral Arterial Disease 105

Peripheral Arterial Disease Exercise Ischemia Quality of Life 105

Dr. Paddy Barrett

OCTOBER 31, 2023

An elevated Lp(a) is a common genetic factor that is independently and causally related to premature coronary artery disease. The occurrence of disease in this instance is probabilistic, not deterministic. An elevated Lp(a) does increase the risk of early cardiovascular disease, but that risk is not set in stone.

Coronary Artery Disease 52

Coronary Artery Disease Heart Disease Atherosclerosis Cardiovascular Disease 52

Stroke Journal

FEBRUARY 1, 2024

The expanded risk score includes vascular risk factors, migraine characteristics, and medications used in migraine patients.Methods:We prospectively evaluated participants in Atherosclerosis Risk in Communities Cohort (ARIC) with history of migraine.

Stroke 40

Stroke Strokes Risk Factors Coronary Artery Disease 40

Dr. Paddy Barrett

OCTOBER 10, 2023

Even in those with documented coronary artery disease, less than half were on statin therapy, which has been repeatedly proven to decrease risk in this high-risk group 1. Insulin Resistance Everyone exists along a continuum of insulin sensitive to highly insulin resistant, the later stages being characterised by type 2 diabetes.

Risk Factors 52

Risk Factors Heart Disease Blood Pressure Coronary Artery Disease 52

Circulation

NOVEMBER 11, 2024

Background:The presence of carotid plaque (CP) may serve as an indicator of panvascular atherosclerosis. However, the observed incongruity between carotid disease and the presence and severity of coronary artery disease (CAD) suggests differing mechanisms. Subsequently, patients were followed for 5.5

Exercise 40

Exercise Coronary Artery Disease Ultrasound Plaque 40

DAIC

APRIL 4, 2024

Study Details Researchers at the National Institutes of Health ( NIH ) set out to assess early coronary atherosclerosis burden, and its relation to how the heart is functioning, in people living with HIV who were asymptomatic and had low cardiovascular disease risk. million lives so far. Gharib, M.D. Abd-Elmoniem, Ph.D.,

Coronary Artery Disease 40

Coronary Artery Disease Cardiovascular Disease Cardiothoracic Sudden Cardiac Death 40

Circulation

NOVEMBER 11, 2024

Background:Coronary artery calcification (CAC) is an established marker of subclinical atherosclerosis and predictor of cardiovascular events. The presence of CAC was associated with traditional risk factors including diabetes, smoking, hypertension and LDL-C. were females.

Risk Factors 40

Risk Factors Coronary Artery Disease Atherosclerosis Diabetes 40

Coronary Artery Disease Journal

JUNE 3, 2024

Background Chronic total coronary occlusion (CTO) is an extremely hazardous condition that leads to various clinical phenomena and complications and results in social and economic burdens. Hyperuricemia (HU) is often associated with atherosclerosis. 3.11), while sex, smoking, hypertension, and diabetes did not show similar effects.

Kidney Disease 40

Kidney Disease Atherosclerosis Risk Factors Diabetes 40

Physiologically Speaking

APRIL 24, 2024

6 [link] Insufficient sleep has been linked to a greater risk for several health conditions including obesity, diabetes, hypertension, and cognitive decline. 9 Adults who sleep <6 hours each night have a 15% greater risk for CVD and 23% increased risk for coronary heart disease compared to those sleeping 7 hours or more.

Blood Pressure 52

Blood Pressure Blood Clot COVID-19 Cardiovascular Disease 52

Frontiers in Cardiovascular Medicine

FEBRUARY 18, 2025

ObjectiveMitochondrial dysfunction is associated with increased risk of atherosclerosis by disrupting key cellular processes that contribute to premature vascular ageing. EOCAD patients had lower mtDNA-CN (p<0.001) and higher mtDNA4977 deletion (p=0.026).

Coronary Artery Disease 52

Coronary Artery Disease Risk Factors Obesity Atherosclerosis 52

Heart BMJ

JANUARY 13, 2025

Background The relationship between atherosclerosis and endotypes of myocardial ischaemia with no obstructive coronary artery disease (INOCA) is unclear. Angiographic analyses were performed blind to coronary physiology findings. female) without flow-limiting coronary artery disease, medical history included 41.7%

Plaque 52

Plaque Coronary Artery Disease Angina Physiology 52

Cardiometabolic Health Congress

NOVEMBER 22, 2024

Diabetes and Obesity Care Advancements New Technologies for Diabetes Management : The recent FDA approvals of various insulin delivery devices, including the Embecta patch pump for Type 2 diabetes , have expanded patient options. New developments in continuous glucose monitors (CGMs) have also been transformative.

Blood Pressure 59

Blood Pressure Obesity Preserved Ejection Fraction Coronary Artery Disease 59