Frontiers in Cardiovascular Medicine

FEBRUARY 7, 2024

Background In this study, we aim to investigate the relationship between the attenuation of peri-coronary adipose tissue (PCAT) in patients with suspected coronary artery disease (CAD) and the assessment of coronary vascular functions using coronary flow reserve (CFR). in 206 (57%) patients. HU vs. −77.1 HU;

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Coronary Artery Disease Atherosclerosis Plaque Stenosis 64

Journal of the American Heart Association

DECEMBER 8, 2023

BackgroundThe relationship between depression and subclinical coronary atherosclerosis in asymptomatic individuals is not clear. The degree and extent of subclinical coronary atherosclerosis were evaluated by coronary computed tomographic angiography, and ≥50% diameter stenosis was defined as significant.

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Coronary Artery Disease Atherosclerosis Plaque Stenosis 40

Science Daily - Heart Disease

APRIL 30, 2024

Researchers have discovered that the smooth muscle cells that line the arteries of people with atherosclerosis can change into new cell types and develop traits similar to cancer that worsen the disease.

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Atherosclerosis Cancer Peripheral Arterial Disease Coronary Artery Disease 58

Frontiers in Cardiovascular Medicine

JULY 24, 2024

Although the entire vascular bed is constantly exposed to the same risk factors, atherosclerosis manifests a distinct intra-individual pattern in localization and progression within the arterial vascular bed.

Atherosclerosis 52

Atherosclerosis Plaque Coronary Artery Disease Risk Factors 52

Open Heart

AUGUST 12, 2022

Background Patients with severe atherosclerosis have been found to exhibit considerable changes in blood pressure (BP) between arms. The objective of our study was to investigate the predictive value of interarm blood pressure difference (IABPD) for coronary artery disease (CAD) severity.

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Coronary Artery Disease Blood Pressure Atherosclerosis Hospital 52

DAIC

JANUARY 23, 2024

a leader in non-invasive artificial intelligence (AI) precision coronary solutions, announced FFRCT was transitioned to a Category I Current Procedural Terminology (CPT) code beginning January 1, 2024. milla1cf Tue, 01/23/2024 - 13:44 January 23, 2024 — HeartFlow, Inc. ,

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Reimbursement Coronary Artery Disease CMS Technology 105

Cardiovascular Diabetology

JANUARY 21, 2025

Atherogenic index of plasma (AIP), a novel logarithmic index that combines fasting triglyceride and high-density lipoprotein cholesterol concentrations, is associated with the burden of atherosclerosis.

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Coronary Artery Disease Atherosclerosis Cholesterol Research 52

Frontiers in Cardiovascular Medicine

DECEMBER 9, 2024

BackgroundLow-Density Lipoprotein Cholesterol (LDL-C) is the primary lipid therapy target for coronary artery disease (CAD) patients after percutaneous coronary intervention (PCI).

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Cholesterol Coronary Artery Disease Atherosclerosis Diabetes 98

JAMA Cardiology

NOVEMBER 5, 2024

This unmet clinical need for pharmacotherapeutic strategies tailored specifically to AS has spurred contemporary efforts to unravel the development of this disease from atherosclerosis.

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Atherosclerosis Aortic Stenosis Aortic valve 47

DAIC

JANUARY 9, 2024

Through its AI capability, Cleerly ISCHEMIA determines the likely presence or absence of coronary vessel ischemia based on quantitative measures of atherosclerosis, stenosis, and significant vascular morphology from patients’ CCTA images.

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Ischemia Heart Disease Coronary Artery Disease Atherosclerosis 119

DAIC

MARCH 28, 2024

Collectively, this study shows that Cleerly AI-QCT ISCHEMIA , when used in conjunction with Cleerly LABS, can provide a 3-in-1 approach for the assessment of atherosclerosis, stenosis and ischemia. Earls, MD , Chief Medical Officer of Cleerly.

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Ischemia Chest Pain Atherosclerosis Coronary Artery Disease 110

DAIC

FEBRUARY 23, 2024

The Category I CPT code is an addition to the Category III CPT codes (CPT 0623T, 0624T, 0625T, 0626T) used for reporting Cleerly’s advanced coronary atherosclerosis analysis. Earls, MD , Chief Medical Officer of Cleerly. Bär S, Nabeta T, Maaniitty T. Eur Heart J Cardiovasc Imaging. 2023 Dec 12:jead339. Epub ahead of print.

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Ischemia Coronary Artery Disease Physiology Cardiovascular Imaging 105

Circulation

DECEMBER 28, 2023

Using mediation Mendelian randomization, we explored proteomic mediators of the effects of genetically proxied IL-6 signaling on coronary artery disease, large artery atherosclerotic stroke, and peripheral artery disease.

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Atherosclerosis Peripheral Arterial Disease Coronary Artery Disease Pharmacology 49

Circulation

NOVEMBER 11, 2024

CCR5, a chemokine receptor, has been associated with both immunosuppressive and inflammatory phenotypes, however, the possible role of CCR5 pertaining to MDSCs in the development of atherosclerosis has not been elucidated yet. Possibly this dysfunctionality contributes to the development and progression of CVD including atherosclerosis.

Atherosclerosis 40

Atherosclerosis Plaque Coronary Artery Disease Diet 40

Dr. Paddy Barrett

FEBRUARY 27, 2024

Presence of atherosclerosis with LDL-C and HBA1c in the ‘normal range’ What the above graph shows is that for those with an LDL-C of 3.4 mmol/l (130 mg/dl) or below, between 20-50% will already have coronary artery disease. For many of our traditional risk factors, normal does not mean optimal 4. JAMA Cardiol.

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Risk Factors Heart Disease Heart Attack Heart attacks 112

DAIC

JUNE 10, 2024

It marks a turning point in reporting of CCTA as it focuses on actual quantification of atherosclerosis.” “This document provides for the first time a standardization on nomenclature for quantitative parameters derived from CCTA,” said Hector Garcia-Garcia , MD, PhD, writing group co-chair and corresponding author. “It

Document 104

Document Coronary Artery Disease Stenosis Atherosclerosis 104

Cardiovascular Diabetology

FEBRUARY 19, 2024

The atherogenic index of plasma (AIP) represents a marker reflecting atherosclerosis. The triglyceride-glucose (TyG) index is considered a dependable biomarker for gauging insulin resistance. However, there is.

Coronary Artery Disease 52

Coronary Artery Disease Atherosclerosis Biomarkers Research 52

Frontiers in Cardiovascular Medicine

FEBRUARY 5, 2024

Background Kounis syndrome is an acute coronary syndrome (ACS) caused by allergic reactions, including coronary artery spasm (type I) caused by allergies without coronary predisposing factors, pre-existing coronary atherosclerosis, and coronary artery disease.

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Coronary Artery Disease Electrocardiogram Myocardial Infarction Thrombosis 64

MIBHS

FEBRUARY 15, 2025

Artery Damage : Hypertension damages the inner lining of your arteries, making them less elastic and more prone to plaque buildup. This condition, called atherosclerosis, narrows the arteries, restricting blood flow and increasing the risk of heart attacks and strokes.

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Blood Pressure Hypertension Chest Pain Aneurysm 52

DAIC

JULY 25, 2024

algorithm is useful in the process of identifying patients with undiagnosed Coronary Artery Disease (CAD) and that AI integrated into the EMR can positively impact population health goals. This observational study demonstrated that the Nanox.AI

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Innovation Coronary Artery Disease Hospital Cardiovascular Disease 105

Stroke Journal

FEBRUARY 1, 2024

Background:Clinical evidence supports the role of Inflammation in atherosclerosis and associated complications. Colchicine as a potential anti-inflammatory treatment among such patients has attracted much attention in recent years.

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Coronary Artery Disease Stroke Strokes Myocardial Infarction 40

Clinical Trial Results

MARCH 31, 2025

MattBudoffEKSTROM ACC 2025 FINAL Download Disclosures: TBD

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Coronary Artery Disease Download Atherosclerosis 40

Circulation: Genomic and Precision Medicine

NOVEMBER 28, 2023

BACKGROUND:Individuals with type 2 diabetes (T2D) have an increased risk of coronary artery disease (CAD), but questions remain about the underlying pathology. Circulation: Genomic and Precision Medicine, Ahead of Print.

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Atherosclerosis Diabetes Plaque Coronary Artery Disease 40

Circulation: Genomic and Precision Medicine

JULY 6, 2023

Circulation: Genomic and Precision Medicine, Volume 16, Issue 5 , Page 480-482, October 1, 2023.

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Coronary Artery Disease Cholesterol Atherosclerosis Circulation 40

Frontiers in Cardiovascular Medicine

OCTOBER 13, 2024

ObjectiveThe present study aimed at evaluating the association between sympathetic nervous system activation (SNS) and the severity of coronary artery disease (CAD).

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Coronary Artery Bypass Graft Atherosclerosis Biomarkers Coronary Artery Disease 52

Frontiers in Cardiovascular Medicine

MARCH 4, 2024

Atherosclerotic coronary artery disease (CAD) is the causal pathological process driving most major adverse cardiovascular events (MACE) worldwide. The complex development of atherosclerosis manifests as intimal plaque which occurs in the presence or absence of traditional risk factors.

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Plaque Coronary Artery Disease Blood Pressure Cardiovascular Disease 59

Medical Xpress - Cardiology

FEBRUARY 26, 2025

Coronary artery disease (CAD), or the narrowing of the coronary arteries, is the leading cause of morbidity and mortality throughout the world.

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Coronary Artery Disease Heart Disease Plaque Atherosclerosis 40

DAIC

MARCH 6, 2024

milla1cf Wed, 03/06/2024 - 18:48 March 6, 2024 — Cleerly , the company on a mission to create a new standard of care to aid in the diagnosis of heart disease, has been granted Breakthrough Device Designation by the U.S. Food and Drug Administration ( FDA ) for its Coronary Artery Disease ( CAD ) Staging System.

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Heart Disease Heart Attack Heart attacks Technology 105

Frontiers in Cardiovascular Medicine

APRIL 10, 2025

Dilated cardiomyopathy (DCM) is characterized by impaired expansion or contraction of the left or both ventricles in the absence of abnormal load conditions (such as primary valve disease) or severe coronary artery disease that can lead to ventricular remodeling.

Heart Failure 40

Heart Failure Cardiomyopathy Coronary Artery Disease Atherosclerosis 40

Journal of the American Heart Association

FEBRUARY 26, 2025

BackgroundPlaque progression (PP) is critical between subclinical atherosclerosis and plaque rupture. After multivariate adjustment, every 0.1mmol/L increase in timeaveraged sdLDLC conferred a 1.2fold increased risk of PP.ConclusionsOur findings suggest that sdLDLC is an independent risk factor of PP in patients with coronary artery disease.

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Ultrasound Plaque Cholesterol Coronary Artery Disease 56

Dr. Paddy Barrett

DECEMBER 13, 2024

ApoB Atherosclerosis, by definition, is caused by the retention of an ApoB lipid particle in the artery wall. This retained particle then sets off an inflammatory cascade, which ultimately results in the formation of atherosclerosis 1. Mechanism of atherosclerosis formation. Atherosclerosis. 2021 , 22 , 5770.

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Stroke Journal

MARCH 23, 2025

The longstanding benefits of percutaneous angioplasty and stenting in coronary artery disease, where atherosclerosis is the overarching cause in nearly all cases, provided a compelling rationale for exploring similar interventions in intracranial atherosclerotic stenosis.

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Angioplasty Stenosis Coronary Artery Disease Stents 40

Circulation

JANUARY 15, 2024

Coronary artery calcification (CAC) accompanies the development of advanced atherosclerosis.

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Coronary Artery Disease Atherosclerosis Laboratory Plaque 45

All About Cardiovascular System and Disorders

SEPTEMBER 29, 2023

Climbing more than five flights of stairs every day can reduce the risk of atherosclerotic cardiovascular disease by over 20% according to a study using data from the UK Biobank, published in the journal Atherosclerosis [1]. Similar results were noted for both coronary artery disease and ischemic stroke.

Heart Disease 52

Heart Disease Coronary Artery Disease Cardiovascular Disease Atherosclerosis 52

Stroke Journal

NOVEMBER 9, 2023

The identification of a variant in theHDAC9gene as a risk factor for large-artery atherosclerotic stroke, and subsequently coronary artery disease, has opened novel treatment pathways for stroke and more widely atherosclerotic disease. Stroke, Volume 54, Issue 12 , Page 3182-3189, December 1, 2023.

Stroke 40

Stroke Strokes Atherosclerosis Coronary Artery Disease 40

Stroke Journal

FEBRUARY 1, 2024

Background:Lipoprotein a (Lp(a)) is known to be associated with coronary artery disease and carotid artery atherosclerosis. Stroke, Volume 55, Issue Suppl_1 , Page ATP226-ATP226, February 1, 2024.

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Plaque Coronary Artery Disease Ultrasound Atherosclerosis 40

Dr. Paddy Barrett

OCTOBER 31, 2023

An elevated Lp(a) is a common genetic factor that is independently and causally related to premature coronary artery disease. The occurrence of disease in this instance is probabilistic, not deterministic. An elevated Lp(a) does increase the risk of early cardiovascular disease, but that risk is not set in stone.

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