Circulation

DECEMBER 28, 2023

Circulation, Ahead of Print. Our analyses suggest the interferon-γ–inducible chemokine CXCL10 to be a potentially causal mediator for atherosclerosis in 3 vascular compartments and, as such, could serve as a promising drug target for atheroprotection.

Atherosclerosis 49

Atherosclerosis Peripheral Arterial Disease Coronary Artery Disease Pharmacology 49

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4132968-A4132968, November 12, 2024. CCR5, a chemokine receptor, has been associated with both immunosuppressive and inflammatory phenotypes, however, the possible role of CCR5 pertaining to MDSCs in the development of atherosclerosis has not been elucidated yet. 3ng/day for 15 days).M-MDSCs

Atherosclerosis 40

Atherosclerosis Plaque Coronary Artery Disease Diet 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4129709-A4129709, November 12, 2024. Background:The current unmet needs for aspirin usage in atherosclerosis lie in its short half-life and narrow indication for anti-platelet effects.

Atherosclerosis 40

Atherosclerosis Circulation Diet Ischemia 40

Heart BMJ

SEPTEMBER 25, 2024

We aimed to synthesise existing evidence on the observational and genetic associations between circulating proteins and CMD. Two investigators independently extracted study characteristics using a standard form and pooled data using random effects models.

Circulation 52

Circulation Biomarkers Heart Failure Atrial Fibrillation 52

Circulation

DECEMBER 17, 2024

Circulation, Ahead of Print. However, the role of METTL4-mediated mitoepigenetic regulation in atherosclerosis is still unknown. We explored the mechanism of METTL4 involvement in atherosclerosis usingMettl4Mac-KO-Apoe-/-andMettl4MUT-Apoe-/-mice and cell models, as well as bone marrow transplantation.

Atherosclerosis 40

Atherosclerosis Transplant Plaque Pharmacology 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4122717-A4122717, November 12, 2024. Recent studies implicate EndMT in atherosclerosis development. Diabetes is associated with both EndMT as well as accelerated atherosclerosis.

Atherosclerosis 40

Atherosclerosis Diabetes Aortic Cardiovascular Disease 40

Circulation: Cardiovascular Imaging

JANUARY 8, 2025

Circulation: Cardiovascular Imaging, Ahead of Print. This can manifest as a multitude of pathologies including left ventricular dysfunction, myocarditis, cardiomyopathy, accelerated atherosclerosis, and coronary vasospasm.

Cardio Oncology 40

Cardio Oncology Atherosclerosis Cardiomyopathy Cancer 40

Frontiers in Cardiovascular Medicine

DECEMBER 5, 2024

The fundamental role of qualitative alterations of lipoproteins in the early development of atherosclerosis has been widely demonstrated. However, the corresponding studies are scarcer in the field of ischemic stroke, despite carotid arteriosclerosis progression underlies at least 20% of ischemic strokes.

Circulation 40

Circulation Stroke Strokes Atherosclerosis 40

Cardiovascular Diabetology

NOVEMBER 29, 2024

The asialoglycoprotein receptor 1 (ASGR1), a multivalent carbohydrate-binding receptor that primarily is responsible for recognizing and eliminating circulating glycoproteins with exposed galactose (Gal) or N-ace.

Atherosclerosis 52

Atherosclerosis Circulation Research 52

Circulation

JUNE 9, 2024

Circulation, Volume 149, Issue 24 , Page 1899-1902, June 11, 2024.

Atherosclerosis 49

Atherosclerosis Circulation 49

Circulation

MARCH 23, 2025

Circulation, Volume 151, Issue 12 , Page e764-e764, March 25, 2025.

Article 49

Article Dementia Atherosclerosis Circulation 49

Circulation

MARCH 23, 2025

Circulation, Volume 151, Issue 12 , Page e766-e766, March 25, 2025.

Article 49

Article Dementia Atherosclerosis Circulation 49

DAIC

MARCH 28, 2024

Collectively, this study shows that Cleerly AI-QCT ISCHEMIA , when used in conjunction with Cleerly LABS, can provide a 3-in-1 approach for the assessment of atherosclerosis, stenosis and ischemia. Circulation. Earls, MD , Chief Medical Officer of Cleerly. Gulati M, Levy PD, Mukherjee D, et al. 2021 Nov 30;144(22):e368-e454.

Ischemia 110

Ischemia Chest Pain Atherosclerosis Coronary Artery Disease 110

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4142898-A4142898, November 12, 2024. Introduction:It remains uncertain whether dietary supplementation of marine n-3 polyunsaturated fatty acids (PUFAs) improves atherosclerosis and lipoprotein subclasses in patients with type 2 diabetes (T2D). day) or low-dose (1.5g/day)

Atherosclerosis 40

Atherosclerosis Diabetes Plaque Cholesterol 40

Circulation

MARCH 9, 2025

Circulation, Volume 151, Issue 10 , Page e709-e709, March 11, 2025.

Atherosclerosis 45

Atherosclerosis Circulation 45

Circulation

MARCH 23, 2025

Circulation, Volume 151, Issue 12 , Page e765-e765, March 25, 2025.

Article 45

Article Dementia Atherosclerosis Circulation 45

Circulation: Genomic and Precision Medicine

NOVEMBER 28, 2023

Circulation: Genomic and Precision Medicine, Ahead of Print. BACKGROUND:Individuals with type 2 diabetes (T2D) have an increased risk of coronary artery disease (CAD), but questions remain about the underlying pathology.

Atherosclerosis 40

Atherosclerosis Diabetes Plaque Coronary Artery Disease 40

Frontiers in Cardiovascular Medicine

OCTOBER 13, 2024

Systemic activation of the SNS was estimated through circulating levels of norepinephrine (NE). Elevated levels of circulating pro-inflammatory markers were significantly correlated with increased NE concentrations (for IL-1β: p < 0.001, r = 0.49; for IL-6 and NE: p = 0.003, r = 0.32; for HIF-1α and NE: p = 0.049, r = 0.21).

Coronary Artery Bypass Graft 52

Coronary Artery Bypass Graft Atherosclerosis Biomarkers Coronary Artery Disease 52

Stroke Journal

FEBRUARY 1, 2024

Background:Most ischemic strokes are caused by atherosclerosis. Apolipoprotein E (ApoE) regulates lipid metabolism, and its deficiency is associated with dyslipidemia and atherosclerosis. Poor dietary habits promote the onset of atherosclerosis. Targeted proteomic profiling identified the circulating inflammatory proteins.

Atherosclerosis 40

Atherosclerosis Risk Factors Diet Plaque 40

Dr. Paddy Barrett

FEBRUARY 27, 2024

Presence of atherosclerosis with LDL-C and HBA1c in the ‘normal range’ What the above graph shows is that for those with an LDL-C of 3.4 4 Primary Prevention of Subclinical Atherosclerosis in Young Adults: JACC Review Topic of the Week. Circulation. The same holds true for HBA1c levels in the normal range.

Risk Factors 112

Risk Factors Heart Disease Heart Attack Heart attacks 112

Circulation

APRIL 7, 2024

Circulation, Volume 149, Issue 15 , Page 1202-1204, April 9, 2024.

Atherosclerosis 45

Atherosclerosis Circulation 45

Stroke Journal

JANUARY 30, 2025

Background:The mechanisms by which intracranial atherosclerosis (ICAS) contributes to large-vessel occlusion strokes (LVOS) remains unclear. Stroke, Volume 56, Issue Suppl_1 , Page AWP260-AWP260, February 1, 2025.

Atherosclerosis 40

Atherosclerosis Stroke Strokes Atrial Fibrillation 40

Circulation

APRIL 6, 2025

Circulation, Volume 151, Issue 14 , Page e922-e922, April 8, 2025.

Thrombosis 45

Thrombosis Atherosclerosis Circulation 45

Dr. Paddy Barrett

DECEMBER 13, 2024

When it comes to cardiovascular disease, two of the biggest risk factors we must consider are: ApoB concentration - A measure of the number of circulating lipid particles. ApoB Atherosclerosis, by definition, is caused by the retention of an ApoB lipid particle in the artery wall. Mechanism of atherosclerosis formation.

Heart Disease 98

Heart Disease BMI Diabetes Cardiovascular Disease 98

Dr. Smith's ECG Blog

MAY 19, 2020

Nonobstructive coronary disease by coronary angiography should be differentiated between patients with normal coronary arteries and minimal luminal irregularities (less than 30% stenosis) and mild to moderate coronary atherosclerosis (30% to less than 50%). FFR can be useful.

Defibrillator 52

Defibrillator Circulation Plaque Cardiac Arrest 52

Stroke Journal

APRIL 3, 2024

Steno-occlusive changes in the posterior cerebral arteries (PCAs) may contribute to worsened outcomes in patients with MMD; however, there is little information on the incidence and natural history of posterior circulation MMD (PCMMD).

Circulation 40

Circulation Outcomes Academic Atherosclerosis 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4144040-A4144040, November 12, 2024. Background:Coronary heart disease (CHD) remains the primary cause of mortality and morbidity in the USA. Although rodents are widely used to explore mechanisms, they have major biological differences with humans.

Plaque 40

Plaque Atherosclerosis Heart Disease Circulation 40

Circulation: Cardiovascular Imaging

SEPTEMBER 16, 2024

Circulation: Cardiovascular Imaging, Volume 17, Issue 9 , Page e017376, September 1, 2024.

Atherosclerosis 40

Atherosclerosis Cardiovascular Imaging Circulation 40

Circulation: Heart Failure

MARCH 8, 2024

Circulation: Heart Failure, Ahead of Print. Background:Current prevalence estimates of heart failure (HF) are primarily based on self-report or HF hospitalizations. Results:Median age was 73 (25th–75th percentile 67–81) years, 53.2% were female, 25.6% were Black, 12.8% were Chinese, and 40.0% were White.

Heart Failure 40

Heart Failure Atherosclerosis Kidney Disease Risk Factors 40

CTVS

SEPTEMBER 17, 2024

PAD is a serious condition affecting circulation and blood vessels, causing them to narrow from plaque buildup in the arteries and blocking blood flow to the extremities, typically the legs and feet. It is triggered by atherosclerosis, which occurs when fatty deposits or cholesterol accumulates… Source

Peripheral Arterial Disease 52

Peripheral Arterial Disease Plaque Atherosclerosis Cholesterol 52

Circulation: Cardiovascular Imaging

JANUARY 11, 2024

Circulation: Cardiovascular Imaging, Ahead of Print. BACKGROUND:Intensive lipid-lowering therapy may induce coronary atherosclerosis regression. Nevertheless, the factors underlying the effect of lipid-lowering therapy on disease regression remain poorly characterized.

Plaque 40

Plaque Atherosclerosis Cardiovascular Imaging Cardiovascular Disease 40

Circulation: Cardiovascular Imaging

FEBRUARY 5, 2025

Circulation: Cardiovascular Imaging, Ahead of Print.

Article 40

Article Cardiovascular Imaging Atherosclerosis Circulation 40

Dr. Smith's ECG Blog

SEPTEMBER 18, 2024

Thus, angiography may be fairly accurate in determining lumen size, but it will not detect the “volume” of atherosclerosis present. If the adjacent segment has some mild luminal narrowing, the amount of arterial luminal narrowing compared with a totally normal artery will also be underestimated.

Ischemia 121

Ischemia Plaque Stenosis Myocardial Infarction 121

Stroke Journal

FEBRUARY 1, 2024

Inclusion criteria: patients with anterior circulation stroke with concomitant extracranial internal carotid artery (ICA) disease with 70-100% stenosis per NASCET criteria and patients who underwent computed tomography perfusion (CTP) before EVT.

Atherosclerosis 40

Atherosclerosis Stroke Strokes Stenosis 40

DAIC

FEBRUARY 3, 2025

et al, Lipoprotein(a) in atherosclerotic cardiovascular disease and aortic stenosis: a European Atherosclerosis Society consensus statement , European Heart Journal, Volume 43, Issue 39, 14 October 2022, Pages 39253946 Koschinsky ML et al. Circulation. 2022 Aug, 80 (9) 934946 Kronenberg F. Arnett DK et al. doi: 10.1161/CIR.0000000000000677.

Cardiovascular Disease 52

Cardiovascular Disease Aortic valve Biomarkers Innovation 52

Circulation: Cardiovascular Imaging

FEBRUARY 5, 2025

Circulation: Cardiovascular Imaging, Ahead of Print.

Cardiovascular Imaging 40

Cardiovascular Imaging Article Atherosclerosis Circulation 40

Circulation: Cardiovascular Quality & Outcomes

FEBRUARY 15, 2024

Circulation: Cardiovascular Quality and Outcomes, Ahead of Print.

Angina 40

Angina Atherosclerosis Circulation Outcomes 40