AMS Cardiology

JANUARY 21, 2023

We all want to be heart-healthy and ensuring our cholesterol levels are in the normal range is one of the most critical steps. High cholesterol can increase your risk of severe conditions like heart disease and heart attacks. Continue reading to learn four heart-healthy habits that can improve your cholesterol.

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DAIC

JANUARY 23, 2024

3 Patients with ASCVD are at a higher risk for major adverse cardiovascular events (MACE) including heart attack or myocardial infarction (MI), stroke, and cardiovascular (CV) death.4 1,6 Until recently atherosclerosis has been thought of as the result of passive lipid accumulation in the vessel wall. 4 In the U.S.

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Frontiers in Cardiovascular Medicine

DECEMBER 5, 2024

The fundamental role of qualitative alterations of lipoproteins in the early development of atherosclerosis has been widely demonstrated. However, the corresponding studies are scarcer in the field of ischemic stroke, despite carotid arteriosclerosis progression underlies at least 20% of ischemic strokes.

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Stroke Journal

NOVEMBER 9, 2023

Stroke, Volume 54, Issue 12 , Page 3182-3189, December 1, 2023. The identification of a variant in theHDAC9gene as a risk factor for large-artery atherosclerotic stroke, and subsequently coronary artery disease, has opened novel treatment pathways for stroke and more widely atherosclerotic disease.

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Journal of the American Heart Association

DECEMBER 19, 2024

BackgroundElevated lowdensity lipoprotein cholesterol is a risk factor for atherosclerotic cardiovascular disease, including acute ischemic stroke (AIS), due to large and smallvessel disease. Cholesterol management guidelines recommend lipidlowering therapy (LLT) to prevent atherosclerotic cardiovascular disease events.

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Dr. Paddy Barrett

OCTOBER 4, 2024

Controlling LDL cholesterol. Let's take a 42-year-old male with an LDL cholesterol of 5.1 How much would they benefit from going on a cholesterol lowering medication? Now add in an elevated Lp(a), which is a common genetic cholesterol particle disorder, and that risk reduction gets even bigger. Being active. Not smoking.

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Dr. Sanjay Gupta

DECEMBER 19, 2022

Today’s video is on the subject of stroke and in particular cryptogenic strokes. It is therefore crucial to identify the cause of stroke and treat the underlying cause wherever possible. Strokes are characterised by death of brain cells as a result of disruption of blood supply to those cells.

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DAIC

MAY 16, 2024

A new joint guideline from the American Heart Association (AHA), the American College of Cardiology (ACC) and nine other medical societies reports early diagnosis and treatment of peripheral artery disease is essential to improve outcomes and reduce amputation risk, heart attack, stroke and death for people with Peripheral Artery Disease (PAD).

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GEMMS

NOVEMBER 22, 2023

Good cardiovascular health is essential for maintaining a healthy lifestyle and reducing the risk of heart disease, stroke, and other cardiovascular conditions. Maintaining cardiovascular health reduces the risk of developing various heart diseases, including heart attack, stroke, and high blood pressure.

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All About Cardiovascular System and Disorders

DECEMBER 15, 2023

CLEAR Trial of Bempedoic Acid Bempedoic acid is an ATP citrate lyase inhibitor, acting upstream of HMGCoA reductase targeted by statins, and reduces LDL cholesterol levels. There were no significant effects on fatal or nonfatal stroke, death from cardiovascular causes and death from any cause. Nat Commun. 2016 Nov 28;7:13457.

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Dr. Paddy Barrett

SEPTEMBER 19, 2023

I do apologise for being direct, but this issue is one of the most frequent barriers I encounter to initiating cholesterol-lowering therapy. A therapy that has been proven repeatedly to reduce the probability of heart attacks and strokes in multiple double-blind randomised controlled studies 1. Let’s break this down.

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MIBHS

AUGUST 15, 2024

Blood Vessels: Chronic stress can impair the function of the endothelium—the lining of blood vessels—potentially leading to atherosclerosis, a precursor to heart disease. Lipid Metabolism: Chronic stress can alter lipid metabolism, potentially increasing bad cholesterol (LDL) and decreasing good cholesterol (HDL).

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Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP318-ATP318, February 1, 2025. Introduction:Elevated Low-Density-Lipoprotein Cholesterol (LDL-C) blood levels are a risk factor for atherosclerosis. Lipid-lowering therapies mitigate the risk of atherothrombotic events.

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Heart 2023 Conference

APRIL 20, 2022

(Naturopathic Medicine) According to a subanalysis of a randomised study, low-dose edoxaban (Savaysa) was related with a reduced stroke risk and a negligible increase in bleeding in older Afib patients at high bleeding risk.

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DAIC

JANUARY 30, 2024

Clinicians currently use two separate risk models to assess patients’ chances of having heart attacks , strokes , and other major cardiovascular events. Using a dataset from a different study, the Multi-Ethnic Study of Atherosclerosis , the team validated the accuracy of their model and overall findings.

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP226-ATP226, February 1, 2024. Background:Lipoprotein a (Lp(a)) is known to be associated with coronary artery disease and carotid artery atherosclerosis.

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Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP14-ADP14, February 1, 2025. Background:PCSK9, a key regulator of cholesterol metabolism, has been implicated in atherosclerosis. However, its potential role in vascular cognitive impairment and dementia (VCID) remains elusive.

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DAIC

MARCH 31, 2025

The study, Effect of Colchicine on Progression of Known Coronary Atherosclerosis in Patients With Stable Coronary Artery Disease Compared To Placebo: The Ekstrom Trial, was presented at the American College of Cardiology 74th Annual Scientific Session and Expo ( ACC.25 These new data reinforce the use of LODOCO(colchicine, 0.5

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Dr. Paddy Barrett

AUGUST 1, 2023

A CT CAC scan can only identify if there is calcified atherosclerosis, where it is and to what extent. First off, CTCA is a noninvasive test, and many patients with chest pain would previously have needed invasive angiography with all the risks it entails, including heart attack, stroke and death (albeit very rare). And it matters.

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Dr. Paddy Barrett

JULY 12, 2024

If you have high LDL cholesterol and are unsure what that means for your risk of heart disease, this article is for you. Over the course of your lifetime, your LDL cholesterol will slowly increase. By midlife, the average male and female will see a significant rise in their LDL cholesterol. to 4 mmol (135 to 155 mg/dl).

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Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP388-AWP388, February 1, 2025. Incident stroke (ischemic and hemorrhagic) was ascertained until the end of 2021 with adjudication by an expert panel. Cox regression was used to estimate the hazard ratio (HR) for incident stroke per doubling of EIC levels, and p-values were FDR corrected.

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Dr. Paddy Barrett

OCTOBER 10, 2023

Lipoprotein (a) Approximately 1 in 5 people have the Lp(a) variant of cholesterol particle that significantly increases the risk of early heart disease and stroke. Blood Pressure Control For every 20 mmHg increase in systolic blood pressure, the risk of dying from heart attack or stroke doubles 3. J Am Coll Cardiol.

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Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP239-AWP239, February 1, 2024. Introduction:Apolipoprotein E4 (ApoE4) allele is linked to increased LDL-Cholesterol, one of the main risk factors for intracranial large artery stenosis (ICAS). Whether these interactions influence the risk of stroke and dementia should be further investigated.

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Stroke Journal

JANUARY 21, 2024

Stroke, Volume 55, Issue 2 , Page 269-277, February 1, 2024. BACKGROUND:Sex-specific differences in plaque composition and instability underscore the need to explore circulating markers for better prediction of high-risk plaques.

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Cardiometabolic Health Congress

NOVEMBER 22, 2024

Another promising advancement is MK-0616 , an oral PCSK9 inhibitor in Phase 3 trials, showing a significant reduction in LDL cholesterol, which provides a more convenient alternative to current injection-based therapies​. The trial highlights the importance of reevaluating and optimizing thrombolytic therapies for better patient outcomes.

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