Cardiometabolic Health Congress

AUGUST 23, 2024

Updated with the latest research since the 2020 edition, this comprehensive report underscores the potential to prevent or significantly delay dementia by targeting modifiable risk factors. The report now identifies 14 modifiable risk factors for dementia. Presented by Pamela B.

Dementia 52

Dementia Cholesterol Risk Factors CME 52

Frontiers in Cardiovascular Medicine

DECEMBER 14, 2023

Background Inflammation and lipid infiltration play crucial roles in the development of atherosclerosis. The monocyte to high-density lipoprotein cholesterol ratio (MHR) was identified as a stronger independent risk factor for CHD.

Heart Disease 64

Heart Disease Cholesterol Stenosis Atherosclerosis 64

Physiologically Speaking

JANUARY 5, 2024

One of the biggest risk factors for CVD development is the buildup of plaque in the coronary arteries (the arteries surrounding the heart that provide it with its own blood supply). LDL and ApoB — which play an obligate and causal role in the development of atherosclerosis — weren’t affected by exercise.

Plaque 119

Plaque Physiology Exercise Cholesterol 119

Circulation

JANUARY 24, 2024

METHODS:The AHA, through its Epidemiology and Prevention Statistics Committee, continuously monitors and evaluates sources of data on heart disease and stroke in the United States and globally to provide the most current information available in the annual Statistical Update with review of published literature through the year before writing.

Heart Disease 81

Heart Disease Peripheral Arterial Disease Stroke Strokes 81

Frontiers in Cardiovascular Medicine

MARCH 4, 2024

The complex development of atherosclerosis manifests as intimal plaque which occurs in the presence or absence of traditional risk factors. For cardiovascular disease, only low-density lipoprotein cholesterol and blood pressure are approved as surrogates for cardiovascular disease.

Plaque 59

Plaque Coronary Artery Disease Blood Pressure Cardiovascular Disease 59

Coronary Artery Disease Journal

DECEMBER 1, 2024

Background Lipoprotein(a) [Lp(a)] is an independent risk factor for cardiovascular disease due to its unique apo(a) component and its association with atherosclerosis and thrombogenesis. to 1.20), total cholesterol, triglycerides, and Lp(a) levels while increasing high-density lipoprotein cholesterol levels.

Heart Disease 40

Heart Disease Cholesterol Myocardial Infarction Atherosclerosis 40

Stroke Journal

NOVEMBER 9, 2023

The identification of a variant in theHDAC9gene as a risk factor for large-artery atherosclerotic stroke, and subsequently coronary artery disease, has opened novel treatment pathways for stroke and more widely atherosclerotic disease. Stroke, Volume 54, Issue 12 , Page 3182-3189, December 1, 2023.

Stroke 40

Stroke Strokes Atherosclerosis Coronary Artery Disease 40

GEMMS

NOVEMBER 22, 2023

Risk factors for cardiovascular disease Understanding the risk factors for cardiovascular disease is crucial for maintaining optimal cardiovascular health. While some risk factors, such as age and family history, cannot be changed, others are within our control.

Blood Pressure 52

Blood Pressure Cholesterol Diet Exercise 52

MIBHS

AUGUST 15, 2024

Effects on Cardiovascular Health Blood Pressure: Cortisol helps regulate blood pressure, but chronic elevation can lead to persistent high blood pressure, a major risk factor for heart disease. Chronic inflammation is a known risk factor for heart disease and other metabolic disorders.

Blood Pressure 52

Blood Pressure Cholesterol Heart Disease Diet 52

Journal of the American Heart Association

DECEMBER 19, 2024

BackgroundElevated lowdensity lipoprotein cholesterol is a risk factor for atherosclerotic cardiovascular disease, including acute ischemic stroke (AIS), due to large and smallvessel disease. Cholesterol management guidelines recommend lipidlowering therapy (LLT) to prevent atherosclerotic cardiovascular disease events.

Stroke 40

Stroke Strokes Cholesterol Cardiovascular Disease 40

Dr. Paddy Barrett

AUGUST 22, 2023

Every lipoprotein particle has one APO B protein. ( **Please note the B ) When we measure APO B levels, this is what we are measuring to give an estimate of the number of cholesterol particles and the subsequent risk of cardiovascular disease. APO E is also centrally involved in cholesterol metabolism. Here’s how.

Cholesterol 52

Cholesterol Dementia Coronary Artery Disease Cardiovascular Disease 52

Stroke Journal

JANUARY 30, 2025

Introduction:Elevated Low-Density-Lipoprotein Cholesterol (LDL-C) blood levels are a risk factor for atherosclerosis. Lipid-lowering therapies mitigate the risk of atherothrombotic events. Stroke, Volume 56, Issue Suppl_1 , Page ATP318-ATP318, February 1, 2025.

Stenosis 40

Stenosis Atherosclerosis Cholesterol Ischemia 40

Dr. Paddy Barrett

FEBRUARY 14, 2025

“Cholesterol does not cause heart disease.“ “Cholesterol doesn’t cause heart disease” The argument goes like this. “If cholesterol causes heart disease, why is it that about half of all patients with a heart attack have normal cholesterol? But other factors also play a role.

Cholesterol 114

Cholesterol Heart Disease Heart Attack Heart attacks 114

The British Journal of Cardiology

AUGUST 1, 2024

Management of high levels encourages rigorous attention to correction of other risk factors, such as blood pressure, smoking and low-density lipoprotein (LDL). Currently, there is no specific treatment to lower its circulating concentration. Raised Lp(a) is a feature of familial hypercholesterolaemia.

Aortic valve 40

Aortic valve Heart Disease Blood Pressure Stenosis 40

Dr. Paddy Barrett

OCTOBER 31, 2023

An elevated Lp(a) is a common genetic factor that is independently and causally related to premature coronary artery disease. But we must always remember that most genetic risk factors are probabilistic rather than deterministic in terms of risk. Atherosclerosis. 2017 Jan;256:47-52. Eur J Clin Invest.

Coronary Artery Disease 52

Coronary Artery Disease Heart Disease Atherosclerosis Cardiovascular Disease 52

Cardiometabolic Health Congress

JANUARY 15, 2025

While advances in treatment have reduced mortality in some regions, the atherosclerosis prevention remains challenging. This shift results from an epidemiologic transition: as infectious diseases decline, chronic conditions like atherosclerosis dominate.

Atherosclerosis 59

Atherosclerosis Plaque Myocardial Infarction Risk Factors 59

MIBHS

FEBRUARY 28, 2025

Heart disease remains one of the leading causes of death worldwide, often attributed to a mix of lifestyle choices, environmental factors, and genetic predispositions. This blog explores how genetics influence heart health and whether mitigating these inherited risks is possible. How Do Genetic Factors Work?

Genetic predisposition 52

Genetic predisposition Heart Disease Cholesterol Blood Pressure 52

Dr. Paddy Barrett

SEPTEMBER 20, 2024

This Is Known As Atherosclerosis. The fundamental cause of atherosclerosis is when a cholesterol particle crosses into the artery wall from the bloodstream, gets stuck, and sets off an inflammatory process 1. ApoB particles crossing the artery wall to cause Atherosclerosis. No atherosclerosis. No heart attacks.

Heart Disease 111

Heart Disease Cholesterol Atherosclerosis Heart Attack 111

DAIC

MARCH 31, 2025

mg reduces the risk of major adverse cardiovascular events (MACE) and supports its use in the treatment of cardiovascular disease. Specifically, LODOCO reduces cardiac event risk in adult patients with established atherosclerotic cardiovascular disease by an additional 31% as compared to placebo.

Cardiovascular Disease 52

Cardiovascular Disease Plaque Coronary Artery Disease Heart Attack 52

Dr. Paddy Barrett

JANUARY 23, 2024

Share While the average Western male and female will develop advanced coronary artery disease by age 55 and 66, respectively, 85% of the Tsimane tribe population over 40 had no evidence of advanced atherosclerosis 2. Coronary atherosclerosis, as evidenced by an abnormal CAC score, is a measure of advanced plaque. Circulation.

Heart Disease 105

Heart Disease Blood Pressure Dementia Atherosclerosis 105

DAIC

JANUARY 23, 2024

1,6 Until recently atherosclerosis has been thought of as the result of passive lipid accumulation in the vessel wall. However, the development of atherosclerosis is now known to be much more complex, with a key role for immune cells and inflammation in conjunction with hyperlipidemia and elevated LDL levels.7

Cardiovascular Disease 111

Cardiovascular Disease Heart Attack Heart attacks Coronary Artery Disease 111

Stroke Journal

JANUARY 30, 2025

Results:Among the 9,444 participants included, the mean age was 57 (5.7 SD), and 43.2%

Atherosclerosis 40

Atherosclerosis Stroke Strokes Atrial Fibrillation 40

DAIC

MAY 29, 2024

Data presented today by AstraZeneca , at the European Atherosclerosis Society (EAS) Congress in France, on AZD0780, an oral PCSK9 inhibitor demonstrated significant LDL-C reduction on top of statin in Phase I trial. Elevated LDL-C levels in plasma is a key risk factor for cardiovascular disease and is estimated to cause 2.6

Cholesterol 52

Cholesterol Cardiovascular Disease Atherosclerosis Myocardial Infarction 52

Dr. Paddy Barrett

OCTOBER 4, 2024

Controlling LDL cholesterol. Control Risk Factors Early. The majority of risk can be managed with close attention to lifestyle factors, but for some, medications may be needed. The majority of risk can be managed with close attention to lifestyle factors, but for some, medications may be needed.

Heart Disease 104

Heart Disease Plaque Cholesterol Risk Factors 104

DAIC

FEBRUARY 1, 2024

February 1, 2024 — As cardiologists, heart disease patients and the organizations that serve them across the country embark on American Heart Month, DAIC has compiled a snapshot of significant cardiovascular disease (CVD) and stroke statistics, along with a review of the atherosclerosis drug market. percent Compound Annual Growth Rate (CAGR).

Cardiovascular Disease 104

Cardiovascular Disease Atherosclerosis Stroke Strokes 104

DAIC

MAY 16, 2024

. - Implementation of a multispecialty care team approach, including expertise in risk factor management, guideline directed medical therapies, wound and foot care and endovascular and surgical revascularization procedures, may improve outcomes for people with PAD. and Global Data From the American Heart Association.

Peripheral Arterial Disease 105

Peripheral Arterial Disease Exercise Ischemia Quality of Life 105

Physiologically Speaking

MARCH 6, 2024

For one, drugs target single pathways or risk factors. Statins lower cholesterol. Of course, exercise improves common cardiovascular risk factors like blood pressure, cholesterol, blood glucose, and it may even promote weight loss. In contrast, exercise targets several cells, tissues, and organs.

Exercise 92

Exercise Blood Pressure Risk Factors Physiology 92

DAIC

MARCH 31, 2025

mg reduces the risk of major adverse cardiovascular events (MACE) and supports its use in the treatment of cardiovascular disease. Specifically, LODOCO reduces cardiac event risk in adult patients with established atherosclerotic cardiovascular disease by an additional 31% as compared to placebo.

Cardiovascular Disease 52

Cardiovascular Disease Plaque Coronary Artery Disease Heart Attack 52

DAIC

JANUARY 30, 2024

A leading cause of death and disability, cardiovascular disease typically involves atherosclerotic arteries—those narrowed and stiffened by cholesterol—which are prone to develop blockages that cause heart attacks and strokes. This overlap contrasts with the traditional picture of a wide gap in risk between the two groups,” Mok says.

Cardiovascular Disease 52

Cardiovascular Disease Research Heart Attack Heart attacks 52

Heart 2023 Conference

APRIL 20, 2022

In patients who are not taking statins, Esperion announced that bempedoic acid with or without ezetimibe (Nexletol/Nexlizet) can lower LDL cholesterol by more than 25%.

Pulmonary 52

Pulmonary Hypertension AFIB COVID-19 52

The Beat Blog

MARCH 30, 2022

Four years on, it is still among the most extensive studies measuring the progression of cardiovascular diseases among initially healthy individuals and associating the costs of treating CVD with different risk factors. Age and future CVD costs correlated closely for male participants ages 45 to 64.

Blood Pressure 52

Blood Pressure Diabetes Risk Factors Cardiovascular Disease 52

Circulation: Cardiovascular Imaging

FEBRUARY 4, 2025

BACKGROUND:Immune checkpoint inhibitors (ICIs), though revolutionary in cancer treatment, may accelerate atherosclerosis by inducing arterial inflammation. Baseline arterial [18F]FDG uptake correlated with traditional cardiovascular risk factors, such as body mass index and male sex. annually in patients without ICIs (95% CI, 0.2%1.4%),

Cancer 40

Cancer Atherosclerosis Cardiovascular Imaging Cholesterol 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Apolipoprotein E4 (ApoE4) allele is linked to increased LDL-Cholesterol, one of the main risk factors for intracranial large artery stenosis (ICAS). While the link between ApoE4 and extracranial atherosclerosis and vascular risk factors is established, the association of these vascular factors with ICAS is unknown.

Stenosis 40

Stenosis Risk Factors Hypertension Dementia 40

Dr. Paddy Barrett

AUGUST 1, 2023

A CT CAC scan can only identify if there is calcified atherosclerosis, where it is and to what extent. A CT CAC scan of 0 indicates no significant amount of calcified atherosclerosis. It does not imply that there is NO advanced atherosclerosis. Share But why do a CT if risk factor modification is the priority?

Coronary Angiogram 52

Coronary Angiogram Plaque Coronary Artery Disease Chest Pain 52

Dr. Paddy Barrett

JULY 12, 2024

If you have high LDL cholesterol and are unsure what that means for your risk of heart disease, this article is for you. Over the course of your lifetime, your LDL cholesterol will slowly increase. By midlife, the average male and female will see a significant rise in their LDL cholesterol. to 4 mmol (135 to 155 mg/dl).

Cholesterol 105

Cholesterol Heart Attack Heart attacks Blood Pressure 105

Dr. Paddy Barrett

OCTOBER 10, 2023

Share Here are seven things you can assess to see if you have excess risk lurking underneath the surface. Lipoprotein (a) Approximately 1 in 5 people have the Lp(a) variant of cholesterol particle that significantly increases the risk of early heart disease and stroke. The greater the number of particles, the higher the risk.

Risk Factors 52

Risk Factors Heart Disease Blood Pressure Coronary Artery Disease 52

Dr. Paddy Barrett

MAY 31, 2024

These noninvasive scans look directly at the coronary arteries rather than assessing for the risk factors for coronary artery disease eg LDL cholesterol, high blood pressure etc. Atherosclerosis in the proximal segment of the vessel. CT Coronary Angiogram. But waiting for the appearance of calcification is a bad idea.

Heart Disease 96

Heart Disease Plaque Heart Attack Heart attacks 96