Dr. Paddy Barrett

JANUARY 24, 2025

I am a fan of using low-carb diets for both weight loss and improving metabolic health. Low-carb diets have consistently shown benefits in improving these parameters 1. In the early 1970’s a group of 106 severely obese patients were put on a diet that resulted in an average weight loss of 63 Kg (139 lbs) over about one year 2.

Diet 52

Diet Obesity Diabetes Cholesterol 52

MIBHS

AUGUST 15, 2024

Blood Vessels: Chronic stress can impair the function of the endothelium—the lining of blood vessels—potentially leading to atherosclerosis, a precursor to heart disease. Lipid Metabolism: Chronic stress can alter lipid metabolism, potentially increasing bad cholesterol (LDL) and decreasing good cholesterol (HDL).

Blood Pressure 52

Blood Pressure Cholesterol Heart Disease Diet 52

Stroke Journal

JANUARY 30, 2025

Background:PCSK9, a key regulator of cholesterol metabolism, has been implicated in atherosclerosis. PCSK9 overexpression was induced via AAV injection, and mice were subjected to either a normal diet or HFD for 4 months. Stroke, Volume 56, Issue Suppl_1 , Page ADP14-ADP14, February 1, 2025.

Diet 40

Diet Dementia Atherosclerosis Cholesterol 40

Cardiometabolic Health Congress

JANUARY 15, 2025

While advances in treatment have reduced mortality in some regions, the atherosclerosis prevention remains challenging. This shift results from an epidemiologic transition: as infectious diseases decline, chronic conditions like atherosclerosis dominate.

Atherosclerosis 59

Atherosclerosis Plaque Myocardial Infarction Risk Factors 59

MIBHS

FEBRUARY 28, 2025

While much attention is given to modifiable risk factors such as diet, exercise, and smoking, the role of genetics in heart disease is equally critical yet less understood by the general public. Specific genetic variants, such as those affecting cholesterol metabolism, can increase the likelihood of plaque buildup in the arteries.

Genetic predisposition 52

Genetic predisposition Heart Disease Cholesterol Blood Pressure 52

Physiologically Speaking

FEBRUARY 23, 2024

High-protein diets are often advocated for building muscle, losing weight, and optimizing body composition. Eating this amount of protein means your diet will comprise about 11% of calories from protein, leaving fat and carbs to fill the gaps. In simpler terms: In mice, a high-protein (and hence high-amino-acid) diet activates mTORC1.

Physiology 111

Physiology Atherosclerosis Diet Cardiovascular Disease 111

Frontiers in Cardiovascular Medicine

FEBRUARY 16, 2024

Introduction Atherosclerosis is a chronic inflammatory disease caused by the deposition of lipids within the artery wall. During atherogenesis, efficient autophagy is needed to facilitate efferocytosis and cholesterol efflux, limit inflammation and lipid droplet buildup, and eliminate defective mitochondria and protein aggregates.

Atherosclerosis 64

Atherosclerosis Plaque Diet Cholesterol 64

Dr. Paddy Barrett

JANUARY 23, 2024

Share While the average Western male and female will develop advanced coronary artery disease by age 55 and 66, respectively, 85% of the Tsimane tribe population over 40 had no evidence of advanced atherosclerosis 2. Coronary atherosclerosis, as evidenced by an abnormal CAC score, is a measure of advanced plaque. In my view.

Heart Disease 106

Heart Disease Blood Pressure Dementia Atherosclerosis 106

DAIC

MAY 16, 2024

PAD is a serious, progressive cardiovascular disease primarily caused by a buildup of fatty plaque in the blood vessels, or atherosclerosis. This plaque narrows the blood vessels and reduces blood flow to the legs and feet, which may significantly impair physical function, walking performance and quality of life.

Peripheral Arterial Disease 105

Peripheral Arterial Disease Exercise Ischemia Quality of Life 105

Dr. S. Venkatesan MD

JANUARY 8, 2024

10kg) Out of which just 250 mg of cholesterol is streaming in blood. We must understand Fat, lipid and cholesterol are different entities. LDL is obviously a target against atherosclerosis. Chasing LDL cholesterol to the bottom — PCSK9 in perspective. Preamble 15 % of body weight is fat. Mind you LDL constitutes.000025%

Cholesterol 52

Cholesterol Atherosclerosis Plaque Physiology 52

Frontiers in Cardiovascular Medicine

DECEMBER 20, 2024

Cholesterol aggregation in dendritic cells (DCs) triggers an inflammatory response and accelerates the development of atherosclerosis (AS). Resveratrol (RES), a natural compound with anti-inflammatory and cholesterol metabolism regulatory properties, has been shown to influence the maturation and inflammatory functions of DCs.

Cholesterol 52

Cholesterol Diet Atherosclerosis Research 52