Remove Atherosclerosis Remove Cholesterol Remove Dementia
article thumbnail

Cholesterol’s Star Role in Dementia Prevention: New Insights from the 2024 Lancet Dementia Report 

Cardiometabolic Health Congress

The 2024 report from the Lancet Standing Commission on Dementia Prevention, Intervention, and Care brings promising developments for healthcare professionals and public health advocates. Key Takeaways: Up to 50% of all dementia cases could potentially be prevented or substantially delayed. Presented by Pamela B.

article thumbnail

Do Statins Cause Dementia?

Dr. Paddy Barrett

I am going to start with the answer to the question of whether statins cause dementia and then provide the details backing up my answer. Statins do not cause dementia. But if you are someone who thinks that statins do cause dementia and you need to see the evidence to refute that claim, then read on. The answer is: No.

article thumbnail

APOE4 & Cardiovascular Risk

Dr. Paddy Barrett

Being a carrier of the APOE4 gene variant is associated with higher rates of the most common type of dementia, late-onset dementia. Of those with late-onset dementia, up to 65% are carriers of the APOE4 gene variant 1. Of those with late-onset dementia, up to 65% are carriers of the APOE4 gene variant 1.

article thumbnail

Beating the Odds: Inside the Tribe with a Near-Zero Rate of Heart Disease.

Dr. Paddy Barrett

Share While the average Western male and female will develop advanced coronary artery disease by age 55 and 66, respectively, 85% of the Tsimane tribe population over 40 had no evidence of advanced atherosclerosis 2. Coronary atherosclerosis, as evidenced by an abnormal CAC score, is a measure of advanced plaque. Circulation.

article thumbnail

Abstract WP239: Apolipoprotein E4 Allele Effect on the Prevalence of Intracranial Large Artery Stenosis

Stroke Journal

Introduction:Apolipoprotein E4 (ApoE4) allele is linked to increased LDL-Cholesterol, one of the main risk factors for intracranial large artery stenosis (ICAS). While the link between ApoE4 and extracranial atherosclerosis and vascular risk factors is established, the association of these vascular factors with ICAS is unknown.