DAIC

JANUARY 23, 2024

Atherosclerotic cardiovascular disease (ASCVD), caused by plaque buildup in arterial walls, is one of the leading causes of disability and death worldwide.1,2 1,2 ASCVD causes or contributes to conditions that include coronary artery disease (CAD), cerebrovascular disease, and peripheral vascular disease (inclusive of aortic aneurysm).3

Cardiovascular Disease 111

Cardiovascular Disease Heart Attack Heart attacks Coronary Artery Disease 111

Cardiometabolic Health Congress

NOVEMBER 22, 2024

Another promising advancement is MK-0616 , an oral PCSK9 inhibitor in Phase 3 trials, showing a significant reduction in LDL cholesterol, which provides a more convenient alternative to current injection-based therapies​.

Blood Pressure 52

Blood Pressure Obesity Preserved Ejection Fraction Coronary Artery Disease 52

Dr. Paddy Barrett

JANUARY 23, 2024

By age 66, more than half of all females will have evidence of advanced plaque in their coronary arteries, as seen on a CT calcium score. Subscribe now But are there groups who buck this trend and rarely develop coronary artery disease and, by extension, do not die from it early in life? The answer is yes.

Heart Disease 94

Heart Disease Blood Pressure Dementia Atherosclerosis 94

Stroke Journal

FEBRUARY 1, 2024

Background:Lipoprotein a (Lp(a)) is known to be associated with coronary artery disease and carotid artery atherosclerosis. This association remains independent even after adjustment for factors such as statin use or low-density lipoprotein cholesterol (LDL-C) levels.

Plaque 40

Plaque Coronary Artery Disease Ultrasound Atherosclerosis 40

Dr. Paddy Barrett

OCTOBER 4, 2024

But the goal in this instance is to die after a long and healthy life ‘ with ’ coronary artery disease rather than ‘ from ’ coronary artery disease. However, the chances of dying from heart disease are directly proportional to the amount of plaque in your coronary arteries.

Heart Disease 74

Heart Disease Plaque Cholesterol Risk Factors 74

Dr. Paddy Barrett

AUGUST 1, 2023

CT coronary angiography, in addition to a CT CAC, is arguably the best test for estimating whether someone has evidence of coronary artery disease and what that means for their near-term risk of a heart attack. A CT CAC scan can only identify if there is calcified atherosclerosis, where it is and to what extent.

Coronary Angiogram 52

Coronary Angiogram Plaque Coronary Artery Disease Chest Pain 52

Dr. Paddy Barrett

AUGUST 22, 2023

Every lipoprotein particle has one APO B protein. ( **Please note the B ) When we measure APO B levels, this is what we are measuring to give an estimate of the number of cholesterol particles and the subsequent risk of cardiovascular disease. APO E is also centrally involved in cholesterol metabolism. Here’s how.

Cholesterol 52

Cholesterol Dementia Cardiovascular Disease Coronary Artery Disease 52

Dr. Paddy Barrett

OCTOBER 31, 2023

An elevated Lp(a) is a common genetic factor that is independently and causally related to premature coronary artery disease. The occurrence of disease in this instance is probabilistic, not deterministic. An elevated Lp(a) does increase the risk of early cardiovascular disease, but that risk is not set in stone.

Coronary Artery Disease 52

Coronary Artery Disease Heart Disease Atherosclerosis Cardiovascular Disease 52

Dr. Paddy Barrett

SEPTEMBER 19, 2023

I do apologise for being direct, but this issue is one of the most frequent barriers I encounter to initiating cholesterol-lowering therapy. At the exact same time, cholesterol concentrations are also at their lowest. At the exact same time, cholesterol concentrations are also at their lowest. Let’s break this down.

Dementia 52

Dementia Cholesterol Biomarkers Coronary Artery Disease 52

Physiologically Speaking

JANUARY 5, 2024

Importantly, all of the participants had recently undergone percutaneous coronary intervention (PCI) — a surgical procedure in which a stent is placed in a coronary artery to open up a blockage. All of the participants had stable coronary artery disease and were on lipid-lowering therapies during the study.

Plaque 114

Plaque Physiology Exercise Cholesterol 114

DAIC

MAY 16, 2024

PAD is a serious, progressive cardiovascular disease primarily caused by a buildup of fatty plaque in the blood vessels, or atherosclerosis. Among those ages 65 and older, nearly 50% who underwent limb amputation died within one year after surgery, according to the 2024 Heart Disease and Stroke Statistics: A Report of U.S.

Peripheral Arterial Disease 105

Peripheral Arterial Disease Exercise Quality of Life Ischemia 105

Wellnest

DECEMBER 21, 2022

Coronary artery disease Excessive cholesterol builds up plaque that blocks the arteries supplying blood to the heart. This condition is also called atherosclerosis. ECG machine can also help diagnose coronary artery disease. Early detection is vital in the treatment of CAD.

Cardiac Arrest 52

Cardiac Arrest Heart Attack Heart attacks Atrial Fibrillation 52

Dr. Paddy Barrett

MAY 31, 2024

The most common way to assess the presence and extent of coronary artery disease is with a CT scan, called a CT CAC score or CT Coronary Angiogram. CT Coronary Angiogram. Atherosclerosis in the proximal segment of the vessel. But waiting for the appearance of calcification is a bad idea. Here’s why.

Heart Disease 77

Heart Disease Plaque Heart Attack Heart attacks 77

Dr. Paddy Barrett

OCTOBER 10, 2023

Even in those with documented coronary artery disease, less than half were on statin therapy, which has been repeatedly proven to decrease risk in this high-risk group 1. It is genetically mediated, so if you have an early family history of heart disease, this is something to consider 2. J Am Coll Cardiol. JAMA Cardiol.

Risk Factors 52

Risk Factors Heart Disease Blood Pressure Coronary Artery Disease 52