CTVS

SEPTEMBER 17, 2024

PAD is a serious condition affecting circulation and blood vessels, causing them to narrow from plaque buildup in the arteries and blocking blood flow to the extremities, typically the legs and feet. It is triggered by atherosclerosis, which occurs when fatty deposits or cholesterol accumulates… Source

Peripheral Arterial Disease 52

Peripheral Arterial Disease Plaque Atherosclerosis Cholesterol 52

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4125511-A4125511, November 12, 2024. Conclusions:There is an L-shaped association between NHHR levels and atherosclerosis in adults in the United States, and controlling NHHR is clinically important for reducing the risk of developing atherosclerosis.

Cholesterol 40

Cholesterol Atherosclerosis Cardiovascular Disease Hypertension 40

Circulation

JANUARY 24, 2024

Circulation, Ahead of Print.

Heart Disease 81

Heart Disease Peripheral Arterial Disease Stroke Strokes 81

Dr. Paddy Barrett

NOVEMBER 7, 2023

The fundamental characteristic of atherosclerosis is when a cholesterol particle becomes trapped in the artery wall. It is the inflammatory response to this particle retention that causes the formation of atherosclerosis 1. Lipoprotein particles entering the subintimal space causing atherosclerosis. TG = Triglycerides.

Cholesterol 52

Cholesterol Atherosclerosis Stenosis Aortic 52

Circulation: Genomic and Precision Medicine

JULY 6, 2023

Circulation: Genomic and Precision Medicine, Volume 16, Issue 5 , Page 480-482, October 1, 2023.

Coronary Artery Disease 40

Coronary Artery Disease Cholesterol Atherosclerosis Circulation 40

Dr. Paddy Barrett

AUGUST 22, 2023

Every lipoprotein particle has one APO B protein. ( **Please note the B ) When we measure APO B levels, this is what we are measuring to give an estimate of the number of cholesterol particles and the subsequent risk of cardiovascular disease. APO E is also centrally involved in cholesterol metabolism. Here’s how. What to do?

Cholesterol 52

Cholesterol Dementia Coronary Artery Disease Cardiovascular Disease 52

Dr. Paddy Barrett

SEPTEMBER 19, 2023

I do apologise for being direct, but this issue is one of the most frequent barriers I encounter to initiating cholesterol-lowering therapy. At the exact same time, cholesterol concentrations are also at their lowest. At the exact same time, cholesterol concentrations are also at their lowest. Let’s break this down.

Dementia 52

Dementia Cholesterol Biomarkers Coronary Artery Disease 52

Circulation

OCTOBER 20, 2023

Circulation, Ahead of Print. BACKGROUND:Homozygous familial hypercholesterolemia (HoFH) is a rare genetic disorder characterized by severely elevated low-density lipoprotein cholesterol (LDL-C) levels due to profoundly defective LDLR (LDL receptor) function.

Pediatrics 40

Pediatrics Cholesterol Atherosclerosis Circulation 40

GEMMS

NOVEMBER 22, 2023

Factors such as smoking, high blood pressure, high cholesterol levels, obesity, and a sedentary lifestyle significantly increase the risk of developing cardiovascular disease. Engaging in activities such as running, swimming, or cycling helps strengthen the heart, increase lung capacity, and improve blood circulation.

Blood Pressure 52

Blood Pressure Cholesterol Diet Exercise 52

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4141400-A4141400, November 12, 2024. They contain dietary triglycerides, cholesterols, and apolipoproteins. Introduction:Chylomicrons are major lipid fuel for cells. In the intestine, apolipoprotein C-III (apoC-III) is produced during fat feeding, and secreted onto chylomicrons.

Cardiovascular Disease 40

Cardiovascular Disease Cholesterol Atherosclerosis Circulation 40

The British Journal of Cardiology

AUGUST 1, 2024

Currently, there is no specific treatment to lower its circulating concentration. Lipoprotein(a) (Lp[a]) can improve the accuracy of assessment of atherosclerotic cardiovascular disease and the risk of aortic valve stenosis. Raised Lp(a) is a feature of familial hypercholesterolaemia.

Aortic valve 40

Aortic valve Heart Disease Blood Pressure Stenosis 40

MIBHS

FEBRUARY 28, 2025

Genes influence various biological processes, including cholesterol metabolism, blood pressure regulation, and the strength and structure of your heart and blood vessels. Specific genetic variants, such as those affecting cholesterol metabolism, can increase the likelihood of plaque buildup in the arteries. How Do Genetic Factors Work?

Genetic predisposition 52

Genetic predisposition Heart Disease Cholesterol Blood Pressure 52

Dr. Paddy Barrett

SEPTEMBER 20, 2024

This Is Known As Atherosclerosis. The fundamental cause of atherosclerosis is when a cholesterol particle crosses into the artery wall from the bloodstream, gets stuck, and sets off an inflammatory process 1. ApoB particles crossing the artery wall to cause Atherosclerosis. No atherosclerosis. No heart attacks.

Heart Disease 111

Heart Disease Cholesterol Atherosclerosis Heart Attack 111

DAIC

MARCH 31, 2025

The study, Effect of Colchicine on Progression of Known Coronary Atherosclerosis in Patients With Stable Coronary Artery Disease Compared To Placebo: The Ekstrom Trial, was presented at the American College of Cardiology 74th Annual Scientific Session and Expo ( ACC.25

Cardiovascular Disease 52

Cardiovascular Disease Plaque Coronary Artery Disease Heart Attack 52

Frontiers in Cardiovascular Medicine

FEBRUARY 16, 2024

Introduction Atherosclerosis is a chronic inflammatory disease caused by the deposition of lipids within the artery wall. During atherogenesis, efficient autophagy is needed to facilitate efferocytosis and cholesterol efflux, limit inflammation and lipid droplet buildup, and eliminate defective mitochondria and protein aggregates.

Atherosclerosis 64

Atherosclerosis Plaque Diet Cholesterol 64

DAIC

JANUARY 23, 2024

1,6 Until recently atherosclerosis has been thought of as the result of passive lipid accumulation in the vessel wall. However, the development of atherosclerosis is now known to be much more complex, with a key role for immune cells and inflammation in conjunction with hyperlipidemia and elevated LDL levels.7

Cardiovascular Disease 111

Cardiovascular Disease Heart Attack Heart attacks Coronary Artery Disease 111

Dr. Paddy Barrett

JANUARY 23, 2024

Share While the average Western male and female will develop advanced coronary artery disease by age 55 and 66, respectively, 85% of the Tsimane tribe population over 40 had no evidence of advanced atherosclerosis 2. Coronary atherosclerosis, as evidenced by an abnormal CAC score, is a measure of advanced plaque. Circulation.

Heart Disease 105

Heart Disease Blood Pressure Dementia Atherosclerosis 105

DAIC

FEBRUARY 1, 2024

February 1, 2024 — As cardiologists, heart disease patients and the organizations that serve them across the country embark on American Heart Month, DAIC has compiled a snapshot of significant cardiovascular disease (CVD) and stroke statistics, along with a review of the atherosclerosis drug market. percent Compound Annual Growth Rate (CAGR).

Cardiovascular Disease 104

Cardiovascular Disease Atherosclerosis Stroke Strokes 104

Dr. Paddy Barrett

OCTOBER 4, 2024

Controlling LDL cholesterol. Let's take a 42-year-old male with an LDL cholesterol of 5.1 How much would they benefit from going on a cholesterol lowering medication? Now add in an elevated Lp(a), which is a common genetic cholesterol particle disorder, and that risk reduction gets even bigger. Circulation.

Heart Disease 104

Heart Disease Plaque Cholesterol Risk Factors 104

Stroke Journal

JANUARY 21, 2024

BACKGROUND:Sex-specific differences in plaque composition and instability underscore the need to explore circulating markers for better prediction of high-risk plaques. Antagonistic interactions between sex and white blood cell (WBC) counts, basophil-to-WBC ratio, and platelet counts influenced plaque instability.

Plaque 40

Plaque Circulation Atherosclerosis Hemorrhage 40

DAIC

MARCH 31, 2025

The study, Effect of Colchicine on Progression of Known Coronary Atherosclerosis in Patients With Stable Coronary Artery Disease Compared To Placebo: The Ekstrom Trial, was presented at the American College of Cardiology 74th Annual Scientific Session and Expo ( ACC.25

Cardiovascular Disease 52

Cardiovascular Disease Plaque Coronary Artery Disease Heart Attack 52

Circulation: Cardiovascular Imaging

FEBRUARY 4, 2025

Circulation: Cardiovascular Imaging, Ahead of Print. BACKGROUND:Immune checkpoint inhibitors (ICIs), though revolutionary in cancer treatment, may accelerate atherosclerosis by inducing arterial inflammation. Baseline arterial [18F]FDG uptake correlated with traditional cardiovascular risk factors, such as body mass index and male sex.

Cancer 40

Cancer Atherosclerosis Cardiovascular Imaging Cholesterol 40

DAIC

MAY 16, 2024

PAD is a serious, progressive cardiovascular disease primarily caused by a buildup of fatty plaque in the blood vessels, or atherosclerosis. This plaque narrows the blood vessels and reduces blood flow to the legs and feet, which may significantly impair physical function, walking performance and quality of life.

Peripheral Arterial Disease 105

Peripheral Arterial Disease Exercise Ischemia Quality of Life 105

Dr. Paddy Barrett

MAY 31, 2024

These noninvasive scans look directly at the coronary arteries rather than assessing for the risk factors for coronary artery disease eg LDL cholesterol, high blood pressure etc. Atherosclerosis in the proximal segment of the vessel. Atherosclerosis, or plaque, is a progressive condition that occurs in stages over decades.

Heart Disease 96

Heart Disease Plaque Heart Attack Heart attacks 96